Prof. Dr. Shaukat Iqbal Malik

Professor
Capital University of Science & Technology, Pakistan


Highest Degree
Ph.D. in Biochemistry and Molecular Biology from National and Kapodistrian University of Athens, Greece

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Area of Interest:

Biomedical Sciences
Breast Cancer Research
HIV
Hepatic Amebiasis
Biological Chemistry

Selected Publications

  1. Munir, A., S.I. Malik, S. Aslam, A. Mehmood and S. Amjad et al., 2018. Medicinal plants are effective inhibitors of type I and II diabetes. Pharmacophore, 9: 1-7.
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  2. Munir, A., S.I. Malik and K.A. Malik, 2018. De-novo ligand design against mutated huntington gene by ligand-based pharmacophore modeling approach. Curr. Compu.-Aided Drug Des. 10.2174/1573409915666181207104437.
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  3. Munir, A., I.S. Malik and K. Akhtar, 2018. Proteome mining for the identification of putative drug targets for human pathogen clostridium tetani. Curr. Bioinform., 13: 1-8.

  4. Malik, R.M., F. Nazir, S. Fazal, M. Ullah and S.I. Malik et al., 2018. Computational analysis of dynamical fluctuations of oncoprotein E7 (HPV) for the hot spot residue identification using elastic network Model. bioRxiv 10.1101/401646.
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  5. Khan, M.T., S.I. Malik, S. Ali, A.S. Khan, T. Nadeem et al., 2018. Prevalence of pyrazinamide resistance in Khyber Pakhtunkhwa, Pakistan. Microb. Drug Resist., 24: 1417-1421.
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  6. Khan, M.T., S.I. Malik, A.I. Bhatti, S. Ali and A.S. Khan et al., 2018. Pyrazinamide-resistant mycobacterium tuberculosis isolates from Khyber Pakhtunkhwa and rpsA mutations. J. Biol. Regul. Homeostatic Agents, 32: 705-709.
    PubMed  |  

  7. Khan, M.T., M. Junaid, X. Mao, Y. Wang, A. Hussain, S.I. Malik and D.Q. Wei, 2018. Pyrazinamide resistance and mutations L19R, R140H, and E144K in Pyrazinamidase of Mycobacterium tuberculosis. J. Cell. Biochem., 10.1002/jcb.27989.
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  8. Khan, M.T., A.U. Rehaman, M. Junaid, S.I. Malik and D.Q. Wei, 2018. Insight into novel clinical mutants of RpsA-S324F, E325K and G341R of Mycobacterium tuberculosis associated with pyrazinamide resistance. Comput. Struct. Biotechnol. J., 16: 379-387.
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  9. Junaid, M., M.T. Khan, S.I. Malik and D.Q. Wei, 2018. Insights into the mechanisms of pyrazinamide resistance of three pyrazinamidase mutants N11K, P69T and D126N. J. Chem. Inform. Model. 27. 10.1021/acs.jcim.8b00525.
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  10. hwani, M.N., S. Nisar, A. Aleem, M. Panezai, S. Afridi and S.I. Malik, 2017. Amplification of Mitochondrial DNA for detection of plasmodiumvivax in Balochistan. J. Pak. Med. Assoc., 67: 677-681.
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  11. Noor, T., S. Zubai, A. Gul and S.I. Malik, 2012. Candidate genes prediction in pakistani families with hearing impairment by using bioinformatics approach. Biosci. J., 28: 1024-1033.

  12. Khalid, Z., S. Sameen, S.I. Malik and S. Shehzad, 2012. Computational analysis on the role of GPM6A in human thyroid cancer. J. Data Min. Genom Proteomics, Vol. 3. 10.4172/2153-0602.1000114.
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  13. Kanwal, S., M. Irfan, S.I. Malik and K. Akhtar, 2012. Comparative homology modeling of human rhodopsin with several templates of bovine rhodopsin. OnLine J. Biotechnol., 11: 466-473.

  14. Sameen, S., Z. Khalid and S.I. Malik, 2011. Role of pyruvate dehydrogenase kinases (PDKs) and their respective microRNAs in human ovarian cancer. J. Med. Genet. Genomics, 3: 115-121.
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  15. Malik, S.I., Z. Khalid and S. Sameen, 2011. In silico gene expression based analysis on claudin family members association with human thyroid cancer. J. Proteomics Bioinform., 4: 278-283.
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  16. Malik, S. and S. Khan, 2011. Cancer prevention through employ of appropriate diet in daily schedule. J. Cancer Sci. Ther., Vol. S16. 10.4172/1948-5956.S16-001.
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  17. Hatzi, V.I., G.I. Terzoudi, C. Stavropoulou, S.I. Malik, V. Makropoulos and G.E. Pantelias, 2011. Lack of association between GSTT1 polymorphism and endogenous or benzo[a]pyrene-induced sister chromatid exchanges as analyzed in metaphase or G2-phase lymphocytes. Mol. Biol. Rep., 38: 3959-3966.
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  18. Kligerman, A.D., S.I. Malik and J.A. Campbell, 2010. Cytogenetic insights into DNA damage and repair of lesions induced by a monomethylated trivalent arsenical. Mutat. Res./Genet. Toxicol. Environ. Mutagen., 695: 2-8.
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  19. Malik, S.I., G.I. Terzoudi and G.E. Pantelias, 2004. SCE analysis in G2 lymphocyte prematurely condensed chromosomes after exposure to atrazine: The non-dose-dependent increase in homologous recombinational events does not support its genotoxic mode of action. Cytogenet. Genome Res., 104: 315-319.
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  20. Terzoudi, G.I., S.I. Malik, G.E. Pantelias, K. Marg, K. Manola and W. Makropoulos, 2003. A new cytogenetic approach for the evaluation of mutagenic potential of chemicals that induce cell cycle arrest in the G2 phase. Mutagenesis, 18: 539-543.
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  21. Manola, K.N., G.I. Terzoudi, C.E. Dardoufas, S.I. Malik and G.E. Pandelias, 2003. Radioprotective effect of amifostine on cells from cancer prone patients and healthy individuals studied by the G2 and PCC assays. Int. J. Radiat. Biol., 79: 831-838.
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