Dr. Sree Harsha

Assistant Professor
King Faisal University, Saudi Arabia

Highest Degree
Ph.D. in Pharmaceutics from Rajiv Gandhi University of Health Sciences, Bangalore, Karnataka, India

My URL
https://livedna.org/91.30441

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Area of Interest:

Biomedical Sciences
Pharmaceutical Drugs
Pharmaceutical Science
Drug Absorption
Pharmacokinetic

Selected Publications

  1. Venugopala, K.N., S. Chandrashekharappa, M. Pillay, S. Bhandary and M. Kandeel et al., 2019. Synthesis and structural elucidation of novel benzothiazole derivatives as anti-tubercular agents: In-silico screening for possible target identification. Med. Chem., 15: 311-326.
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  2. Venugopala, K.N., S. Chandrashekharappa, M. Pillay, H.H. Abdallah and F.M. Mahomoodally et al., 2019. Computational, crystallographic studies,cytotoxicity and anti-tubercular activity of substituted 7-methoxy-indolizine analogues. PloSne, Vol: 14. 10.1371/journal.pone.0217270.
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  3. Venugopala, K.N., M.A. Khedr, M. Pillay, S.K. Nayak and S. Chandrashekharappa et al., 2019. Benzothiazole analogs as potential anti-TB agents: Computational input and molecular dynamics. J. Biomol. Struct. Dyn., 37: 1830-1842.
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  4. Venugopala, K.N., C. Tratrat, S. Chandrashekharappa, M. Attimarad and N. Sreeharsha et al., 2019. Anti-tubercular potency and computationally-assessed drug-likeness and toxicology of diversely substituted indolizines. Indian J. Pharma. Educ. Res., 53: 545-552.
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  5. Tratrat, C., M. Haroun, I. Xenikakis, K. Liaras and E. Tsolaki et al., 2019. Design, synthesis, evaluation of antimicrobial activity and docking studies of new thiazole-based chalcones. Curr. Top. Med. Chem., 19: 356-375.
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  6. SreeHarsha, N., R.V. Ghorpade, A.M. Alzahrani, B.E. Al-Dhubiab and K.N. Venugopala, 2019. Immobilization studies of Candida antarctica lipase B on gallic acid resin-grafted magnetic iron oxide nanoparticles. Int. J. Nanomed., 14: 3235-3244.
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  7. SreeHarsha, N., J.G. Hiremath, S. Chilukuri, R.K. Aitha and B.E. Al-Dhubiab et al., 2019. An approach to enhance dissolution rate of tamoxifen citrate. BioMed Res. Int., Vol. 2019. 10.1155/2019/2161348.
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  8. SreeHarsha, N., J.G. Hiremath, R.K. Aitha, A.J. Domb and B.E. Al‐Dhubiab et al., 2019. Paclitaxel loaded poly (DL lactic acid co castor oil) 60: 40 with poloxamer‐F68 rod shape cylindrical nanoparticle preparation and in vitro cytotoxicity studies. Polym. Adv. Technol., 30: 2613-2622.
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  9. SreeHarsha, N., A. Shariff, Y.A. Shendkar, B.E. Al-Dhubiab and G. Meravanige, 2019. Development and evaluation of a (SEDDS) self-emulsifying drug delivery system for darifenacin hydrobromide. Indian J. Pharm. Educ. Res., 53: S204-S212.
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  10. Nagaraja, S.H., B.E. Al-Dhubiab, R.K. Tekade, K.N. Venugopala, R.V. Ghorpade, G. Meravanige and A. Alqadheeb, 2019. Novel preparation and effective delivery of mucoadeshive nanoparticles containing anti-diabetic drug. Indian J. Pharm. Educ. Res., 53: S43-S49.
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  11. Attimarad, M., V.K. Narayanswamy, B.E. Aldhubaib, N. SreeHarsha and A.B. Nair, 2019. Development of UV spectrophotometry methods for concurrent quantification of amlodipine and celecoxib by manipulation of ratio spectra in pure and pharmaceutical formulation. PLoS One, Vol. 14. 10.1371/journal.pone.0222526.
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  12. Nair, A.B., S. Gupta, B.E. Al-Dhubiab, S. Jacob and P. Shinu et al., 2019. Effective therapeutic delivery and bioavailability enhancement of pioglitazone using drug in adhesive transdermal patch. Pharmaceutics, Vol. 11. 10.3390/pharmaceutics11070359.
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  13. Sangi, S., N. SreeHarsha, A. Bawadekji and M. Al Ali, 2018. Chemotherapeutic drug targeting to lungs by way of microspheres after intravenous administration. Drug Des. Dev. Ther., 12: 3051-3060.
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  14. Nair, A.B., B.E. Al-Dhubiab, J. Shah, P. Vimal, M. Attimarad and S. Harsha, 2018. Development and evaluation of palonosetron loaded mucoadhesive buccal films. J. Drug Deliv. Sci. Technol., 47: 351-358.
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  15. Haroun, M., C. Tratrat, K. Kositzi, E. Tsolaki and A. Petrou et al., 2018. New benzothiazole-based thiazolidinones as potent antimicrobial agents. Design, synthesis and biological evaluation. Curr. Top. Med. Chem., 18: 75-87.
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  16. Chandrashekharappa, S., K.N. Venugopala, C. Tratrat, F.M. Mahomoodally and B.E. Aldhubiab et al., 2018. Efficient synthesis and characterization of novel indolizines: Exploration of in vitro COX-2 inhibitory activity and molecular modelling studies. New J. Chem., 42: 4893-4901.
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  17. Attimarad, M., S.H. Nagaraja, A.B. Nair, B.E. Aldhubaib and V.N. Katharigatta, 2018. Development of validated RP HPLC method with fluorescence detection for simultaneous quantification of sacubitril and valsartan from rat plasma. J. Liquid Chromatogr. Relat. Technol., 41: 246-252.
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  18. Asif, A.H., S. Harsha, N.H. Puttaswamy and B.E. Al-Dhubiab, 2018. An effective delivery system of sitagliptin using optimized mucoadhesive nanoparticles. Applied Sci., Vol. 8, No. 6. 10.3390/app8060861.
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  19. Nair, A.B., B.E. Al-Dhubiab, J. Shah, M. Attimarad and S. Harsha, 2017. Poly(lactic acid-co-glycolic acid) nanospheres improved the oral delivery of candesartan cilexetil. Indian J. Pharmaceut. Educ. Res., 51: 571-579.
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  20. Harsha, S., B.E. Al-Dhubiab, A.B. Nair, M. Attimarad, K.N. Venugopala and S.A. Kedarnath, 2017. Pharmacokinetics and tissue distribution of microspheres prepared by spray drying technique: Targeted drug delivery. Biomed. Res., 28: 3387-3396.
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  21. Attimarad, M., S.H. Nagaraja, B.E. Aldhubiab, A.B. Nair and K.N. Venugopala, 2017. Determination of vildagliptin in rat plasma by capillary electrophoresis tandem mass spectrometry: It’s application to pharmacokinetic study. Indian J. Pharm. Educ. Res., 51: 636-643.

  22. Al-Dhubiab, B.E., A.B. Nair, R. Kumria, M. Attimarad and S. Harsha, 2017. Development and evaluation of nebivolol hydrochloride nanocrystals impregnated buccal film. Farmacia, 67: 282-289.
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  23. Venugopala, K.N., G.D. Rao, S. Bhandary, M. Pillay and D. Chopra et al., 2016. Design, synthesis, and characterization of (1-(4-aryl)-1H-1,2,3-triazol-4-yl) methyl, substituted phenyl-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylates against Mycobacterium tuberculosis. Drug Des. Dev. Therapy, 10: 2681-2690.
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  24. Ramaiah, B., S.H. Nagaraja, U.G. Kapanigowda, P.R. Boggarapu and R. Subramanian, 2016. High azithromycin concentration in lungs by way of bovine serum albumin microspheres as targeted drug delivery: Lung targeting efficiency in albino mice. DARU J. Pharmaceut. Sci., Vol. 24. 10.1186/s40199-016-0153-x.
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  25. Ramaiah, B., S.H. Nagaraja, U.G. Kapanigowda and P.R. Boggarapu, 2016. Improved lung concentration of levofloxacin by targeted gelatin microspheres: In vivo pharmacokinetic evaluation of intake rate, targeting efficacy parameters and peak concentration ratio in albino mice. J. Pharm. Innov., 11: 289-299.
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  26. Nair, A.B., R. Kumria, B.E. Al-Dhubiab, M. Attimarad and S. Harsha, 2016. Development of transdermal delivery system of vildagliptin and its comparison with oral therapy. Indian J. Pharmaceut. Educ. Res., 50: 130-137.
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  27. Kapanigowda, U.G., S.H. Nagaraja, B. Ramaiah, P.R. Boggarapu and R. Subramanian, 2016. Enhanced trans-corneal permeability of valacyclovir by polymethacrylic acid copolymers based ocular microspheres: In vivo evaluation of estimated pharmacokinetic/pharmacodynamic indices and simulation of aqueous humor drug concentration-time profile. J. Pharmaceut. Innov., 11: 82-91.
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  28. Attimarad, M., S.H. Nagaraja, B.E. Al-Dhubaib, A.B. Nair and V.K. Narayanaswamy, 2016. Capillary electrophoresis: MEKC assay method for simultaneous determination of olmesartan medoxomil, amlodipine besylate and hydrochlorothiazide in tablets. Indian J. Pharm. Educ. Res., 50: S188-S195.

  29. Al-Dhubiab, B.E., A.B. Nair, R. Kumria, M. Attimarad and S. Harsha, 2016. Development and evaluation of buccal films impregnated with selegiline-loaded nanospheres. Drug Deliv., 23: 2154-2162.
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  30. Venugopala, K.N., R. Govender, M.A. Khedr, R. Venugopala, B.E. Aldhubiab, S. Harsha and B. Odhav, 2015. Design, synthesis and computational studies on dihydropyrimidine scaffolds as potential lipoxygenase inhibitors and cancer chemopreventive agents. Drug Des. Dev. Ther., 9: 911-921.
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  31. Nair, A.B., R. Kumria, B.E. Al-Dhubiab, M. Attimarad and S. Harsha, 2015. Noninvasive sampling of gabapentin by reverse iontophoresis. Pharm. Res., 32: 1417-1424.
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  32. Kapanigowda, U.G., S.H. Nagaraja, B. Ramaiah and P.R. Boggarapu, 2015. Improved intraocular bioavailability of ganciclovir by mucoadhesive polymer based ocular microspheres: Development and simulation process in Wistar rats. DARU J. Pharmaceut. Sci., Vol. 23. 10.1186/s40199-015-0132-7.
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  33. Harsha, S.N., B.E. Al-Dhubiab, A.B. Nair, I.A. Alhaider and M. Attimarad et al., 2015. Nanoparticle formulation by Büchi B-90 nano spray dryer for oral mucoadhesion. Drug Des. Dev. Ther., 9: 273-282.
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  34. Harsha, S., B.E. Al-Dhubiab, A.B. Nair, M. Al-Khars and M. Al-Hassan et al., 2015. Novel drying technology of microsphere and its evaluation for targeted drug delivery for lung. Drying Technol., 33: 502-512.
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  35. Harsha, N.S., 2015. In vitro and in vivo evaluation of nanoparticles prepared by nano spray drying for stomach mucoadhesive drug delivery. Drying Technol., 33: 1199-1209.
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  36. Al-Dhubiab, B.E., A.B. Nair, R. Kumria, M. Attimarad and S. Harsha, 2015. Formulation and evaluation of nano based drug delivery system for the buccal delivery of acyclovir. Colloids Surf B: Biointerfaces, 136: 878-884.
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  37. Nair, A.B., M. Attimarad, B.E. Al-Dhubiab, J. Wadhwa, S. Harsha and M. Ahmed, 2014. Enhanced oral bioavailability of acyclovir by inclusion complex using hydroxypropyl-β-cyclodextrin. Drug Delivery, 21: 540-547.
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  38. Harsha, S., M. Al-Khars, M. Al-Hassan, N.P. Kumar, A.B. Nair, M. Attimarad and B.E. Al-Dhubiab, 2014. Pharmacokinetics and tissue distribution of spray-dried carboplatin microspheres: Lung targeting via intravenous route. Arch. Pharmacal Res., 37: 352-360.
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  39. Attimarad, M., S.H. Nagaraja, B.E. Aldhubaib, A. Nair and K.N. Venugopala, 2014. Simultaneous determination of metformin and three gliptins in pharmaceutical formulations using RP HPLC: Application to stability studies on Linagliptin tablet formulation. Indian J. Pharmaceut. Educ. Res., 48: 45-53.
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  40. Attimarad, M., S.H. Nagaraja, B.E. Aldhubaib and A. Al-Najjar, 2014. Development of a rapid RP-HPLC method for simultaneous determination of metformin and vildagliptin in formulation and human plasma. J. Young Pharmacists, 6: 40-46.
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  41. Nair, A.B., K. Singh, P. Shinu, S. Harsha and B.E. Al-Dhubiab, 2013. A comprehensive study to evaluate the effect of constant low voltage iontophoresis on transungual delivery. Drug Dev. Ind. Pharm., 39: 807-815.
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  42. Nair, A.B., K. Singh, B.E. Al-Dhubiab, M. Attimarad, S. Harsha and I.A. Alhaider, 2013. Skin uptake and clearance of ciclopirox following topical application Biopharm. Drug Dispos., 34: 540-549.
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  43. Nair, A., S. Jacob, B. Al-Dhubiab, M. Attimarad and S. Harsha, 2013. Basic considerations in the dermatokinetics of topical formulations. Braz. J. Pharm. Sci., 49: 423-434.
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  44. Mansour, S.W., S. Sangi, S. Harsha, M.A. Khaleel and A.R.N. Ibrahim, 2013. Sensibility of male rats fertility against olive oil, Nigella sativa oil and pomegranate extract. Asian Pac. J. Trop. Biomed., 3: 563-568.
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  45. Harsha, S., M. Attimard, T.A. Khan, A.B. Nair, B.E. Aldhubiab, S. Sangi and A. Shariff, 2013. Design and formulation of mucoadhesive microspheres of sitagliptin. J. Microencapsul., 30: 257-264.
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  46. Harsha, S., 2013. Pharmaceutical suspension containing both immediate/sustained-release amoxicillin-loaded gelatin nanoparticles: Preparation and in vitro characterization. Drug Des. Dev. Ther., 7: 1027-1033.
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  47. Harsha, N., B.E. Aldhubiab, I.A. Alhaider, M. Attimarad and A. Nair, 2013. Carbopol 934-P loaded with vildagliptin for diabetic delivery: In vitro and in vivo evaluation of nanoparticles. Curr. Nanosci., 9: 642-647.
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  48. Ghosh, B., D. Iyer, A.B. Nair and N.S. Harsha, 2013. Prospects of iontophoresis in cardiovascular drug delivery. J. Basic Clin. Pharm., 4: 25-30.
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  49. Baby, B., N.S. Harsha, K.N. Jayaveera and A. Abraham, 2013. Formulation and evaluation of a robust drug delivery system by using levofloxacin-chitosan/hydroxypropyl β-cyclodextrin nanoparticles. Drug Deliv. Lett., 3: 12-17.
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  50. Sangi, S., M. Al Turki, G.A. Otaibi, M.A.K. Al Hazoom and S. Harsha, 2012. Analysis and evaluation of prescriptions in Al-Ahsa (Saudi Arabia). Ars Pharmaceut., 53: 28-31.
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  51. Nair, A.B., R. Kumria, S. Harsha, M. Attimarad, B.E. Al-Dhubiab and I.A. Alhaider, 2012. In vitro techniques to evaluate buccal films. J. Controll. Release, 166: 10-21.
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  52. Kathiravan, G., S.M. Sureban, H.N. Sree, V. Bhuvaneshwari and E. Kramony, 2012. Isolation of anticancer drug TAXOL from Pestalotiopsis breviseta with apoptosis and B-cell lymphoma protein docking studies. J. Basic Clin. Pharm., 4: 14-19.
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  53. Harsha, S., 2012. Dual drug delivery system for targeting H. pylori in the stomach: Preparation and in vitro characterization of amoxicillin-loaded Carbopol® nanospheres. Int. J. Nanomed., 7: 4787-4796.
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  54. Harsha, S. and S.M. Sureban, 2012. Journal of basic and clinical pharmacy signs collaboration agreement with medknow publications-wolters kluwer health. J. Basic Clin. Pharm., 3: 329-329.
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  55. Baby, B., N.S. Harsha, K.N. Jayaveera and A. Abraham, 2012. Formulation and evaluation of levofloxacin nanoparticles by ionic gelation method. Res. Rev. J. Pharm. Pharm. Sci., 1: 7-15.

  56. Baby, B., N.S. Harsha, K.N. Jayaveera and A. Abraham, 2012. Determination of process variables using factorial design on entrapment efficiency of levofloxacin nanoparticles. J. Pharm. Chem., 6: 3-7.

  57. Attimarad, M.V., N.S. Harsha and R.S. Setty, 2012. Simultaneous determination of ofloxacin and flavoxate hydrochloride in human plasma by RP HPLC. J. Liquid Chromatogr. Relat. Technol., 35: 768-777.
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  58. Attimarad, M., B.E. Al-Dhubiab, I.A. Alhaider, A.B. Nair, N.S. Harsha and K.M. Ahmed, 2012. Simultaneous determination of moxifloxacin and cefixime by first and ratio first derivative ultraviolet spectrophotometry. Chem. Cent. J., Vol. 6. 10.1186/1752-153X-6-105.
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  59. Sangi, S., S. Harsha, S. Tasleem-ur-Rasool and A.H. Asif, 2011. Formulation and evaluation of mucoadhesive Nigalla sativa and olive oils for vaginal infections. Der Pharm. Lett., 3: 39-46.
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  60. Attimarad, M., K.K.M. Ahmed, B.E. Aldhubaib and S. Harsha, 2011. High-performance thin layer chromatography: A powerful analytical technique in pharmaceutical drug discovery. Pharmaceut. Methods, 2: 71-75.
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  61. Usha, G.K., R. Balakeshwa, N.S. Harsha, Rajarajan and K. Ramesh, 2010. A review of pharmacoepidemiological methods: Intensive hospital monitoring and medical record linkage. PharmacologyOnline, 1: 1145-1154.

  62. Kumar, V.S., R.H.S. Rani and N.S. Harsha, 2010. High-performance liquid chromatographic determination of plasma theophylline levels in the presence of caffeine and dietary xanthine metabolites. Arch. Pharmaceut. Sci. Res., 2: 274-282.
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  63. Mahalingan, K., S. Rajarajan, B. Baby and N.S. Harsha, 2009. Formulation and evaluation of clarithromycin extended release tablets. J. Pharmaceut. Sci. Res., 1: 97-100.
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  64. Harsha, S., R. Chandramouli and S. Rani, 2009. Ofloxacin targeting to lungs by way of microspheres. Int. J. Pharmaceut., 380: 127-132.
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  65. Harsha, S. and M.S. Al-Wesali, 2009. Preparation and evaluation of nanospheres for lung targeting. Int. J. Nano Biomater., 2: 143-146.
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  66. Harsha, N.S., S. Rajarajan, R. Chandramouli, S. Srinivasan and S. Rani, 2009. Preparation and Evaluation of Gentamicin Biodegradable Polymeric microspheres. Arch. Pharmaceut. Sci. Res., 1: 81-88.

  67. Harsha, N.S., G.S. Kumar, M.S. Al-Wesali, S.T. Rasool and F.A.S. Ibrahim, 2009. Exploring the anti-leishmanial activity of Phoenix dactylifera (date palm). Pharmacologyonline, 3: 791-799.
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  68. Harsha, N.S. and R.S. Rani, 2006. Drug targeting to lungs by way of microspheres. Arch. Pharmacal Res., 29: 598-604.
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  69. Bhaskaran, S. and S. Harsha, 2001. Hydrodynamic oral floating controlled delivery of diltiazem hydrochloride. Eastern Pharmacist, 44: 105-108.

  70. Bhaskaran, S. and S.N. Harsha, 2000. Effect of permeation enhancer and lontophoresis on permeation of atenolol from transdermal gels. Indian J. Pharmaceut. Sci., 62: 424-426.
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Member since September, 2019