Dr. Faisal Imam

Assistant Professor
King Saud University, Saudi Arabia

Highest Degree
Ph.D. in Clinical Pharmacy from Jamia Hamdard, India

My URL
https://livedna.org/91.32424

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Area of Interest:

Pharmacology and Toxicology
Molecular Biology
Biochemical Studies
Oxidative Stress
Clinical Pharmacy

Selected Publications

  1. Imam, F., N.O. Al-Harbi, M.M. Al-Harbi, W. Qamar and K. Aljerian et al., 2019. Apremilast ameliorates carfilzomib-induced pulmonary inflammation and vascular injuries. Int. immunopharmacol., 66: 260-266.
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  2. Ansari, M.N., R.I. Aloliet, M.A. Ganaie, T.H. Khan, Najeeb-ur-Rehman, F. Imam and A.M. Hamad, 2019. Roflumilast, a phosphodiesterase 4 inhibitor, attenuates cadmium-induced renal toxicity via modulation of NF-κB activation and induction of NQO1 in rats. Hum. Exp. Toxicol., 38: 588-597.
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  3. Ansari, M.N., M.A. Ganaie, N.U. Rehman, K.M. Alharthy and T.H. Khan et al., 2019. Protective role of Roflumilast against cadmium-induced cardiotoxicity through inhibition of oxidative stress and NF-κB signaling in rats. Saudi Pharm. J., 27: 673-681.
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  4. Al-Harbi, N.O., F. Imam, M.M. Al-Harbi, O.A. Al-Shabanah and M.R. Alotaibi et al., 2019. Rutin inhibits carfilzomib-induced oxidative stress and inflammation via the NOS-mediated NF-κB signaling pathway. Inflammopharmacology, 27: 817-827.
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  5. Imam, F., N.O. Al-Harbi, M.M. Al-Harbi, M.A. Ansari and A.F. Al-Asmari et al., 2018. Apremilast prevent doxorubicin-induced apoptosis and inflammation in heart through inhibition of oxidative stress mediated activation of NF-κB signaling pathways. Pharmacol. Rep., 70: 993-1000.
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  6. Alshahrani, S.M., A.S. Alshetaili, A. Alalaiwe, B.B. Alsulays and M.K. Anwer et al., 2018. Anticancer efficacy of self-nanoemulsifying drug delivery system of sunitinib malate. AAPS Pharm. Sci. Tech., 19: 123-133.
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  7. Imam, F., N.O. Al-Harbi, M.M. Al-Harbia, H.M. Korashy and M.A. Ansari et al., 2017. Rutin attenuates carfilzomib-induced cardiotoxicity through inhibition of NF-κB, hypertrophic gene expression and oxidative stress. Cardiovasc. Toxicol., 17: 58-66.
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  8. Alanazi, A., S.G. Algfeley, K.A. Al‐Hosaini, H.M. Korashy and F. Imam et al., 2017. Therapeutic potential of carfilzomib, an irreversible proteasome inhibitor, against acetaminophen‐induced hepatotoxicity in mice. J. Biochem. Mol. Toxicol., Vol. 31. 10.1002/jbt.21877.
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  9. Korashy, H.M., M.A. Ansari, Z.H. Maayah, F. Imam and M. Raish et al., 2016. Differential effects of sunitinib on the expression profiles of xenobiotic-metabolizing enzymes and transporters in rat liver and Kidneys. Basic. Clin. Pharmacol. Toxicol., 119: 73-83.

  10. Iqbal, M., E. Ezzeldin, S.T. Al-Rashood, F. Imam and K.A. Al-Rashood, 2016. Determination of apremilast in rat plasma by UPLC–MS/MS in ESI-negative mode to avoid adduct ions formation. Bioanalysis, 8: 1499-1508.
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  11. Imam, F., N.O. Al-Harbi, M.M. Al-Harbi, M.A. Ansari and M.M. Almutairi et al., 2016. Apremilast reversed carfilzomib-induced cardiotoxicity through inhibition of oxidative stress, NF-κB and MAPK signaling in rats. Toxicol. Mech. Methods, 26: 700-708.
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  12. Bakheet, S.A., A.M. Alhuraishi, N.O. Al‐Harbi, K.A. Al‐Hosaini and S.D. Al‐Sharary et al., 2016. Alleviation of aflatoxin B1‐induced genomic damage by proanthocyanidins via modulation of DNA repair. J. Biochem. Mol. Toxicol., 30: 559-566.
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  13. Khayyam, U.K., S. Muzammil, M. Yunus and F. Imam, 2015. Epidemiological study of obesity in urban population based on body mass index. J. Sci. Pharm., 5: 196-200.

  14. Iqbal, M., N.Y. Khalil, F. Imam, M.K. Anwer, 2015. A validated high-throughput UHPLC-MS/MS assay for accurate determination of rivaroxaban in plasma sample. J. Thromb Thrombolysis, 39: 79-88.
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  15. Imam, F., N.O. Al-Harbi, M.M. Al-Harbi, M.A. Ansari and K.M.A. Zoheir et al., 2015. Diosmin downregulates the expression of T cell receptors, pro-inflammatory cytokines and NF-κB activation against LPS-induced acute lung injury in mice. Pharmacol. Res., 102: 1-11.
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  16. Bhat, M.A., M.A. Al-Omar, M.A. Ansari, K.M.A. Zoheir and F. Imam et al., 2015. Design and synthesis of N-arylphthalimides as inhibitors of glucocorticoid-induced TNF receptor-related protein, proinflammatory mediators, and cytokines in carrageenan-induced lung inflammation. J. Med. Chem. 58: 8850-8867.
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  17. Al-Harbi, N.O., F. Imam, A. Nadeem, M.M. Al-Harbi and H.M. Korashy et al., 2015. Riboflavin attenuates lipopolysaccharide-induced lung injury in rats. Toxicol. Mech. Methods, 25: 417-423.
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  18. Al-Harbi, N.O., A. Nadeem, M.M. Al-Harbi, F. Imam and O.A. Al-Shabanah et al., 2015. Oxidative airway inflammation leads to systemic and vascular oxidative stress in a murine model of allergic asthma. Int. Immunopharmacol., 26: 237-245.
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  19. Nadeem, A., N. Siddiqui, N.O. Alharbi, M.M. Alharbi, F. Imam and M.M. Sayed-Ahmed, 2014. Glutathione modulation during sensitization as well as challenge phase regulates airway reactivity and inflammation in mouse model of allergic asthma. Biochimie., 103: 61-71.
    CrossRef  |  PubMed  |  

  20. Nadeem, A., N. Siddiqui, N.O. Alharbi, M.M. Alharbi and F. Imam, 2014. Acute glutathione depletion leads to enhancement of airway reactivity and inflammation via p38MAPK-iNOS pathway in allergic mice. Int. Immunopharmacol., 22 : 222-229.
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  21. Al-Harbi, N.O., F. Imam, M.M. Al-Harbi, M. Iqbal and A. Nadeem et al., 2014. Olmesartan attenuates tacrolimus-induced biochemical and ultrastructural changes in rat kidney tissue. Biomed. Res. Int., Vol. 2014. 10.1155/2014/607246.
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  22. Al-Harbi, N.O., F. Imam, M.M. Al-Harbi, M. Iqbal and A Nadeem et al., 2014. Treatment with aliskiren ameliorates tacrolimus-induced nephrotoxicity in rats. J. Renin Angiotensin Aldosterone Syst., 16: 1329-1336.
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  23. Al-Harbi, N.O., F. Imam, A. Nadeem, M.M. Al-Harbi and M. Iqbal et al., 2014. Protection against tacrolimus-induced cardiotoxicity in rats by olmesartan and aliskiren. Toxicology Mech. Meth., 24: 697-702.
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  24. Al-Harbi, N.O., F. Imam, A. Nadeem, M.M. Al-Harbi and M. Iqbal et al., 2014. Carbon tetrachloride-induced hepatotoxicity in rat is reversed by treatment with riboflavin. Int. Immunopharmacol., 21: 383-388.
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  25. Saleem, S., M.A. Shaharyar, M.J. Khusroo, P. Ahmad and R.U. Rahman et al., 2013. Anticancer potential of rhamnocitrin 4′-β-d-galactopyranoside against N-diethylnitrosamine-induced hepatocellular carcinoma in rats. Mol. Cell. Biochem., 384: 147-153.
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  26. Kazmi, I., M. Afzal, S. Rahman, M. Iqbal, F. Imam and F. Anwar, 2013. Antiobesity potential of ursolic acid stearoyl glucoside by inhibiting pancreatic lipase. Eur. J. pharmacol., 709: 28-36.
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  27. Afzal, M., I. Kazmi, R. Khan, R. Singh and M. Pravez et al., 2013. Pharmacological evaluation of gatifloxacin in chemically Induced hepatocarcinogenesis: A new tool for hepato-cellularcarcinoma treatment. J. Cancer Sci. Ther., 5: 18-22.
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  28. Munsab, A., S. Manju, A.K. Najmi, I. Faisal, M. Santanu and K.M. Ravinder, 2012. Associated socioeconomic status with illness behavior in tuberculosis patients undergoing DOTS therapy. Indian J. Pharm. Pract., 5: 45-48.
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  29. Ali, M.S., M.S. Alam, F.I. Imam and M.R. Siddiqui, 2012. Topical nanoemulsion of turmeric oil for psoriasis: Characterization, ex vivo and in vivo assessment. Int. J. Drug Delivery, 4: 184-197.
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  30. Alam, M.S., M.S. Ali, N. Alam, M.I. Alam, T. Anwer, F. Imam and M. Shamim, 2012. Design and characterization of nanostructure topical gel of betamethasone dipropionate for psoriasis. J. Applied Pharm. Sci., 2: 148-158.
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  31. Afzal, M., G. Gupta, I. Kazmi, M. Rahman and G. Upadhyay et al., 2012. Evaluation of anxiolytic activity of embelin isolated from Embelia ribes. Biomed. Aging Pathol., 2: 45-47.
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  32. Khayyam, U.K., S. Muzammil and F. Imam, 2011. Distribution of obesity among male and female population based on body mass index and relative body weight. J. Hosp. Clin. Pharmacy., 1: 1-7.

  33. Ansari, M.S., K.U. Khayyam, M. Sharma, F. Imam and D. Behera, 2011. The role of socio-economic factors responsible for non-compliance of directly observed treatment short-course among tuberculosis patients. J. Med. Health Sci., 18: 78-86.
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  34. Khayyam, K.U., F. Imam, M. Sharma, K.K. Pillai and D. Behera, 2010. Pyrazinamide-induced maculopapular rash. Indian J. Dermatol., 55: 384-386.
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  35. Imam, F., M.K. Anwer, M. Iqbal, S. Alam, K.U. Khayyam and M. Sharma, 2010. Tuberculosis: Brief overview and its shifting paradigm for management in India. Int. J. Pharmacol., 6: 755-783.
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  36. Anwer, T., M. Sharma, M. Iqbal, F. Imam and K.K. Pillai, 2009. Comparative analysis of the protective effects of melatonin and silymarin on lipid peroxidation and dyslipidemia in STZ-induced diabetic rats. Hamdard Medicus., 52: 58-61.

  37. Sharma, M., Z.R. Ashraf, K.K. Pillai, D Ahmad and F. Imam, 2008. Protective effect of alpha-ketoglutarate on heart against doxorubicin induced cardiotoxicity in rats. Indian J. Pharmacol., 40: 166-166.

  38. Sharma, M., K.U. Khayyam, V. Kumar, F. Imam, K.K. Pillai and D. Behera, 2008. Influence of honey on adverse reactions due to anti-tuberculosis drugs in pulmonary tuberculosis patients. Continental J. Pharmacol. Toxicol. Res., 2: 6-11.
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  39. Sharma, H., M. Aqil, F. Imam, M.S. Alam, P. Kapur and K.K. Pillai, 2007. A pharmacovigilance study in the department of medicine of a university teaching hospital. Pharmacy Pract., 5: 46-49.
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  40. Aqil, M., F. Imam, A. Hussain, M.S. Alam, P. Kapur and K.K. Pillai, 2006. A pharmacovigilance study for monitoring adverse drug reactions with antihypertensive agents at a South Delhi hospital. Int. J. Pham. Pract., 14: 311-313.
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Member since February, 2020