Dr. Lonchin Suguna

Research Scientist
Department of Biochemistry, Central Leather Research Institute, India


Highest Degree
Ph.D. in Biochemistry from University of Madras, Chennai, India

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Area of Interest:

Biochemistry and Molecular Biology
Bioactive Substances
Medicinal Plants
Wound Healing
Antidiabetic Activity

Selected Publications

  1. Selvakumar, G. and S. Lonchin, 2020. Fabrication and characterization of collagen-oxidized pullulan scaffold for biomedical applications. Int. J. Bio. Macromol., 164: 1592-1599.
    CrossRef  |  Direct Link  |  

  2. Kuttalam, I., V. Nagarajan and S. Lonchin, 2020. An ECO-friendly saltless method of preservation of skins using a. marmelos extract. Environ. Sci. Pollut. Res., 27: 23707-23713.
    CrossRef  |  Direct Link  |  

  3. Ponrasu, T., S. Jamuna, A. Mathew, K.N. Madhukumar, M. Ganeshkumar, K. Iyappan and L. Suguna, 2013. Efficacy of L-proline administration on the early responses during cutaneous wound healing in rats. Amino Acids, 45: 179-189.
    CrossRef  |  PubMed  |  Direct Link  |  

  4. Iyappan, K., T. Ponrasu, V. Sangeethapriya, V.S. Gayathri and L. Suguna, 2013. An eco-friendly method for short term preservation of skins/hides using Semecarpus anacardium nut extract. Environ. Sci. Pollut. Res., 20: 6324-6330.
    PubMed  |  

  5. Ganeshkumar, M., T. Ponrasu, M. Sathishkumar and L. Suguna, 2013. Preparation of amphiphilic hollow carbon nanosphere loaded insulin for oral delivery. Colloids Surfaces B: Biointerfaces, 103: 238-243.
    PubMed  |  

  6. Ganeshkumar, M., M. Sathishkumar, T. Ponrasu, M.G. Dinesh and L. Suguna, 2013. Spontaneous ultra fast synthesis of gold nanoparticles using Punica granatum for cancer targeted drug delivery. Colloids Surf. B: Biointerfaces, 106: 208-216.
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  7. Santhosh Kumar, B., M. Ganesh Kumar, L. Suguna, T.P. Sastry and A.B. Mandal, 2012. Pullulan acetate nanoparticles based delivery system for hydrophobic drug. Int. J. Pharma Biosci., 3: 24-32.

  8. Ponrasu, T., M. Ganeshkumar and L. Suguna, 2012. Developmental toxicity evaluation of ethanolic extract of Annona squamosa in zebrafish (Danio rerio) embryo. J. Pharm. Res., 5: 277-279.

  9. Ponrasu, T. and L. Suguna, 2012. Efficacy of a Annona squamosa on wound healing in streptozotocin-induced diabetic rats. Int. Wound J., 9: 613-623.
    PubMed  |  

  10. Iyappan, K., R. Boopathy, L. Suguna, N.G. Ranganathan and N. Vedaraman, 2012. Electro-oxidation of tannery soak water using solar photovoltaic stand-alone systems. J. Acad. Ind. Res., 4: 208-214.

  11. Iyappan, K., L. Suguna, N.K. Chandrababu and N. Vedaraman, 2012. Integration of solar photovoltaic power for wet tanning process application in leather industry. J. Acad. Indus. Res., 1: 118-123.
    Direct Link  |  

  12. Ganeshkumar, M., T.P. Sastry, M. Sathish kumar, M.G. Dinesh , S. Kannappan and L. Suguna, 2012. Sun light mediated synthesis of gold nanoparticles as carrier for 6-mercaptopurine: Characterization and toxicity studies in zebrafish embryo model. Mat. Res. Bull., 7: 2113-2119.
    Direct Link  |  

  13. Ganeshkumar, M., T. Ponrasu, R. Krithika, K. Iyappan, V.S. Subramani Gayathri and L. Suguna, 2012. Topical application of Acalypha indica accelerates rat cutaneous wound healing by up-regulating the expression of type I and III collagen. J. Ethnopharmacol., 142: 14-22.
    PubMed  |  

  14. Bhuvaneswari, B., R. Hari, R. Vasuki and L. Suguna, 2012. Antioxidant and antihepatotoxic activities of ethanolic extract of Solanum torvum. Asian J. Pharm. Clin. Res., 5: 147-150.
    Direct Link  |  

  15. Arulprakash, K., R. Murugan, T. Ponrasu, K. Iyappan, V.S. Gayathri and L. Suguna, 2012. Efficacy of Ageratum conyzoides on tissue repair and collagen formation in rats. Clin. Exp. Dermatol., 37: 418-424.
    CrossRef  |  PubMed  |  Direct Link  |  

  16. Rajesh, K., R.J. Verma, P. Srivatsav and L. Suguna, 2011. Phyllanthin of standardised P. amarus extract attenuates liver oxidative stress in mice and exerts cytoprotective activity on human hepatoma cell line. J. Clin. Exp. Hepatol., 1: 57-67.

  17. Sumitra, M., P. Manikantan, V.S. Gayathri, P. Mahendran and L. Suguna, 2009. Emblica officinalis exerts wound healing action through upregulation of collagen and extracellular signal-regulated kinases (Erk1/2). Wound Repair Regenerat., 17: 99-107.
    PubMed  |  

  18. Suguna, L., V. Rathinasamy, K. Iyappan, N.K. Chandrababu and A.B. Mandal, 2009. Alternatives to salt preservation: Preservation by reducing moisture content. Asian J. Water Environ. Poll., 6: 119-122.

  19. Suguna, L., K. Iyappan, V. Rathinasamy, N.K. Chandrababu and A.B. Mandal, 2009. An eco-friendly method for short term preservation of skins/hides. Indian Leather, 43: 35-42.

  20. Suguna, L., V. Rathinasamy, K. Iyappan, N.K. Chandrababu and A.B. Mandal, 2008. An eco-friendly method for short term preservation of skins using extract from Aegle marmelos. Indian Leather, 41: 115-125.

  21. George, J., L. Suguna, R. Jayalakshmi and G. Chandrakasan, 2007. Efficacy of silymarin and curcumin on dimethylnitrosamine induced liver fibrosis in rats. Biomedicine, 26: 18-26.

  22. Manikandan, P., M. Sumitra, V.S. Gayathri and L. Suguna, 2006. Curcumin modulates collagen characteristics and free radical quenching during wound healing in rats. Mol. Cell. Biochem., 290: 87-96.

  23. Sumitra, M., P. Manikandan and L. Suguna, 2005. Efficacy of Butea monosperma on dermal wound healing in rats. Int. J. Biochem. Cell Biol., 37: 566-573.
    CrossRef  |  PubMed  |  

  24. Ratnam, G., L. Suguna, K. Hari Prasad and G. Chandrakasan, 2005. Establishment of an in vitro model for hepatic fibrosis: Isolation and characterization of hepatic stellate cells. Biomedicine, 25: 64-71.

  25. Venkateswaran, S., L. Pari, L. Suguna and G. Chandrakasan, 2003. Modulatory effect of Coccinia indica on aortic collagen in streptozotocin-induced diabetic rats. Clin. Exp. Pharmacol. Physiol., 30: 157-163.

  26. Sivakumar, P., L. Suguna and G.Chandrakasan, 2003. Similarity between the major collagens of cuttlefish cranial cartilage and cornea. Comparat. Biochem. Physiol., 134: 171-180.

  27. Sathian, , T.P. Sastry, L. Suguna, Y.L. Narayana and G.R. Krishnan, 2003. Fibrin as a matrix for grafting 2-hydroxyethyl methacrylate: preparation and characterization of the graft and its in vivo evaluation for wound healing. J. Biomed. Mat. Res., 64: 435-440.

  28. Nithya, M., L. Suguna and C. Rose, 2003. The effect of Nerve Growth Factor (NFG) on the early responses during the process of wound healing. Biochim. Biophys. Acta, 1620: 25-31.

  29. Suguna, L., S. Singh, P. Sivakumar, P. Sampath and G. Chandrakasan, 2002. Influence of Terminalia chebula on dermal wound healing in rats. Phytother. Res., 16: 223-227.
    Direct Link  |  

  30. Sumitra, M., P. Manikandan, L. Suguna and G Cehittar, 2000. Study of dermal wound healing activity of Trigonella foenum graceum in rats. J. Clin. Biochem. Nutr., 28: 59-67.

  31. Sivakumar, P., R. Arichandran, L. Suguna, M. Mariappan and G. Chandrakasan, 2000. Impact of tannery effluent on collagen and molecular modifications in fresh water fish. J. Fish Biol., 56: 1012-2000.

  32. Sivakumar, P., L. Suguna and G. Chandrakasan, 2000. Biochemical and physicochemical characterization of the heterotrimeric type V/XI like collagen from squid cranial cartilage and its similarity to the squid corneal collagen. Comparat. Biochem. Physiol., 125: 555-562.