Dr. Rajeev Taliyan

Professor
Birla Institute of Technology and Science, India

Highest Degree
Ph.D. in Pharmacy from Punjab Technical University, India

My URL
https://livedna.org/91.6118

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Area of Interest:

Pharmacology and Toxicology
Pharmacology
Neuropharmacology
Endocrine Pharmacology
Inflammopharmacology

Selected Publications

  1. Wadhwa, G., K.V. Krishna, S.K. Dubey and R. Taliyan, 2023. PEGylated polymer-lipid hybrid nanoparticles to enhance in vivo exposure and uptake of repaglinide in brain cells to treat diabetes-linked neurodegenerative disorders. ACS Appl. Nano Mater., 6: 3497-3512.
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  2. Wadhwa, G., K.V. Krishna, S.K. Dubey and R. Taliyan, 2023. Design and biological evaluation of repaglinide loaded polymeric nanocarriers for diabetes linked neurodegenerative disorder: QbD-driven optimization, in situ, in vitro and in vivo investigation. Int. J. Pharm., Vol. 636. 10.1016/j.ijpharm.2023.122824.
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  3. Sun, J.M., T.L. Yen, J.S. Jan, P.F. Mwale and R.D. Teng et al., 2023. Advances in antibody-based therapeutics for cerebral ischemia. Pharmaceutics, Vol. 15. 10.3390/pharmaceutics15010145.
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  4. Pradhan, R., D. Mishra, S.K. Dubey, R. Khadgawat, G. Kachhawa, T. Gupta and R. Taliyan, 2023. Simultaneous estimation of methyl paraben, propyl paraben, and bisphenol A in the plasma of Indian pregnant women using liquid chromatography-tandem mass spectrometry. Sep. Sci. Plus, Vol. 6. 10.1002/sscp.202200163.
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  5. Kumari, S., R. Taliyan and S.K. Dubey, 2023. Comprehensive review on potential signaling pathways involving the transfer of α-synuclein from the gut to the brain that leads to Parkinson's disease. ACS Chem. Neurosci., 14: 590-602.
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  6. Kakoty, V., K.C. Sarathlal, S. Kumari, Y. Chih-Hao and S.K. Dubey et al., 2023. Brain insulin resistance linked Alzheimer's and Parkinson's disease pathology: An undying implication of epigenetic and autophagy modulation. Inflammopharmacology, 31: 699-716.
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  7. Kakoty, V., K.C. Sarathlal, C.H. Yang, S.K. Dubey and R. Taliyan, 2023. Exploring the epigenetic regulated modulation of fibroblast growth factor 21 involvement in high-fat diet associated Parkinson's disease in rats. ACS Chem. Neurosci., 14: 725-740.
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  8. Gautam, P., K. Ajit, M. Das, R. Taliyan, R. Roy and A. Banerjee, 2023. Age-related changes in gonadotropin-releasing hormone (GnRH) splice variants in mouse brain. J. Exp. Zool. Part A: Ecol. Integr. Physiol., 339: 193-209.
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  9. Wadhwa, G., K.V. Krishna, R. Taliyan, N. Tandon and S.S. Yadav et al., 2022. A novel UPLC–MS/MS method for simultaneous quantification of trigonelline, 4-hydroxyisoleucine, and diosgenin from Trigonella foenum-graecum extract: Application to pharmacokinetic study in healthy and type 2 diabetic rats. Biomed. Chromatogr., Vol. 36. 10.1002/bmc.5275.
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  10. Taliyan, R., V. Kakoty, K.C. Sarathlal, S.S. Kharavtekar and C.R. Karennanavar et al., 2022. Nanocarrier mediated drug delivery as an impeccable therapeutic approach against Alzheimer's disease. J. Controlled Release, 343: 528-550.
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  11. Pradhan. R., M. Pandey, S. Hejmady, R. Taliyan, G. Singhvi, S.K. Dubey and S. Dubey, 2022. Antibody-Drug Conjugates: Development and Applications. In: Targeted Drug Delivery, Bachhav, Y., (Ed.), John Wiley & Sons Hoboken, New Jersey, ISBN: 9783527827855, pp: 425-438.
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  12. Kumar, D., A. Sharma, R. Taliyan, M.T. Urmera and O. Herrera-Calderon et al., 2022. Orchestration of the circadian clock and its association with Alzheimer's disease: Role of endocannabinoid signaling. Ageing Res. Rev., Vol. 73. 10.1016/j.arr.2021.101533.
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  13. Kakoty, V., K.C. Sarathlal, S.K. Dubey, C.H. Yang, S.A. Marathe and R. Taliyan, 2022. Epigenetic regulation and autophagy modulation debilitates insulin resistance associated Alzheimer's disease condition in rats. Metab. Brain Dis., 37: 927-944.
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  14. Kakoty, V., K.C. Sarathlal, M. Pandey, S.K. Dubey, P. Kesharwani and R. Taliyan, 2022. Biological Toxicity of Nanoparticles. In: Nanoparticle Therapeutics Production Technologies, Types of Nanoparticles, and Regulatory Aspects, Kesharwani, P. and K.K. Singh (Eds.), Elsevier, Amsterdam, Netherlands, pp: 603-628.
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  15. Kakoty, V., K.C. Sarathlal, C.H. Yang, S. Kumari, S.K. Dubey and R. Taliyan, 2022. Neuroprotective effect of lentivirus-mediated FGF21 gene delivery in experimental Alzheimer's disease is augmented when concerted with rapamycin. Mol. Neurobiol., 59: 2659-2677.
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  16. Gorantla, S., G. Wadhwa, S. Jain, S. Sankar and K. Nuwal et al., 2022. Recent advances in nanocarriers for nutrient delivery. Drug Delivery Transl. Res., 12: 2359-2384.
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  17. Taliyan, R., V. Kakoty, K.C. S. and S. Kumari, 2021. Fibroblast growth factor 21 and autophagy modulation ameliorates amyloid β-induced Alzheimer disease pathology in rats. Alzheimer Dementia, Vol. 17. 10.1002/alz.058695.
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  18. Nitheesh, Y., R. Pradhan, S. Hejmady, R. Taliyan and G. Singhvi et al., 2021. Surface engineered nanocarriers for the management of breast cancer. Mater. Sci. Eng.: C, Vol. 130. 10.1016/j.msec.2021.112441.
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  19. Pradhan, R., S. Hejmady, R. Taliyan, R. Khadgawat, T. Gupta, G. Kachhawa, R. Kumar, G. Singhvi and S.K. Dubey, 2020. Simultaneous estimation of parabens and bisphenol a in ready-to-eat foodstuffs by using QbD-driven high-pressure liquid chromatography method. Int. J. Environ. Anal. Chem., 102: 2363-2378.
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  20. Ramagiri, S. and R. Taliyan, 2017. Remote limb ischemic post conditioning during early reperfusion alleviates cerebral ischemic reperfusion injury via GSK-3β/CREB/BDNF pathway. Eur. J. Pharmacol., 803: 84-93.
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  21. Ramagiri, S. and R. Taliyan, 2017. Protective effect of remote limb post conditioning via upregulation of heme-oxygenase-1/BDNF pathway in rat model of cerebral ischemic reperfusion injury. Brain Res., 1669: 44-54.
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  22. Ramagiri, S. and R. Taliyan, 2017. Beneficial role of HO-1 upregulation against cerebral ischemic stroke. Cerebrovasc. Dis., 41: 301-301.

  23. Sharma, S. and R. Taliyan, 2016. Histone deacetylase inhibitors: Future therapeutics for insulin resistance and type 2 diabetes. Pharmacol. Res., 113: 320-326.

  24. Sharma, S. and R. Taliyan, 2016. Epigenetic modifications by inhibiting histone deacetylases reverse memory impairment in insulin resistance induced cognitive deficit in mice. Neuropharmacology, 105: 285-297.
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  25. Sharma, S and T. Rajeev, 2016. Epigenetic modifications by inhibiting histone deacetylases reverse memory impairment in insulin resistance induced cognitive deficit in mice. Neuropharmacol., 105: 285-297.
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  26. Mittal, D., R. Taliyan, P.L. Sharma and H.N. Yadav, 2016. Effect of pioglitazone on the abrogated cardioprotective effect of ischemic preconditioning in hyperlipidemic rat heart. Indian J. Pharmacol., 48: 59-63.
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  27. Taliyan, R and R. Shruti, 2015. Delayed neuroprotection against cerebral ischemia reperfusion injury: putative role of BDNF and GSK-3β. J. Recept. Signal Transduction, 36: 402-410.
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  28. Sharma, S., R. Taliyan and S. Singh, 2015. Beneficial effects of sodium butyrate in 6-OHDA induced neurotoxicity and behavioral abnormalities: Modulation of histone deacetylase activity. Behav. Brain Res., 291: 306-314.
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  29. Sharma, S. and R. Taliyan, 2015. Targeting histone deacetylases: A novel approach in parkinson's disease. Parkinson's Dis. Vol. 11. 10.1155/2015/303294.
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  30. Sharma, S and R. Taliyan, 2015. Transcriptional dysregulation in Huntington’s disease: The role of histone deacetylases. Pharmacol. Res., 100: 157-169.
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  31. Sharma, S and R. Taliyan, 2015. Synergistic effects of GSK-3β and HDAC inhibitors in Intracerebroventricular Streptozotocin induced cognitive deficits in rats. J. Naunyn-Schimedberg Arch. Pharmacol., 388: 337-349.
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  32. Ramagiri, S and R. Taliyan, 2015. Neuroprotective effect of hydroxy safflor yellow A against cerebral ischemia-reperfusion injury in rats: Putative role of mPTP. J. Basic Clin. Physiol. Pharmacol., 27: 1-8.
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  33. Sharma, S., R. Taliyan and S. Ramagiri, 2014. Histone deacetylase inhibitor, trichostatin A, improves learning and memory in high-fat diet-induced cognitive deficits in mice. J. Mol. Neurosci., 10.1007/s12031-014-0461-x.
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  34. Sharma, S. and R. Taliyan, 2014. Synergistic effects of GSK-3β and HDAC inhibitors in intracerebroventricular streptozotocin-induced cognitive deficits in rats. Naunyn-Schmiedeberg's Arch. Pharmacol., 10.1007/s00210-014-1081-2.
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  35. Sharma, S. and R. Taliyan, 2014. Neuroprotective role of Indirubin-3'-monoxime, a GSKβ inhibitor in high fat diet induced cognitive impairment in mice. Biochem. Biophys. Res. Commun., 452: 1009-1015.
    CrossRef  |  PubMed  |  

  36. Sharma, S and R. Taliyan, 2014. Histone deacetylase inhibitor, Trichostatin A, improves learning and memory in high fat diet-induced cognitive deficits in mice. J. Mol. Neurosci., 56: 1-11.
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  37. Saini, A.S., R. Taliyan and P.L. Sharma, 2014. Protective effect and mechanism of Ginkgo biloba extract-EGb 761 on STZ-induced diabetic cardiomyopathy in rats. Pharmacognosy Mag., 10: 172-178.
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  38. Taliyan, R. and P.L. Sharma, 2012. Protective effect and potential mechanism of Ginkgo biloba extract EGb 761 on STZ-induced neuropathic pain in rats. Phytother Res., 26: 1823-1829.
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  39. Taliyan, R. and P.L. Sharma, 2012. Possible mechanism of protective effect of thalidomide in STZ-induced-neuropathic pain behavior in rats. Inflammopharmacology, 20: 89-97.
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  40. Singh, G., R. Taliyan and P.L. Sharma, 2012. Pathophysiology of neuropathic pain: A systemic review. Int. J. Pharm. Sci. Res., 3: 3530-3542.

  41. Kumar, A., R. Taliyan and P.L. Sharma, 2012. Evaluation of thyroid hormone induced pharmacological preconditioning on cardiomyocyte protection against ischemic-reperfusion injury. Indian J. Pharmacol., 44: 68-72.
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  42. Chauhan, N., R. Taliyan and P.L. Sharma, 2012. Effect of dipyrone and thalidomide alone and in combination on STZ-induced diabetic neuropathic pain. Naunyn-Schmiedeberg's Arch. Pharmacol., 385: 527-538.
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  43. Taliyan, R., M. Singh, P.L. Sharma, H.N. Yadav and K.S. Sidhu, 2010. Possible involvement of α1-adrenergic receptor and KATP channels in cardioprotective effect of remote aortic preconditioning in isolated rat heart. J. Cardiovasc Dis. Res., 1: 145-151.
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  44. Taliyan, R., M. Singh and P.L. Sharma, 2010. Beneficial effect of cyclosporine in experimental diabetes induced neuropathic pain in rats. Int. J. Pharmacol., 6: 393-399.
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  45. Taliyan, R., M. Singh and P.L Sharma, 2010. Possible mechanism of hyperglycemia induced decrease in antinociceptive effect of analgesics in rats. Int. J. Pharma. Sci. Res., 1: 99-107.

  46. Taliyan, R., M. Singh and P.L Sharma, 2010. Effect of hyperglycemia on antinociceptive effect of cannabinoids-agonist, Win 55,212-2,in STZ induced neuropathic pain in rats. Med. Chem. Res., 19: S103-S104.

  47. Taliyan, R. and P.L. Sharma, 2010. Diabetic neuropathic pain: An update and novel pharmacological strategies for relief of pain. J. Med. Sci., 10: 93-109.
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  48. Arora, A., R. Taliyan and P.L Sharma, 2010. Ameliorative potential of cannabis sativa extract on diabetes induced neuropathic pain. IJPSR, 1: 91-99.
Member since October, 2017