Dr. Sridevi Chigurupati

Assistant Professor
Qassim University, Saudi Arabia


Highest Degree
Ph.D. in Pharmaceutical Sciences from Jawaharlal Nehru Technological University, Hyderabad, India

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Area of Interest:

Biomedical Sciences
Pharmacy
Medicinal Chemistry
Antioxidant Activities
Pharmaceutical Chemistry

Selected Publications

  1. Taha, M., T. Noreen, S. Imran, F. Nawaz and S. Chigurupati et al., 2019. Synthesis, α-amylase inhibition and molecular docking study of bisindolylmethane sulfonamide derivatives. Med. Chem. Res., 28: 2010-2022.
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  2. Taha, M., M. Irshad, S. Imran, F. Rahim and M. Selvaraj et al., 2019. Thiazole based carbohydrazide derivatives as α-amylase inhibitor and their molecular docking study. Heteroatom Chem., Vol. 2019. 10.1155/2019/7502347.
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  3. Salar, U., K.M. Khan, S. Chigurupati, S. Syed and S. Vijayabalan et al., 2019. New hybrid scaffolds based on hydrazinyl thiazole substituted coumarin; As novel leads of dual potential; In vitro α-amylase inhibitory and antioxidant (DPPH and ABTS radical scavenging) activities. Med. Chem., 15: 87-101.
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  4. Rafique, R., K.M. Khan, S. Chigurupati, A. Wadood and A.U. Rehman et al., 2019. Synthesis of new indazole based dual inhibitors of α-glucosidase and α-amylase enzymes, their in vitro, in silico and kinetics studies. Bioorg. Chem., (In Press). 10.1016/j.bioorg.2019.103195.
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  5. Karunanidhi, A., E. Ghaznavi-Rad, J.J. Nathan, N. Joseph and S. Chigurupati et al., 2019. Bioactive 2-(methyldithio) pyridine-3-carbonitrile from Persian shallot (Allium stipitatum Regel.) exerts broad-spectrum antimicrobial activity. Molecules, Vol. 24. 10.3390/molecules24061003.
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  6. Hameed, S., F. Seraj, R. Rafique, S. Chigurupati and A. Wadood et al., 2019. Synthesis of benzotriazoles derivatives and their dual potential as α-amylase and α-glucosidase inhibitors in vitro: Structure-activity relationship, molecular docking and kinetic studies. Eur. J. Med. Chem., Vol. 183. 10.1016/j.ejmech.2019.111677.
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  7. Chigurupati, S., V. Shantini, K.S. Kesavanarayanan, E.H. Nadia, M. Vasudevan, S.A. Eiman and D. Suprava, 2019. Identification of Nephelium lappaceum leaves phenolic and flavonoid component with radical scavenging, antidiabetic and antibacterial potential. Indian J. Tradit. Knowl., 18: 360-365.
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  8. Chigurupati, S., S.N. Sitansu, K.Y. Dong, K.S. Kesavanarayanan, A.S. Sohrab, I.M. Jahidul and R.N. Appala, 2019. Inhibitory activities of α-glucosidase and α-amylase and their hypoglycaemic capability in the treatment of diabetes. EC Pharmacol. Toxicol., 7: 79-91.

  9. Chigurupati, S., S. Vijayabalan, K.K. Selvarajan, M. Aldubayan, A. Alhowail, V. Mani and S. Das, 2019. Antimicrobial exploration between counterpart endosymbiont and host plant (Tamarindus indica Linn.). Curr. Pharm. Biotechnol., (In Press). 10.2174/1389201020666191028105325.
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  10. Yousuf, S., K.M. Khan, U. Salar, S. Chigurupati and M.T. Muhammad et al., 2018. 2’-Aryl and 4’-arylidene substituted pyrazolones: As potential α-amylase inhibitors. Eur. J. Med. Chem., 159: 47-58.
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  11. Wang, D., C. Ozen, I.M. Abu-Reidah, S. Chigurupati and J.K. Patra et al., 2018. Vasculoprotective effects of pomegranate (Punica granatum L.). Front. Pharmacol., Vol. 9. 10.3389/fphar.2018.00544.
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  12. Taha, M., M.S. Baharudin, N.H. Ismail, S. Imran and M.N. Khan et al., 2018. Synthesis, α-amylase inhibitory potential and molecular docking study of indole derivatives. Bioorg Chem., 80: 36-42.
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  13. Khan, M., A. Alam, K.M. Khan, U. Salar and S. Chigurupati et al., 2018. Flurbiprofen derivatives as novel α-amylase inhibitors: Biology-oriented drug synthesis (BIODS), in vitro and in silico evaluation. Bioorg. Chem., 81: 157-167.
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  14. Karunanidhi, A., E. Ghaznavi-Rad, R.A. Hamat, M.R. Pichika and L.T. Lung et al., 2018. Antibacterial and antibiofilm activities of nonpolar extracts of Allium stipitatum Regel. against multidrug resistant bacteria. BioMed Res. Int., Vol. 2018. 10.1155/2018/9845075.
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  15. Chigurupati, S., M.R. Marri, S. Vijayabalan and Selvarajan, 2018. Bacterial endo-symbiont inhabiting Durio zibethinus leaves and their antibacterial potential. Int. J. PharmTech Res., 11: 198-205.
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  16. Chigurupati, S., M. Selvaraj, V. Mani, J.I. Mohammad and K.K. Selvarajan et al., 2018. Synthesis of azomethines derived from cinnamaldehyde and vanillin: In vitro aetylcholinesterase inhibitory, antioxidant and insilico molecular docking studies. Med. Chem. Res., 27: 807-816.
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  17. Chigurupati, S., E.W.K. Yiik, J.I. Mohammad, S. Vijayabalan, K.K. Selvarajan and S.S. Nanda, 2018. Screening antimicrobial potential for Malaysian originated Tamarindus indica ethanolic leaves extract. Asian J. Pharm. Clin. Res., 11: 361-363.
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  18. Bale, A.T., K.M. Khan, U. Salar, S. Chigurupati and T. Fasina et al., 2018. Chalcones and bis-chalcones: As potential α-amylase inhibitors; synthesis, in vitro screening and molecular modelling studies. Bioorg. Chem., 79: 179-189.
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  19. Al-Arifi, A.A., A. Kumar, S. Chigurupati, M. Jawed and T. Pandurangan, 2018. Pretreatment variations in haematological parameters of breast cancer patients. Int. J. Pharm. Pharm. Sci., 10: 157-161.
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  20. Adegboye, A.A., K.M. Khan, U. Salar, S.A. Aboaba and S. Chigurupati et al., 2018. 2-Aryl benzimidazoles: Synthesis, in vitro α-amylase inhibitory activity and molecular docking study. Eur. J. Med. Chem., 150: 248-260.
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  21. Taha, M., S.A.A. Shah, S. Imran, M. Afifi and S. Chigurupati et al., 2017. Synthesis and in vitro study of benzofuran hydrazone derivatives as novel alpha-amylase inhibitor. Bioorg. Chem., 75: 78-85.
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  22. Taha, M., S. Imran, N.H. Ismail, M. Selvaraj and F. Rahim et al., 2017. Biology-oriented drug synthesis (BIODS) of 2-(2-methyl-5-nitro-1H-imidazol-1-yl) ethyl aryl ether derivatives, in vitro α-amylase inhibitory activity and in silico studies. Bioorg. Chem., 74: 1-9.
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  23. Taha, M., M.T. Javid, S. Imran, M. Selvaraj and S. Chigurupati et al., 2017. Synthesis and study of the α-amylase inhibitory potential of thiadiazole quinoline derivatives. Bioorg. Chem., 74: 179-186.
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  24. Taha, M., M. Irshad, S. Imran, S. Chigurupati anbd M. Selvaraj et al., 2017. Synthesis of piperazine sulfonamide analogs as diabetic-II inhibitors and their molecular docking study. Eur. J. Med. Chem., 141: 530-537.
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  25. Salar, U., K.M. Khan, S. Chigurupati, M. Taha and A. Wadood et al., 2017. New hybrid hydrazinyl thiazole substituted chromones: As potential α-amylase inhibitors and radical (DPPH & ABTS) scavengers. Scient. Rep., Vol. 7. 10.1038/s41598-017-17261-w.
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  26. Perumal, P., M. Vasudevan, C. Sridevi and M. Selvaraj, 2017. Anticholinesterase activity of octa peptides related to human histatin 8: In-silico drug design and in-vitro. Asian J. Pharm. Clin. Res., 10: 115-117.
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  27. Noreen, T., M. Taha, S. Imran, S. Chigurupati and F. Rahim et al., 2017. Synthesis of alpha amylase inhibitors based on privileged indole scaffold. Bioorg. Chem., 72: 248-255.
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  28. Mohammad, J.I., S. Chigurupati, O.A. Shahril and M.Z. Iqbal, 2017. Diabetic nephropathy an obvious complication in long term type-1 diabetes mellitus: A case study. Asian J. Pharm. Clin. Res., 10: 4-7.

  29. Mohammad, J.I., S. Chigurupati, M.K.A. Mallik and H. Noor, 2017. A case study on anion gap metabolic acidosis secondary to diabetes ketoacidosis. J. Innov. Pharm. Sci., 1: 58-59.

  30. Imran, S., M. Taha, M. Selvaraj, N.H. Ismail, S. Chigurupati and J.I. Mohammad, 2017. Synthesis and biological evaluation of indole derivatives as α-amylase inhibitor. Bioorg. Chem., 73: 121-127.
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  31. Das, S., M.T. Thuwin, S. Deborah, G. Lubnashirin, M.S. Kabir and S. Chigurupati, 2017. A prospective clinicaltrial of amlodipine in comparison to perindopril. Int. J. Pharm. Pharm. Sci., 9: 268-270.
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  32. Chigurupati, S., S.A. Shaikh, J.I. Mohammad, K.K. Selvarajan and A.R. Nemala et al., 2017. In vitro antioxidant and in vivo antidepressant activity of green synthesized azomethine derivatives of cinnamaldehyde. Indian J. Pharmacol., 49: 229-235.
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  33. Chigurupati, S., S. Muralidharan, L.S. Cin, W.Y. Raser, K. Santhi and K.S. Kesavanarayanan, 2017. Studying newly synthesized and developed 4-hydroxy-3-methoxybenzaldehyde schiff bases by UV spectrophotometry and high performance liquid chromatography. Pharm. Chem. J., 50: 789-794.
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  34. Chigurupati, S., R.N. Appala, K.K. Selvarajan, C.H. Khaw, C.F. Teoh, L. Batumanathan and J.I. Mohammad, 2017.. LC method development and validation for the determination of ropivacaine hydrochloride in bulk drug and pharmaceutical formulations. Pharm. Chem. J., 51: 71-80.
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  35. Chigurupati, S., J.I. Mohammad, S. Vijayabalan, N.D. Vaipuri, K.K. Selvarajan and A.R. Nemala, 2017. Quantitative estimation and antimicrobial potential of ethanol extract of Durio zibethinus Murr. leaves. Asian J. Pharm. Clin. Res., 10: 251-254.

  36. Chigurupati, S., N.K. Fuloria, S. Fuloria, S. Karupiah and R. Veerasamy et al., 2016. Synthesis and antibacterial profile of novel azomethine derivatives of β-phenylacrolein moiety. Trop. J. Pharm. Res., 15: 821-826.
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  37. Chigurupati, S., M. Selvaraj, V. Mani, K.K. Selvarajan and J.I. Mohammad et al., 2016. Identification of novel acetylcholinesterase inhibitors: Indolopyrazoline derivatives and molecular docking studies. Bioorg. Chem., 67: 9-16.
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  38. Chigurupati, S., 2016. Search for novel compounds as acrolein scavengers. AIMST Bull., 2: 10-10.

  39. Chigurupati, S., 2016. Xanthones scaffolds from nature (Garcinia). AIMST Bull., 2: 20-20.

  40. Bera, H. and S. Chigurupati, 2016. Recent discovery of non-nucleobase thymidine phosphorylase inhibitors targeting cancer. Eur. J. Med. Chem., 124: 992-1003.
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  41. Appala, R.N., S. Chigurupati, R.V.V.S.S. Appala, K.K. Selvarajan and J.I. Mohammad, 2016. A simple HPLC-UV method for the determination of glutathione in PC-12 cells. Scientifica, Vol. 2016. 10.1155/2016/6897890.
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  42. Veerasamy, R., S. Chigurupati, S. Sivadasan, D.S. Arumugam, H. Rajak and S.K. Krishnan, 2015. Exploring the relationship between the physico-chemical parameters and anti-tubercular activity of quinoline-3-carboxylic acids: A QSAR approach. Med. Chem. Res., 24: 744-752.
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  43. Chigurupati, S., S.A. Dhanaraj and P. Balakumar, 2015. A step ahead of PPARγ full agonists to PPARγ partial agonists: Therapeutic perspectives in the management of diabetic insulin resistance. Eur. J. Pharmacol., 755: 50-57.
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  44. Chigurupati, S., 2015. Designing new vanillin schiff bases and their antibacterial studies. J. Med. Bioeng., 4: 363-366.

  45. Sivadasan, S., A.N. Ali, K. Marimuthu, Z.A. Nazer, S. Chigurupati and R. Veerasamy, 2014. Menstrual disorders among students-An overview. Res. J. Pharm. Technol., 7: 704-711.

  46. Santhi, K., S.A. Dhanaraj, S. Chigurupati and S. Muralidharan, 2014. Therapeutic significance of polymeric nano particles as carriers for sustained ocular therapy: An overview. Res. J. Pharm. Biol. Chem. Sci., 5: 553-560.

  47. Chigurupati, S., R. Veerasamy, A.R. Nemala, A. Gowlikar and K.S. Lee, 2014. Designing and in-vitro antibacterial activity of new benzotriazole compounds. World J. Pharm. Pharm. Sci., 3: 1645-1651.

  48. Sridevi, C., M.M. Kannan and G. Abhinayani, 2013. Designing and biological evaluation of new benzimidazole compounds. Chem. Sci. Trans., 2: 922-926.

  49. Sridevi, C., K. Balaji and A. Naidu, 2011. Synthesis and pharmacological evaluation of some phenylpyrazolo indoquinoxaline derivatives. J. Chem., 8: 924-930.
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  50. Sridevi, C., K. Balaji, A. Naidu and R. Sudhakaran, 2010. Synthesis of some phenylpyrazolo benzimidazolo quinoxaline derivatives as potent antimicrobial agents. J. Chem. Pharm. Sci., 3: 13-16.

  51. Sridevi, C., K. Balaji, A. Naidu and R. Sudhakaran, 2010. Synthesis of some phenylpyrazolo benzimidazolo quinoxaline derivatives as potent antihistaminic agents. J. Chem., 7: 234-238.
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  52. Sridevi, C., K. Balaji, A. Naidu, S. Kavimani, D. Venkappayya, R. Suthakaran and S. Parimala, 2009. Synthesis of some phenylpyrazolo benzothiazolo quinoxaline derivatives. Int. J. PharmTech Res., 1: 816-821.

  53. Sridevi, C., K. Balaji, A. Naidu and R. Sudhakaran, 2009. Synthesis of some phenylpyrazolo benzimidazolo quinoxaline derivatives. Orient. J. Chem., 25: 325-328.

  54. Sridevi, C., K. Balaji, A. Naidu and R. Sudhakaran, 2009. Antioxidant, anti-inflammatory and histaminic activities of some phenyl pyrazolo benzothiazolo quinoxaline derivatives. J. Chem. Sci., 7: 1117-1126.

  55. Sridevi, C., K. Balaji, A. Naidu and R. Sudhakaran, 2009. Antioxidant and antiinflammatory activity of some phenylpyrazolo benzimidazolo quinoxaline derivatives. J. Pharm. Res., 2: 1500-1503.

  56. Sridevi, C., K. Balaji, A. Naidu and R. Sudhakaran, 2009. Antimicrobial evaluation and synthesis of some phenylpyrazolo benzothiazolo quinoxaline derivatives. J. Chem., 6: 866-870.
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  57. Parimala, S., G. Shashidhar, C. Sridevi, V. Jyothi and R. Suthakaran, 2009. Anti-inflammatory activity of Celastrus paniculatus seeds. Int. J. Pharm. Technol. Res., 1: 1326-1329.
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  58. Suthakaran, R., M.B. Raju, S. Kavimani, P. Venkappayya, R. Kumar and C.S.C.R.K. Suganthi, 2008. Synthesis, antioxidant, anti-inflammatory anti-microbial activity of 2-[(5-substituted aryl-1’n-substituted aryl amino methyl)pyrazol-3-yl] benzofuran. Rasayan J. Chem., 1: 39-45.
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  59. Sridevi, C., K. Balaji, A. Naidu and R. Sudhakaran, 2008. Synthesis and biological evaluation of some indoquinoxaline pyrazolines. Rasayan J. Chem., 1: 306-314.
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  60. Suthakaran, R., G. Somasekhar, C. Sridevi, M. Marikannan, K. Suganthi and G. Nagarajan, 2007. Synthesis, antiinflammatory, antioxidant and antibacterial activities of 7-methoxy benzofuran pyrazoline derivatives. Asian J. Chem., 19: 3353-3362.

  61. Jessy, E.M., A.T. Sambanthan, J. Alex, C.H. Sridevi and K.K. Srinivasan, 2007. Synthesis and biological evaluation of some novel quinazolones. Indian J. Pharm. Sci., 69: 476-478.
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  62. Babu, V.H., C. Sridevi, A. Joseph and K.K. Srinivasan, 2007. Synthesis and biological evaluation of some novel pyrazolines. Indian J. Pharm. Sci., 69: 470-473.
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