Dr. Yanmin Zhang

Associate Professor
Xi`an Jiaotong University, China

Highest Degree
Ph.D. in Pharmaceutical Analysis from Xi'an Jiaotong University, China

My URL
https://livedna.org/86.6283

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Area of Interest:

Pharmacology and Toxicology
Tumor Pharmacology
Drug Process Analysis
Cell Biology
Phytomedicine

Selected Publications

  1. Zheng, L., X. Wang, W. Luo, Y. Zhan and Y. Zhang, 2013. Brucine, an effective natural compound derived from nux-vomica, induces G1 phase arrest and apoptosis in LoVo cells. Food Chem. Toxicol., 58: 332-339.
    CrossRef  |  Direct Link  |  

  2. Zhang, D., Y. Zhang, L. Zheng, Y. Zhan and L. He, 2013. Graphene oxide/poly-L-lysine assembled layer for adhesion and electrochemical impedance detection of leukemia K562 cancer cells. Biosensors Bioelectronics, 42: 112-118.
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  3. Zhang, D., Y. Zhang and L. He, 2013. Sensitive voltammetric determination of baicalein at thermally reduced graphene oxide modified glassy carbon electrode. Electroanalysis, 25: 2136-2144.
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  4. Zhan, Y., Y. Chen, R. Liu, H. Zhang and Y. Zhang, 2013. Potentiation of paclitaxel activity by curcumin in human breast cancer cell by modulating apoptosis and inhibiting EGFR signaling. Arch. Pharm. Res., 10.1007/s12272-013-0311-3.
    CrossRef  |  

  5. Wang, Y., N. Wang, L. Wu, W. Lu and Y. Zhang, 2013. Simultaneous determination of four components in Baige capsule by HPLC: Application to pharmacokinetics and tissue distribution of normal and middle cerebral artery occlusion rats. Biomed. Chromatography, 10.1002/bmc.3067.
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  6. Wang, N., Y. Zhang, L. Wu, Y. Wang and Y. Cao et al., 2013. Puerarin protected the brain from cerebral ischemia injury via astrocyte apoptosis inhibition. Neuropharmacology, 79: 282-289.
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  7. Wang, N., L. Zheng, Y. Zhan and Y. Zhang, 2013. A novel taspine derivative suppresses human liver tumor growth and invasion in vitro and in vivo. Oncol. Lett., 6: 855-859.
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  8. Wang, N., L. Wu, Y. Cao, Y. Wang and Y. Zhang, 2013. The protective activity of imperatorin in cultured neural cells exposed to hypoxia re-oxygenation injury via anti-apoptosis. Fitoterapia, 90: 38-43.
    CrossRef  |  

  9. Wang, C., J. Dong, Y. Zhang, F. Wang and H. Gao et al., 2013. Design, synthesis and biological evaluation of biphenyl urea derivatives as novel VEGFR-2 inhibitors. Med. Chem. Commun., 4: 1434-1438.
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  10. Pan, X., F. Wang, Y. Zhang, H. Gao, Z. Hu, S. Wang and J. Zhang, 2013. Design, synthesis and biological activities of Nilotinib derivates as antitumor agents. Bioorganic Med. Chem., 21: 2527-2534.
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  11. Niu, X., T. Fan, W. Li, H. Huang, Y. Zhang and W. Xing, 2013. Protective effect of sanguinarine against acetic acid-induced ulcerative colitis in mice. Toxicol. Applied Pharmacol., 267: 256-265.
    CrossRef  |  Direct Link  |  

  12. Luo, W., X. Wang, L. Zheng, Y. Zhan, D. Zhang, J. Zhang and Y. Zhang, 2013. Brucine suppresses colon cancer cells growth via mediating KDR signalling pathway. J. Cell. Mol. Med., 17: 1316-1324.
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  13. Li, W., T. Fan, Y. Zhang, T. Fan, P. Zhou, X. Niu and L. He, 2013. Houttuynia cordata Thunb. volatile oil exhibited anti-inflammatory effects in vivo and inhibited nitric oxide and tumor necrosis factor-a production in lps-stimulated mouse peritoneal macrophages in vitro. Phytotherapy Res., 27: 1629-1639.

  14. Zheng, L., X. He, W. Ma, B. Dai, Y. Zhan and Y. Zhang, 2012. Ta1722, an anti-angiogenesis inhibitor targeted on VEGFR-2 against human hepatoma. Biomed. Pharmacotherapy, 66: 499-505.
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  15. Zhang, Y.M., B.L. Dai, L. Zheng, Y.Z. Zhan and J. Zhang et al., 2012. A novel angiogenesis inhibitor impairs lovo cell survival via targeting against human VEGFR and its signaling pathway of phosphorylation. Cell Death Dis., Vol. 3. 10.1038/cddis.2012.145.
    CrossRef  |  

  16. Zhang, J., Y. Zhang, X. Pan, C. Wang, Z. Hu, S. Wang and L. He, 2012. Facile synthesis and biological evaluation of novel symmetrical biphenyls as antitumor agents. Med. Chem., 8: 145-150.
    CrossRef  |  

  17. Zhan, Y., Y. Zhang, C. Liu, J. Zhang and W.W. Smith et al., 2012. A novel taspine derivative, HMQ1611, inhibits breast cancer cell growth via estrogen receptor α and EGF receptor signaling pathways. Cancer Prevention Res., 5: 864-873.
    CrossRef  |  

  18. Lu, W., B. Dai, W. Ma and Y. Zhang, 2012. A novel taspine analog, HMQ1611, inhibits growth of non-small cell lung cancer by inhibiting angiogenesis. Oncol. Lett., 4: 1109-1113.
    CrossRef  |  

  19. Li, W., T. Fan, Y. Zhang, X. Niu and W. Xing, 2012. Effect of Chelerythrine against endotoxic shock in mice and its modulation of inflammatory mediators in peritoneal macrophages through the modulation of Mitogen-Activated Protein Kinase (MAPK) pathway. Inflammation, 35: 1814-1824.
    CrossRef  |  

  20. He, H.Z., N. Wang, J. Zhang, L. Zheng and Y.M. Zhang, 2012. Tas13D inhibits growth of SMMC-7721 cell via suppression VEGF and EGF expression. Asian Pac. J. Cancer Prev., 13: 2009-2014.
    Direct Link  |  

  21. He, H., Y. Zhan, Y. Zhang, J. Zhang and L. He, 2012. Synthesis of novel taspine diphenyl derivatives as fluorescence probes and inhibitors of breast cancer cell proliferation. Luminescence, 27: 310-314.
    CrossRef  |  

  22. Zhang, Y., Q. Jiang, N. Wang, B. Dai, Y. Chen and L. He, 2011. Effects of taspine on proliferation and apoptosis by regulating caspase-3 expression and the ratio of Bax/Bcl-2 in A431 cells. Phytotherapy Res., 25: 357-364.
    CrossRef  |  

  23. Zhang, Y., L. Zheng, J. Zhang, B. Dai, N. Wang, Y. Chen and L. He, 2011. Anti-tumor activity of taspine by modulating EGFR signaling pathway of Erk1/2 and Akt in vitro and in vivo. Planta Med., 77: 1774-1781.
    CrossRef  |  

  24. Zhang, Y., J. Zhang, B. Dai, N. Wang and L. He, 2011. Anti-proliferative and apoptotic effects of the novel taspine derivative tas41 in the Caco-2 cell line. Environm. Toxicol. Pharmacol., 31: 406-415.
    CrossRef  |  

  25. Zhang, J., Y. Zhang, X. Pan, S. Wang and L. He, 2011. Synthesis and cytotoxic evaluation of novel symmetrical taspine derivatives as anticancer agents. Med. Chem., 7: 286-294.
    CrossRef  |  

  26. Zhan, Y., Y. Zhang, Y. Chen, N. Wang, L. Zheng and L. He, 2011. Activity of taspine isolated from Radix et Rhizoma Leonticis against estrogen-receptor-positive breast cancer. Fitoterapia, 82: 896-902.
    CrossRef  |  

  27. Zhan, Y., M. Sun, Y. Chen and Y. Zhang, 2011. Determination of taspine using HPLC-MS and its effect on EGFR in A431 and HEK293/EGFR cells. Chromatographia, 74: 383-389.
    CrossRef  |  

  28. Li, W., P. Zhou, Y. Zhang and L. He, 2011. Houttuynia cordata, a novel and selective COX-2 inhibitor with anti-inflammatory activity. J. Ethnopharmacol., 133: 922-927.
    CrossRef  |  

  29. Zhou, Y., W. Luo, L. Zheng, M. Li and Y. Zhang, 2010. Construction of recombinant FGFR1 containing full-length gene and its potential application. Plasmid, 64: 60-67.
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  30. Zhang, Y., Y. Qu, J. Zhang and X. Wang, 2010. Ardipusilloside I purified from Ardisia pusilla competitively binds VEGFR and induces apoptosis in NCI-H460 cells. Phytomedicine, 17: 519-526.
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  31. Zhang, J., Y. Zhang, Y. Shan, N. Li, W. Ma and L. He, 2010. Synthesis and preliminary biological evaluation of novel taspine derivatives as anticancer agents. Eur. J. Med. Chem., 45: 2798-2805.
    CrossRef  |  

  32. Zhang, J., Y. Zhang, S. Zhang, S. Wang and L. He, 2010. Discovery of novel taspine derivatives as antiangiogenic agents. Bioorganic Med. Chem. Lett., 20: 718-721.
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  33. Wang, S., S. Meng, Y. Zhang, H. Du and L. He, 2010. A new A431/CMC-online-HPLC/MS method for screening anti-EGFR antagonists from Radix Sophorae Flavescentis. J. Chromatography A, 1217: 5246-5252.

  34. Wang, S., M. Sun, Y. Zhang, J. Zhang and L. He, 2010. EGFR/cell membrane chromatography-online-high performance liquid chromatography/mass spectrometry method for screening EGFR antagonists from Radix Angelicae Pubescentis. Sci. China-Chem., 53: 2357-2362.
    CrossRef  |  

  35. Sun, M., J. Ren, H. Du, Y. Zhang, J. Zhang, S. Wang and L. He, 2010. A combined A431 cell membrane chromatography and online high performance liquid chromatography/mass spectrometry method for screening compounds from total alkaloid of Radix Caulophylli acting on the human EGFR. J. Chromatography B, 878: 2712-2718.
    CrossRef  |  

  36. Li, M., S. Wang, Y. Zhang and L. He, 2010. An online coupled cell membrane chromatography with LC/MS method for screening compounds from Aconitum carmichaeli Debx. acting on VEGFR-2. J. Pharm. Biomed. Anal., 53: 1063-1069.
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  37. Zhang, Y., L. He, L. Meng, W. Luo and X. Xu, 2008. Suppression of tumor-induced angiogenesis by taspine isolated fromRadix et Rhizoma Leonticis and its mechanism of action in vitro. Cancer Lett., 262: 103-113.
    CrossRef  |  

  38. Zhang, Y., L. He, L. Meng and W. Luo, 2008. Taspine isolated from Radix et Rhizoma Leonticis inhibits proliferation and migration of endothelial cells as well as chicken chorioallantoic membrane neovascularisation. Vascular Pharmacol., 48: 129-137.
    CrossRef  |  

  39. Zhang, Y., L. He and Y. Zhou, 2008. Taspine isolated from Radix et Rhizoma Leonticis inhibits growth of human umbilical vein endothelial cell (HUVEC) by inducing its apoptosis. Phytomedicine, 15: 112-119.
    CrossRef  |  
Member since January, 2014