Mr. Amit Kumar Srivastava

Research Scholar
Indian Institute of Technology Roorkee, India


Highest Degree
Ph.D. Student in Biotechnology from Indian Institute of Technology Roorkee, India

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Biography

Amit Kumar Srivastava earned his Bachelor’s in Pharmacy (2010) from Bharat Institute of Technology, Meerut, India and Master’s in Pharmacology (2013) from Truba Institute of Pharmacy, Bhopal, India. His master’s work was focused on developing the animal model and novel treatment therapies for psoriasis. He worked as a Junior Research Fellow at Department of Pharmacology, CSIR-Indian Institute of Integrative Medicine, Jammu, India, where he worked on studying the malaria epidemiology in tribal population of India and developing vaccine delivery platforms for the treatment of malaria. Currently, he is a PhD Research Scholar at the Department of Biotechnology, Indian Institute of Technology Roorkee, Roorkee, India. His research interest focuses on the development of novel strategies for the diagnosis, treatment and prevention of infectious and autoimmune diseases. He has expertise in conducting in-vivo studies of the drug molecules in the early preclinical development phase. He has authored 40 scientific publications in peer-reviewed scientific journals and also serving as a peer reviewer in 25 scientific journals of repute. He is a member of many learned societies including American Chemical Society, The Biotech Research Society, India and The Indian Science Congress Association, India.

Area of Interest:

Pharmacology and Toxicology
Drug Delivery
Autoimmune Disease
Nanomedicine
Nanobiotechnology

Selected Publications

  1. Yadav T.C., V. Agarwal, A.K. Srivastava, N. Raghuwanshi, P. Varadwaj, R. Prasad and V. Pruthi, 2019. Insight into structure-function relationships of β-lactamase and blips interface plasticity using protein-protein interactions. Current Pharmaceutical Design 25: 3378-3389.
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  2. Raghuwanshi N., T.C. Yadav, A.K. Srivastava, U. Raj, P. Varadwaj and V. Pruthi, 2019. Structure-based drug designing and identification of woodfordia fruticosa inhibitors targeted against heat shock protein (hsp70-1) as suppressor for imiquimod-induced psoriasis like skin inflammation in mice model. Materials Science and Engineering: C 95: 57-71.
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  3. Yadav T.C., A.K. Srivastava, A. Dey, N. Kumar, N. Raghuwanshi and V. Pruthi, 2018. Application of computational techniques to unravel structure-function relationship and their role in therapeutic development. Current Topics in Medicinal Chemistry 18: 1769-1791.
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  4. Pruthi V. and A.K. Srivastava, 2018. Editorial: recent therapeutic advancements using bioinformatics and chemoinformatics approaches. Current Topics in Medicinal Chemistry 18: 1717-1718.
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  5. Panwar R., N. Raghuwanshi, A.K. Srivastava, A.K. Sharma and V. Pruthi, 2018. In-vivo sustained release of nanoencapsulated ferulic acid and its impact in induced diabetes. Materials Science and Engineering: C 92: 381-392.
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  6. Vashisth, P., N. Raghuwanshi, A.K. Srivastava, H. Singh, H. Nagar and V. Pruthi, 2017. Ofloxacin loaded gellan/PVA nanofibers-synthesis, characterization and evaluation of their gastroretentive/mucoadhesive drug delivery potential. Mater. Sci. Eng.: C, 71: 611-619.
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  7. Shukla, G., A.K. Srivastava, P. Khare, R. Patidar and R. Saxena, 2017. Therapeutic potential, challenges and future perspective of cancer stem cells in translational oncology: A critical review. Curr. Stem Cell Res. Ther., 12: 207-224.
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  8. Raghuwanshi, N., P. Kumari, A.K. Srivastava, P. Vashisth, T.C. Yadav, R. Prasad and V. Pruthi, 2017. Synergistic effects of Woodfordia fruticosa gold nanoparticles in preventing microbial adhesion and accelerating wound healing in Wistar albino rats in vivo. Mater. Sci. Eng.: C, 80: 252-262.
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  9. Raghuwanshi, N., A. Patel, N. Arora, R. Varshney, A.K. Srivastava and V. Pruthi, 2017. Antineoplastic and antimicrobial potential of novel phytofabricated silver nanoparticles from Pterospermum acerifolium leaf extract. Nanosci. Nanotechnol.-Asia, 7: 220-232.
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  10. Raghuvanshi, N., A. Pathak, A. Patel, P. Vashisth, H. Singh, A.K. Srivastava and V. Pruthi, 2017. Novel biogenic synthesis of silver nanoparticles and their therapeutic potential. Front. Biosci., 9: 33-43.
    PubMed  |  

  11. Gupta, S., N. Raghuwanshi, R. Varshney, I.M. Banat, A.K. Srivastava, P.A. Pruthi and V. Pruthi, 2017. Accelerated in vivo wound healing evaluation of microbial glycolipid containing ointment as a transdermal substitute. Biomed. Pharmacother., 94: 1186-1196.
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  12. Das, M.K., B.K. Prajapati, R.W. Tiendrebeogo, K. Ranjan and B. Adu et al., 2017. Malaria epidemiology in an area of stable transmission in tribal population of Jharkhand, India. Malar. J., Vol. 16. 10.1186/s12936-017-1833-9.
    CrossRef  |  Direct Link  |  

  13. Vashisth, P., A.K. Srivastava, H. Nagar, N. Raghuwanshi and S. Sharan et al., 2016. Drug functionalized microbial polysaccharide based nanofibers as transdermal substitute. Nanomed.: Nanotechnol. Biol. Med., 12: 1375-1385.
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  14. Sulakhiya, K., V.K. Patel, R. Saxena, J. Dashore, A.K. Srivastava and M. Rathore, 2016. Effect of beta vulgaris Linn. leaves extract on anxiety- and depressive-like behavior and oxidative stress in mice after acute restraint stress. Pharmacogn. Res., Vol. 8. .

  15. Srivastava, A.K., P. Khare, H.K. Nagar, N. Raghuwanshi and R. Srivastava, 2016. Hydroxyproline: A potential biochemical marker and its role in the pathogenesis of different diseases. Curr. Protein Pept. Sci., 17: 596-602.
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  16. Srivastava, A.K., H.K. Nagar, H.S. Chandel and M.S. Ranawat, 2016. Antipsoriatic activity of ethanolic extract of Woodfordia fruticosa (L.) Kurz flowers in a novel in vivo screening model. Indian J. Pharmacol., 48: 531-536.
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  17. Pathak, A., P.K. Singour, A.K. Srivastava, P. Gouda, S. Kumar and B.K. Goutam, 2016. Hansch analysis of novel acetamide derivatives as highly potent and specific MAO-A inhibitors. Cent. Nervous Syst. Agents Med. Chem., 16: 143-151.
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  18. Pathak, A., A.K. Srivastava, P.K. Singour and P. Gouda, 2016. Synthetic and natural monoamine oxidase inhibitors as potential lead compounds for effective therapeutics. Cent. Nervous Syst. Agents Med. Chem., 16: 81-97.
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  19. Nagar, H.K., A.K. Srivastava, R. Srivastava, M.L. Kurmi, H.S. Chandel and M.S. Ranawat, 2016. Pharmacological investigation of the wound healing activity of Cestrum nocturnum (L.) ointment in Wistar albino rats. J. Pharm., Vol. 2016. 10.1155/2016/9249040.
    CrossRef  |  Direct Link  |  

  20. Nagar, H.K., A.K. Srivastava, R. Srivastava and M.S. Ranawat, 2016. Evaluation of potent phytomedicine for treatment of psoriasis using UV radiation induced psoriasis in rats. Biomed. Pharmacother., 84: 1156-1162.
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  21. Deepa, C., R. Srivastava, A.K. Srivastava and A. Kotiya, 2016. Wound healing activity of hydro-alcoholic extract of Cinnamomum nitidum Blume (Lauraceae) in Wistar albino rats. Curr. Tradit. Med., 2: 134-145.
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  22. Srivastava, A.K., U.K. Patil, A. Singhai and M. Kumar, 2015. Anti-ulcer and antioxidant activity of nelumbo nucifera gaertn stalks in rats. Int. J. Pharm. Pharm. Sci., 7: 368-373.
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  23. Srivastava, A.K., A.S. Srivastava, H. Nagar, R. Srivastava, Deepa, G. Shukla, 2015. Phytopharmacological evaluation of aerial parts of Woodfordia fruticosa (L.) kurz in cough variant asthma. Pharmacogn. J., 7: 296-299 .

  24. Pathak, A., P.K. Singour, P. Gouda, A.K. Srivastava, S. Kumar and A. Pathak, 2015. Docking study of novel acetamide derivatives as specific MAO-A inhibitors. Am. J. PharmTech Res., 5: 190-209.
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  25. Nagar, H.K., H.S. Chandela, P. Rathorea, A.K. Srivastavab, G. Vishwakarmab, R. Srivastavac and M.S. Ranawatd, 2015. Curative effect of extractive phytoconstituents of psidium guajava leaves on ethylene glycol induced urolithiasis in experimental animals. MIT Int. J. Pharm. Sci., 1: 31-37.
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  26. Kumar, U., R. Sagar, A. Bhandari, A.K. Srivastava, 2015. Preliminary phytochemical screening and comparative In-vitro antioxidant studies of different extracts of Dipteracanthus prostratus nees. Int. J. Res. Dev. Pharm. Life Sci., 4: 1784-1790.

  27. Kumar, U., R. Sagar, A. Bhandari and A.K. Srivastava, 2015. Evaluation of anti-inflammatory activity of methanolic and toluene extract of Dipteracanthus prostratus nees. Int. J. Pharmacogn. Phytochem. Res., 7: 435-439.
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  28. Kumar, U., R. Sagar, A. Bhandari and A.K. Srivastava, 2015. Antihyperglycemic activity of Dipteracanthus prostratus nees and it's probable mechanism of action in streptozotocin induced diabetic rats. Int. J. Pharm. Sci. Res., Vol. 6. .

  29. Deepa, A. Lodhi, R. Srivastava, A.K. Srivastava and H. Nagar, 2015. Ameliorative effect of Jasminum grandiflorum (L.) leaves against cyclophosphamide induced renal and liver toxicity. MIT Int. J. Pharm. Sci., 1: 38-42.

  30. Bhatt, D.K., A.K. Jatav, S. Kiledar and A.K. Srivastava, 2015. Development and evaluation of physicochemical and nutritional properties of protein enriched fortified pulses pasta. IOSR J. Environ. Sci. Toxicol. Food Technol., 9: 62-67.
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  31. Thakur, N., P. Khare, A. Khan and A.K. Srivastava, 2014. Enhancement of oral bioavailability of irbesartan by niosomal formulation. Asian J. Pharm. Educ. Res., 3: 122-133.

  32. Srivastava, R., A.K.S. Deepa, P. Khare and H. Nagar, 2014. Parkinson's disease, its implication and treatment with special reference to liver x receptor: A review. World J. Pharm. Pharm. Sci., 3: 287-309.
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  33. Dubey, T., A.K. Srivastava, H. Nagar, B.K. Mishra and S.S. Mishra, 2014. Nephroprotective activity of nelumbo nucifera gaertn. roots, leaves and flowers in gentamicin induced nephrotoxicity. Asian J. Pharm. Educ. Res., 3: 134-151.