Dr. Hui Fen Liao

Professor
National Chiayi University, Taiwan

Highest Degree
Ph.D. in Medicine from National Yang-Ming University, Taipei, Taiwan

My URL
https://livedna.org/886.23336

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Area of Interest:

Biomedical Sciences
Medicine
Traditional Medicine
Oral Cancer
Chemotherapeutic Agents

Selected Publications

  1. Liu, C.K., C.A. Chen, T.Y. Lee, H.H. Chang, H.F. Liao and Y.J. Chen, 2018. Rice protein prolamin promotes anti-leukemia immunity and inhibits leukemia growth in vivo. Food Chem. Toxicol., 112: 435-440.
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  2. Yu, C.C., S.K. Hung, H.Y. Lin, W.Y. Chiou and M.S. Lee et al., 2017. Targeting the PI3K/AKT/mTOR signaling pathway as an effectively radiosensitizing strategy for treating human oral squamous cell carcinoma in vitro and in vivo. Oncotarget, 8: 68641-68653.
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  3. Yu, C.C., H.B. Huang, S.K. Hung, H.F. Liao and C.C. Lee et al., 2016. AZD2014 radiosensitizes oral squamous cell carcinoma by inhibiting AKT/mTOR axis and inducing G1/G2/M cell cycle arrest. PLoS ONE, Vol. 11. 10.1371/journal.pone.0151942.
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  4. Huang, Y.T., H.F. Liao, S.L. Wang and S.Y. Lin, 2016. Glycation and secondary conformational changes of human serum albumin: Study of the FTIR spectroscopic curve-fitting technique. Biophysics, 3: 247-260.
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  5. Chang, M.C., J.Y. Wu, H.F. Liao, Y.J. Chen and C.D. Kuo, 2016. Comparative assessment of therapeutic safety of norcantharidin, N-farnesyloxy-norcantharimide and N-farnesyl-norcantharimide against Jurkat T cells relative to human normal lymphoblast: A quantitative pilot study. Medicine, Vol. 95, No. 31. 10.1097/MD.0000000000004467.
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  6. Liao, H.F., T.J. Wu, J.L. Tai, M.C. Chi and L.L. Lin, 2015. Immunomodulatory potential of the polysaccharide-rich extract from edible cyanobacterium Nostoc commune. Med. Sci., 3: 112-123.
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  7. Chang, M.C., J.Y. Wu, H.F. Liao, Y.J. Chen and C.D. Kuo, 2015. N-Farnesyloxy-norcantharimide inhibits progression of human leukemic Jurkat T cells through regulation of mitogen-activated protein kinase and interleukin-2 production. Anti-Cancer Drugs, 26: 1034-1042.
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  8. Chang, M.C., E.T. Tsai, J.Y. Wu, H.F. Liao, Y.J. Chen and C.D. Kuo, 2015. N-Farnesyloxy-norcantharimide and N-farnesyl-norcantharimide inhibit the progression of leukemia and increase survival days in a syngeneic mouse leukemia model. Anti-Cancer Drugs, 26: 508-517.
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  9. Yu, C.C., S.K. Hung, H.F. Liao, C.C. Lee and H.Y. Lin et al., 2014. RAD001 enhances the radiosensitivity of SCC4 oral cancer cells by inducing cell cycle arrest at the G2/M checkpoint. Anticancer Res., 34: 2927-2935.
    PubMed  |  Direct Link  |  

  10. Wu, J.Y., C.D. Kuo, C.Y. Chu, M.S. Chen, J.H. Lin, Y.J. Chen and H.F. Liao, 2014. Synthesis of novel lipophilic N-substituted norcantharimide derivatives and evaluation of their anticancer activities. Molecules, 19: 6911-6928.
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  11. Lee, T.H., C.C. Chen, J.J. Chen, H.F. Liao and H.S. Chang et al., 2014. New and cytotoxic components from Antrodia camphorata. Molecules, 19: 21378-21385.
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  12. Chen, Y.J., Y.C. Huang, T.H. Tsai and H.F. Liao, 2014. Effect of wasabi component 6-(methylsulfinyl)hexyl isothiocyanate and derivatives on human pancreatic cancer cells. Evidence-Based Complement. Altern. Med. 10.1155/2014/494739.
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  13. Su, Y.C., S.C. Li, Y.C. Wu, L.M. Wang, K.S. Chao and H.F. Liao, 2013. Resveratrol downregulates interleukin-6-stimulated sonic hedgehog signaling in human acute myeloid leukemia. Evidence-Based Complement. Altern. Med., Vol. 2013. 10.1155/2013/547430.
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  14. Su, Y.C., S.C. Li, H.Y. Peng, Y.H. Ho, L.J. Chen and H.F. Liao, 2013. RAD001-mediated STAT3 upregulation and megakaryocytic differentiation. Thrombosis Haemostasis, 109: 540-549.
    CrossRef  |  PubMed  |  Direct Link  |  

  15. Liao, H.F., K.C. Chao, Y.J. Chen and M.S. Chang, 2013. Complementary and alternative medicine in cancer stem cells. Evidence-Based Complement. Altern. Med., Vol. 2013. 10.1155/2013/560274.
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  16. Huang, Y.C., K.S. Chao, H.F. Liao and Y.J. Chen, 2013. Targeting sonic hedgehog signaling by compounds and derivatives from natural products. Evidence-Based Complement. Altern. Med., Vol. 2013. 10.1155/2013/748587.
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  17. Hsieh, C.H., K.S. Chao, H.F. Liao and Y.J. Chen, 2013. Norcantharidin, derivative of cantharidin, for cancer stem cells. Evidence-Based Complement. Altern. Med., Vol. 2013. 10.1155/2013/838651.
    CrossRef  |  Direct Link  |  

  18. Chen, Y.J., Y.Y. Chen, Y.F. Lin, H.Y. Hu and H.F. Liao, 2013. Resveratrol inhibits alpha-melanocyte-stimulating hormone signaling, viability and invasiveness in melanoma cells. Evidence-Based Complement. Altern. Med., Vol. 2013. 10.1155/2013/632121.
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  19. Su, Y.C., S.C. Li, C.K. Hsu, C.C. Yu, T.J. Lin, C.Y. Lee and H.F. Liao, 2012. G-CSF downregulates natural killer cell-mediated cytotoxicity in donors for hematopoietic SCT. Bone Marrow Transplant., 47: 73-81.
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  20. Liu, C.Y., T.H. Tsai, Y.C. Huang, H.R. Shieh, H.F. Liao and Y.J. Chen, 2012. Differential immunomodulating effects of pegylated liposomal doxorubicin nanoparticles on human macrophages. J. Nanosci. Nanotechnol., 12: 7739-7746.
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  21. Liao, H.F., Y.C. Su, Z.Y. Zheng, C.J. Cai, M.H. Hou, K.C. Chao and Y.J. Chen, 2012. Sonic hedgehog signaling regulates Bcr-Abl expression in human chronic myeloid leukemia cells. Biomed. Pharmacother., 66: 378-383.
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  22. Liao, H.F., C.H. Kao, W.D. Lin, N.W. Hsiao, W.H. Hsu and Y.C. Lee, 2012. N-Acetyl-D-glucosamine 2-epimerase from Anabaena sp. CH1 contains a novel ATP-binding site required for catalytic activity. Process Biochem., 47: 948-952.
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  23. Liao, H.F., A.J. Cheng, H.T. Huang, M.L. Shen, T.K. Hei and Y.J. Chen, 2012. Nuclear factor-κB as a switch in regulation of resveratrol-mediated apoptosis and erythrocytic differentiation in human leukaemia cells. Food Chem., 132: 2094-2101.
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  24. Chiang, M.F., S.T. Yeh, H.F. Liao, N.S. Chang and Y.J. Chen, 2012. Overexpression of WW domain-containing oxidoreductase WOX1 preferentially induces apoptosis in human glioblastoma cells harboring mutant p53. Biomed. Pharmacother., 66: 433-438.
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  25. Chen, Y.Y., C.M. Jiang, S.H. Wang, M.K. Shih, H.Y. Hu and H.F. Liao, 2012. The anti-leukemic lectins from Canavalia ensiformis induce macrophage differentiationthrough cross-regulation between monocytes and lymphocytes. J. Med. Plants Res., 6: 534-543.
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  26. Chen, Y.J., C.D. Kuo, S.H. Chen, W.J. Chen, W.C. Huang, K.C. Chao and H.F. Liao, 2012. Small-molecule synthetic compound norcantharidin reverses multi-drug resistance by regulating Sonic hedgehog signaling in human breast cancer cells. PLoS ONE, Vol. 7. 10.1371/journal.pone.0037006.
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  27. Peng, H.Y. and H.F. Liao, 2011. Staurosporine induces megakaryocytic differentiation through the upregulation of JAK/Stat3 signaling pathway. Ann. Hematol., 90: 1017-1029.
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Member since February, 2018