Dr. Ahmet Gokhan Akkan
Head of DepartmentIstanbul University, Turkiye
Highest Degree
Ph.D. in Pharmacology from Istanbul University, Istanbul, Turkiye
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Area of Interest:
Selected Publications
- Shahzadi, A., T. Uskur, A.G. Akkan, B. Cevreli and T. Uzbay, 2017. Effects of propofol on conditioned place preference in male rats: Involvement of nitrergic system. Am. J. Drug Alcohol Abuse, (In Press). 10.1080/00952990.2017.1344681.
CrossRef | Direct Link | - Ozyazgan, S., B. Onal, E.M. Kurtulus, H. Uzun, G. Akkan and D. Konukoglu, 2017. Plasma betatrophin levels of subjects classified with normal, impaired and diabetic glucose tolerance and subjects with impaired fasting glucose. Hormone Metab. Res., 49: 434-439.
CrossRef | Direct Link | - Uskur, T., M.A. Barlas, A.G. Akkan, A. Shahzadi and T. Uzbay, 2016. Dexmedetomidine induces conditioned place preference in rats: Involvement of opioid receptors. Behav. Brain Res., 296: 163-168.
CrossRef | Direct Link | - Demir, B., B. Onal, S. Ozyazgan, C. Kandaz and H. Uzun et al., 2016. Does inflammation have a role in the pathogenesis of cardiac syndrome X? A genetic-based clinical study with assessment of multiple cytokine levels. Angiology, 67: 355-363.
CrossRef | Direct Link | - Afsar, S., D. Hemsinli, S. Ozyazgan, A.G. Akkan and C. Arslan, 2016. The effects of potassium channels in human internal mammary artery. Pharmacology, 97: 72-77.
CrossRef | Direct Link | - Altınok, A., Z.M. Coskun, K. Karaoglu, S. Bolkent, A.G. Akkan and S. Ozyazgan, 2015. Δ9-tetrahydrocannabinol treatment improved endothelium-dependent relaxation on streptozotocin/nicotinamide-induced diabetic rat aorta. Acta Physiol. Hung., 102: 51-59.
CrossRef | Direct Link | - Shahzadi, A., I. Sonmez, O. Allahverdiyev, B. Onal and C. Kandaz et al., 2014. Cardiac troponin-I (cTnI) a biomarker of cardiac injuries induced by doxorubicin alone and in combination with ciprofloxacin, following acute and chronic dose protocol in sprague dawley rats. Int. J. Pharmacol., 10: 258-266.
CrossRef | Direct Link | - Ozturk, M., S. Bolkent, F. Kaya-Dagistanli, M. Tuncdemir, S. Yilmazer and A.G. Akkan, 2006. The effects of 5-aminoimidazole-4-carboxamide riboside on the pancreas in neonatal streptozotocin-diabetic rats. Acta Diabetol., 43: 61-65.
CrossRef | Direct Link | - Ozyazgan, S., N. Kutluata, S. Afsar, S.B. Ozdas and A.G. Akkan, 2005. Effect of glucagon-like peptide-1(7-36) and exendin-4 on the vascular reactivity in streptozotocin/nicotinamide-induced diabetic rats. Pharmacology, 74: 119-126.
CrossRef | Direct Link | - Akici, A., S. Kalaca, M.Z. Goren, A.G. Akkan and A. Karaalp et al., 2004. Comparison of rational pharmacotherapy decision-making competence of general practitioners with intern doctors. Eur. J. Clin. Pharmacol., 60: 75-82.
CrossRef | Direct Link | - Unluer, E.E., A. Denizbasi, S. Ozyazgan and A.G. Akkan, 2003. Role of bombesin and cholecystokinin receptors in gastric injury induced by hemorrhagic shock in the rat. Pharmacology, 68: 74-80.
CrossRef | Direct Link | - Ozyazgan, S., B. Bicakci, A. Ozaydin, A. Denizbasi, E.E. Unluer and A.G. Akkan, 2003. The effect of agmatine on the vascular reactivity in streptozotocin-diabetic rats. Pharmacol. Res., 48: 133-138.
CrossRef | Direct Link | - Senses, V., S. Ozyazgan, Ε. Ince, Μ. Tuncdemir and F. Kaya et al., 2001. Effect of 5-aminoimidazole-4-carboxamide riboside (Aica-R) on isolated thoracic aorta responses in streptozotocin diabetic rats. J. Basic Clin. Physiol. Pharmacol., 12: 227-248.
CrossRef | Direct Link | - Ozyazgan, S., V. Senses, T. Utkan, G. Ulak, N. Gacar, Z. Ozuner and A.G. Akkan, 1998. The effect of isradipine on maximal electroshock seizures in mice. Gen. Pharmacol.: Vasc. Syst., 31: 133-135.
CrossRef | Direct Link | - Ozyazgan, S., V. Senses, E. Ince, G. Sultuybek, T. Utkan and A.G. Akkan, 1998. The effect of Succinic Acid Monomethyl ester (SAM) on the responses of isolated thoracic aorta in streptozotocin-diabetic rats. Pharmacol. Res., 38: 73-79.
CrossRef | Direct Link | - Akkan, A.G., I. Mutlu, S. Ozyazgan, A. Gok and U. Yigit et al., 1997. Penetration of topically applied ciprofloxacin, norfloxacin and ofloxacin into the aqueous humor of the uninflamed human eye. J. Chemother., 9: 257-262.
CrossRef | Direct Link | - Akkan, A.G., I. Mutlu, S. Ozyazgan, A. Gok and U. Yigit et al., 1997. Comparative tear concentrations of topically applied ciprofloxacin, ofloxacin and norfloxacin in human eyes. Int. J. Clin. Pharmacol. Therapeut., 35: 214-217.
PubMed | Direct Link | - Sener, A., A.G. Akkan and W.J. Malaisse, 1995. Standardized procedure for the assay and identification of hypoglycemic sulfonylureas in human plasma. Acta Diabetol., 32: 64-68.
CrossRef | Direct Link | - Yillar, D.O., A.G. Akkan, A. Akcasu and Z. Ozuner, 1991. The influence of choline ascorbate on the blood levels of ascorbic acid in humans. Int. J. Clin. Pharmacol. Ther. Toxicol., 29: 228-230.
PubMed | Direct Link | - Leclercq-Meyer, V., A.G. Akkan, J. Marchand and W.J. Malaisse, 1991. Effects of glimepiride and glibenclamide on insulin and glucagon secretion by the perfused rat pancreas. Biochem. Pharmacol., 42: 1634-1637.
CrossRef | Direct Link | - Akkan, A.G., D.O. Yillar, E. Eskazan, A. Akcasu and Z. Ozuner, 1989. The effect of propranolol on maximal electroshock seizures in mice. Int. J. Clin. Pharmacol. Ther. Toxicol., 27: 255-257.
PubMed | Direct Link | - Akkan, A.G., A. Akcasu and D.O. Yillar, 1988. The effect of naloxone on the blood level of morphine and histamine in morphine perfused dogs. Int. J. Clin. Pharmacol. Ther. Toxicol., 26: 594-596.
PubMed | Direct Link | - Akcasu, A., A.G. Akkan, D.O. Yillar and I.A. Aksoy, 1988. The effect of naloxone on the blood levels of morphine and histamine in morphine dependent dogs. Int. J. Clin. Pharmacol. Ther. Toxicol., 26: 317-319.
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