Dr. Jayati Roy Choudhury

Research Scientist
University of Texas Medical Branch, USA

Highest Degree
Ph.D. in Chemistry from Wake Forest University, USA

My URL
https://livedna.org/91.1495

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Area of Interest:

Chemistry
Biochemistry
Molecular Biology
Organic Chemistry
Medicinal Chemistry

Selected Publications

  1. Carpio, R.V., T.D. Silverstein, S. Lone, M.K. Swan and J.R. Choudhury et al., 2009. Structure of human DNA polymerase κ inserting dATP opposite an 8-OxoG DNA lesion. Plos One., 4: e5766-e5766.
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  2. Zhidong, M., J.R. Choudhury, M.W. Wright, C.S. Day, G. Saluta, G.L. Kucera and U. Bierbach, 2008. A non-cross-linking platinum-acridine agent with potent activity in non-small-cell lung cancer. J. Med. Chem., 51: 7574-7580.
    CrossRef  |  PubMed  |  Direct Link  |  

  3. Choudhury, J.R., R. Guddneppanavar, G. Saluta, G.L. Kucera and U. Bierbach, 2008. Tuning the DNA conformational perturbations induced by cytotoxic platinum-acridine bisintercalators: Effect of metal cis/trans isomerism and DNA threading groups. J. Med. Chem., 51: 3069-3072.
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  4. Zhidong, M., J.R. Choudhury, G.L. Kucera, G. Saluta and U. Bierbach, 2007. Tuning the reactivity and DNA interactions of platinum-acridine hybrid agents. Proceedings of the 59th Southeast Regional Meeting of American Chemical Society, Greenville, SC, October 24-27..

  5. Guddneppanavar, R., J.R. Choudhury, A.R. Kheradi, B.D. Steen and G. Saluta et al., 2007. Effect of the diamine nonleaving group in platinum-acridinylthiourea conjugates on DNA damage and cytotoxicity. J. Med. Chem., 50: 2259-2263.
    CrossRef  |  PubMed  |  Direct Link  |  

  6. Choudhury, J.R., R. Guddneppanavar, G.L. Kucera, G. Saluta and U. Bierbach, 2007. DNA conformational changes induced by a highly charged, cytotoxic platinum-based bisintercalator. Proceedings of the 59th Southeast Regional Meeting of American Chemical Society, Greenville, SC, October 24-27..

  7. Choudhury, J.R., M.E. Budiman, R.W. Alexander and U. Bierbach, 2005. DNA sequence and groove recognition by platinum-acridine conjugates. Proceedings of the International Conference on Biological Inorganic Chemistry, Ann Arbor, MI, August 1-5..

  8. Choudhury, J.R. and U. Bierbach, 2005. Characterization of the bisintercalative DNA binding mode of a bifunctional platinum-acridine agent. Nucleic Acids Res., 33: 5622-5632.
    CrossRef  |  PubMed  |  Direct Link  |  

  9. Choudhury, J.R., M.E. Budiman, R.W. Alexander and U. Bierbach, 2004. DNA sequence and groove recognition by platinum-acridine conjugates. Proceedings of the 56th Southeast Regional Meeting of American Chemical Society, Raleigh, NC, November 3-5..
Member since June, 2010