Dr. Sedat Altug

Medical Professional/Doctor
Gazi University, Turkiye

Highest Degree
Ph.D. in Basic and Clinical Pharmacology from Gazi University, Ankara, Turkiye

My URL
https://livedna.org/90.5511

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Biography

Dr. Sedat Altug is currently working as Senior Medical Advisor Oncology. He has completed his Ph.D. in Basic and Clinical Pharmacology from Gazi University, Ankara, Turkey. His main area of interest focuses on Pharmacology and Toxicology. His area of expertise includes Nitric Oxide, Peroxynitrite, Free Redicals, lschemia, Reperfusion, Clinical Oncology, Basic Oncology, Lung Cancer, Drug Development, Clinical Research, and Ethics. He has published 17 research articles in journals and 4 abstracts contributed as author/co-author.

Area of Interest:

Pharmacology and Toxicology
Nitric Oxide
Peroxynitrite
Free Redicals
Pharmacy

Selected Publications

  1. Yang, J.C.H., J.H. Kang, T. Mok, M.J. Ahn and V. Srimuninnimit et al., 2014. First-line pemetrexed plus cisplatin followed by gefitinib maintenance therapy versus gefitinib monotherapy in East Asian patients with locally advanced or metastatic non-squamous non-small cell lung cancer: A randomised, phase 3 trial. Eur. J. Cancer, 50: 2219-2230.
    CrossRef  |  Direct Link  |  

  2. Lee, D.H., J.S. Lee, S.W. Kim, J.R. Pereira and B. Han et al., 2013. A randomized phase 2 study of erlotinib plus pemetrexed vs erlotinib or pemetrexed alone as second-line treatment for never-smoker patients with non squamous advanced non-small cell lung cancer (NSCLC). Eur. J. Cancer, 49: 3111-3121.

  3. Li, C.T., M. Marek, S.Z. Guclu, Y. Kim and M. Meshref et al., 2011. Smoking and Prognostic Factors in an Observational Setting in Patients with Advanced Non-Small Cell Lung Carcinoma. J. Cancer, 2: 52-61.
    CrossRef  |  Direct Link  |  

  4. Chu, D.T., S.W. Kim, H.K. Hsu, G. Cok and J. Roubec et al., 2009. Patient Attitudes towards Chemotherapy and Survival: A Prospective Observational Study in Advanced Non-Small Cell Lung Cancer. Lung Cancer, 66: 250-256.
    CrossRef  |  Direct Link  |  

  5. Uludag, O., B. Tunctan, O. Uludag, B. Tunctan and S. Altug et al., 2007. Twenty‐Four‐Hour Variation of L-Arginine/Nitric Oxide/Cyclic Guanosine Monophosphate Pathway Demonstrated by the Mouse Visceral Pain Model. Chronobiol. Int., 24: 413-424.
    CrossRef  |  Direct Link  |  

  6. Chu, D.T., S.W, Kim, H.P. Kuo, R. Ozacar and F. Salajka et al., 2007. Patient Attitudes Towards Chemotherapy as Assessed by Patient Versus Physician: A Prospective Observational Study in Advanced Non-Small Cell Lung Cancer. Lung Cancer, 56: 433-443.
    CrossRef  |  Direct Link  |  

  7. Altug, S., O. Uludag, B. Tunctan, I. Cakici and H. Zengil et al., 2006. Biological Time-Dependent Difference in Effect of Peroxynitrite Demonstrated by the Mouse Hot Plate Pain Model. Chronobiol. Int., 23: 583-591.
    CrossRef  |  Direct Link  |  

  8. Tunctan, B., S. Altug, O. Uludag and N. Abacioglu, 2005. Contribution of Nitric Oxide and Tumor Necrosis Factor-α to the Effect of Indomethacin on Endotoxin-Induced Mortality. FABAD J. Pharm. Sci., 30: 1-6.
    Direct Link  |  

  9. Tunctan, B. and S. Altug, 2004. The Use of Nitric Oxide Synthase Inhibitors in Inflammatory Diseases: A Novel Class of Anti-Inflammatory Agents. Curr. Med. Chem. Anti-Inflammatory Anti-Allergy Agents, 3: 271-301.
    CrossRef  |  

  10. Tunctan, B., S. Altug, O. Uludag, B. Demirkay and N. Abacioglu, 2003. Effects of Cyclooxygenase Inhibitors on Nitric Oxide Production and Survival in a Mice Model of Sepsis. Pharmacol. Res., 48: 37-48.
    PubMed  |  Direct Link  |  

  11. Altug, S., A.T. Demiryurek, D. Ak, M. Tungel and I. Kanzik, 2001. Contribution of Peroxynitrite to the Beneficial Effects of Preconditioning on Ischaemia-Induced Arrhythmias in Rat Isolated Hearts. Eur. J. Pharmacol., 415: 239-246.
    PubMed  |  Direct Link  |  

  12. Tuntan, B., S. Altug, O. Uluda and N. Abaciolu, 2000. Time-Dependent Variations in Serum Nitrite, 6-Keto-Prostaglandin F1 and Thromboxane B2 Levels Induced by Lipopolysaccharide in Mice. Biol. Rhythm Res., 31: 499-513.

  13. Tunctan, B., S. Altug , O. Uludag and N. Abacioglu, 2000. Effects of Econazole on Receptor-Operated and Depolarization-Induced Contractions in Rat Isolated Aorta. Life Sci., 67: 2393-2401.
    PubMed  |  Direct Link  |  

  14. Altug, S., A.T. Demiryurek, K.A. Kane and I. Kanzik, 2000. Evidence for the Involvement of Peroxynitrite in ischaemic Preconditioning in Rat Isolated Hearts. Br. J. Pharmacol., 130: 125-131.
    CrossRef  |  Direct Link  |  

  15. Uludag, O., B. Tunctan, H.Z. Guney, C. Uluoglu, S. Altug, H. Zengil and N. Abacioglu, 1999. Temporal variation in serum nitrite levels in rats and mice. Chronobiol. Int., 16: 527-532.
    CrossRef  |  Direct Link  |  

  16. Altug, S., O. Uzun, A.T. Demiryurek, I. Cakici and N. Abacioglu et al., 1999. The Role of Nitric Oxide in Digoxin-Induced Arrhythmias in Guinea-Pigs. Pharmacol. Toxicol., 84: 3-8.
    Direct Link  |  

  17. Altug, S., A.T. Demiryurek, I. Cakici and I. Kanzik, 1999. The Beneficial Effects of Peroxynitrite on Ischaemia-Reperfusion Arrhythmias in Rat Isolated Hearts. Eur. J. Pharmacol., 384: 157-162.
    PubMed  |  Direct Link  |  

  18. Tunctan, B., O. Uludag , S. Altug and N. Abacioglu, 1998. Effects of Nitric Oxide Synthase Inhibition in Lipopolysaccharide-Induced Sepsis in Mice. Pharmacol. Res., 38: 405-411.
    PubMed  |  Direct Link  |  
Member since December, 2015