Dr. Mohammad Nasir Uddin
Assistant ProfessorTexas A&M Health Science Center, USA
Highest Degree
Ph.D. in Biochemistry and Molecular Biology from Gifu University, Japan
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Area of Interest:
Selected Publications
- Uddin, M.N., S. Allen, R. Jones, D.C. Zawieja and T.J. Kuehl, 2011. Marinobufagenin and angiogenic imbalance are the indicators of cerebral vascular leak syndrome in preeclampsia. J. Investi. Med., 59: 692-730.
PubMed | - Munshi, M.K., M.N. Uddin and S.S. Glaser, 2011. The role of the renin-angiotensin system in liver fibrosis. Exp. Biol. Med., 236: 557-566.
PubMed | - Agunanne, E., D. Horvat, R. Harrison, M.N. Uddin and R. Jones et al., 2011. Marinobufagenin levels in preeclamptic patients: A preliminary report. Am. J. Pernitol., 28: 509-514.
PubMed | - Abi-Ghanem, D., L.R. Berghman, D. Romo, X. Lai and J. Li et al., 2011. A chemifluorescent immunoassay for the determination of marinobufagenin in body fluids. J. Immunoassay Immunochemistry, 32: 31-46.
PubMed | - Uddin, M.N., E. Agunanne, D. Horvat and J.B. Puschett, 2010. Alterations in the Renin-Angiotensin system in a rat model of human preeclampsia. Am. J. Nephrol., 31: 171-177.
CrossRef | Direct Link | - Puschett, J.B., E.E. Agunanne and M.N. Uddin, 2010. Emerging role of the bufodienolides in cardiovascular and renal disease. Am. J. Kidney Dis., 56: 359-370.
PubMed | - Nabi, A.N., K.B. Biswas, Y. Arai, M.N. Uddin and T. Nakagawa et al., 2010. Functional characterization of the decoy peptide, [R10P]IFLKRMPSI[19P]. Front Biosci., 2: 1211-1217.
PubMed | - Nabi, A.H.M.N., K.B. Biswas, Y. Arai, M.N. Uddin and T. Nakagawa et al., 2010. Functional characterization of the decoy peptide, R10piflkrmpsi. Front Biosci., 2: 1211-1217.
- Agunanne, E.E., M.N. Uddin, D. Horvat and J.B. Puschett, 2010. Contribution of angiogenic factors in a rat model of Pre-eclampsia. Am. J. Nephrol., 32: 332-339.
CrossRef | Direct Link | - Agunanne, A., M.N. Uddin, D. Horvat and J.B. Puschett, 2010. An analysis of the role of angiogenic factors in a rat model of preeclampsia. Am. J. Nephrol., 32: 332-339.
- Puschett, J.B., E.E. Agunanne and M.N. Uddin, 2010. Marinobufagenin, resibufagenin and preeclampsia. Biochim. Biophys. Acta. Mol. Basis Dis., 10.1016/j.bbadis.2010.02.005.
CrossRef | - Uddin, M.N., L.B. McLean, F.A. Hunter, D. Horvat and J. Severson et al., 2009. Vascular leak in a rat model of preeclampsia. Am. J. Nephrol., 30: 26-33.
CrossRef | Direct Link | - Uddin, M.N., E.W. Childs, D. Horvat and J.B. Puschett, 2009. Marinobufagenin enhances endothelial permeability via activation of apoptotic signaling. Am. J. Physiol. Regul. Integr. Comp. Physiol., 296: R1726-R1734.
CrossRef | Direct Link | - Uddin, M.N., E. Agunanne, D. Horvat and J. Puschett, 2009. Marinobufagenin causes enhanced permeability in human brain microvascular endothelial cells via apoptotic signaling. J. Am. Soc. Nephrol., 20: 534-535.
- Horvat, D., M.N. Uddin, B. Mitchel, J. Severson and J.B. Puschett, 2009. Resibufogenin prevents the manifestations of preeclampsia in an animal model of the syndrome. Hypertension Pregnancy, 10.1080/10641950802629709.
CrossRef | Direct Link | - Aggunanne, E., D. Horvat, M.N. Uddin and J.B. Puschett, 2009. The treatment of preeclampsia in a rat model employing digibind. Am. J. Perinatol., 27: 299-305.
PubMed | - Uddin, M.N., D. Horva, S. Glaser, S. Danchuk and B.M. Mitchell et al., 2008. Marinobufagenin inhibits proliferation and migration of cytotrophoblast and CHO cells. Placenta, 29: 266-273.
PubMed | - Uddin, M.N., D. Horva, S. Glaser, B.M. Mitchell and J.B. Puschett, 2008. Examination of the cellular mechanism by which marinobufagenin inhibits cytotrophoblast function. J. Biol. Chem., 283: 17946-17953.
- Uddin, M.N., A.H.M.N. Nabi, T. Nakagawa, A. Ichihara, T. Inagami and F. Suzuki, 2008. Non-proteolytic activation of prorenin: Aactivation by (pro)renin receptor and its inhibition by a prorenin prosegment, decoy peptide. Front. Biosci., 13: 745-753.
PubMed | - Sultana, A., A.H.M.N. Nabi, U.M. Nasir, H, Maruyama, K.M. Suzuki, S. Mishima and F. Suzuki, 2008. A dipeptide YY derived from royal jelly proteins inhibit renin activity. Int. J. Mol. Med., 21: 677-681.
PubMed | - Danchuk, S., S. Sukhanov, D. Horvat, M.N. Uddin and J.B. Puschett, 2008. Effects of resibufogenin in experimental hypertension. Am. J. Nephrol., 28: 8-13.
CrossRef | Direct Link | - Nabi, A.H.M.N., M.U. Nasir, M.N. Uddin, T. Nakagawa and H. Iwata et al., 2007. Biochemical and enzymatic properties of prorenin: Role of the `handle` peptide of the prosegment sequence in the binding and activation of prorenin molecule in recepto associated prorenin system. Frontiers Biosci., 12: 4810-4817.
- Kaneshiro, Y., A. Ichihara, T. Takemitsu, M. Sakoda and A.H.M.N. Nabi et al., 2007. Slowly progressive, angiotensin II- Independent glomerulosclerosis in human (Pro)renin-Receptor-transgenic rats. J. Am. Soc. Nephrol., 18: 1789-1795.
CrossRef | Direct Link | - Hayashi, T., O. Urayama, M. Hori, S. Sakamoto and U.M. Nasir et al., 2007. Laughter modulates prorenin receptor gene expression in patients with type 2 diabetes. J. Psychosom. Res., 62: 703-706.
CrossRef | Direct Link | - Uddin, M.N., B.A. Shibib, A.U. Mohamad, T. Tazib and R. Ahsan et al., 2006. Changes in physiological properties of soybean oil under various conditions. Bangladesh J. Med. Sci., 12: 28-34.
- Uddin, M.N., A.U. Mohamad, H.B. Shozib, T. Tazib and N. Masum et al., 2006. Evaluation of Prostate-specific antigen levels in sera of patients with prostate diseases using Enzyme-linked immunosorbent assay. Bangladesh J. Med. Sci., 12: 98-102.
- Nurun Nabi, A.H.M., A. Kageshima, M.N. Uddin, T. Nakagawa, E.Y. Park and F. Suzuki, 2006. Binding properties of rat prorenin and rennin to the recombinant rat renin/prorenin receptor prepared by a baculovirus expression system. Int. J. Mol. Med., 18: 483-488.
Direct Link | - Mohamad, A.U., M.N. Uddin, B.A. Shibib, T. Tazib and R. Ahsan et al., 2006. Quantitative assesment of serum alpha-fetoprotein among patients with liver diseases using a solid phase enzyme-linked immunosorbent assay. Bangladesh J. Med. Sci., 12: 20-23.
- Uddin, M.N., A.U. Mohamad, T. Tazib, R. Ahsan, J. Shafiq, N. Masum and B.A. Shibib, 2005. Diabetes Mellitus and its complications using Glycosylated Hemoglobin (HbA1c) and others related biochemical parameters. Bangladesh J. Med. Sci., 11: 112-115.
- Uddin, M.N. and S.A.M. Khairul Bashar, 2005. Studies on plasma prorenin, rennin and angiotensinogen concentrations in Bangladeshi patients with type 2 diabetes. Bangladesh J. Med. Sci., 11: 33-36.
- Shibib, B.A., M.N. Uddin, J. Shafiq and A.U. Mohamad, 2005. Effect of Coccinia indica extract on blood glucose, free fatty acid and hepatic phosphofructokinase-1 of both normal and diabetic rats. Bangladesh J. Med. Sci., 11: 106-111.
- Nasir, U.M., M.N. Uddin, S. Iwanaga, A.H.M. Nurun Nabi and O. Urayama et al., 2005. Laughter therapy modulates the parameters of renin-angiotensin system in patients with type 2 diabetes. Int. J. Mol. Med., 16: 1077-1681.
Direct Link | - Nabi, A.H.M.N., M.N. Uddin, T. Nakagawa, T. Orihashi, A. Ebihara, Y. Nakamura and F. Suzuki, 2005. Roles of His 9 (P2 subsite) and His13 (P3' subsite) in angiotensinogen for catalytic reaction of renin. Int. J. Mol. Med., 16: 103-107.
- Mohamad, A.U., T. Tazib, R. Ahsan, K. Aktar, T. Shirin, B.A. Shibib and M.N. Uddin, 2005. Level of triiodothyronine, thyroxine and thyroid stimulating hormone in sera of patients with thyroidism in Bangladesh. Bangladesh J. Med. Sci., 11: 101-105.
- Khatry, N., J. Kundu, S.C. Bacher, M.N. Uddin and J.K. Kundu, 2005. Studies on antinociceptive, anti-inflammatory and diuretic activities of methanol extract of the aerial parts of Clerodendron viscosum Vent. Dhaka Univ. J. Pharm. Sci., 5: 63-66.
- Ahsan, R., A.U. Mohamad, T. Tazib, B.A. Shibib, J. Shafiq and M.N. Uddin, 2005. Biochemical parameters related to kidney diseases in Bangladeshi patients. Bangladesh J. Med. Sci., 11: 121-126.
- Ichihara, A., M. Hayashi, Y. kaneshiro, F. Suzuki and T. Nakagawa et al., 2004. Inhibition of diabetic nephropathy by a decoy peptide corresponding to the handle region for non-proteolytic activation of prorenin. J. Clin. Invest., 114: 1128-1135.
CrossRef | Direct Link | - Suzuki, F., M. Hayakawa, T. Nakagawa, U.M. Nasir and M.N. Uddin et al., 2003. Human prorenin has the regions of gate and handle for its non-proteolytic activation.. Biol. Chem., 278: 22217-22222.
- Uddin, M.N. and S.N. Shahed, 2002. Purification and characterization of human renin and sheep angiotensinogen. Bangladesh J. Med. Sci., 8: 84-88.
- Rahman, S.M., M.N. Huda, M.N. Uddin and S. Akhtaruzzaman, 2002. Shortterm administration of Conjugated Linoleic acid reduces liver triglyceride concentration and phosphatidate phosphohydrolase activity in OLETF rats. J. Biochem. Mol. Biol., 35: 494-497.
- Shahed, S.N. and M.N. Uddin, 2001. Kinetic properties of recombinant human phenyl-ethanolamine-N-methyltransferase produced in Escherichia coli. Bangladesh J. Med. Sci., 7: 79-83.
- Ebihara, A., U.M. Nasir, M.N. Uddin, S. Yoshida and T. Kondou et al., 2000. Sialic acid residue of ovine angiotensinogen does not affect the reactivity to human renin. Biomed. Res., 21: 105-109.
- Ebihara, A., T. Kondou, S. Mizuno, T. Nakagawa and U.M. Nasir et al., 2000. Molecular properties of recombinant ovine angiotensinogen. Biomed. Res., 21: 247-254.