Dr. Mohammad Sohail

Research Scientist
Vinoba Bhave University, India


Highest Degree
Ph.D. in Public Health from National Institute Of Malaria, India

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Biography

Dr. Mohammad Sohail is presently working as Young Scientist at University Department of Zoology, Vinoba Bhave University, Hazaribag. He has received his Ph.D. in Public Health from National Institute of Malaria, India. Previously he was appointed as Post Doctoral Scientist at School of Medicine, New York University, Post Doctoral Fellow at University of California-Riverside, and Senior Research Fellow at NIMR in collaboration with Indian Council of Medical Research (ICMR), and Junior Research Fellow at Shriram Institute for Industrial Research New-Delhi, India. Dr. Sohail received honors includes Young Scientist award by International Society for Ecological Communications in an International Conference, Young International Scientists award by Chinese Academy of Sciences to work in Institute of Microbiology, Beijing, China, Young Scientist Award by Department of Science & Technology, Govt. of India, and received Award from International Society for Infectious Diseases. He has completed 2 funded research projects and currently working on 4 research projects as principal investigator and co-investigator. He is member of professional societies such as International Society for Interferon and Cytokine Research, Society for Free Radical Biology & Medicine, Clinical Immunology Society (CIS), International Cytokine Society, and International Association for DNA Vaccine. He has published 2 books, 16 research articles in journals, 9 research papers in international journals, contributed as author/co-author. He also attended number of conferences, seminars, and workshops and performed many presentations. His area of research interest focuses on Identification and Molecular characterization of Vaccine Candidate Antigens like CSP, MSP-1 and II, MSP-3 Alpha, AMA-1 etc. in P.vivax and P.falciparum Isolates, Identification and Molecular characterization of Immunomodulatory Genes like TNF and Inflammatory Interleukins in P.vivax isolates, Molecular characterization of Drug Resistance Gene like Pv-mdr-1, Pv and Pf -dhps and Pv and Pf-dhfr etc. form different locations of India in Clinical Malaria and so on.

Area of Interest:

Biomedical Sciences
Molecular Charatecrization
Vaccine
Signaling Pathways
Identification

Selected Publications

  1. Chen, G., X. Wang, M.S. Severo, O.S. Sakhon and M. Sohail et al., 2014. The tick salivary protein sialostatin L2 inhibits caspase-1-mediated inflammation during Anaplasma phagocytophilum infection. Infect. Immun., 82: 2553-2564.
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  2. Abhishek, K., M. Sohail, A. Zaidi, S. Anwar and V.P. Royet al., 2014. Genetic mutation at 567c/g of bone morphogenetic protein-6 reveals no significant involvement of pathological progression in sickle-cell disease with orthopedic complications but strongly associated with increased ldh and uric acid level in indian patients from chhattisgarh and jharkhand state. Am. J. Biochem. Biotechnol., 10: 125-136.
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  3. Hussain, M.M., M. Sohail, K. Abhishek and M. Raziuddin, 2013. Investigation on plasmodium falciparum and plasmodium vivax infection influencing host haematological factors in tribal dominant and malaria endemic population of Jharkhand. Saudi J. Biol. Sci., 20: 195-203.
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  4. Chen, G., M.S. Severo, M. Sohail, O.S. Sakhon, S.K. Wikel, M. Kotsyfakis and J.H. Pedra, 2012. Ixodes scapularis saliva mitigates inflammatory cytokine secretion during Anaplasma phagocytophilum stimulation of immune cells. Parasites Vectors, Vol. 5. 10.1186/1756-3305-5-229.
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  5. Hussain, M.M., M. Sohail, R. Kumar, O.H. Branch, T. Adak and M. Raziuddin, 2011. Genetic diversity in merozoite surface protein-1 and 2 among Plasmodium falciparum in malarious districts of tribal dominant state Jharkhand of India. Ann Trop Med Parasitol., 105: 579-592.
    PubMed  |  Direct Link  |  

  6. Sohail, M., R. Kumar, A. Kaul, E. Arif, S. Kumar and T. Adak, 2010. Polymorphism in glutathione S-transferase P1 is associated with susceptibility to Plasmodium vivax malaria compared to P. falciparum and upregulates the GST level during malarial infection. Free Radic. Biol. Med., 49: 1746-1754.
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  7. Singh, O.P., N. Nanda, V. Dev, P. Bali and M. Sohail et al., 2010. Molecular evidence of misidentification of Anopheles minimus as Anopheles fluviatilis in Assam (India). Acta Tropica, 113: 241-244.
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  8. Abhishek, K., R. Kumar, E. Arif, P.K. Patra, S.B. Choudhary and M. Sohail, 2010. Induced expression of bone morphogenetic protein-6 and smads signaling in human monocytes derived dendritic cells during sickle-cell pathology with orthopedic complications. Biochem. Biophys. Res. Commun., 396: 950-955.
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  9. Abhishek, K., M. Sohail, R. Kumar, P.K. Patra and S.B. Choudhary, 2010. Mutation -567 G/C in bone morphogenetic protein 4 do not increase the risk in sickle-cell disease with orthopedic complications but strongly associated with increased LDH and uric acid level in Indian patients from Chhattisgarh and Jharkhand State. Columban J. Life Sci., 11: 41-50.

  10. Sohail, M., A. Kaul, B. Prerna, M. Raziuddin and M.P. Singh et al., 2008. Alleles -308A and -1031C in the TNF-α gene promoter do not increase the risk but associated with circulating levels of TNF-α and clinical features of vivax malaria in indian patients. Mol. Immunol., 45: 1682-1692.

  11. Sohail, M., A. Kaul, M. Raziuddin and T. Adak, 2007. Decreased glutathione-S-transferase activity: Diagnostic and protective role in vivax malaria. Clin. Biochem., 40: 377-382.
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  12. Zafar, R., S. Ahmad and M. Sohail, 2001. Techniques and application of hairy root culture for production of secondary plant metabolites. J. Sci. Pharm., 2: 26-32.