Dr. Ying Peng

Professor
Sun Yat-Sen University, China

Highest Degree
Ph.D. in Neurology from Sun Yat-Sen University of Medical Sciences, China

My URL
https://livedna.org/86.6037

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Area of Interest:

Biomedical Sciences
Neurological Pain
Toxic Encephalopathy
Gene Therapy
Oncology

Selected Publications

  1. Yue, P.J., L. He, Y. Li, Q.Y. Shen and M. Li et al., 2013. Preclinical safety evaluation of rAd5-hTERTC27 by intravenous injection. Regul. Toxicol. Pharmacol., 67: 53-62.
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  2. Qiu, S., S. Lin, D. Hu, Y. Feng, Y. Tan and Y. Peng, 2013. Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients. J. Trans. Med., Vol. 11. 10.1186/1479-5876-11-10.
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  3. Qiu, S., D. Huang, F. Li, D. Yin, H.F. Kung and Y. Peng, 2013. Suppression of tumorigenicity by MicroRNA-138 through inhibition of EZH2-CDK4/6-pRb-E2F1 signal loop in glioblastoma multiforme. Biochim. Biophys. Acta (BBA)-Mol. Basis Dis., 1832: 1697-1707.
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  4. Liu, X., J. Lu, M.L. He, Z. Li and B. Zhang et al., 2013. Antitumor effects of interferon-alpha on cell growth and metastasis in human nasopharyngeal carcinoma. Curr. Cancer Drug Targets, 12: 561-570.
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  5. Li, Y., X. Shi, X. Rong, Y. Peng and Y. Tang, 2013. Neurosurgery and prognosis in patients with radiation-induced brain injury after nasopharyngeal carcinoma radiotherapy: A follow-up study. Radiat. Oncol., Vol. 8. 10.1186/1748-717X-8-88.
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  6. Li, H., R. Pan, H. Wang, X. Rong and Z. Yin et al., 2013. Clipping versus coiling for ruptured intracranial aneurysms: A systematic review and meta-analysis. Stroke, 44: 29-37.
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  7. Li, D., X.P. Li, H.X. Wang, Q.Y. Shen and X.P. Li et al., 2013. VEGF induces angiogenesis in a zebrafish embryo glioma model established by transplantation of human glioma cells. Oncol. Rep., 28: 937-942.
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  8. Li, C., X. Li, Q. Shen, Y. Li and L. He et al., 2013. Critical role of matrix metalloproteinase-9 in acute cold exposure-induced stroke in renovascular hypertensive rats. J. Stroke Cerebrovasc. Dis., 22: 477-485.
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  9. He, L., M. Li, X.H. Long, X.P. Li and Y. Peng, 2013. A case of Hashimoto's encephalopathy misdiagnosed as viral encephalitis. Am. J. Case Rep., 14: 366-369.
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  10. He, L., H.X. Gong, X.P. Li, Y.D. Wang and Y. Li et al., 2013. Inhibition of hepatocellular carcinoma growth by adenovirus-mediated expression of human telomerase reverse transcriptase COOH-27 terminal polypeptide in mice. Oncol. Lett., 6: 748-752.
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  11. Zhao, J., L. Li, Z. Pei, C. Li and H. Wei et al., 2012. Peroxisome proliferator activated receptor (PPAR)-γ co-activator 1-α and hypoxia induced factor-1α mediate neuro- and vascular protection by hypoxic preconditioning in vitro. Brain Res., 1447: 1-8.
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  12. Tang, Y., D. Luo, X. Rong, X. Shi and Y. Peng, 2012. Psychological disorders, cognitive dysfunction and quality of life in nasopharyngeal carcinoma patients with radiation-induced brain injury. PLoS One, Vol. 7. 10.1371/journal.pone.0036529.
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  13. Rong, X., Y. Tang, M. Chen, K. Lu and Y. Peng, 2012. Radiation-induced cranial neuropathy in patients with nasopharyngeal carcinoma. Strahlenther. Onkol., 188: 282-286.
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  14. Gong, H.X., L. He, X.P. Li, Y.D. Wang and Y. Li et al., 2012. Effective antitumor immunity against murine gliomas using dendritic cells transduced with hTERTC27 recombinant adenovirus. Oncol. Rep., 27: 1163-1169.
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  15. Tang, Y., Y. Li, D. Luo, X. Rong, J. Ye and Y. Peng, 2011. Epilepsy related to radiotherapy in patients with nasopharyngeal carcinoma. Epilepsy Res., 96: 24-28.
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  16. Tang, Y., X. Li, Y. Li, Q. Shen, X. Rong, R. Huang and Y. Peng, 2011. Renovascular hypertension causes cerebral vascular remodeling. Neural Regeneration Res., 6: 1977-1981.

  17. Tang, Y., Q. Shen, Y. Wang, K. Lu, Y. Wang and Y. Peng, 2011. A randomized prospective study of rehabilitation therapy in the treatment of radiation-induced dysphagia and trismus. Strahlenther. Onkol., 187: 39-44.
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  18. Lu, J., M.L. He, L. Wang, Y. Chen and X. Liu et al., 2011. MiR-26a inhibits cell growth and tumorigenesis of nasopharyngeal carcinoma through repression of EZH2. Cancer Res., 71: 225-233.
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  19. Wang, Y.D., X.P. Li, M. Li, S. Liu, X.P. Lu, Y. Peng and R.X. Huang, 2010. Relationship between cerebral hypoxic tissue volume and prognosis after stroke. Eur. Neurol., 63: 52-59.
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  20. Tang, Y., D. Luo, W. Peng, F. Huang and Y. Peng, 2010. Ocular ischemic syndrome secondary to carotid artery occlusion as a late complication of radiotherapy of nasopharyngeal carcinoma. J. Neuro-Ophthalmol., 30: 315-320.
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  21. Peng, K., Y. Li, L. Long, D. Li and Q. Jia et al., 2010. Knockdown of FoxO3a induces increased neuronal apoptosis during embryonic development in zebrafish. Neurosci. Lett., 484: 98-103.
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  22. Pan, J.R., Y. Li, Z. Pei, X.P. Li, Y. Peng and Y.D. Wang, 2010. Hypoxic tissues are associated with microvessel density following brain ischemia-reperfusion. Neurol. Sci., 31: 765-771.
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  23. Lum, C.T., X. Liu, R.W. Sun, X.P. Li and Y. Peng et al., 2010. Gold(III) porphyrin 1a inhibited nasopharyngeal carcinoma metastasis in vivo and inhibited cell migration and invasion in vitro. Cancer Lett., 294: 159-166.
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  24. Long, L., Y. Li, Y.D. Wang, Q.Y. He and M. Li et al., 2010. The preventive effect of oral EGCG in a fetal alcohol spectrum disorder mouse model. Alcoholism: Clin. Exp. Res., 34: 1929-1936.
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  25. Li, Y., H. Li, Y. Zhang, X. Sun and G. Hanley et al., 2010. Toll-like receptor 2 is required for opioids-induced neuronal apoptosis. Biochem. Biophys. Res. Commun., 391: 426-430.
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  26. Li, M., L. Wang, Y. Peng, J.C. Wang and L.H. Zhou, 2010. Knockdown of the neuronal nitric oxide synthase gene retard the development of the cerebellar granule neurons in vitro. Dev. Dyn., 239: 474-481.
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  27. Li, G., Z. Wu, Y. Peng, X. Liu and J. Lu et al., 2010. MicroRNA-10b induced by Epstein-Barr virus-encoded latent membrane protein-1 promotes the metastasis of human nasopharyngeal carcinoma cells. Cancer Lett., 299: 29-36.
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  28. Li, D., K. Peng, Y. Li and Y. Peng, 2010. Advancements on the zebrafish glioma model. Chinese J. Cancer, 29: 621-625.
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  29. Zhang, B., Y.X. Bai, H.H. Ma, F. Feng and R. Jin et al., 2009. Silencing PinX1 compromises telomere length maintenance as well as tumorigenicity in telomerase-positive human cancer cells. Cancer Res., 69: 75-83.
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  30. Yang, L., R. Lu, L. Jiang, Z. Liu and Y. Peng, 2009. Expression and genetic analysis of tumor necrosis factor-alpha (TNF-α) G-308A polymorphism in sporadic Alzheimer's disease in a Southern China population. Brain Res., 1247: 178-181.
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  31. Xia, S., C. Duan, Q. Shen, Y. Xing, Y. Peng, E. Tao and J. Liu, 2009. Neuron-specific enolase expression in a rat model of radiation-induced brain injury following vascular endothelial growth factor-modified neural stem cell transplantation. Neural Regen. Res., 4: 739-743.
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  32. Wang, Y., J. Pan, Y. Qiu, X. Li, M. Li and Y. Peng, 2009. Long-term existence of cerebral hypoxic tissue in a rat model of cereral ischemia/reperfusion injury. Neural Regen. Res., 4: 371-376.

  33. Liang, B., M.L. He, C.Y. Chan, Y.C. Chen and X.P. Li et al., 2009. The use of folate-PEG-grafted-hybranched-PEI nonviral vector for the inhibition of glioma growth in the rat. Biomaterials, 30: 4014-4020.
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  34. Li, Z., M.L. He, H. Yao, Q.M. Dong and Y.C. Chen et al., 2009. Inhibition of HBV replication and gene expression in vitro and in vivo with a single AAV vector delivering two shRNA molecules. BMB Rep., 42: 59-64.
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  35. Li, Y., X. Sun, Y. Zhang, J. Huang and G. Hanley et al., 2009. Morphine promotes apoptosis via TLR2 and this is negatively regulated by beta-arrestin 2. Biochem. Biophys. Res. Commun., 378: 857-861.
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  36. Yang, P.H., W.K. Cheung, Y. Peng, M.L. He and G.Q. Wu et al., 2008. Makorin-2 is a neurogenesis inhibitor downstream of phosphatidylinositol 3-kinase/Akt (PI3K/Akt) signal. J. Biol. Chem., 283: 8486-8495.
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  37. Tang, Y., Y. Zhang, L. Guo, Y. Peng, Q. Luo and Y. Xing, 2008. Relationship between individual radiosensitivity and radiation encephalopathy of nasopharyngeal carcinoma after radiotherapy. Strahlenther. Onkol., 184: 510-514.
    CrossRef  |  

  38. Lu, R., Q. Shen, L. Yang, M. Li, Y. Wang and Y. Peng, 2008. Effects of Kallikrein gene transfer on penumbral microvascular proliferation and regional cerebral blood flow following cerebral ischemia/reperfusion injury. Neural Regen. Res., 3: 1045-1050.

  39. Lu, R., L. Yang, Q. Shen, M. Li, X. Li and Y. Peng, 2008. Stereotaxic microinjection of adenovirus-mediated human tissue Kallikrein gene reduces apoptosis in a rat model of middle cerebral artery occlusion. Neural Regen. Res., 3: 847-852.

  40. Liang, B., M.L. He, Z.P. Xiao, Y. Li and C.Y. Chan et al., 2008. Synthesis and characterization of folate-PEG-grafted-hyperbranched-PEI for tumor-targeted gene delivery. Biochem. Biophys. Res. Commun., 367: 874-880.
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  41. Li, Z., H. Yao, Y. Ma, Q. Dong and Y. Chen et al., 2008. Inhibition of HBV gene expression and replication by stably expressed interferon-α 1 via adeno-associated viral vectors. J. Gene Med., 10: 619-627.
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  42. Wang, J., Y. Yang, H.H. Xia, Q. Gu and M.C. Lin et al., 2007. Suppression of FHL2 expression induces cell differentiation and inhibits gastric and colon carcinogenesis. Gastroenterology, 132: 1066-1076.
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  43. Ng, S.S., Y.T. Cheung, X.M. An, Y.C. Chen and M. Li et al., 2007. Cell cycle-related kinase: A novel candidate oncogene in human glioblastoma. J. Natl. Cancer Inst., 99: 936-948.
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  44. Wang, J., Y. Peng, Y.W. Sun, H. He and S. Zhu et al., 2006. All-trans retinoic acid induces XAF1 expression through an interferon regulatory factor-1 element in colon cancer. Gastroenterology, 130: 747-758.
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  45. Peng, Y., P.H. Yang, J.A. Tanner, J.D. Huang and M. Li et al., 2006. Cold-inducible RNA binding protein is required for the expression of adhesion molecules and embryonic cell movement in Xenopus laevis. Biochem. Biophys. Res. Commun., 344: 416-426.
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  46. Luo, C., Y. Peng, R. Santti, M.L. He and M.C. Lin, 2006. COX-1 and -2 expressions in vas deferens and prostate of neonatally estrogen treated aging rats and Hydroxymatairesinol for COX-2 inhibition assay. Endocrine, 29: 161-168.

  47. Li, X.P., C.Y. Li, X. Li, Y. Ding, L.L. Chan and P.H. Yang et al., 2006. Inhibition of human nasopharyngeal carcinoma growth and metastasis in mice by adenovirus-associated virus-mediated expression of human endostatin. Mol. Cancer Ther., 5: 1290-1298.
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  48. Li, X., X. Liu, C.Y. Li, Y. Ding and D. Chau et al., 2006. Recombinant adeno-associated virus mediated RNA interference inhibits metastasis of nasopharyngeal cancer cells in vivo and in vitro by suppression of Epstein-Barr virus encoded LMP-1. Int. J. Oncol., 29: 595-603.
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  49. Li, M., S.S. Ng, J. Wang, L. Lai and S.Y. Leung et al., 2006. EFA6A enhances glioma cell invasion through ADP ribosylation factor 6/extracellular signal-regulated kinase signaling. Cancer Res., 66: 1583-1590.
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  50. He, M.L., B.J. Zheng, Y. Chen, K.L. Wong and J.D. Huang et al., 2006. Kinetics and synergistic effects of siRNAs targeting structural and replicase genes of SARS-associated coronavirus. FEBS Lett., 580: 2414-2420.
    CrossRef  |  

  51. Qian, W.P., Y.Q. Tan, Y. Chen, Y. Peng and Z. Li et al., 2005. Rapid quantification of semen hepatitis B virus DNA by real-time polymerase chain reaction. World J. Gastroenterol., 11: 5385-5389.
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  52. Peng, Y., K.H. Kwok, P.H. Yang, S.S. Ng and J. Liu et al., 2005. Ascorbic acid inhibits ROS production, NF-ΚB activation and prevents ethanol-induced growth retardation and microencephaly. Neuropharmacology, 48: 426-434.
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  53. Zheng, B., M.L. He, K.L. Wong, C.T. Lum and L.L. Poon et al., 2004. Potent inhibition of SARS-associated coronavirus (SCOV) infection and replication by type I interferons (IFN-α/β) but not by type II interferon (IFN-γ). J. Interferon Cytokine Res., 24: 388-390.
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  54. Peng, Y., P.H. Yang, Y. Guo, S.S. Ng and J. Liu et al., 2004. Catalase and peroxiredoxin 5 protect xenopus embryos against alcohol-induced ocular anomalies. Invest. Ophthalmol. Visual Sci., 45: 23-29.
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  55. Peng, Y., P.H. Yang, S.S. Ng, O.G. Wong and J. Liu et al., 2004. A critical role of Pax6 in alcohol-induced fetal microcephaly. Neurobiol. Dis., 16: 370-376.
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  56. Peng, Y., P.H. Yang, S.S. Ng, C.T. Lum and H.F. Kung et al., 2004. Protection of Xenopus laevis embryos against alcohol-induced delayed gut maturation and growth retardation by peroxiredoxin 5 and catalase. J. Mol. Biol., 340: 819-827.
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  57. Peng, Y., B.H. Jiang, P.H. Yang, Z. Cao and X. Shi et al., 2004. Phosphatidylinositol 3-kinase signaling is involved in neurogenesis during Xenopus embryonic development. J. Biol. Chem., 279: 28509-28514.
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  58. Li, X.P., G. Li, Y. Peng, H.F. Kung and M.C. Lin, 2004. Suppression of Epstein-Barr virus-encoded latent membrane protein-1 by RNA interference inhibits the metastatic potential of nasopharyngeal carcinoma cells. Biochem. Biophys. Res. Commun., 315: 212-218.
    CrossRef  |  

  59. He, M.L., B. Zheng, Y. Peng, J.S. Peiris and L.L. Poon et al., 2003. Inhibition of SARS-associated coronavirus infection and replication by RNA interference. JAMA, 26: 2665-2666.
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  60. Deng, Y., L. Yao, L. Chau, S.S. Ng and Y. Peng et al., 2003. N-myc downstream-regulated gene 2 (NDRG2) inhibits glioblastoma cell proliferation. Int. J. Cancer, 106: 342-347.
    CrossRef  |  Direct Link  |  

  61. Wong, K., Y. Peng, H.F. Kung and M.L. He, 2002. Retina dorsal/ventral patterning by Xenopus TBx3. Biochem. Biophys. Res. Commun., 290: 737-742.
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  62. Peng, Y., R.H. Xu, J.M. Mei, X.P. Li, D. Yan, H.F. Kung and J.M. Phang, 2002. Neural inhibition by c-Jun as a synergizing factor in bone morphogenetic protein 4 signaling. Neuroscience, 109: 657-664.
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  63. He, M.L., Y. Chen, Y. Peng, D. Jin and D. Du et al., 2002. Induction of apoptosis and inhibition of cell growth by developmental regulator hTBX5. Biochem. Biophys. Res. Commun., 297: 185-192.
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  64. Xu, R.H., Y. Peng, J. Fan, D. Yan and S. Yamagoe et al., 2000. Histone acetylation is a checkpoint in FGF-stimulated mesoderm induction. Dev. Dyn., 218: 628-635.
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  65. Peng, Y., K.H. Kok, R.H. Xu, K.H. Kwok and D. Tay et al., 2000. Maternal cold inducible RNA binding protein is required for embryonic kidney formation in Xenopus laevis. FEBS Lett., 482: 37-43.
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  66. Liu, W., C. Ren, J. Shi, X. Feng and Z. He et al., 2000. Characterization of the functionally related sites in the neural inducing gene noggin. Biochem. Biophys. Res. Commun., 270: 293-297.
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  67. Xu, R.H., K.T. Ault, J. Kim, M.J. Park and Y.S. Hwang et al., 1999. Opposite effects of FGF and BMP-4 on embryonic blood formation: Roles of PV.1 and GATA-2. Dev. Biol., 208: 352-361.
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