Dr. Viswanathan Mariammal Berlin Grace

Professor
Department of Biotechnology, Karunya Deemed University, Kidron Quarters, Karunya Nagar, India


Highest Degree
Ph.D. in Biochemistry from University of Madras, India

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Area of Interest:

Biomedical Sciences
Cell Biology
Biotechnology
Immunology
Molecular Biology

Selected Publications

  1. Grace, V.M.B., D.D. Wilson, C. Guruvayoorappan, J.P. Danisha and L. Bonati, 2021. Liposome nano‐formulation with cationic polar lipid DOTAP and cholesterol as a suitable pH‐responsive carrier for molecular therapeutic drug (all‐trans retinoic acid) delivery to lung cancer cells. IET Nanobiotechnol., 15: 380-390.
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  2. Grace, V.B., D.D. Wilson, S. Saranya and R. Peardon, 2021. Regulatory action of all trans retinoic acid on metastasis induced lung cell metabolic changes during implantation of b16f10 cancer cells in c57bl6 mice. J. Pure Appl. Microbiol., 15: 743-751.
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  3. Grace, V.M.B., S. Viswanathan, D.D. Wilson, S.J. Kumar, K. Sahana, E.F.M. Arbin and J. Narayanan, 2020. Significant action of Tridax procumbens L. leaf extract on reducing the TNF-α and COX-2 gene expressions in induced inflammation site in Swiss albino mice. Inflammopharmacology, 28: 929-938.
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  4. Breeta, R.D.I.E., V.M.B. Grace and D.D. Wilson, 2020. Methyl palmitate—a suitable adjuvant for sorafenib therapy to reduce in vivo toxicity and to enhance anti‐cancer effects on hepatocellular carcinoma cells Basic Clin. Pharmacol. Toxicol., 128: 366-378.
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  5. Viswanathan, S., V.M.B. Grace and J.P. Danisha, 2019. Enhancement of tumor suppressor RAR-β protein expression by cationic liposomal-ATRA treatment in benzo(a)pyrene-induced lung cancer mice model Naunyn-Schmiedebergs Arch. Pharmacol., 392: 415-426.
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  6. Ravichandran, R., S. Viswanathan, V.M.B. Grace, L. Bonati and J. Narayanan, 2019. Ameliorating effect of lipo-ATRA treatment on the expression of TIG3 and its suppressing effect on PPARγ gene expression in lung cancer animal model Mol. Cell. Biochem., 460: 105-112.
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  7. Bama, E.S., V.M.B. Grace, V. Sundaram and P.D. Jesubatham, 2019. Synergistic effect of co-treatment with all-trans retinoic acid and 9-cis retinoic acid on human lung cancer cell line at molecular level. 3 Biotech, Vol. 9. 10.1007/s13205-019-1692-x.
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  8. Viswanathan, S. and V.M.B. Grace, 2018. Reduced RAR-β gene expression in Benzo(a)Pyrene induced lung cancer mice is upregulated by DOTAP lipo-ATRA treatment. Gene, 668: 18-26.
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  9. Thangamony, H.H., R. Kumar, C.P. Thangavelu, M. Mariappa, B.G.V. Mariammal and K.N. Brahmadathan, 2018. Nonspecific Amplification of Human DNA by Streptococcus pneumoniae LytA Primer Indian J. Med. Microbiol., 36: 65-69.
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  10. Evangeline, B.R., P.D. Jesubatham, V.M.B. Grace, S. Viswanathan and S. Srividya , 2018. Non-toxic and non teratogenic extract of Thuja orientalis L. inhibited angiogenesis in zebra fish and suppressed the growth of human lung cancer cell line Biomed. Pharmacother., 106: 699-706.
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  11. Suluvoy, J.K. and V.M.B. Grace, 2017. Phytochemical profile and free radical nitric oxide (NO) scavenging activity of Averrhoa bilimbi L. fruit extract 3 Biotech, Vol. 7. 10.1007/s13205-017-0678-9.
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  12. Reji, R.M., B.S.P. SiddikUzzaman and V.M.B. Grace , 2017. Atra entrapped in dspc liposome enhances anti-metastasis effect on lung and liver during b16f10 cell line metastasis in c57bl6 mice. Anti Cancer Agents Med. Chem., 17: 875-884.
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  13. Grace, V.M.B., R.M. Reji and V. Sundaram, 2017. Enhanced expression of tumour suppressor RAR-β by DSPC nano-formulated lipo-ATRA in the lung of B16F10 cell-implanted C57BL6 mice and in A549 cells Life Sci., 184: 10-17.
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  14. Grace, V.M.B. and S. Viswanathan, 2017. Pharmacokinetics and therapeutic efficiency of a novel cationic liposome nano-formulated all trans retinoic acid in lung cancer mice model. J. Drug Delivery Sci. Technol., 39: 223-236.
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  15. Grace, V.M.B., Siddikuzzaman and B. Rimashree, 2015. Liposome encapsulated all trans retinoic acid (atra) has enhanced immunomodulatory and inflammation reducing activities in mice model. Anti Cancer Agents Med. Chem., 15: 196-205.
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  16. Siddikuzzaman and V.M.B. Grace, 2014. Anti-Metastatic Study of Liposome-Encapsulated AlltransRetinoic Acid (ATRA) in B16F10 melanoma cells-implanted C57BL/6 mice. Cancer Invest., 32: 507-517.
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  17. Manjamalai, A., 2013. Chemotherapeutic effect of essential oil of Wedelia chinensis (osbeck) on inducing apoptosis, suppressing angiogenesis and lung metastasis in c57bl/6 mice model. J. Cancer Sci. Ther., 05: 271-281.
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  18. Siddikuzzaman and V.M.B. Grace, 2012. Antioxidant potential of all-transretinoic acid (ATRA) and enhanced activity of liposome encapsulated ATRA against inflammation and tumor-directed angiogenesis. Immunopharmacol. Immunotoxicol., 35: 164-173.
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  19. Siddikuzzaman and G.V.M. Berlin, 2012. Evaluation of immunomodulatory and antitumor activity of alltransretinoic acid (ATRA) in solid tumor bearing mice. Immunopharmacol. Immunotoxicol., 35: 110-118.
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  20. Ramya, D., Siddikuzzaman and V.M.B. Grace, 2012. Effect of all-transretinoic acid (ATRA) on syndecan-1 expression and its chemoprotective effect in benzo(α)pyrene-induced lung cancer mice model. Immunopharmacol. Immunotoxicol., 34: 1020-1027.
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  21. Manjamalai, A., M.J.M. Kumar and V.M.B. Grace, 2012. Essential Oil of Tridax procumbens L Induces Apoptosis and Suppresses Angiogenesis and Lung Metastasis of the B16F-10 Cell Line in C57BL/6 Mice Asian Pac. J. Cancer Prev., 13: 5887-5895.
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  22. Manjamalai, A. and V.M.B. Grace, 2012. The chemotherapeutic effect of essential oil ofPlectranthus amboinicus(lour) on lung metastasis developed by b16f-10 cell line in c57bl/6 mice. Cancer Invest., 31: 74-82.
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  23. Manjamalai, A. and V.M.B. Grace, 2012. Antioxidant activity of essential oils from wedelia chinensis (osbeck) in vitro and in vivo lung cancer bearing c57bl/6 mice. Asian Pac. J. Cancer Prev., 13: 3065-3071.
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  24. Ramya, D., Siddikuzzaman, A. Manjamalai and V.M.B. Grace, 2011. Chemoprotective effect of all-trans retinoic acid (ATRA) on oxidative stress and lung metastasis induced by benzo(a)pyrene. Immunopharmacol. Immunotoxicol., 34: 317-325.
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