Dr. Toche Raghunath Baban

Research Scientist
Organic Chemistry Research Centre, India


Highest Degree
Ph.D. in Synthetic Organic Chemistry from University of Pune, Pune, India

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Area of Interest:

Chemistry
Synthetic Organic Chemistry
Organic Chemistry
Chromatography
Green Chemistry

Selected Publications

  1. Toche, R.B., R.A. Janrao, S.A. Gangurde and P. S. Nikam, 2013. Sulfamic acid mediated efficient one-pot synthesis of novel 5-substituted 1,3,4-thiadiazol-2-ylcarbamoyl) aliphatic amide acid derivatives. Synthetic Commun.: Int. J. Rapid Commun. Synthetic Organic Chem., 43: 2527-2535.
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  2. Toche, R.B. and S.N. Chavan, 2013. Synthesis and study the effect of donor-acceptor substituent on fluorescence behavior of thieno [3, 2-c]pyridine derivatives. J. Fluoresc., (In Press). 10.1007/s10895-013-1313-8.
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  3. Toche, R.B. and R. Janrao, 2013. An efficient microwave-assisted Suzulki cross-coupling reactions on quinoline derivatives in water and study the electronic effect thereof. Int. J. Sci. Res., 3: 1-9.
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  4. Patil, S.P., S.B. Kanawade, D.C. Bhavsar, P.S. Nikam, S.A. Gangurde and R.B. Toche, 2013. Syntheses of new unsymmetrical 2,5-disubstituted-1,3,4-oxadiazoles and 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles bearing thieno[2,3-c]pyrazolo moiety. J. Heteroc. Chem., (In Press). 10.1002/jhet.1584.
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  5. Kanawade, S.B., R.B. Toche and D.P. Rajani, 2013. Synthetic tactics of new class of 4-aminothieno[2,3-d]pyrimidine-6-carbonitrile derivatives acting as antimicrobial agents. Eur. J. Medic. Chem., 64: 314-320.
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  6. Gangurde, S.A., S.B. Kanawade, P.S. Nikam, D.C. Bhavsar and R.B. Toche, 2013. New synthesis and reactions of ethyl 5-amino-4-cyano-1-phenyl-1H-pyrazole-3-carboxylate. J. Heteroc. Chem., (In Press). 10.1002/jhet.1691.
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  7. Bhavsar, D.C., P.S. Nikam, S.A. Gangurde and R.B. Toche, 2013. Synthesis of polysubstituted pyrazolo[3,4-b]pyridine-3-carbohydrazide and pyrazolo[3,4-d]pyridazine derivatives. J. of Heteroc. Chem., (In Press). 10.1002/jhet.1779.
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  8. More, B.P., M.K. Malve, R.B. Toche and D.B. Shinde, 2012. Analysis of adulterant kerosene in diesel by kinematic viscosity measurement. Int. J. Pharm. Biol. Sci., 2: 256-261.
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  9. Kanawade, S.B., S.P. Patil, P.S. Nikam, S.A. Gangurde, M.N. Jachak and R.B. Toche, 2012. Synthesis of new thieno[2,3-d]pyrimidines, thieno[3,2-e]pyridines, and thieno[2,3-d][1,3]oxazines. J. Heteroc. Chem., 49: 363-369.
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  10. Toche, R.B., R.A. Janrao, S.M. Bagul, S.P. Patil, B.P. Pagar and P.S. Nikam, 2011. Arylbenzo[h][1, 6]naphthyridine derivatives: Synthesis and photophysical properties. J. Fluoresc., 21: 1617-1624.
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  11. Toche, R.B., M.A. Kazi, P.S. Nikam and D.C. Bhavsar, 2011. Synthesis of nicotinonitrile derivatives and study of their photophysical properties. Monatshefte fur Chemie-Chemical Monthly, 142: 261-269.
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  12. Shelar, D.P., S.R. Patil, R.V. Rote, R.B. Toche and M.N. Jachak, 2011. Synthesis and fluorescence investigation of differently substituted benzo[b][1,8]naphthyridines: Interaction with different solvents and Bovine Serum Albumin (BSA). J. Fluoresc., 21: 1033-1047.
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  13. Shelar, D.P., D.R. Birari, R.V. Rote, S.R. Patil, R.B. Tocheand M.N. Jachak, 2011. Novel synthesis of 2-aminoquinoline-3-carbaldehyde, benzo[b][1,8]naphthyridines and study of their fluorescence behavior. J. Phys. Org. Chem., 24: 203-211.
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  14. Rote, R.V., D.P. Shelar, S.R. Patil, S.S. Shinde, R.B. Toche and M.N. Jachak, 2011. Effect of donor-acceptor chromophores on photophysical properties of newly synthesized Pyrazolo-Pyrrolo-Pyrimidines (PPP). J. Fluoresc., 21: 453-459.
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  15. Patil, S.R., D.P. Shelar, R.V. Rote, R.B. Toche and M.N. Jachak, 2011. Effect of specific solute-solvent interaction and electron donor-acceptor substituents of novel pyrazolo naphthyridines on fluorescence. J. Fluoresc., 21: 461-471.
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  16. Patil, S.P., D.P. Shelar and R.B. Toche, 2011. Synthesis of pyrazolopyridine annulated heterocycles and study the effect of substituents on photophysical properties. J. Fluoresc., 22: 31-41.
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  17. Mane, D.V., K.V kulkarni, D.B. Shinde, R.B. Toche and M.V. Garad, 2011. A new chromogenic spray reagent for detection and identification of hydrogen Cyanamid. Global J. Anal. Chem., 2: 46-49.

  18. Kanawade, S.B., R.B. Toche, S.P. Patil, A.E. Desai and S.S. Bhamare, 2011. Aminothiophenedicarboxamides and dicyanothiopheneacetamides as effective synthetic molluscicides against Indoplanorbis exustus snail. Eur. J. Med. Chem., 46: 4682-4686.
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  19. Jachak, M.N., S.M. Bagul, M.A. Kazi and R.B. Toche, 2011. Novel synthetic protocol toward pyrazolo[3,4-h]-[1,6]naphthyridines via Friedlander condensation of new 4-aminopyrazolo[3,4-b]pyridine-5-carbaldehyde with reactive α-methylene ketones. J. Heteroc. Chem., 48: 295-300.
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  20. Gaikwada, V.B., S.M. Bakreb, R.B. Tochea and S.S. Gaikwada, 2011. Degradation profile of vegetable oil by bacteria in soil matrix using GC-MS. Global J. Anal. Chem., 2: 33-45.
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  21. Toche, R.B., M.A. Kazi, S.P. Patil, S.B. Kanawade and M.N. Jachak, 2010. Synthesis of quinolone substituted pyrazoles, isoxazoles and pyridines as a potential blue luminophors. J. Fluoresc., 20: 1129-1137.
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  22. Toche, R.B., D.C. Bhavsar, M.A. Kazi, S.M. Bagul and M.N. Jachak, 2010. Synthesis of pyrazolopyridine 3-carboxylates by Friedlander condensation. J. Heteroc. Chem., 47: 287-291.
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  23. Toche, R.B., B.P. Pagar, R.R. Zoman, G.B. Shinde and M.N. Jachak, 2010. Synthesis of novel benzo[h][1,6]naphthyridine derivatives from 4-aminoquinoline and cyclic β-ketoester. Tetrahedron, 66: 5204-5211.
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  24. Rane, B.S., M.A. Kazi, S.M. Bagul, D.P. Shelar, R.B. Toche and M.N. Jachak, 2010. Synthesis of novel spiro-oxazino-quinoline derivatives and study of their photophysical properties. J. Fluoresc., 20: 415-420.
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  25. Kulkarni, K.V., D.B. Shinde, D.V. Mane, R.B. Toche and M.V. Garad, 2010. New chromogenic spray reagent for detection and identification of carbonsulfan. J. Planar Chromatogar., 23: 373-375.
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  26. Jachak, M.N., S.M. Bagul, D.R. Birari, M.G. Ghagare, M.A. Kazi, R.B. Toche and V.T. Mathad, 2010. Synthesis and fluorescence properties of donor-acceptor-substituted novel dipyrazolo[3,4-b:3',4'-d]pyridines (DPP). J. Fluoresc., 20: 787-796.
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  27. Jachak, M.N., D.R. Birari, R.B. Toche, M.G. Ghagare and S.M. Bagul, 2010. Synthesis of uracil derivatives and their alkylation: An approach to peptide non-nucleic acid monomers. Monatshefte fur Chemie-Chemical Monthly, 141: 451-459.
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  28. Ghotekar, B.K., M.G. Ghagare, R.B. Toche and M.N. Jachak, 2010. Synthesis of new quinoline fused heterocycles such as benzo[h]-1,6-naphthyridines and pyrazolo[4,3-c]quinolines. Monatshefte fur Chemie-Chemical Monthly, 141: 169-175.
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  29. Ghagare, M.G., D.R. Birari, D.P. Shelar, R.B. Toche and M.N. Jachak, 2010. Novel and efficient synthesis of pyrimidine derivatives. Synthetic Commun.: Int. J. Rapid Commun. Synth. Organic Chem., 40: 1580-1587.
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  30. Tochea, R.B., M.A. Kazia and M.N. Jachaka, 2009. Synthesis of 4-cyano- and 5-aminopyrazoles and deamination of 5-aminopyrazoles. Organic Prepara. Proced. Int.: New J. Organic Synth., 40: 551-556.
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  31. Toche, R.B., M.A. Kazi, M.N. Jachak and A.E. Desai, 2009. Synthesis and molluscicidal activities of quinolone substituted pyrazoline and isoxazoline derivatives. J. Applied Sci. Res., 6: 637-641.

  32. Toche, R.B., M.A. Kazi, B.K. Ghotekar, S.M. Bagul, C.D. Tantak and M.N. Jachak, 2009. Fluorescence properties of donor acceptor chromophores on newly synthesized pyridine-3-carbonitriles. J. Fluoresc., 19: 1119-1124.
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  33. Biraria, D.R., M.G. Ghagarea, M.A. Kazia, S.M. Bagula, B.K. Ghotekara, R.B. Tochea and M.N. Jachaka, 2009. Synthesis of cytosine derivatives and study of their alkylation under mild conditions. Organic Prepara. Proced. Int.: New J. Organic Synth., 41: 515-532.
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  34. Toche, R.B., B.K. Ghotekar, D.B. Kendre, M.A. Kazi and M.N. Jachak, 2008. An efficient synthesis of pyrazolo[3,4-b]pyrrolo[2,3-d]pyridines from 5-aminopyrazoles and cyclic β-keto ester. J. Heteroc. Chem., 45: 1711-1717.
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  35. Kendre, D.B., R.B. Toche and M.N. Jachak, 2008. Michael addition of dimedone with α,β-unsaturated ketones: Synthesis of quinoline and chromene derivatives. J. Heteroc. Chem., 45: 667-671.
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  36. Jachak, M.N., A.B. Avhale, B.K. Ghotekar, D.B. Kendre and R.B. Toche, 2008. Synthesis of pyrazolo[3,4-b]pyridines using ammonium acetate as green reagent in multi-component reactions. J. Heteroc. Chem., 45: 1221-1224.
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  37. Ghotekar, B.K., M.A. Kazi, M.N. Jachak and R.B. Toche, 2008. Effect of substituents on absorption and fluorescence properties of pyrazolo[3,4-b]pyrrolo[2,3-d]pyridines. Can. J. Chem., 86: 1070-1076.
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  38. Toche, R.B., B.K. Ghotekar, M.A. Kazi, D.B. Kendre and M.N. Jachak, 2007. Synthesis of fused pyrimidines from amines and cyclic β-formylesters. Tetrahedron, 63: 8157-8163.
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  39. Kendre, D.B., R.B. Toche and M.N. Jachak, 2007. Synthesis of novel dipyrazolo[3,4-b:3,4-d]pyridines and study of their fluorescence behavior. Tetrahedron, 63: 11000-11004.
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  40. Jachak, M.N., D.B. Kendre, A.B. Avhale, R.B. Toche and R.W. Sabnis, 2007. A novel synthesis of benzo[h]quinolines and study of their fluorescence properties. J. Heteroc. Chem., 44: 1525-1528.
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  41. Jachak, M.N., A.B. Avhale, R.B. Toche and R.W. Sabnis, 2007. Synthesis of pyrazolo-annelated heterocyclic ring compounds such as pyrazolo[3,4-b]pyridines and pyrazolo[4′,3′:5,6]-pyrido[2,3-d]pyrimidines. J. Heteroc. Chem., 44: 343-347.
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  42. Jachak, M.N., A.B. Avhale, V.J. Medhane and R.B. Toche, 2006. A convenient route for the synthesis of pyrazolo[3,4-d]pyrimidine, pyrazolo[3,4-b][1,6]naphthyridine and pyrazolo[3,4-b]quinoline derivatives. J. Heteroc. Chem., 43: 1169-1175.
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  43. Tochea, R.B., M.N. Jachaka, N.S. Badgujara, A.B. Avhalea and D.B. Kendrea, 2005. Formation of oxiranes during the preparation of aroylacetonitriles. Organic Prepara. Proced. Int.: New J. Organic Synth., 37: 405-408.
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  44. Jachak, M.N., A.B. Avhale, C.D. Tantak, R.B. Toche, C. Reidlinger and W. Stadlbauer, 2005. Friedlander condensation of 5-aminopyrazole-4-carbaldehydes with reactive α-methylene ketones: Synthesis of pyrazolo[3,4-b]pyridines. J. Heteroc. Chem., 42: 1311-1319.
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  45. Jachak, M.N., C.D. Tantak, R.B. Toche and N.S. Badgujar, 2004. A convenient route for the synthesis of 4-aryl- and 4-aminopyrimidines. Monatshefte fur Chemie/Chemical Monthly, 135: 1529-1538.
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