Dr. Aamir Ahmad

Research Scientist
Wayne State University, USA

Highest Degree
Ph.D. in Biochemistry from Aligarh Muslim University, Aligarh, India

My URL
https://livedna.org/91.701

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Area of Interest:

Biomedical Sciences
Breast Cancer
Cancer Stem Cells
Chemoprevention
Metastasis

Selected Publications

  1. Wang, Z., Y. Li, A. Ahmad, S. Banerjee and A.S. Azmi et al., 2011. Down-regulation of Notch-1 is associated with Akt and FoxM1 in inducing cell growth inhibition and apoptosis in prostate cancer cells. J. Cell. Biochem., 112: 78-88.
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  2. Ahmad, A., Z. Wang, D. Kong, R. Ali and S. Ali et al., 2011. Platelet-derived growth factor-D contributes to aggressiveness of breast cancer cells by up-regulating Notch and NF-κB signaling pathways. Breast Cancer Res. Treat., 126: 15-25.
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  3. Wang, Z., Y. Li, D. Kong, A. Ahmad, S. Banerjee and F.H. Sarkar, 2010. Cross-talk between miRNA and Notch signaling pathways in tumor development and progression. Cancer Lett., 292: 141-148.
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  4. Wang, Z., Y. Li, A. Ahmad, A.S. Azmi and S. Banerjee et al., 2010. Targeting Notch signaling pathway to overcome drug resistance for cancer therapy. Biochim. Biophys. Acta, Rev. Cancer, 1806: 258-267.
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  5. Wang, Z., A. Ahmad, Y. Li, S. Banerjee, D. Kong and F.H. Sarkar, 2010. Forkhead box M1 transcription factor: A novel target for cancer therapy. Cancer Treatment Rev., 36: 151-156.
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  6. Wang, Z., A. Ahmad, Y. Li, D. Kong, A.S. Azmi, S. Banerjee and F.H. Sarkar, 2010. Emerging roles of PDGF-D signaling pathway in tumor development and progression. Biochimica Biophys. Acta (BBA) Rev. Cancer, 1806: 122-130.
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  7. Wang, Z., A. Ahmad, S. Banerjee, A. Azmi, D. Kong, Y. Li and F.H. Sarkar, 2010. FoxM1 is a novel target of a natural agent in pancreatic cancer. Pharmaceutical Res., 27: 1159-1168.
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  8. Padhye, S., A. Ahmad, N. Oswal, P. Dandawate, R.A. Rub, J. Deshpande, K.V. Swamy and F.H. Sarkar, 2010. Fluorinated 2`-hydroxychalcones as garcinol analogs with enhanced antioxidant and anticancer activities. Bioorg. Med. Chem. Lett., 20: 5818-5821.
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  9. Hadi, S.M., M.F. Ullah, A.S. Azmi, A. Ahmad, U. Shamim, H. Zubair and H.Y. Khan, 2010. Resveratrol mobilizes endogenous copper in human peripheral lymphocytes leading to oxidative DNA breakage: a putative mechanism for chemoprevention of cancer. Pharmaceutical Res., 27: 979-988.
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  10. Ali, S., A. Ahmad, S. Banerjee, S. Padhye and K. Dominiak et al., 2010. Gemcitabine sensitivity can be induced in pancreatic cancer cells through modulation of miR-200 and miR-21 expression by curcumin or its analogue CDF. Cancer Res., 70: 3606-3617.
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  11. Ahmad, A., Z. Wang, D. Kong, S. Ali and Y. Li et al., 2010. FoxM1 down-regulation leads to inhibition of proliferation, migration and invasion of breast cancer cells through the modulation of extra-cellular matrix degrading factors. Breast Cancer Res. Treatment, 122: 337-346.
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  12. Ahmad, A., W.A. Sakr and K.M.W. Rahman, 2010. Anticancer properties of indole compounds: mechanism of apoptosis induction and role in chemotherapy. Current Drug Targets, 11: 652-666.
    CrossRef  |  PubMed  |  

  13. Wang, Z., Y. Li, D. Kong, S. Banerjee and A. Ahmad et al., 2009. Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of notch signaling pathway. Cancer Res., 69: 2400-2407.
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  14. Wang, Z., A. Azmi, A. Ahmad, S. Banerjee, S. Wang, F. Sarkar and R. Mohammad, 2009. TW-37, a small-molecule inhibitor of Bcl-2, inhibits cell growth and induces apoptosis in pancreatic cancer: Involvement of Notch-1 signaling pathway. Cancer Res., 69: 2757-2765.
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  15. Rahman, K.M.W., S. Banerjee, S. Ali, A. Ahmad, Z. Wang, D. Kong and W.A. Sakr, 2009. 3, 3`-Diindolylmethane enhances taxotere-induced apoptosis in hormone-refractory prostate cancer cells through survivin down-regulation. Cancer Res., 69: 4468-4475.
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  16. Padhye, S., A. Ahmad, N. Oswal and F.H. Sarkar, 2009. Emerging role of garcinol, the antioxidant chalcone from Garcinia indica choisy and its synthetic analogs. J. Hematol. Oncol., 2: 1-13.
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  17. Nazeem, S., A.S. Azmi, S. Hanif, A. Ahmad, R.M. Mohammad, S.M. Hadi and K. S. Kumar, 2009. Plumbagin induces cell death through a copper-redox cycle mechanism in human cancer cells. Mutagenesis, 24: 413-418.
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  18. Kong, D., Y. Li, Z. Wang, S. Banerjee, A. Ahmad, H.R. Choi Kim and F.H. Sarkar, 2009. MiR-200 regulates PDGF-D-mediated epithelial-mesenchymal transition, adhesion, and invasion of prostate cancer cells. Stem Cells, 27: 1712-1721.
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  19. Ahmad, A., S. Banerjee, Z. Wang, D. Kong, A.P.N. Majumdar and F.H. Sarkar, 2009. Aging and inflammation: Etiological culprits of cancer. Current Aging Sci., 2: 174-186.
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  20. Ahmad, A., D. Kong, Z. Wang, S.H. Sarkar, S. Banerjee and F.H. Sarkar, 2009. Down-regulation of uPA and uPAR by 3, 3`-Diindolylmethane contributes to the inhibition of cell growth and migration of breast cancer cells. J. Cell. Biochem., 108: 916-925.
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  21. Ahmad, A., D. Kong, S.H. Sarkar, Z. Wang, S. Banerjee and F.H. Sarkar, 2009. Inactivation of uPA and its receptor uPAR by 3, 3`-Diindolylmethane (DIM) leads to the inhibition of prostate cancer cell growth and migration. J. Cell. Biochem., 107: 516-527.
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  22. Padhye, S., S. Banerjee, A. Ahmad, R. Mohammad and F.H. Sarkar, 2008. From here to eternity-the secret of pharaohs: Therapeutic potential of black cumin seeds and beyond. Cancer Ther., 6: 495-510.
    PubMed  |  Direct Link  |  

  23. Khundmir, S.J., A. Ahmad, R. Bennett, E. Weinman and D. Steplock et al., 2008. Novel regulatory function for NHERF-1 in Npt2a transcription. Am. J. Physiol. Renal Physiol., 294: F840-F849.
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  24. Dass, K., A. Ahmad, A.S. Azmi, S.H. Sarkar and F.H. Sarkar, 2008. Evolving role of uPA/uPAR system in human cancers. Cancer Treatment Rev., 34: 122-136.
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  25. Azmi, A.S., A. Ahmad, S. Banerjee, V.M. Rangnekar, R.M. Mohammad and F.H. Sarkar, 2008. Chemoprevention of pancreatic cancer: Characterization of par-4 and its modulation by 3,3` Diindolylmethane (DIM). Pharmaceutical Res., 25: 2117-2124.
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  26. Ali, S., S. Banerjee, A. Ahmad, B.F. El-Rayes, P.A. Philip and F.H. Sarkar, 2008. Apoptosis-inducing effect of erlotinib is potentiated by 3, 3'-diindolylmethane in vitro and in vivo using an orthotopic model of pancreatic cancer. Mol. Cancer Ther., 7: 1708-1719.
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  27. Khundmiri, S.J., E.J. Weinman, D. Steplock, J. Cole and A. Ahmad et al., 2005. Parathyroid hormone regulation of Na+,K+-ATPase requires the PDZ 1 domain of sodium hydrogen exchanger regulatory factor-1 in opossum kidney cells. J. Am. Society Nephrol., 16: 2598-2607.
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  28. Ahmad, A., S.F. Asad, S. Singh and S.M. Hadi, 2005. Prooxidant activity of resveratrol in the presence of copper ions: Mutagenicity in plasmid DNA. Toxicol. Lett., 159: 1-12.
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Member since June, 2010