Dr. Hsin-Chen Lee

Research Scientist
National Yang-Ming University, Taiwan


Highest Degree
Ph.D. in Biochemistry from National Yang-Ming University, Taipei, Taiwan

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Area of Interest:

Molecular Sciences
Biochemistry
Cell Biology
Oxidative Stress
Cancer

Selected Publications

  1. Yin, P.H., C.C. Wu, J.C. Lin, C.W. Chi, Y.H. Wei and H.C. Lee, 2010. Somatic mutations of mitochondrial genome in hepatocellular carcinoma. Mitochondrion, 10: 174-182.
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  2. Lee, H.C., C.M. Chang and C.W. Chi, 2010. Somatic mutations of mitochondrial DNA in aging and cancer progression. Ageing Res. Rev., 9: S47-S58.
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  3. Hung, W.Y., C.W. Wu, P.H. Yin, C.J. Chang and A.F.Y. Li et al., 2010. Somatic mutations in mitochondrial genome and their potential roles in the progression of human gastric cancer. Biochim. Biophys. Acta (BBA)-Gen. Subjects, 1800: 264-270.
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  4. Chang, C.J., P.H. Yin, D.M. Yang, C.H. Wang and W.Y. Hung et al., 2009. Mitochondrial dysfunction-induced amphiregulin upregulation mediates chemo-resistance and cell migration in HepG2 cells. Cell. Mol. Life Sci., 66: 1755-1765.
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  5. Wang, S.F., J.C. Yen, P.H. Yin, C.W. Chi and H.C. Lee, 2008. Involvement of oxidative stress-activated JNK signaling in the methamphetamine-induced cell death of human SH-SY5Y cells. Toxicology, 246: 234-241.
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  6. Hung, W.Y., J.C. Lin, L.M. Lee, C.W. Wu and L.M. Tseng et al., 2008. Tandem duplication/triplication correlated with poly-cytosine stretch variation in human mitochondrial DNA D-loop region. Mutagenesis, 23: 137-142.
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  7. Wu, C.W., Y.H. Ping, J.C. Yen, C.Y. Chang and S.F. Wang et al., 2007. Enhanced oxidative stress and aberrant mitochondrial biogenesis in human neuroblastoma SH-SY5Y cells during methamphetamine induced apoptosis. Toxicol. Applied Pharmacol., 220: 243-251.
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  8. Lee, H.C., L.S. Hsu, P.H. Yin, L.M. Lee and C.W. Chi, 2007. Heteroplasmic mutation of mitochondrial DNA D-loop and 4977-bp deletion in human cancer cells during mitochondrial DNA depletion. Mitochondrion, 7: 157-163.
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