Dr. Janendra Kumar Batra
ProfessorDepartment of Biochemistry, Jamia Hamdard University, New Delhi, India
Highest Degree
Ph.D. in Medical Biochemistry from University of Delhi, Delhi, India
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Selected Publications
- Attery, A. and J.K. Batra, 2017. Mouse eosinophil associated ribonucleases: Mechanism of cytotoxic, antibacterial and antiparasitic activities. Int. J. Biol. Macromol., 94: 445-450.
Direct Link | - Zaidi, S., M.A. Haque, S. Ubaid ullah, A. Prakash and M.I. Hassan, et al., 2016. Denatured states of yeast cytochrome c induced by heat and guanidinium chloride are structurally and thermodynamically different. J. Biomol. Struct. Dyn., 2016: 1-16.
Direct Link | - Singh, A., S. Ubaid ullah and J.K. Batra, 2016. Functional role of putative critical residues in mycobacterium tuberculosis RNase P protein. Int. J. Biochem. Cell Biol., 78: 141-148.
Direct Link | - Singh, A., S. Ubaid Ullah, A.K. Ramteke and J.K. Batra, 2016. Influence of conformation of M. Tuberculosis RNase P protein subunit on its function. PloS one, .
Direct Link | - Singh, A., A.K. Ramteke, T. Afroz and J.K. Batra, 2016. Insight into the role of histidine in RNR motif of protein component of RNase P of M. tuberculosis in catalysis. IUBMB Life, 68: 178-189.
Direct Link | - Choudhary, S., A. Pardo, R. Rosinke, J.K. Batra, S. Barth and R.S. Verma, 2016. Targeting c-kit receptor in neuroblastomas and colorectal cancers using stem cell factor (SCF)-based recombinant bacterial toxins. Appl. Microbiol. Biotechnol., 100: 263-277.
Direct Link | - Yadav, S.K. and J.K. Batra, 2015. Ribotoxin restrictocin manifests anti-HIV-1 activity through its specific ribonuclease activity. Int. J. Biol. Macromol., 76: 58-62.
CrossRef | PubMed | Direct Link | - Yadav, K.S. and J.K. Batra, 2015. Mechanism of anti-HIV activity of ribosome inactivating protein, saporin. Protein Pept. Lett., 22: 497-503.
Direct Link | - Parijat, P. and J.K. Batra, 2015. Role of DnaK in HspR-HAIR interaction of mycobacterium tuberculosis. IUBMB Life, 67: 816-827.
Direct Link | - Haque, M.A., S. Ubaid Ullah, S. Zaidi, M.I. Hassan, A. Islam, J.K. Batra and F. Ahmad, 2015. Characterization of pre-molten globule state of yeast iso-1-cytochrome c and its deletants at pH 6.0 and 25° C. Int. J. Biol. Macromol., 72: 1406-1418.
Direct Link | - Ubaid-ullah, S., M.A. Haque, S. Zaidi, M.I. Hassan and A. Islam, et al., 2014. Effect of sequential deletion of extra N-terminal residues on the structure and stability of yeast iso-1-cytochrome-c. J. Biomol. Struct. Dyn., 32: 2005-2016.
Direct Link | - Haque, M.A., S. Zaidi, U. Shah, A. Prakash, M.I. Hassan, A. Islam, J.K. Batra and F. Ahmad, 2014. In vitro and in silico studies of urea-induced denaturation of yeast iso-1- cytochrome c and its deletants at pH 6.0 and 25°C. J. Biomol. Struct. Dyn., 23: 1-10.
- Chopra, A. and J.K. Batra, 2014. Antimicrobial activity of human eosinophil granule proteins. In: Eosinophils: Methods and Protocols. Walsh, Garry, M. (Ed.)., Springer, Newyork, pp: 267-281.
- Sikriwal, D., D. Seth, S. Parveen, A. Malik, S. Broor and J.K. Batra, 2012. An insertion in loop L7 of human eosinophil-derived neurotoxin is crucial for its antiviral activity. J. Cell. Biochem., 113: 3104-3112.
Direct Link | - Rath, P., P.K. Singh and J.K. Batra, 2012. Functional and structural characterization of helicobacter pylori ClpX: a molecular chaperone of Hsp100 family. Protein Pept. Lett., 19: 1263-1271.
Direct Link | - Malik, A. and J.K. Batra, 2012. Antimicrobial activity of human eosinophil granule proteins: involvement in host defence against pathogens. Crit. Rev. Microbiol., 38: 168-181.
Direct Link | - Kaur, I., S.K. Yadav, G. Hariprasad, R.C. Gupta, A. Srinivasan, J.K. Batra and M. Puri, 2012. Balsamin, a novel ribosome-inactivating protein from the seeds of Balsam apple Momordica balsamina. Amino Acids, 43: 973-981.
Direct Link | - Bajaj, D. and J.K. Batra, 2012. The C-terminus of ClpC1 of Mycobacterium tuberculosis is crucial for its oligomerization and function. PloS one, .
Direct Link | - Bajaj, D. and J.K. Batra, 2012. Heat shock proteins in Mycobacterium tuberculosis: Involvement in survival and virulence of the pathogen. In: Understanding tuberculosis: Deciphering the secret life of the bacilli. Pere Joan C., (Ed.)., In Tech Open Science Open Minds, Croatia, pp: 257-276.
- Singh, A. and J.K. Batra, 2011. Role of unique basic residues in cytotoxic, antibacterial and antiparasitic activities of human eosinophil cationic protein. Biol. Chem., 392: 337-346.
Direct Link | - Rehman, M.T., P. Dey, M.I. Hassan, F. Ahmad and J.K. Batra, 2011. Functional role of glutamine 28 and arginine 39 in double stranded RNA cleavage by human pancreatic ribonuclease. PloS one, .
Direct Link | - Tapryal, S., L. Krishnan, J.K. Batra, K.J. Kaur and D.M. Salunke, 2010. Cloning, expression and efficient refolding of carbohydrate-peptide mimicry recognizing single chain antibody 2D10. Protein Expression Purif., 72: 162-168.
Direct Link | - Sikriwal, D. and J.K. Batra, 2010. Ribosome inactivating proteins and apoptosis. In: Toxic Plant Proteins, Plant Cell Monograph. Lord, J.M. and M.R. Hartley, (Ed.)., Springer-Verlag Berlin Heidelberg, New York, pp: 167-190.
- Sikriwal, D., D. Seth and J.K. Batra, 2009. Role of catalytic and non-catalytic subsite residues in ribonuclease activity of human eosinophil-derived neurotoxin. Biol. Chem., 390: 225-234.
CrossRef | PubMed | Direct Link | - Choudhary, R.K. and J.K. Batra, 2009. Engineering antibodies for cancer therapy. Curr. Sci., 96: 1592-1600.
- Sikriwal, D., P. Ghosh and J.K. Batra, 2008. Ribosome inactivating protein saporin induces apoptosis through mitochondrial cascade, independent of translation inhibition. Int. J. Biochem. Cell Biol., 40: 2880-2888.
Direct Link | - Kar, N.P., D. Sikriwal, P. Rath, R.K. Choudhary and J.K. Batra, 2008. Mycobacterium tuberculosis ClpC1 characterization and role of the N-terminal domain in its function. FEBS J., 275: 6149-6158.
- Sikriwal, D., D. Seth, P. Dey and J.K. Batra, 2007. Human eosinophil-derived neurotoxin: Involvement of a putative non-catalytic phosphate-binding subsite in its catalysis. Mol. Cell Biochem., 303: 175-181.
CrossRef | PubMed | Direct Link | - Dey, P., M. Tripathi and J.K. Batra, 2007. Involvement of loops L2 and L4 of ribonucleolytic toxin restrictocin in its functional activity. Protein Pept. Lett., 14: 125-129.
Direct Link | - Dey, P., A. Islam, F. Ahmad and J.K. Batra, 2007. Role of unique basic residues of human pancreatic ribonuclease in its catalysis and structural stability. Biochem. Biophys. Res. Commun., 360: 809-814.
Direct Link | - Ghosh, P. and J.K. Batra, 2006. The differential catalytic activity of ribosome-inactivating proteins saporin 5 and 6 is due to a single substitution at position 162. Biochem. J., 400: 99-104.
Direct Link | - Gaur, D. and J.K. Batra, 2005. Role of aspartic acid 121 in human pancreatic ribonuclease catalysis. Mol. Cell. Biochem., 275: 95-101.
Direct Link | - Basu, S.K., J.K.Batra and D.M. Salunke, 2004. Deep roots, open skies: new biology in India. Narosa Publishing House, New Delhi, India, Pages: 200.
- Batra, J.K., 2003. The aspergillus ribotoxins. Appl. Genomics Proteomics, 2: 145-159.
- Bagga, S., M.V. Hosur and J.K. Batra, 2003. Cytotoxicity of ribosome-inactivating protein saporin is not mediated through α2-macroglobulin receptor. FEBS Lett., 541: 16-20.
Direct Link | - Bagga, S., D. Seth and J.K. Batra, 2003. The cytotoxic activity of ribosome-inactivating protein Saporin-6 is attributed to its rRNA N-glycosidase and internucleosomal DNA fragmentation activities. J. Biol. Chem., 278: 4813-4820.
CrossRef | PubMed | Direct Link | - Goyal, A., D. Seth and J.K. Batra, 2002. Role of cis prolines 112 and 126 in the functional activity of ribonucleolytic toxin restrictocin. Biochem. Biophys. Res. Commun., 295: 812-817.
Direct Link | - Gaur, D., D. Seth and J.K. Batra, 2002. Glycine 38 is crucial for the ribonucleolytic activity of human pancreatic ribonuclease on double-stranded RNA. Biochem. Biophy. Res. Commun., 297: 390-395.
CrossRef | PubMed | Direct Link | - Nayak, S.K., S. Bagga, D. Gaur, D.T. Nair, D.M. Salunke and J.K. Batra, 2001. Mechanism of specific target recognition and RNA hydrolysis by ribonucleolytic toxin restrictocin. Biochem., 40: 9115-9124.
Direct Link | - Gaur, D., S. Swaminathan and J.K. Batra, 2001. Interaction of human pancreatic ribonuclease with human ribonuclease inhibitor Generation of inhibitor-resistant cytotoxic variants. J. Biol. Chem., 276: 24978-24984.
Direct Link | - Nayak, S.K. and J.K. Batra, 2000. Localization of the catalytic activity in restrictocin molecule by deletion mutagenesis. Eur. J. Biochem., 267: 1777-1783.
Direct Link | - Goyal, A. and J.K. Batra, 2000. Inclusion of a furin-sensitive spacer enhances the cytotoxicity of ribotoxin restrictocin containing recombinant single-chain immunotoxins. Biochem. J., 345: 247-254.
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