Dr. Packirisamy Gopinath

Assistant Professor
Indian Institute of Technology, India

Highest Degree
Ph.D. in Biotechnology from Indian Institute of Technology, India

My URL
https://livedna.org/91.8192

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Biography

Dr. Packirisamy Gopinath is currently working as Assistant Professor at Indian Institute of Technology, India. He obtained his PhD in Biotechnology from same Institute. He also appointed as Assistant Professor at Amrita University, Post Doctoral Research Associate at University of Rochester Medical Center, Rochester, New York, USA, and Senior Research Fellow at Indian Institute of Technology, India. His main area of research interest related to Cancer Nanotheranostics, Stem Cell Therapy, Tissue Engineering, and Nano-Remediation. Dr. Packirisamy Gopinath received honor includes Received Bharat Jyoti Award from Dr. Bhishma Narain Singh (Former Governor of Tamil Nadu and Assam) at a seminar, University rank holder in M.Sc., Biotechnology, his research articles published in Biomaterials Science (2015) and Journal of Materials Chemistry B (2015) have been selected for cover page of the issue, and many others. He has published 23 research articles in journals, 5 books, 3 book chapters, and more than 27 abstract/presentations in conferences contributed as author/co-author. He is life member of Indian Nanoscience Society, Society for Biomaterials and Artificial Organs, Society for Tissue Engineering and Regenerative Medicine, Indian Science Congress Association, and Indian society of chemists and Biologists. He successfully completed 5 M.Tech project. Currently he is supervising 8 PhD, 1 M.Tech, 2 MSc and 2 B.Tech students. He also conducted 4 workshops/short term courses.

Area of Interest:

Molecular Sciences
Cancer Nanotheranostics
Stem Cell Therapy
Tissue Engineering
Nano-Remediation

Selected Publications

  1. Sachdev, A., I. Matai and P. Gopinath, 2015. Dual-functional carbon dots-silver@ zinc oxide nanocomposite: In vitro evaluation of cellular uptake and induction of apoptosis. J. Mater. Chem. B, 3: 1208-1220.
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  2. Matai, I., A. Sachdev and P. Gopinath, 2015. Multicomponent 5-fluorouracil loaded PAMAM stabilized-silver nanocomposites synergistically induce apoptosis in human cancer cells. Biomater. Sci., 3: 457-468.
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  3. Malwal, D. and P. Gopinath, 2015. Fabrication and characterization of poly (ethylene oxide) templated nickel oxide nanofibers for dye degradation. Environ. Sci.: Nano, 2: 78-85.
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  4. Gopinath, P., S.U. Kumar, I. Matai, B. Bhushan, D. Malwal, A. Sachdev and P. Dubey, 2015. Cancer Nanotheranostics. Springer, New York, ISBN: 978-981-287-434-4, Pages: 119.

  5. Bhushan, B., P. Dubey, S.U. Kumar, A. Sachdev, I. Matai and P. Gopinath, 2015. Bionanotherapeutics: Niclosamide encapsulated albumin nanoparticles as a novel drug delivery system for cancer therapy. RSC Adv., 5: 12078-12086.
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  6. Sachdev, A., I. Matai and P. Gopinath, 2014. Implications of surface passivation on physicochemical and bioimaging properties of carbon dots. RSC Adv., 4: 20915-20921.
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  7. Sachdev, A. and P. Gopinath, 2014. Chitosan based Carbon Nanodots and Nanoparticles for Bio-Applications. Lambert Academic Publishing, Germany, ISBN: 978-3-659-30120-9, Pages: 72.

  8. Matai, I., A. Sachdev, S.U. Kumar, P. Dubey, B. Bhushan and P. Gopinath, 2014. Dendrimer: A Promising Nanocarrier for Cancer Therapy. In: Nanotechnology: Recent Trends, Emerging Issues and Future Directions, Islam, N. (Ed.). Chapter 7, Nova Science Publishers, New York, ISBN 978-1-63117-561-9, pp: 127-155.

  9. Matai, I., A. Sachdev, P. Dubey, S.U. Kumar, B. Bhushan and P. Gopinath, 2014. Antibacterial activity and mechanism of Ag-ZnO nanocomposite on S. Aureus and GFP-expressing antibiotic resistant E. Coli. Colloids Surf. B: Biointerfaces, 115: 359-367.
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  10. Matai, I. and P. Gopinath, 2014. Novel Nanocomposites and Nanofibers for Biomedical Applications. Lambert Academic Publishing, Germany, ISBN: 978-3-659-31255-7, Pages: 68.

  11. Malwal, D. and P. Gopinath, 2014. Fabrication of Nanofibers for Dye Degradation. Lambert Academic Publishing, Germany, ISBN: 978-3-659-63721-6, Pages: 64.

  12. Kumar, S.U., I. Matai, P. Dubey, B. Bhushan, A. Sachdev and P. Gopinath, 2014. Differentially cross-linkable core-shell nanofibers for tunable delivery of anticancer drugs: Synthesis, characterization and their anticancer efficacy. RSC Adv., 4: 38263-38272.
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  13. Bhushan, B., S.U. Kumar, I. Matai, A. Sachdev, P. Dubey and P. Gopinath, 2014. Ferritin nanocages: A novel platform for biomedical applications. J. Biomed. Nanotechnol., 10: 2950-2976.
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  14. Sukumar, U.K., B. Bhushan, P. Dubey, I. Matai, A. Sachdev and P. Gopinath, 2013. Emerging applications of nanoparticles for lung cancer diagnosis and therapy. Int. Nano Lett., Vol. 3. 10.1186/2228-5326-3-45.
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  15. Sahni, G., P. Gopinath and P. Jeevanandam, 2013. A novel thermal decomposition approach to synthesize hydroxyapatite-silver nanocomposites and their antibacterial action against GFP-expressing antibiotic resistant E. coli. Colloids Surf. B: Biointerfaces, 103: 441-447.
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  16. Sachdev, A., I. Matai, S.U. Kumar, B. Bhushan, P. Dubey and P. Gopinath, 2013. A novel one-step synthesis of PEG passivated multicolour fluorescent carbon dots for potential biolabeling application. RSC Adv., 3: 16958-16961.
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  17. Kaur, N., N. Choudhary, R.N. Goyal, S. Viladkar and I. Matai et al., 2013. Magnetron sputtered Cu3N/NiTiCu shape memory thin film heterostructures for MEMS applications. J. Nanoparticle Res., Vol. 15. 10.1007/s11051-013-1468-x.
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  18. Bhargavi, G., I. Matai, A. Sachdev, S.U. Kumar and P. Gopinath, 2013. Microwave assisted synthesis of chitosan nanorods and assessment of its antibacterial activity against GFP-expressing antibiotic resistant E. coli. J. Chitin Chitosan Sci., 1: 167-172.
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  19. Yata, V.K., P. Gopinath and S.S. Ghosh, 2012. Emerging implications of nonmammalian cytosine deaminases on cancer therapeutics. Applied Biochem. Biotechnol., 167: 2103-2116.
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  20. Roman, J., T. Rangasamy, J. Guo, S. Sugunan and N. Meednu et al., 2010. T-cell activation under hypoxic conditions enhances IFN-γ secretion. Am. J. Respiratory Cell Mol. Biol., 42: 123-128.
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  21. Packirisamy, G., 2010. Prodrug Gene Therapy Vectors in Combination Therapies: An Update. Lambert Academic Publishing, Germany, ISBN-13: 978-3-8383-4650-2, Pages: 148.

  22. Gopinath, P., S.K. Gogoi, P. Sanpui, A. Paul, A. Chattopadhyay and S.S. Ghosh, 2010. Signaling gene cascade in silver nanoparticle induced apoptosis. Colloids Surf. B: Biointerfaces, 77: 240-245.
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  23. Gopinath, P. and S.S. Ghosh, 2009. Understanding apoptotic signaling pathways in cytosine deaminase-uracil phosphoribosyl transferase-mediated suicide gene therapy in vitro. Mol. Cell. Biochem., 324: 21-29.
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  24. Gopinath, P., S.K. Gogoi, A. Chattopadhyay and S.S. Ghosh, 2008. Implications of silver nanoparticle induced cell apoptosis for in vitro gene therapy. Nanotechnology, Vol. 19. 10.1088/0957-4484/19/7/075104.
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  25. Gopinath, P. and S.S. Ghosh, 2008. Implication of functional activity for determining therapeutic efficacy of suicide genes in vitro. Biotechnol. Lett., 30: 1913-1921.
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  26. Gopinath, P. and S.S. Ghosh, 2008. Apoptotic induction with bifunctional E. Coli cytosine deaminase-uracil phosphoribosyltransferase mediated suicide gene therapy is synergized by curcumin treatment in vitro. Mol. Biotechnol., 39: 39-48.
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  27. Gopinath, P. and S.S. Ghosh, 2007. Monitoring green fluorescent protein for functional delivery of E. Coli cytosine deaminase suicide gene and the effect of curcumin in vitro. Gene Therapy Mol. Biol., 11: 219-228.
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  28. Gogoi, S.K., P. Gopinath, A. Paul, A. Ramesh, S.S. Ghosh and A. Chattopadhyay, 2006. Green fluorescent protein-expressing Escherichia coli as a model system for investigating the antimicrobial activities of silver nanoparticles. Langmuir, 22: 9322-9328.
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  29. Ghosh, S.S., P. Gopinath and A. Ramesh, 2006. Adenoviral vectors: A promising tool for gene therapy. Applied Biochem. Biotechnol., 133: 9-29.
Member since October, 2015