Dr. Fu Ming Tsai
Research AssociateThe Buddhist Tzuchi Medical Foundation, Taiwan
Highest Degree
Ph.D. in Medical Microbiology and Immunology from National Denfense Medical Center, Taiwan
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Area of Interest:
Selected Publications
- Wang, T.S., Y.C. Chen, F.M. Tsai, Y.Y. Chang, Y.H. Chen, C.Y. Kuo and M.L. Chen, 2020. MicroRNA expression profiles in C6 glioblastoma cell line treated with antipsychotics. Indian J. Pharm. Sci., 82: 409-419.
CrossRef | Direct Link | - Wang, C.H., L.K. Wang, C.C. Wu, M.L. Chen, C.Y. Kuo, R.Y. Shyu and F.M. Tsai, 2020. Cathepsin V mediates the tazarotene-induced gene 1-induced reduction in invasion in colorectal cancer cells. Cell Biochem. Biophys., 78: 483-494.
CrossRef | Direct Link | - Wang, C.C., L.K. Wang, M.L. Chen, C.Y. Kuo, F.M. Tsai and C.H. Wang, 2020. Triterpenes in the ethanol extract of Poria cocos induce dermal papilla cell proliferation. Int. J. Pharmacol., 16: 1-9.
CrossRef | Direct Link | - Kuo, C.Y., V. Chiu, P.C. Hsieh, C.Y. Huang and S.J. Huang, et al., 2020. Chrysophanol attenuates hepatitis B virus X protein-induced hepatic stellate cell fibrosis by regulating endoplasmic reticulum stress and ferroptosis. J. Pharmacol. Sci., 144: 172-182.
CrossRef | Direct Link | - Chen, Y.C., F.M. Tsai and M.L. Chen, 2020. Antipsychotic drugs reverse MK801-inhibited cell migration and F-actin condensation by modulating the rho signaling pathway in B35 cells. Behav. Neurol., 10.1155/2020/4163274.
CrossRef | Direct Link | - Yeh, Y.H., C.Y. Liang, M.L. Chen, F.M. Tsai and Y.Y. Lin et al., 2019. Apoptotic effects of hsianâ€tsao (Mesona procumbens Hemsley) on hepatic stellate cells mediated by reactive oxygen species and ERK, JNK and caspaseâ€3 pathways. Food Sci. Nutr., 7: 1891-1898.
CrossRef | Direct Link | - Wang, C.H., L.K. Wang, C.C. Wu, M.L. Chen, M.C. Lee, Y.Y. Lin and F.M. Tsai, 2019. The ribosomal protein RPLP0 mediates PLAAT4-induced cell cycle arrest and cell apoptosis. Cell Biochem. Biophys., 77: 253-260.
CrossRef | Direct Link | - Tsai, F.M., L.K. Wang, M.L. Chen, M.C. Lee, Y.Y. Lin and C.H. Wang, 2019. Induction of cell proliferation and cell death in human follicle dermal papilla cells by zinc chloride. Indian J. Pharm. Sci., 81: 781-785.
Direct Link | - Tsai, F.M., C.H. Li, L.K. Wang, M.L. Chen, M.C. Lee, Y.Y. Lin and C.H. Wang, 2019. Extracellular signal-regulated kinase mediates ebastine-induced human follicle dermal papilla cell proliferation. BioMed Res. Int., Vol. 2019. 10.1155/2019/6360503.
CrossRef | Direct Link | - Shyu, R.Y., C.H. Wang, C.C. Wu, L.K. Wang and M.L. Chen, et al., 2019. Tazarotene-induced gene 1 (TIG1) interacts with serine protease inhibitor kazal-type 2 (SPINK2) to inhibit cellular invasion of testicular carcinoma cells. BioMed. Res. Int., 10.1155/2019/6171065.
CrossRef | Direct Link | - Huang, K.L., H.L. Chang, F.M. Tsai, Y.H. Lee, C.H. Wang and T.J. Cheng, 2019. The effect of the inhalation of and topical exposure to zinc oxide nanoparticles on airway inflammation in mice. Toxicol. Appl. Pharmacol., 10.1016/j.taap.2019.114787.
CrossRef | Direct Link | - Wang, L.K., F.M. Tsai, M.L. Chen, S. Wu and M.C. Lee et al., 2018. Aqueous extract of Tournefortia sarmentosa stem inhibits ADP-induced platelet aggregation. Indian J. Pharm. Sci., 80: 126-134.
Direct Link | - Wang, C.H., R.Y. Shyu, C.C. Wu, M.L. Chen and M.C. Lee et al., 2018. Tazarotene-induced gene 1 interacts with DNAJC8 and regulates glycolysis in cervical cancer cells. Mol. Cells, 41: 562-574.
Direct Link | - Li, T., M. Lee, F. Tsai, Y. Chen, Y. Lin and M. Chen, 2018. Proteomic study revealed antipsychotics-induced nuclear protein regulations in B35 cells are similar to the regulations in C6 cells and rat cortex. BMC Pharmacol. Toxicol., Vol. 19. 10.1186/s40360-018-0199-0.
CrossRef | Direct Link | - Wu, C.C., F.M. Tsai, M.L. Chen, S. Wu and M.C. Lee et al., 2016. Antipsychotic drugs inhibit platelet Aggregation via P2Y1 and P2Y12 receptors. BioMed Res. Int., Vol. 2016. 10.1155/2016/2532371.
CrossRef | Direct Link | - Shyu, R.Y., C.H. Wang, C.C. Wu, M.L. Chen and M.C. Lee et al., 2016. Tazarotene-induced gene 1 enhanced cervical cell autophagy through transmembrane protein 192. Mol. Cells, 39: 877-887.
Direct Link | - Chen, M.L., F.M. Tsai, M.C. Lee and Y.Y. Lin, 2016. Antipsychotic drugs induce cell cytoskeleton reorganization in glial and neuronal cells via Rho/Cdc42 signal pathway. Progr. Neuro-Psychopharmacol. Biol. Psychiatry, 71: 14-26.
CrossRef | Direct Link | - Tsai, F.M., M.L. Chen, L.K. Wang and M.C. Lee, 2015. H-rev107 regulates cytochrome P450 reductase activity and increases lipid accumulation. PLoS ONE, Vol. 10. 10.1371/journal.pone.0138586.
CrossRef | Direct Link | - Wang, C.H., R.Y. Shyu, C.C. Wu, T.C. Tsai and L.K. Wang et al., 2014. Phospholipase A/Acyltransferase enzyme activity of H-rev107 inhibits the H-RAS signaling pathway. J. Biomed. Sci., Vol. 21. 10.1186/1423-0127-21-36.
CrossRef | Direct Link | - Chen, M.L., S. Wu, T.C. Tsai, L.K. Wang, W.M. Chou and F.M. Tsai, 2014. The caffeic acid in aqueous extract of Tournefortia sarmentosa enhances neutrophil phagocytosis of Escherichia coli. Immunopharmacol. Immunotoxicol., 36: 390-396.
CrossRef | Direct Link | - Chen, M.L., S. Wu, T.C. Tsai, L.K. Wang and F.M. Tsai, 2014. Regulation of neutrophil phagocytosis of Escherichia coli by antipsychotic drugs. Int. Immunopharmacol., 23: 550-557.
CrossRef | Direct Link | - Shyu, R.Y., C.C. Wu, C.H. Wang, T.C. Tsai and L.K. Wang et al., 2013. H-rev107 regulates prostaglandin D2 synthase-mediated suppression of cellular invasion in testicular cancer cells. J. Biomed. Sci., Vol. 20. 10.1186/1423-0127-20-30.
CrossRef | Direct Link | - Chen, M.L., S. Wu, T.C. Tsai, L.K. Wang, W.M. Chou and F.M. Tsai, 2013. Effect of aqueous extract of Tournefortia sarmentosa on the regulation of macrophage immune response. Int. Immunopharmacol., 17: 1002-1008.
CrossRef | Direct Link | - Chen, M.L., S. Wu, T.C. Tsai, L.K. Wang and F.M. Tsai, 2013. Regulation of macrophage immune responses by antipsychotic drugs. Immunopharmacol. Immunotoxicol., 35: 573-580.
CrossRef | Direct Link | - Wu, C.C., R.Y. Shyu, C.H. Wang, T.C. Tsai and L.K. Wang et al., 2012. Involvement of the prostaglandin D2 signal pathway in retinoid-inducible gene 1 (RIG1)-mediated suppression of cell invasion in testis cancer cells. Biochim. Biophys. Acta (BBA)-Mol. Cell Res., 1823: 2227-2236.
CrossRef | Direct Link | - Chen, M.L., T.C. Tsai, L.K. Wang, Y.Y. Lin, Y.M. Tsai, M.C. Lee and F.M. Tsai, 2012. Risperidone modulates the cytokine and chemokine release of dendritic cells and induces TNF-α-directed cell apoptosis in neutrophils. Int. Immunopharmacol., 12: 197-204.
CrossRef | Direct Link | - Chen, M.L., T.C. Tsai, L.K. Wang, Y.Y. Lin, Y.M. Tsai, M.C. Lee and F.M. Tsai, 2012. Clozapine inhibits Th1 cell differentiation and causes the suppression of IFN-γ production in peripheral blood mononuclear cells. Immunopharmacol. Immunotoxicol., 34: 686-694.
CrossRef | Direct Link | - Wu, C.C., F.M. Tsai, R.Y. Shyu, Y.M. Tsai, C.H. Wang and S.Y. Jiang, 2011. G protein-coupled receptor kinase 5 mediates Tazarotene-induced gene 1-induced growth suppression of human colon cancer cells. BMC Cancer, Vol. 11. 10.1186/1471-2407-11-175.
CrossRef | Direct Link | - Tsai, F.M., C.C. Wu, R.Y. Shyu, C.H. Wang and S.Y. Jiang, 2011. Tazarotene-induced gene 1 inhibits prostaglandin E2-stimulated HCT116 colon cancer cell growth. J. Biomed. Sci., Vol. 18. 10.1186/1423-0127-18-88.
CrossRef | Direct Link | - Chen, M.L., T.C. Tsai, Y.Y. Lin, Y.M. Tsai, L.K. Wang, M.C. Lee and F.M. Tsai, 2011. Antipsychotic drugs suppress the AKT/NF-kappaB pathway and regulate the differentiation of T-cell subsets. Immunol. Lett., 140: 81-91.
CrossRef | - Tsai, F.M., R.Y. Shyu, S.C. Lin, C.C. Wu and S.Y. Jiang, 2009. Induction of apoptosis by the retinoid inducible growth regulator RIG1 depends on the NC motif in HtTA cervical cancer cells. BMC Cell Biol., Vol. 10. 10.1186/1471-2121-10-15.
CrossRef | Direct Link | - Shyu, R.Y., Y.C. Hsieh, F.M. Tsai, C.C. Wu and S.Y. Jiang, 2008. Cloning and functional characterization of the HRASLS2 gene. Amino Acids, 35: 129-137.
CrossRef | Direct Link | - Tsai, F.M., R.Y. Shyu and S.Y. Jiang, 2007. RIG1 suppresses Ras activation and induces cellular apoptosis at the Golgi apparatus. Cell. Signall., 19: 989-999.
CrossRef | Direct Link | - Tsai, F.M., R.Y. Shyu and S.Y. Jiang, 2006. RIG1 inhibits the Ras/mitogen-activated protein kinase pathway by suppressing the activation of Ras. Cell. Signall., 18: 349-358.
CrossRef | Direct Link |