Dr. Yen-Hung Chow

Associate Investigator
National Defense Medical Center, Taiwan

Highest Degree
Ph.D. in Virology and Vaccinology from National Defense Medical Center, Taiwan

My URL
https://livedna.org/886.5521

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Biography

Dr. Yen-Hung Chow is currently working as Associate Investigator. He has completed his Ph.D. in Virology and Vaccinology from National Defense Medical Center, Taiwan. His main area of interest focuses on Biomedical Sciences. His area of expertise includes Virology, SCARB2, EV71, Vaccinology, JSRV, Enterovirus, Vaccine, RSV, and Transgenic. He has published 29 research articles in journals contributed as author/co-author.

Area of Interest:

Biomedical Sciences
Virology
Vaccinology
Enterovirus
Transgenic

Selected Publications

  1. Lin, Y.W., S.L. Yu, H.Y. Shao, H.Y. Lin and C.C. Liu et al., 2013. Human SCARB2 transgenic mice as an infectious animal model for enterovirus 71. PLoS One, Vol. 8., 10.1371/journal.pone.0057591.
    CrossRef  |  

  2. Lin, H.Y,.Y.T. Yang, K.N. Hsiao, S.L. Yu, C.C. Liu, C. Sia and Y.H. Chow, 2013. Caveolar endocytosis is required for human PSGL-1-mediated enterovirus 71 infection. J. Virol. .

  3. Lin, Y.W., H.Y. Lin, Y.L. Tsou, E. Chitra and K.N. Hsiao et al., 2012. Human SCARB2-mediated entry and endocytosis of EV71. PLoS One, Vol. 7., 10.1371/journal.pone.0030507.
    CrossRef  |  PubMed  |  

  4. Chou, A.H., C.C. Liu, J.Y. Chang, S.P. Lien and M.S. Guo et al., 2012. Immunological evaluation and comparison of different EV71 vaccine candidates. Clin. Develop. Immunol., Vol. 2012., 10.1155/2012/831282.
    CrossRef  |  PubMed  |  

  5. Chou, A.H., C.C. Liu, C.P. Chang, M.S. Guo and S.Y. Hsieh et al., 2012. Pilot scale production of highly efficacious and stable enterovirus 71 vaccine candidates. PLoS One, Vol. 7., 10.1371/journal.pone.0034834.
    CrossRef  |  PubMed  |  

  6. Chong, P., S.Y. Hsieh, C.C. Liu, A.H. Chou and J.Y. Chang et al., 2012. Production of EV71 vaccine candidates. Human Vaccin. Immunother., 8: 1775-1783.
    CrossRef  |  PubMed  |  Direct Link  |  

  7. Shao, H.Y., Y.W. Lin, S.L. Yu, H.Y. Lin and E. Chitra et al., 2011. Immunoprotectivity of HLA-A2 CTL peptides derived from respiratory syncytia virus fusion protein in HLA-A2 transgenic mouse. PLoS One, Vol. 6., 10.1371/ journal.pone. 0025500.
    CrossRef  |  PubMed  |  

  8. Liu, C.C., H.W. Chang, G. Yang, J.R. Chiang and Y.H. Chow et al., 2011. Development of a quantitative enzyme linked immunoosorbent assay for monitoring Enterovirus 71 vaccine manufacturing process. J. Virol. Methods, 176: 60-68.
    CrossRef  |  PubMed  |  Direct Link  |  

  9. Liu, C.C., A.H. Chou, S.P. Lien, H.Y. Lin and S.J. Liu et al., 2011. Identification and characterization of a cross-neutralization epitope of Enterovirus 71. Vaccine, 29: 4362-4372.
    CrossRef  |  PubMed  |  Direct Link  |  

  10. Chang, H.W., C.C. Liu, M.H. Lin, H.M. Ho and Y.T. Yang et al., 2011. Generation of murine monoclonal antibodies which cross-neutralize human enterovirus genogroup B isolates. J. Virol. Methods, 173: 189-195.
    CrossRef  |  PubMed  |  Direct Link  |  

  11. Chow, Y.H., H.W. Chang, R. Sia, P. Chong and C. Sia, 2011. Tonsillar CD4+FOXP3+ T regulatory cell dynamics in primary EBV infection. Immunol. Res., 50: 97-101.
    CrossRef  |  PubMed  |  Direct Link  |  

  12. Chitra, E., Y.W. Lin, F. Davamani, K.N. Hsiao and C. Sia et al., 2010. Functional interaction between Env oncogene of Jaagsiekte sheep retrovirus and tumor suppressor human Sprouty2. Retrovirology, Vol. 7., 10.1186/1742-4690-7-62 http://www.ncbi.nlm.nih.gov/pubmed/20678191.
    CrossRef  |  PubMed  |  

  13. Shao, H.Y., S.L. Yu, C. Sia, Y. Chen and E. Chitra et al., 2009. Immunogenic properties of RSV-B1 fusion (F) protein gene-encoding recombinant adenoviruses. Vaccine, 27: 5460-5471.
    CrossRef  |  PubMed  |  

  14. Chitra, E., S.L. Yu, K.N. Hsiao, H.Y. Shao and C. Sia et al., 2009. Generation and characterization of JSRV envelope transgenic mice in FVB background. Virology, 393: 120-126.
    CrossRef  |  

  15. Chang, H.W., Y.H. Chow, P. Chong and C. Sia, 2007. The cross-regulatory relationship between human dendritic and regulatory T cells and its role in type 1 diabetes mellitus. Rev. Diabet. Stud., 4: 68-76.
    CrossRef  |  PubMed  |  Direct Link  |  

  16. Varela, M., Y.H. Chow, C. Sturkie and M. Palmarini, 2006. Activation of receptor tyrosine kinase/RON in retroviral Env-mediated transformation. Virology, 350: 347-357.

  17. Zavala, G., C. Pretto, Y.H. Chow, L. Jones and A. Alberti et al., 2003. Relevance of Akt phosphorylation in cell transformation induced by Jaagsiekte sheep retrovirus. Virology, 312: 95-105.
    CrossRef  |  

  18. Xiao, X., S. Phogat, Y. Shu, A. Phogat and Y.H. Chow et al., 2003. Purified complexes of HIV-1 envelope glycoproteins with CD4 and CCR5(CXCR4): Production, characterization and immunogenicity. Vaccines, 21: 4275-4284.
    CrossRef  |  PubMed  |  

  19. Chow, Y.H.J., A. Alberti, M. Mura, C. Pretto, P. Murcia, L.M. Albritton and M. Palmarini, 2003. Transformation of rodent fibroblasts by the Jaagsiekte sheep retrovirus envelope is receptor independent and does not require the surface domain. J. Virol., 77: 6341-6350.
    CrossRef  |  Direct Link  |  

  20. Chow, Y.H., O.L. Wei, S. Phogat, I.A. Sidorov, T.R. Fouts, C.C. Broder and D.S. Dimitrov, 2002. Conserved structures exposed in HIV-1 envelope glycoproteins stabilized by flexible linkers as potent entry inhibitors and potential immunogens. Biochemistry, 41: 7176-7182.
    CrossRef  |  PubMed  |  

  21. Chow, Y.H., D. Yu, J.Y. Zhang, Y. Xie and O.L. Wei et al., 2002. Gp120-Independent infection of CD4(-) epithelial cells and CD4(+) T-cells by HIV-1. J. Acquir.Immune Defic. Syndr., 30: 1-8.
    PubMed  |  

  22. Biragyn, A., I.M. Belyakov, Y.H. Chow, D.S. Dimitrov, J.A. Berzofsky and L.W. Kwak, 2002. DNA vaccines encoding human immunodeficiency virus-1 glycoprotein 120 fusions with proinflammatory chemoattractants induce systemic and mucosal immune responses. Blood, 100: 1153-1159.
    PubMed  |  

  23. Yu, D., D. Chen, C. Chiu, B. Razmazma, Y.H. Chow and S. Pang, 2001. Prostate-specific targeting using PSA promoter-based lentiviral vectors. Cancer Gene. Ther., 8: 628-635.
    PubMed  |  

  24. Pang, S., D. Yu, D.S. An, G.C. Baldwin and Y. Xie et al., 2000. Human immunodeficiency virus env-independent infection of human CD4- cells. J. Virol., 74: 10994-11000.
    CrossRef  |  Direct Link  |  

  25. Lee, Y.L., M.H. Tao, Y.H. Chow and B.L. Chiang, 1998. Construction of vectors expressing bioactive heterodimeric and single-chain murine interleukin-12 for gene therapy. Human. Gene. Ther., 9: 457-465.
    PubMed  |  

  26. Chow, Y.H., B.L. Chiang, Y.L. Lee, W.K. Chi, W.C. Lin, Y.T. Chen and M.H. Tao, 1998. Development of Th1 and Th2 populations and the nature of immune responses to hepatitis B virus DNA vaccines can be modulated by codelivery of various cytokine genes. J. Immunol., 160: 1320-1329.
    PubMed  |  Direct Link  |  

  27. Chow, Y.H., W.L. Huang, W.K. Chi, Y. Chu and M.H. Tao, 1997. Improvement of hepatitis B virus DNA vaccines by plasmids coexpressing hepatitis B surface antigen and interleukin-2. J. Virol., 71: 169-178.
    Direct Link  |  

  28. Chang, W.C., G.Y. Shi, Y.H. Chow, L.C. Chang and J.S. Hau et al., 1993. Human plasmin induces a receptor-mediated arachidonate release coupled with g proteins in endothelial cells. Am. J. Physiol., 264: C271-C281.
    PubMed  |  Direct Link  |  

  29. Shi, G.Y., J.S. Hau, S.J. Wang, I.S. Wu and B.I. Chang et al., 1992. Plasmin and the regulation of tissue-type plasminogen activator biosynthesis in human endothelial cells. J. Biolo. Chem., 267: 19363-19368.
    PubMed  |  Direct Link  |  
Member since December, 2015