Dr. Zhiyou Yang

Assistant Professor
Guangdong Ocean University, China


Highest Degree
Ph.D. in Neuromedical Sciences from University of Toyama, Japan

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Area of Interest:

Biomedical Sciences
Medical Sciences
Neurodegenerative Disease
Alzheimer`s Disease
Neuroendocrinology

Selected Publications

  1. Yang, Z., T. Kuboyama and C. Tohda, 2019. Naringenin promotes microglial M2 polarization and Aβ degradation enzyme expression. Phytother. Res., 33: 1114-1121.
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  2. Song, C., Y.S. Wu, Z.Y. Yang, A.V. Kalueff, Y.Y. Tsao, Y. Dong and K.P. Su, 2019. Astrocyte-conditioned medium protects prefrontal cortical neurons from glutamate-induced cell death by inhibiting TNF-α expression. NeuroimmunoModulation, 26: 33-42.
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  3. Ling, Y., Z. Yang, W. Huang, Y. Zhang and W. Yang et al., 2019. Effect of ethanol extract of lined hippocampus on inflammatory response of BV2 microglia induced by lipopolysaccharide. J. Guangdong Ocean Univ., 39: 90-96.
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  4. Chang, S., Z. Yang, N. Han, Z. Liu and J. Yin, 2018. The antithrombotic, anticoagulant activity and toxicity research of ambinine, an alkaloid from the tuber of Corydalis ambigua var. amurensis. Regul. Toxicol. Pharmacol., 95: 175-181.
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  5. Yang, Z., T. Kuboyama and C. Tohda, 2017. A systematic strategy for discovering a therapeutic drug for Alzheimer’s disease and its target molecule. Front. Pharmacol., Vol. 8. 10.3389/fphar.2017.00340.
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  6. Liu, Z.H., Q. Li, S. Chang, Z.Y. Yang, N. Han and J. Yin, 2016. Protective effect of hexahydrobenzo [c] phenanthridine alkaloids isolated from Corydalis ambigua var. amurensis on myocardial ischemia-hypoxia cells. Phytochem. Lett., 17: 258-262.
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  7. Han, N., Z. Yang, Z. Liu, H. Liu and J. Yin, 2016. Research progress on natural benzophenanthridine alkaloids and their pharmacological functions: A review. Nat. Prod. Commun., 11: 1181-1188.
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  8. Yang, Z.Y., T. Kuboyama, K. Kazuma, K. Konno and C. Tohda, 2015. Active constituents from Drynaria fortune rhizomes on the attenuation of Aβ25-35-induced axonal atrophy. J. Nat. Prod., 78: 2297-2300.
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  9. Yang, Z.Y., B.H. Jiang, F.K. Teng, N. Han and Z.H. Liu et al., 2014. Ambiguanine A-G, hexahydrobenzophenanthridine alkaloids from Corydalis ambigua var. amurensis. Phytochemistry, 105: 158-163.
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  10. Yang, Z., Z. Liu, B. Jiang, F. Teng and Y. Wang et al., 2014. Ambidalmines A-E and ambidimerine F: Bioactive dihydrobenzophenanthridine alkaloids from Corydalis ambigua var. amurensis. Eur. J. Med. Chem., 84: 417-424.
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  11. Hu, D., Z. Yang, X. Yao, H. Wang and N. Han et al., 2014. Dibenzocyclooctadiene lignans from Schisandra chinensis and their inhibitory activity on NO production in lipopolysaccharide-activated microglia cells. Phytochemistry, 104: 72-78.
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