Dr. Bhaswat Chakraborty

President/CEO/Company Owner
Cadila Pharmaceuticals Limited, India


Highest Degree
Ph.D. in Clinical Pharmacology from University of Saskatchewan, Canada

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Area of Interest:

Pharmacology and Toxicology
Clinical Pharmacology
Bianalytical Method Development
Biequivalence Trials
Pharmacy

Selected Publications

  1. Raja, C., N, Sagar, and C. Bhaswat, 2014. Recent insights into the association of chronic inflammatory andneurodegenerative processes in clinical depression. J. Funda. Pharma. Res, 2: 57-61.
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  2. Chakraborty B.S., 2014. Pharmacovigilance: curriculum and career. J. Adv. Pharm. Technol. Res, 5: 2-3.
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  3. Sakore, S., and B. Chakraborty, 2013. Formulation and evaluation of enalapril maleate sustained release matrix tablets. Int. J. Pharm. Biomed. Res, 4: 21-26.
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  4. Chakraborty, B.S., 2013. Critical issues in the conduct of antihypertensive clinical trials. J. Pharma. Sci. Tech, 2: 47-55.
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  5. Chakraborty, B.S., 2013. Clinical research in india: the current scenario and prospects. J. Adv. Pharm. Technol. Res, 4: 126-127.
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  6. Sakore, S., and B. Chakraborthy, 2012. IN-VITRO and in-vivo correlation of immediate release acyclovir tablet using wagner nelson method. Int. J. Phaema, 2: 598-604.
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  7. Ghosh, C., and B. Chakraborty, 2012. LC-MS Methods for Regulated Bioequivalence Studies: Do We Need to Worry about Matrix Effects? Omics Online Scientific Reports. Omics. Online. Sci. Rep, 1: 424-429.
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  8. Ghosh, C., V. Jha, C. Patra, R. Ahir and B. Chakraborty, 2012. SIMULTANEOUS determination of docosahexaenoic acid and eicosapentaenoic acid by lc-esi-ms/ms from human plasma. J. Liq. Chromatogr. Related Technol, 35: 1812-1825.
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  9. Ghosh, C., I. Jain, C.P. Shinde and B.S. Chakraborty, 2012. Rapid and sensitive liquid chromatography/tandem mass spectrometry method for simultaneous determination of enalapril and its major metabolite enalaprilat, in human plasma: Application to a bioequivalence study. Drug Test. Anal., 4: 94-103.
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  10. Ghosh, C., C.P. Shinde, and B. Chakraborty, 2012. Influence of ionization source design on matrix effects during lc-esi-ms/ms analysis. J. Chromatogr. B, 893: 193-200.
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  11. Kumar, A., R. Kachhadiya amd B.S. Chakraborty, 2011. Clinical outcome of patients of acute coronary syndrome at 7 and 30 days undergoing percutaneous coronary interventions and treated with bivalirudin and heparin. Int. J. Contemp. Res. Rev., 2: 31-35.

  12. Ghosh, C., and S. Gaur, C.P. Shinde, and B. Chakraborty, 2011. A systematic approach to overcome the matrix effect during lc-esi-ms/ms analysis by different sample extraction techniques. J. Bioequivalence Bioavailability, 3: 122-127.
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  13. Ghosh, C., V. Jha, C.P. Shinde and B.S. Chakraborty, 2011. A LC-MS analysis of acamprosate from human plasma: pharmacokinetic application. Drug Test. Anal., 3: 735-742.
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  14. Ghosh, C., S. Gaur, A. Singh, C.P. Shinde and B.S. Chakraborty, 2011. Estimation of nevirapine from human plasma by ESI-LC-MS/MS: A pharmacokinetic application. J. Bioequivalence Bioavailability, 3: 20-25.
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  15. Ghosh, C., I. Jain, S. Gaur, N. Patel, A. Upadhyay and B.S. Chakraborty, 2011. Simultaneous estimation of atorvastatin and its two metabolites from human plasma by ESI-LC-MS/MS. Drug Test. Anal., 3: 352-362.
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  16. Ghosh, C., A. Upadhayay, A. Singh, S. Bahadur, and B. S. Chakraborty,et al, 2011. SIMULTANEOUS determination of aspirin and its metabolite from human plasma by uplc-uv detection: application to pharmacokinetic study. J. Liq. Chromatogr. Related Technol, 34: 2326-2338.
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  17. Chakraborty, B.S., 2011. Clinical trials of antihypertensives: Nature of control and design. Indian J. Pharmacol., 43: 13-17.
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  18. Sharma, G.N., B.S. Chakraborty, J. Sanadya, U.S. Baghel, C. Ghosh and M. Singhal, 2010. Bio-analytical estimation of losartan and losartan carboxylic acid concentrations in human plasma by using LC-MS/MS. Int. J. Pharm. Qual. Assur., 2: 13-18.
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  19. Sakore, S., S. Kute, A. Tekade and B.S. Chakraborty, 2010. Long acting in situ gelling vehicle for ophthalmic delivery: A research. Int. J. Drug Formulation Res., 1: 324-348.

  20. Sakore, S., S. Chaudhary and B.S. Chakraborty, 2010. Biowaiver monograph for immediate release solid oral dosage forms: Ofloxacin. Int. J. Pharm. Pharm. Sci., 2: 156-161.
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  21. Patel, C.D., V.D. Modi, B.S. Chakraborty, N. Mathuria, P. Dadhaniya, P.A. Borade and P. Morankar, 2010. Effect of a novel antiinflammatory polyherbal preparation (Sudarshanam oil) on hematological parameters in Wistar rats. Acta Poloinae Pharm. Drug Res., 67: 277-281.
    PubMed  |  

  22. Patel, A., T. Shah, G. Shah, V. Jha and C. Ghosh et al., 2010. Preservation of bioavailability of ingredients and lack of drug-drug interactions in a novel five-ingredient polypill (Polycap ™). Am. J. Cardiovasc. Drugs, 10: 95-103.
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  23. Kute, S.D., S. Sakore and B.S. Chakraborty, 2010. Formulation approaches in ocular drug delivery system. Int. J. Pharm. Sci. Technol., 2: 118-145.
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  24. Kumar, A., R.K. Kachhadiya, V. Vaishnavi and B.S. Chakraborty, 2010. Comparison of tumor response rate and toxicities with polychemotherapy versus monochemotherapy in patients of metastatic breast cancer: A meta-analysis. Int. J. Curr. Res. Rev., 1: 1-9.

  25. Ghosh, C., V. Jha, R. Ahir, S. Shah, C.P. Shinde and B.S. Chakraborty, 2010. A rapid and most sensitive liquid chromatography/tandem mass spectrometry method for simultaneous determination of alverine and its major metabolite, para hydroxy alverine, in human plasma: Application to a pharmacokinetic and bioequivalence study. Drug Test. Anal., 2: 284-291.
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  26. Ghosh, C., C.P. Shinde and B.S. Chakraborty, 2010. Ionization polarity as a cause of matrix effects, its removal and estimation in ESI-LC-MS/MS bio-analysis. J. Anal. Bioanal. Tech., 1: 106-106.
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  27. Jain, S., V.V. Vaishnavi and B.S. Chakraborty, 2009. The effect of dyslipidemic drugs on mortality: A meta-analysis. Indian J. Pharmacol., 41: 4-8.
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  28. Ghosh, C., R.P. Singh, S. Inamdar, M. Mote and B.S. Chakraborty, 2009. Sensitive, selective, precise and accurate LC-MS method for determination of clonidine in human plasma. Chromatographia, 69: 1227-1232.
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  29. Gavali, D., K.S. Kulkarni, A. Kumar and B.S. Chakraborty, 2009. Therapeutic class specific signal detection of bradycardia associated with propranolol hydrochloride. Ind. J. Pharmacol., 41: 162-166.
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  30. Verma, R.J., B.S. Chakraborty, C. Patel and N. Mathuria, 2008. Curcumin ameliorates aflatoxin-induced changes in SDH and ATPase activities in liver and kidney of mice. Acta Poloinae Pharm. Drug Res., 65: 415-419.
    PubMed  |  

  31. Dadhaniya, P., C. Patel, M. Makwana, K. Vachhani, B.K. Gunale, A. Maseeh and B. Chakraborty, 2008. Safety assessment of tenatoprazole. Acute and subacute toxicity studies. Indian J. Clin. Pract., 19: 23-27.

  32. Pant, M.C., B.S. Chakraborty, N. Patel, S.S. Bisht and V.P. Verma et al., 2007. Role of Cadi-05 as an adjuvant therapy in advanced non small cell lung cancer: P3-022. J. Thoracic Oncol., 2: S616-S616.
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  33. Chakraborty, B.S., 2007. Cancer drug development-key regulatory considerations. Health Admin., 20: 29-36.
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  34. Gallicano, K.D., I.J. McGilveray, S. Qureshi, W. Nitchuk, and B. Chakraborty,et al, 1991. Comparative bioavailability of oral contraceptive products. Clin. Biochem, 24: 107-111.
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  35. Midha, K. K., B. S. Chakraborty, R. Schwede, E. M. Hawes, and G. McKay,et al, 1990. Comparative bioavailability of two tablet formulations of fluphenazine dihydrochloride in drug-free psychiatric patients. J. Pharm. Sci, 79: 3-8.
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  36. Midha KK1, G. McKay, B.S. Chakraborty, M.Young, and E.M.Hawes,et al, 1990. Bioequivalence of two thorazine tablet formulations using radioimmunoassay and gas chromatographic-mass spectrometric methods. J. Pharm. Sci, 79: 196-201.
    PubMed  |  

  37. Midha, K.K., B.S. Chakraborty, D.A. Ganes, M.M. Hawes, and J.W. Hubbard,et al, 1989. Intersubject variation in the pharmacokinetics of haloperidol and reduced haloperidol. J. Clin. Psychopharmacol, 9: 98-104.
    PubMed  |  

  38. Midha, K. K., B. S. Chakraborty, E. M. Hawes, J. W. Hubbard, and G. McKay,et al,, 1989. Comparative bioavailability of a new commercial tablet formulation and two lots of a reference formulation of haloperidol. J.Pharm.Sci, 78: 443-447.
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  39. Chakraborty, B.S., J. W. Hubbard, E. M. Hawes, G. McKay, and J. K. Cooper,et al, 1989. Interconversion between haloperidol and reduced haloperidol in healthy volunteers. Eur. J. Clin. Pharmacol, 37: 45-48.
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  40. Chakraborty, B. S., K. K. Midha, G. McKay, E. M. Hawes, and J. W. Hubbard,et al, 1989. Single dose kinetics of thioridazine and its two psychoactive metabolites in healthy humans: A dose proportionality study. J. Pharm. Sci, 78: 769-801.
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  41. Chakraborty, B.S., E.M. Hawes, G. McKay, J.W. Hubbard, and E.D. Korchinski,et al, 1988. S-OXIDATION of thioridazine to psychoactive metabolites: an oral dose-proportionality study in healthy volunteers. Drug. Metabol. Drug. Interact, 6: 425-438.
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  42. Chakraborty B.S., E.M. Hawes and K.K. Midha, 1988. Development of a radioimmunoassay procedure for sulforidazine and its comparison with a high-performance liquid chromatographic method. Ther. Drug. Monit, 10: 205-214.
    PubMed  |  

  43. Chakraborty, B.S., M. S. Sardessai, T. J. Jaworski, K. K. Midha and E. M. Hawes,et al., 1987. Synthesis and properties of haptens for the development of radioimmunoassays for thioridazine, mesoridazine, and sulforidazine. Pharma. Res, 4: 207-213.
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  44. Chakraborty, B.S., E.M. Hawes and K.K. Midha, 1987. Development of a radioimmunoassay procedure for mesoridazine and its comparison with a high-performance liquid chromatographic method. Ther. Drug. Monit, 9: 464-471.
    PubMed  |