Dr. Ho Lin

Professor
National Chung Hsing University, Taiwan

Highest Degree
Ph.D. in Physiology from National Yang-Ming University, Taipei, Taiwan

My URL
https://livedna.org/886.6476

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Area of Interest:

Molecular Sciences
Cell Biology
Neurobiology
Pharmacology
Reproduction

Selected Publications

  1. Wang, H.Y., W.Y. Lin, M.C. Chen, T. Lin and C.H. Chao et al., 2013. Inhibitory effects of Rhenium-188-labeled Herceptin on prostate cancer cell growth: A possible radioimmunotherapy to prostate carcinoma. Int. J. Radiat. Biol., 89: 346-355.
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  2. Lin, E., H. Lin, G.U. Hung, J.C.H. Wu and H.L. Hsieh et al., 2013. Spontaneous rupture of the bladder after a seizure: A pitfall of diagnosis. Surg. Sci., 4: 128-130.

  3. Huang, P.H., C.Y. Huang, M.C. Chen, Y.T. Lee, C.H. Yue, H.Y. Wang and H. Lin, 2013. Emodin and aloe-emodin suppress breast cancer cell proliferation through ERα inhibition. Evidence Based Complement. Altern. Med., 10.1155/2013/376123.
    CrossRef  |  Direct Link  |  

  4. Hsu, F.N., M.C. Chen, K.C. Lin, Y.T. Peng and P.C. Li et al., 2013. Cyclin-dependent kinase 5 modulates STAT3 and androgen receptor activation through phosphorylation of Ser727 on STAT3 in prostate cancer cells. Am. J. Physiol. Endocrinol. Metab., 305: E975-E986.
    CrossRef  |  Direct Link  |  

  5. Hsiao, H.B., H. Lin, J.B. Wu and W.C. Lin, 2013. Kinsenoside prevents ovariectomy-induced bone loss and suppresses osteoclastogenesis by regulating classical NF-κB pathways. Osteoporosis Int., 24: 1663-1676.
    CrossRef  |  Direct Link  |  

  6. Lin, H.Y., W.L. Yeh, B.R. Huang, C. Lin, C.H. Lai, H. Lin and D.Y. Lu, 2012. Desipramine protects neuronal cell death and induces heme oxygenase-1 expression in Mes23.5 dopaminergic neurons. PloS One, Vol. 7. 10.1371/journal.pone.0050138.
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  7. Lin, H. and P.S. Wang, 2012. Inhibitory effects of digoxin on testosterone production in rat Leydig cells. Adapt. Med., 4: 165-173.
    CrossRef  |  Direct Link  |  

  8. Lee, Y.T., H. Lin, J.C. Guo, S.L. Yan and H.J. Hou et al., 2012. Laparoscopy-assisted billroth I gastrectomy for ectopic pancreas in the prepyloric region. Case Rep. Gastroenterol., 6: 712-719.
    CrossRef  |  

  9. Chen, M.C., C.Y. Huang, S.L. Hsu, E. Lin, C.T. Ku, H. Lin and C.M. Chen, 2012. Retinoic acid induces apoptosis of prostate cancer DU145 cells through Cdk5 overactivation. Evidence Based Complement. Altern. Med., 10.1155/2012/580736.
    CrossRef  |  Direct Link  |  

  10. Chang, C.T., T.Y. Ho, H. Lin, J.A. Liang and H.C. Huang et al., 2012. 5-Fluorouracil induced intestinal mucositis via nuclear factor-κB activation by transcriptomic analysis and in vivo bioluminescence imaging. PLoS One, Vol. 7. 10.1371/journal.pone.0031808.
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  11. Lien, H.M., P.T. Kuo, C.L. Huang, J.Y. Kao and H. Lin et al., 2011. Study of the anti-proliferative activity of 5-substituted 4, 7-dimethoxy-1, 3-benzodioxole derivatives of SY-1 from Antrodia camphorate on human COLO 205 colon cancer cells. Evidence-Based Complem. Altern. Med., Vol. 2011 10.1093/ecam/nep230.
    CrossRef  |  

  12. Hsu, F.N., M.S. Yang, E. Lin, C.F. Tseng and H. Lin, 2011. The significance of Her2 on androgen receptor protein stability in the transition of androgen requirement in prostate cancer cells. Am. J. Physiol. Endocrinol. Metab., 300: E902-E908.
    CrossRef  |  Direct Link  |  

  13. Hsu, F.N., M.C. Chen, M.C. Chiang, E. Lin and Y.T. Lee et al., 2011. Regulation of androgen receptor and prostate cancer growth by cyclin-dependent kinase 5. J. Biol. Chem., 286: 33141-33149.
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  14. Hsiao, H.B., J.B. Wu, H. Lin and W.C. Lin, 2011. Kinsenoside isolated from Anoectochilus formosanus suppresses LPS-stimulated inflammatory reactions in macrophages and endotoxin shock in mice. Shock, 35: 184-190.
    CrossRef  |  Direct Link  |  

  15. Chang, C.T., H. Lin, T.Y. Ho, C.C. Li and H.Y. Lo et al., 2011. Comprehensive assessment of host responses to ionizing radiation by nuclear factor-κB bioluminescence imaging-guided transcriptomic analysis. PloS One, Vol. 6 10.1371/journal.pone.0023682.g002.
    CrossRef  |  

  16. Lee, Y.T., H. Lin, K.Y. Chen, H.S. Wu, M.H. Hwang and S.L. Yan, 2010. Life-threatening hemobilia caused by hepatic pseudoaneurysm after T-tube choledochostomy: Report of a case. BMC Gastroenterol., Vol. 10 10.1186/1471-230X-10-81.
    CrossRef  |  

  17. Chen, M.C., H. Lin, F.N. Hsu, P.H. Huang, G.S. Lee and P.S. Wang, 2010. Involvement of cAMP in nerve growth factor-triggered p35/Cdk5 activation and differentiation in PC12 cells. Am. J. Physiol. Cell Physiol., 299: C516-C527.
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  18. Chen, C.H., H. Lin, S.M. Chuang, S.Y. Lin and J.J. Chen, 2010. Acidic stress facilitates tyrosine phosphorylation of HLJ1 to associate with actin cytoskeleton in lung cancer cells. Exp. Cell Res., 316: 2910-2921.
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  19. Lin, H., M.C. Chen and C.T. Ku, 2009. Cyclin-dependent kinase 5 regulates steroidogenic acute regulatory protein and androgen production in mouse Leydig cells. Endocrinology, 150: 396-403.
    CrossRef  |  PubMed  |  Direct Link  |  

  20. Lin, H., 2009. The versatile roles of cyclin-dependent kinase 5 in human diseases. Adapt Med., 1: 22-25.
    Direct Link  |  

  21. Lee, W.J., C.S. Wu, H. Lin, I.T. Lee and C.M. Wu et al., 2009. Visfatin-induced expression of inflammatory mediators in human endothelial cells through the NF-κB pathway. Int. J. Obesity, 33: 465-472.
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  22. Kuo, H.S., F.N. Hsu, M.C. Chiang, S.C. You, M.C. Chen, M.J. Lo and H. Lin, 2009. The role of Cdk5 in retinoic acid-induced apoptosis of cervical cancer cell line. Chinese J. Physiol., 52: 23-30.
    PubMed  |  Direct Link  |  

  23. Yan, S.L., H. Lin, C.L. Kuo, H.S. Wu, M.H. Huang and Y.T. Lee, 2008. Primary retroperitoneal mucinous cystadenoma: Report of a case and review of the literature. World J. Gastroenterol., 14: 5769-5772.
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  24. Lin, E., H. Lin, M.S. Lin, J.C.H. Wu, W.C. Chen and A.W. Chiu, 2008. Laparoscopic excision of a paraganglioma located in the renal arteriovenous windows- a reasonable approach. Open Urol. Nephrol. J., 1: 40-43.
    CrossRef  |  

  25. Lee, Y.T., H. Lin, Y.T. Tseng, M.A. Hwang, C.L. Kuo, H.S. Wu and M.H. Hwang, 2008. Large epidermoid cyst of the breast: Report of a case. Formosan J. Surg., 41: 221-225.
    Direct Link  |  

  26. Lin, H., T.Y. Lin and J.L. Juang, 2007. Abl deregulates Cdk5 kinase activity and subcellular localization in Drosophila neurodegeneration. Cell Death Differentiation, 14: 607-615.
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  27. Lin, H., M.C. Chen, C.Y. Chiu, Y.M. Song and S.Y. Lin, 2007. Cdk5 regulates STAT3 activation and cell proliferation in medullary thyroid carcinoma cells. J. Biol. Chem., 282: 2776-2784.
    CrossRef  |  Direct Link  |  

  28. Lin, H., J.L. Juang and P.S. Wang, 2004. Involvement of Cdk5/p25 in digoxin-triggered prostate cancer cell apoptosis. J. Biol. Chem., 279: 29302-29307.
    Direct Link  |  

  29. Lin, H., S.W. Wang, R.Y. Wang and P.S. Wang, 2001. Stimulatory effect of lactate on testosterone production by rat Leydig cells. J. Cell. Biochem., 83: 147-154.
    CrossRef  |  

  30. Lin, H., C.H. Chien, Y.L. Lin, C.F. Chen and P.S. Wang, 2000. Inhibition of testosterone secretion by S-petasin in rat testicular interstitial cells. Chin. J. Physiol., 43: 99-103.
    Direct Link  |  

  31. Chiao, Y.C., H. Lin, S.W. Wang and P.S. Wang, 2000. Direct effects of propylthiouracil on testosterone secretion in rat testicular interstitial cells. Br. J. Pharmacol., 130: 1477-1482.
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  32. Wang, S.W., H. Lin, J.J. Hwang and P.S. Wang, 1999. Inhibition of testosterone secretion by digitoxin in rat testicular interstitial cells. J. Cell. Biochem., 74: 74-80.
    CrossRef  |  Direct Link  |  

  33. Lo, M.J., M.M. Kau, J.J. Chen, J.Y. Yeh, H. Lin, S.W. Wang and P.S. Wang, 1999. Age-related differences in corticosterone secretion in female rats. Metabolism, 48: 535-541.
    CrossRef  |  PubMed  |  Direct Link  |  

  34. Lin, H., S.C. Tsai, J.J. Chen, Y.C. Chiao and S.W. Wang et al., 1999. Effects of evodiamine on the secretion of testosterone in rat testicular interstitial cells. Metabolism, 48: 1532-1535.
    CrossRef  |  Direct Link  |  

  35. Kau, M.M., M.J. Lo, S.W. Wang, S.C. Tsai and J.J. Chen et al., 1999. Inhibition of aldosterone production by testosterone in male rats. Metabolism, 48: 1108-1114.
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  36. Kau, M.M., M.J. Lo, S.C. Tsai, J.J. Chen and C.C. Lu et al., 1999. Effects of estradiol on aldosterone secretion in ovariectomized rats. J. Cell. Biochem., 73: 137-144.
    CrossRef  |  Direct Link  |  

  37. Huang, W.J., J.Y. Yeh, S.C. Tsai, H. Lin and Y.C. Chiao et al., 1999. Regulation of testosterone secretion by prolactin in male rats. J. Cell. Biochem., 74: 111-118.
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  38. Chang, L.L., M.J. Lo, S.F. Kan, W.J.S. Huang and J.J. Chen et al., 1999. Direct effects of prolactin on corticosterone release by zona fasciculata‐reticularis cells from male rats. J. Cell. Biochem., 73: 563-572.
    CrossRef  |  Direct Link  |  

  39. Lin, H., S.W. Wang, S.C. Tsai, J.J. Chen and Y.C. Chiao et al., 1998. Inhibitory effect of digoxin on testosterone secretion through mechanisms involving decreases of cyclic AMP production and cytochrome P450scc activity in rat testicular interstitial cells. Br. J. Pharmacol., 125: 1635-1640.
    CrossRef  |  Direct Link  |  

  40. Doong, M.L., C.C. Lu, M.M. Kau, S.C. Tsai and Y.C. Chiao et al., 1998. Inhibition of gastric emptying and intestinal transit by amphetamine through a mechanism involving an increased secretion of CCK in male rats. Br. J. Pharmacol., 124: 1123-1130.
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  41. Wang, S.W., Y.C. Chiao, S.C. Tsai, C.C. Lu and J.J. Chen et al., 1997. Inhibition of bufalin on pituitary and testicular function in rats. J. Pharmacol. Exp. Ther., 283: 528-532.
    Direct Link  |  

  42. Tsai, S.C., J.J. Chen, Y.C. Chiao, C.C. Lu and H. Lin et al., 1997. The role of cyclic AMP production, calcium channel activation and enzyme activities in the inhibition of testosterone secretion by amphetamine. Br. J. Pharmacol., 122: 949-955.
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Member since February, 2014