Dr. Kasturi Mukhopadhyay

Professor
School of Environmental Sciences, India

Highest Degree
Ph.D. in Bio-Medical Physics from Saha Institute of Nuclear Physics, India

My URL
https://livedna.org/91.27381

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Area of Interest:

Biomedical Sciences
Environmental Microbiology
Anti-Microbial Properties
Animal Biodiversity
Environmental Biotechnology

Selected Publications

  1. Kumar, P., S.K. Kandi, S. Manohar, K. Mukhopadhyay and D.S. Rawat, 2019. Monocarbonyl curcuminoids with improved stability as antibacterial agents against Staphylococcus aureus and their mechanistic studies. ACS Omega, 4: 675-687.
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  2. Singh, M., T. Shireen and K. Mukhopadhyay, 2018. Susceptibility of clinical isolates of Staphylococcus aureus to alpha-melanocyte stimulating hormone and its in vivo efficacy. Am. J. Clin. Microbiol. Antimicrob., Vol. 1. .
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  3. Kumar, S., A. Kumar, M. Kaushal, P. Kumar, K. Mukhopadhyay and A. Kumar, 2018. Fungal-derived xenobiotic exhibits antibacterial and antibiofilm activity against Staphylococcus aureus. Drug Discover. Ther., 12: 214-223.
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  4. Joshi, S., S. Mumtaz, J. Singh, S. Pasha and K. Mukhopadhyay, 2018. Novel miniature membrane active lipopeptidomimetics against planktonic and biofilm embedded methicillin-resistant Staphylococcus aureus. Scient. Rep., Vol. 8. 10.1038/s41598-017-17234-z.
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  5. Santra, R.C., D. Ganguly, S. Jana, N. Banyal and J. Singh et al., 2017. Synthesizing a Cu II complex of tinidazole to tune the generation of the nitro radical anion in order to strike a balance between efficacy and toxic side effects. N. J. Chem., 41: 4879-4886.
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  6. Singh, J., S. Joshi, S. Mumtaz, N. Maurya and I. Ghosh et al., 2016. Enhanced cationic charge is a key factor in promoting staphylocidal activity of α-Melanocyte stimulating hormone via selective lipid affinity. Scient. Rep., Vol. 6. 10.1038/srep31492.
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  7. Tyagi, P., M. Singh, H. Kumari, A. Kumari and K. Mukhopadhyay, 2015. Bactericidal activity of curcumin I is associated with damaging of bacterial membrane. Plos One, Vol. 10. 10.1371/journal.pone.0121313.
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  8. Shireen, T., A. Basu, M. Sarkar and K. Mukhopadhyay, 2015. Lipid composition is an important determinant of antimicrobial activity of alpha-melanocyte stimulating hormone. Biophys. Chem., 196: 33-39.
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  9. Santra, R.C., D. Ganguly, J. Singh, K. Mukhopadhyay and S. Das, 2015. A study on the formation of the nitro radical anion by ornidazole and its significant decrease in a structurally characterized binuclear Cu(II)-complex: Impact in biology. Dalton Trans., 44: 1992-2000.

  10. Khatri, R., N. Akhtar, K. Mukhopadhyay, K.K. Verma, G. Sethuraman and A. Sharma, 2015. Genetic endowment of proinflammatory cytokine tumor necrosis factor‐α (–) 308 G> A polymorphism to Parthenium hysterophorus‐induced airborne contact dermatitis in an Indian cohort. Int. J. Dermatol., 54: 179-184.
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  11. Singh, M. and K. Mukhopadhyay, 2014. Alpha-melanocyte stimulating hormone: An emerging anti-inflammatory antimicrobial peptide. BioMed Res. Int., Vol. 2014. 10.1155/2014/874610.
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  12. Santra, R.C., K. Sengupta, R. Dey, T. Shireen and P. Das et al., 2014. X-ray crystal structure of a Cu(II) complex with the antiparasitic drug tinidazole, interaction with calf thymus DNA and evidence for antibacterial activity. J. Coordination Chem., 67: 265-285.
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  13. Singh, M., R. Gadepalli, B. Dhawan and K. Mukhopadhyay, 2013. Combination of alpha-melanocyte stimulating hormone with conventional antibiotics against methicillin resistant Staphylococcus aureus. PLoS One, Vol. 8. 10.1371/journal.pone.0073815.
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  14. Shireen, T., M. Singh, T. Das and K. Mukhopadhyay, 2013. Differential adaptive responses of Staphylococcus aureus to in vitro selection with different antimicrobial peptides. Antimicrob. Agents Chemother., 57: 5134-5137.
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  15. Shireen, T., M. Singh, B. Dhawan and K. Mukhopadhyay, 2012. Characterization of cell membrane parameters of clinical isolates of Staphylococcus aureus with varied susceptibility to alpha-melanocyte stimulating hormone. Peptides, 37: 334-339.
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  16. Singh, M. and K. Mukhopadhyay, 2011. C-terminal amino acids of alpha-melanocyte-stimulating hormone are requisite for its antibacterial activity against Staphylococcus aureus. Antimicrob. Agents Chemother., 55: 1920-1929.
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  17. Khatri, R., K. Mukhopadhyay, K.K. Verma, G. Sethuraman and A. Sharma, 2011. Genetic predisposition due to lower producers of IL-10 (-) 1082 G>A & (-) 819 C>T loci but no endowment due to IFN-g (+) 874 A>T locus to parthenium dermatitis in Indian cohort. Br. J. Dermatol., 165: 115-122.

  18. Shireen, T., S.K. Venugopal, D. Ghosh, R. Gadepalli, B. Dhawan and K. Mukhopadhyay, 2009. In vitro antimicrobial activity of alpha-melanocyte stimulating hormone against major human pathogen Staphylococcus aureus. Peptides, 30: 1627-1635.
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  19. Mukhopadhyay, K., W. Whitmire, Y.Q. Xiong, J. Molden and T. Jones et al., 2007. In vitro susceptibility of Staphylococcus aureus to thrombin-induced platelet microbicidal protein-1 (tPMP-1) is influenced by cell membrane phospholipid composition and asymmetry. Microbiology, 153: 1187-1197.
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  20. Bayer, A.S., L.I. Kupferwasser, M.H. Brown, R.A. Skurray and S. Grkovic et al., 2006. Low-level resistance of Staphylococcus aureus to thrombin-induced platelet microbicidal protein 1 in vitro associated with qacA gene carriage is independent of multidrug efflux pump activity. Antimicrob. Agents Chemother., 50: 2448-2454.
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  21. Xiong, Y.Q., K. Mukhopadhyay, M.R. Yeaman, J. Adler-Moore and A.S. Bayer, 2005. Functional interrelationships between cell membrane and cell wall in antimicrobial peptide-mediated killing of Staphylococcus aureus. Antimicrob. Agents Chemother., 49: 3114-3121.
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  22. Debnath, D.K., K. Mukhopadhyay and S. Basak, 2005. Acid-induced denaturation and refolding of prothrombin. Biophys. Chem., 116: 159-165.
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  23. Mukhopadhyay, K., T. Prasad, P. Saini, T.J. Pucadyil, A. Chattopadhyay and R. Prasad, 2004. Membrane sphingolipid-ergosterol interactions are important determinants of multidrug resistance in Candida albicans. Antimicrob. Agents Chemother., 48: 1778-1787.
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  24. Weinreb, G.E., K. Mukhopadhyay, R. Majumder and B.R. Lentz, 2003. Cooperative roles of factor Va and phosphatidylserine-containing membranes as cofactors in prothrombin activation. J. Biol. Chem., 278: 5679-5684.
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  25. Jha, S., N. Karnani, S.K. Dhar, K. Mukhopadhayay and S. Shukla et al., 2003. Purification and characterization of the N-terminal nucleotide binding domain of an ABC drug transporter of Candida albicans: Uncommon cysteine 193 of Walker A is critical for ATP hydrolysis. Biochemistry, 42: 10822-10832.
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  26. Mukhopadhyay, K., A. Kohli and R. Prasad, 2002. Drug susceptibilities of yeast cells are affected by membrane lipid composition. Antimicrob. Agents Chemother., 46: 3695-3705.
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  27. Kohli, A., N.F.N. Smriti, K. Mukhopadhyay, A. Rattan and R. Prasad, 2002. In vitro low-level resistance to azoles in Candida albicans is associated with changes in membrane lipid fluidity and asymmetry. Antimicrob. Agents Chemother., 46: 1046-1052.
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  28. Mondal, M., K. Mukhopadhyay, S. Basak and A. Chakrabarti, 2001. Effect of cholesterol on interaction of dibucaine with phospholipid vesicles: A fluorescence study. Biochim. Biophys. Acta (BBA)-Biomembranes, 1511: 146-155.
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  29. Mukhopadhyay, K. and S. Basak, 1998. Conformation induction in melanotropic peptides by trifluoroethanol: Fluorescence and circular dichroism study. Biophys. Chem., 74: 175-186.
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  30. Bhattacharyya, K. and S. Basak, 1995. Somatostatin in a water‐restricted environment: Fluorescence and circular dichroism study in AOT reverse micelles. Photochem. Photobiol., 62: 17-23.
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  31. Bhattacharyya, K. and S. Basak, 1993. Fluorescence study of melanocyte stimulating hormones in AOT reverse micelles. Biophys. Chem., 47: 21-31.
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  32. Dasgupta, D., P. Aich, R. Sen and K. Bhattacharyya, 1992. Characterization of interaction of an antitumor antibiotic, chromomycin A3, with synthetic DNA, poly(dG-dC):poly(dG-dC)-a spectroscopic study. Proc. Indian Natl. Sci. Acad., 58: 311-320.
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  33. Bhattacharyya, K. and S. Basak, 1991. Steady-state fluorescence studies of α-melanocyte stimulating hormone in reverse micelles. Indian J. Phys., 65B: 481-487.
Member since March, 2019