Dr. Jin Zhang

Research Scientist
Department of Surgical and Radiological Sciences, University of California, USA


Highest Degree
Ph.D. in Genetics from Fudan University, Shanghai, China

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Area of Interest:

Molecular Sciences
Cancer Research
Molecular Cell Biology
Pathology
Chemical Compounds

Selected Publications

  1. Zhang, J., X. Chen, M.S. Kent, C.O. Rodriguez and X. Chen, 2009. Establishment of a dog model for the p53 family pathway and identification of a novel isoform of p21 cyclin-dependent kinase inhibitor. Mol. Cancer Res., 7: 67-78.
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  2. Scoumanne, A., J. Zhang and X. Chen, 2009. PRMT5 is required for cell-cycle progression and p53 tumor suppressor function. Nucl. Acid Res., 37: 4965-4976.
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  3. Zhang, J. and X. Chen, 2008. Posttranscriptional regulation of p53 and Its Targets by RNAbinding proteins. Curr. Mol. Med., 8: 845-849.
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  4. Qian, Y., J. Zhang, B. Yan and X. Chen, 2008. Dec1, a basic helix-loop-helix transcription factor and a novel target gene of the p53 family, mediates p53-dependent premature senescence. J. Biol. Chem., 283: 2896-2905.
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  5. Zhang, J. and X. Chen, 2007. The P53 family: Prospect for cancer gene therapy. Cancer Biol. Therapy, 6: 116-118.
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  6. Zhang, J. and X. Chen, 2007. ΔNp73 modulates nerve growth factor-mediated neuronal differentiation through repression of TrkA. Mol. Cell. Biol., 27: 3868-3880.
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  7. Xu, Y., J. Zhang and X. Chen, 2007. The activity of p53 is differentially regulated by Brm- and Brg1-containing SWI/SNF chromatin remodeling complexes. J. Biol. Chem., 282: 37429-37435.
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  8. Helton, S.E., J. Zhang and X. Chen, 2007. The proline-rich domain in p63 is necessary for the transcriptional and apoptosis-inducing activities of TAp63. Oncogene, 27: 2843-2850.
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  9. Geng, Y., R.S. Akhtar, J.J. Shacka, B.J. Klocke, J. Zhang, X. Chen and K.A. Roth, 2007. p53 transcription-dependent and -independent regulation of cerebellar neural precursor cell apoptosis. J. Neuropathol. Exp. Neurol., 66: 66-74.
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  10. Zhang, J., W. Yan and X. Chen, 2006. p53 is required for Nerve growth factor-mediated differentiation of PC12 cells via regulation of TrkA levels. Cell Death Differentiation, 12: 2118-2128.
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  11. Cai, X.P., J. Zhang and Y.Y. Li, 2005. Secretory expression of heterologous protein in Kluyveromyces cicerisporus. Applied Microbiol. Biotechnol., 67: 364-369.
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  12. Zhang, J., H. Yuan, T. Wen, F. Xu, Y. Di, R. Huo and Y.Y. Li, 2003. Cloning of the KcURA3 gene and development of a transformation system for Kluyveromyces cicerisporus. Applied Microbiol. Biotechnol., 62: 387-391.
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