Dr. Chan-Yen Kuo

Assistant Professor
Department of Research, Taipei Tzuchi Hospital, The Buddhist Tzuchi Medical Foundation, New Taipei City, Taiwan

Highest Degree
Ph.D. in Life Science from Tunghai University, Taiwan

My URL
https://livedna.org/886.27913

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Area of Interest:

Biomedical Sciences
Cancer Research
Immunology
Molecular Biology
Cell and Tumor Biology

Selected Publications

  1. Yeh, Y.H., C.Y. Liang, M.L. Chen, F.M. Tsai and Y.Y. Lin et al., 2019. Apoptotic effects of hsian‐tsao (Mesona procumbens Hemsley) on hepatic stellate cells mediated by reactive oxygen species and ERK, JNK and caspase‐3 pathways. Food Sci. Nutr., 7: 1891-1898.
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  2. Hsu, C.P., C.H. Lin and C.Y. Kuo, 2019. Endothelial-cell inflammation and damage by reactive oxygen species are prevented by propofol via ABCA1-mediated cholesterol efflux. Int. J. Med. Sci., 15: 978-985.
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  3. Shao, Y.C., J.C. Liou, C.Y. Kuo, Y.S. Tsai and E.C. Lin et al., 2017. UVB promotes the initiation of uveitic inflammatory injury in vivo and is attenuated by UV-blocking protection. Mol. Vision, 23: 219-227.
    PubMed  |  Direct Link  |  

  4. Kuo, C.Y., C.H. Lin and T. Hsu, 2017. VHL inactivation in precancerous kidney cells induces an inflammatory response via ER stress-activated IRE1α signaling. Cancer Res., 77: 3406-3416.
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  5. Chen, C.C., C.Y. Kuo and R.F. Chen, 2016. Role of CAPE on cardiomyocyte protection via connexin 43 regulation under hypoxia. Int. J. Med. Sci., 13: 754-758.
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  6. Kuo, C.Y., Y.C. Chiu, A.Y.L. Lee and T.L. Hwang, 2015. Mitochondrial Lon protease controls ROS-dependent apoptosis in cardiomyocyte under hypoxia. Mitochondrion, 23: 7-16.
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  7. Kao, T.Y., Y.C. Chiu, W.C. Fang, C.W. Cheng and C.Y. Kuo et al., 2015. Mitochondrial Lon regulates apoptosis through the association with Hsp60-mtHsp70 complex. Cell Death Dis., Vol. 6, No. 2. 10.1038/cddis.2015.9.
    CrossRef  |  Direct Link  |  

  8. Kuo, L.M., C.Y. Kuo, C.Y. Lin, M.F. Hung, J.J. Shen and T.L. Hwang, 2014. Intracellular glutathione depletion by oridonin leads to apoptosis in hepatic stellate cells. Molecules, 19: 3327-3344.
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  9. Yang, S.C., P.J. Chung, C.M. Ho, C.Y. Kuo and M.F. Hung et al., 2013. Propofol inhibits superoxide production, elastase release and chemotaxis in formyl peptide-activated human neutrophils by blocking formyl peptide receptor 1. J. Immunol., 190: 6511-6519.
    CrossRef  |  Direct Link  |  

  10. Kuo, C.Y., T.Y. Chou, C.M. Chen, G.Y. Hwang and T.L. Hwang, 2013. Hepatitis B virus X protein disrupts stress fiber formation and triggers apoptosis. Virus Res., 175: 20-29.
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  11. Cheng, C.W., C.Y. Kuo, C.C. Fan, W.C. Fang and S.S. Jiang et al., 2013. Overexpression of Lon contributes to survival and aggressive phenotype of cancer cells through mitochondrial complex I-mediated generation of reactive oxygen species. Cell Death Dis., Vol. 4, No. 6. 10.1038/cddis.2013.204.
    CrossRef  |  Direct Link  |  

  12. Cheng, A.N., S.S. Jiang, C.C. Fan, Y.K. Lo and C.Y. Kuo et al., 2013. Increased Cdc7 expression is a marker of oral squamous cell carcinoma and overexpression of Cdc7 contributes to the resistance to DNA-damaging agents. Cancer Lett., 337: 218-225.
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  13. Lee, P.H., S.H. Tsai, L. Kuo, C.Y. Hwang, C.Y. Kuo, V.C. Yang and J.K. Chen, 2012. A prototype tissue engineered blood vessel using amniotic membrane as scaffold. Acta Biomater., 8: 3342-3348.
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  14. Kuo, C.Y., J.I. Tsai, T.Y. Chou, M.J. Hung, C.C. Wu, S.L. Hsu and G.Y. Hwang, 2012. Apoptosis induced by hepatitis B virus X protein in a CCL13-HBx stable cell line. Oncol. Rep., 28: 127-132.
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  15. Ho, H.C., H.C. Chang, C.T. Ting, C.Y. Kuo and V.C. Yang, 2012. Caffeic acid phenethyl ester inhibits proliferation and migration and induces apoptosis in platelet-derived growth factor-BB-stimulated human coronary smooth muscle cells. J. Vasc. Res., 49: 24-32.
    CrossRef  |  Direct Link  |  

  16. Kuo, C.Y., Y.C. Lin, J.J. Yang and V.C. Yang, 2011. Interaction abolishment between mutant caveolin-1Δ62-100 and ABCA1 reduces HDL-mediated cellular cholesterol efflux. Biochem. Biophys. Res. Commun., 414: 337-343.
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  17. Lin, Y.C., C.H. Lin, C.Y. Kuo and V.C. Yang, 2009. ABCA1 modulates the oligomerization and Golgi exit of caveolin-1 during HDL-mediated cholesterol efflux in aortic endothelial cells. Biochem. Biophys. Res. Commun., 382: 189-195.
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  18. Ho, H.C., S.L. Hsu, C.T. Ting, C.Y. Kuo and V.C. Yang, 2009. Caffeic acid phenethyl ester inhibits arterial smooth muscle cell proliferation and migration in vitro and in vivo using a local delivery system. Cell. Mol. Biol., 55: OL1161-OL1167.
    PubMed  |  

  19. Kuo, C.Y., J.C. Wang, S.L. Hsu and G.Y. Hwang, 2008. Functional characterization of hepatitis B virus X protein based on the inhibition of tumorigenesis in nude mice injected with CCL13-HBx cells. Intervirology, 51: 253-260.
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  20. Kuo, C.Y., J.C. Wang, C.C. Wu, S.L. Hsu and G.Y. Hwang, 2008. Effects of hepatitis B virus X protein (HBx) on cell-growth inhibition in a CCL13-HBx stable cell line. Intervirology, 51: 26-32.
    CrossRef  |  Direct Link  |  

  21. Kuo, C.Y., C.C. Wu, S.L. Hsu and G.Y. Hwang, 2008. HBx inhibits the growth of CCL13-HBX-stable cells via the GSK-3β/β-catenin cascade. Intervirology, 51: 130-136.
    CrossRef  |  Direct Link  |  
Member since March, 2019