Dr. Haleagrahara S. Nagaraja

Senior Lecturer
James Cook University, Australia


Highest Degree
Ph.D. in Medical Science from James Cook University, Australia

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Area of Interest:

Biomedical Sciences
Physiology
Pathology
Pharmacology
Comparative Physiology

Selected Publications

  1. Tudave, D., A. Radhakrishnan, S. Chakravathi and N. Haleagrahara, 2011. Modulation of C-reactive protein and tumour necrosis factor-α in collagen-induces arthritis in dark Agouti rats: Impact of collagen concentration on severity of arthritis. Inflamm. Res., 60: 897-907.
    CrossRef  |  PubMed  |  

  2. Perera, J., J.H. Tan, S. Jeevathayaparan, S. Chakravarthi and N. Haleagrahara, 2011. Neuroprotective effects of alpha lipoic acid on haloperidol-induced oxidative stress in the rat brain. Cell Biosci., 1: 12-12.
    PubMed  |  

  3. Palanisamy, U.D., M. Sivanathan, A.K. Radhakrishnan, N. Haleagrahara, T. Subramaniam and G.S. Chiew, 2011. An effective ostrich oil bleaching technique using peroxide value as an indicator. Molecules, 16: 5709-5719.
    PubMed  |  

  4. Nagaraja, H., C.J. Siew, N.K. Mitra and M. Kumari, 2011. Neuroprotective effect of bioflavonoid quercetin in 6-hydroxydopamine-induced oxidative stress biomarkers in the rat striatum. Neurosci. Lett., 500: 139-143.
    CrossRef  |  

  5. Lisa, M., N. Haleagrahara and S. Chakravarthi, 2011. Insulin-like growth factor-1 (IGF-1) reduces ischemic changes and increaasescirculating angiogenic factors in experimentally-induced myocardial infarction in rats. Vasc. Cell, 3: 13-13.

  6. Jackie, T., H. Nagaraja and C. Srikumar, 2011. Antioxidant effects of Etlingera elatior flower extract against lead acetate - induced perturbations in free radical scavenging enzymes and lipid peroxidation in rats. BMC Res. Notes, 4: 67-67.
    PubMed  |  

  7. Haleagrahara, N., T. Jackie, S. Chakravarthi and A.B. Kulur, 2011. Protective effect of alpha-lipoic acid against lead acetate-induced oxidative stress in the bone marrow of rats. Int. J. Pharmacol., 7: 217-227.

  8. Srikumar, C., H. Nagaraja, 2010. Implementation of PBL curriculum involving multiple disciplines in undergraduate medical education programme. Int. Edu. Stud. Vol. 3 .
    Direct Link  |  

  9. Srikumar, C., H. Nagaraja and J.J. Paul, 2010. Enhancing the Efficacy of Lecturers in Educating Student Cohorts Consisting of Culturally Diverse Groups in a Medical University. Int. Edu. Stud. Vol. 3 .
    Direct Link  |  

  10. Sridhar, B., N. Haleagrahara, R. Bhat, A.B. Kulur, S. Avabratha and P. Adhikary, 2010. Increase in the heart rate variability with deep breathing in diabetic patients after 12-month exercise training. Tohoku J. Exp. Med., 220: 107-113.
    PubMed  |  

  11. Nagaraja, H., T. Jackie, S. Chakaravarthi, M. Rao and T. Pasupathi, 2010. Protective effects of Etlingera elatior extract on lead acetate-induced changes in oxidative biomarkers in bone marrow of rats. Food Chem. Toxicol., 48: 2688-2694.
    CrossRef  |  

  12. Nagaraja, H., T. Jackie, S. Chakaravarthi, A.B. Kulur and M. Rao, 2010. Protective effect of Etlingera elatior (torch ginger) extract on lead acetate-induced hepatotoxicty in rats. J. Toxicol. Sci., 35: 663-671.
    PubMed  |  

  13. Nagaraja, H. and K. Ponnusamy, 2010. Neuroprotective effect of Centella asiaticaextract (CAE) on experimentally induced parkinsonism in aged Sprague-Dawley rats. J. Toxicol. Sci., 35: 41-47.
    PubMed  |  

  14. Choo, Z.W., S. Chakravarthi, W.S. Fung, H.S. Nagaraja and P.M. Thanikachalam et al., 2010. A comparative histopathological study of systemic candidiasis in association with experimentally induced breast cancer. Oncol. Lett., 1: 215-222.

  15. Chakravarthi, S., F.W. Chong, H.S. Nagaraja, N. Lee and P.M. Thani, 2010. c-myc regulation and apoptosis in assessing the beneficial effect of Apigenin in cyclosporine induced nephrotoxicity. Res. J. Pharmacol., 4: 15-20.
    CrossRef  |  

  16. Chakravarthi, S., C.Z. Wei, H.S. Nagaraja, W.S. Fung, M.J. Wah and S. Sreekumar, 2010. A histopathological study of severity of cerebral candidiasis as a result of immunosuppression caused by breast carcinoma. Int. J. Mol. Med. Adv. Sci., 6: 1-7.
    CrossRef  |  Direct Link  |  

  17. Chakravarthi, S., C.Z. Wei, H.S. Nagaraja, W.S. Fung and M.J. Wah et al., 2010. Immunosuppressive effect of disseminated breast carcinoma on severity of hepatic candidiasis. Res. J. Immunol., 3: 1-11.
    CrossRef  |  Direct Link  |  

  18. Chakravarthi, S., C.Z. Wei and H.S. Nagaraja, 2010. Increased susceptibility to opportunistic renal candidiasis due to immunosuppression induced by breast cancer cell lines. Sci. World J., 5: 5-10.

  19. Srikumar C., F.W. Chong and H. Nagaraja, 2009. Apoptosis and expression of bcl-2 in cyclosporine induced renal damage and its reversal by beneficial effects of 4', 5', 7'- trihydroxyflavone. J. Anal. Biosci., 32: 320-327.
    Direct Link  |  

  20. Nayanatara, A.K., H.S. Nagaraja, C. Ramaswamy, K. Bhagyalakshmi, M.R. Bhat and N. Harini, 2009. Estimation of tissue lipid peroxidation level and organ weight in litters of wistar rats exposed to prenatal alcohol ingestion. J. Physiol. Biomed. Sci., 22: 44-47.
    Direct Link  |  

  21. Nayanatara, A., H.S. Nagaraja, C. Ramaswamy, K. Bhagyalakshmi, M.R. Bhat and K.M.D. Gowda, 2009. Venkappa S mantur. Effect of chronic unpredictable stressors on some selected lipid parameters and biochemical parameters in wistar rats. J. Chinese Clin. Med., 4: 92-97.
    Direct Link  |  

  22. Nagaraja, H.S., T.M. Yee, S. Chakravarthi and N. Lee, 2009. Protective effect of N-acetylcysteine on cyclosporine A-induced changes in lipid hydroperoxide levels and renal dysfunction in rats. Arch. Med. Sci., 5: 16-22.

  23. Nagaraja, H.S., R.S. Jassal, S. Chakravarthi, P. Thanikachalam, N. Lee and B.K. Anupama, 2009. Apigenin reduces cyclosporine-A induced changes in lipid hydroperoxides and total antioxidants in Sprague-Dawley rats. J. Chin. Clin. Med., 4: 26-31.
    Direct Link  |  

  24. Nagaraja H., R. Ammu R, L. Nagarajah and K. Ponnusamy. 2009. Flavonoid quercetin protects against swimming stress-induced changes in oxidative biomarkers in hypothalamus of rats. Eur. J. Pharmacol., 621: 46-52.
    CrossRef  |  

  25. Mitra, N.K., H.S. Nagaraja, G. Ponnudurai and J.P. Judson, 2009. The levels of difficulty and discrimination indices in type a multiple choice questions of pre-clinical semester 1 multidisciplinary summative tests. Int. J. Sci, Med. Edu., 3: 2-7.
    Direct Link  |  

  26. Deviprasad, S., M.B. Rameshm, H.S. Nagaraja, A. Prabha and B.K. Anupama, 2009. Coronary artery disease risk factor profile in hypertensive patients. J. Physiol. Biomed. Sci., 21: 68-73.

  27. Chong, F.W., C. Srikumar, H.S. Nagaraja, P.M. Thani and N. Lee, 2009. Expression of transforming growth factor and determination of apoptotic index in histopathological sections for assessment of the effects of Apigenin (4,5,7-Trihydroxyflavone) on Cyclosporine-a induced renal damage. Mal. J. Pathol., 31: 35-43.
    CrossRef  |  PubMed  |  Direct Link  |  

  28. Chakravarthi, S., P. Thanikachalam, H.S. Nagaraja, D.L.W. Yang and N.I. Bukhari, 2009. Assessment of proliferative index and its association with Ki-67 antigen molecule expression in nodular hyperplasia of prostate. Ind. J. Sci. Technol., 2: 1-4.
    Direct Link  |  

  29. Anupama B.K., H. Nagaraja, A. Prabha and P.S. Jeganathan, 2009. Effect of diaphragmatic breathing on heart rate variability in ischemic heart disease with diabetes. Arq. Bras. Cardiol., 92: 423-429.
    Direct Link  |  

  30. Ponnusamy, K., M. Mohan and H.S. Nagaraja, 2008. Protective antioxidant effect of Centella asiatica bioflavonoids on lead acetate induced neurotoxicity. Med. J. Malaysia, 63: 102-102.
    PubMed  |  Direct Link  |  

  31. Niranjan, M., H.S. Nagaraja, B.K. Anupama, N. Bhagyalakshmi, R. Bhat and A. Prabha, 2008. Effect of supervised integrated exercise on deep breathing- heart rate variability in male hypertensive patients. J. Medical Sci., 8: 350-356.
    CrossRef  |  Direct Link  |  

  32. Mitra, N.K. and H.S. Nagaraja, 2008. Effect of chronic ethanol exposure on the count of cerebellar Purkinje cells and motor coordination in adult mice. Eur. J. Anatomy, 12: 67-71.
    Direct Link  |  

  33. Bhagyalakshmi, S., H. Nagaraja, B. Anupama, B. Ramesh, A. Prabha, M. Niranjan and A. Shreedhara, 2007. Effect of supervised integrated exercise on heart rate variability in type 2 diabetes mellitus. Kardiol. Pol., 65: 363-368.
    PubMed  |  

  34. Anupama, B.K., H.S. Nagaraja and P.S. Jeganathan, 2007. Alcohol drinking behaviour in rats exposed to crowding stress. Thai. J. Physiol. Sci., 20: 8-12.

  35. Nagaraja, H.S., B.K. Anupama and P.S. Jeganathan, 2006. Stress responses in albino rats. Thai. J. Physiol. Sci., 19: 8-15.

  36. Nayanatara, A.K., H.S. Nagaraja and B.K. Anupama, 2005. The effect of repeated swimming stress on organ weights and lipid peroxidation in rats. Thai J. Physiol. Sci., 18: 3-9.
    Direct Link  |  

  37. Anupama, N,M., V. Sharma, H.S. Nagaraja and M. Ramesh Bhat, 2005. The serum immunoglobulin E level reflects the severity of bronchial asthma. Thai. J. Physiol. Sci., 18: 35-40.

  38. D'Souza, U.J.A., H.S. Nagaraja, V.M. D'Souza, A. D'Souza and P.S. Jeganathan, 2004. Effect of ethanol on stress induced cardiovascular alterations in rats. Thai. J. Physiol. Sci., 17: 80-85.

  39. Nagaraja, H.S. and P.S. Jeganathan, 2003. Forced swimming stress induced alterations in ingestive behaviors in rats. Indian J. Physiol. Pharmacol., 47: 94-100.

  40. Nagaraja, H.S. and P.S. Jeganathan, 2003. Effect of acute and chronic conditions of overcrowding on free choice ethanol intake in rats. Ind. J. Physiol. Pharmacol., 47: 325-331.
    PubMed  |  

  41. Nagaraja, H.S. and P.S. Jeganathan, 2002. Voluntary alcohol drinking and caloric intake in rats exposed to crowding stress. J. Med. Res., 116: 111-116.
    PubMed  |  

  42. Nagaraja, H.S. and P.S. Jeganathan, 1999. Influence of different types of stress on selected cardiovascular parameters in rats. Ind. J. Physiol. Pharmacol., 43: 296-304.
    PubMed  |  

  43. Nagaraja, H.S. and P.S. Jeganathan, 1999. Forced swimming stress-induced changes in the physiological and biochemical parameters in albino rats. Indian J. Physiol. Pharmacol., 43: 53-59.
    PubMed  |  Direct Link  |  

  44. Nagaraja, H.S. and P.S. Jeganathan, 1999. Effect of short term and long-term restraint stress on some physiological and biochemical parameters in rats. Ind. J. Med. Res., 109: 32-38.

  45. Nagaraja, H.S. and P.S. Jeganathan, 1999. Comparative study of different types of stress on some physiological and biochemical parameters in albino rats. Biomedicine, 19: 137-149.
    Direct Link  |  

  46. Nagaraja, H.S., U.J.A. D'Souza and P.S. Jeganathan, 1997. Effect of isolation and crowding stress on some selected physiological and biochemical parameters in albino rats. Biomedicine, 17: 85-90.