Dr. Aisha Mohyuddin

Professor
National University of Medical Sciences, Pakistan

Highest Degree
Ph.D. in Genetic Diversity from Quaid e Azam University, Islamabad, Pakistan

My URL
https://livedna.org/92.30627

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Area of Interest:

Biomedical Sciences
Biotechnology
Gene Mutation
Genetic Variations
Biotechnology of Human Disorders

Selected Publications

  1. Mukarram, O., N. Akhtar, A. Junaid and A. Mohyuddin, 2016. A study into the genetic basis of aspirin resistance in Pakistani patients with coronary artery disease. Pak. J. Pharmaceut. Sci., 29: 1177-1182.
    PubMed  |  

  2. Ullah, M.I., A. Ahmad, S.I. Raza, A. Amar and A. Ali et al., 2015. In silico analysis of SIGMAR1 variant (rs4879809) segregating in a consanguineous Pakistani family showing amyotrophic lateral sclerosis without frontotemporal lobar dementia. Neurogenetics, 16: 299-306.
    CrossRef  |  Direct Link  |  

  3. Shah, S.S., A. Mohyuddin, V. Colonna, S.Q. Mehdi and Q. Ayub, 2015. Monoamine oxidase A gene polymorphisms and self reported aggressive behaviour in a Pakistani ethnic group. J. Pak. Med. Assoc., 65: 818-824.
    Direct Link  |  

  4. Rehman, S., N. Ahmad, N. Akhtar, S. Usman and S. Munir et al., 2015. Mutation screening of MEFV and TNF gene in Pakistani patients with rheumatic heart disease: A case control-study. J. Clin. Cell Immunol., Vol. 6. 10.4172/2155-9899.1000382.
    CrossRef  |  Direct Link  |  

  5. Ayub, Q., M. Mezzavilla, L. Pagani, M. Haber and A. Mohyuddin et al., 2015. The Kalash genetic isolate: Ancient divergence, drift and selection. Am. J. Hum. Genet., 96: 775-783.
    CrossRef  |  Direct Link  |  

  6. Rehman, S., N. Akhtar, N. Saba, S. Munir, W. Ahmed, A. Mohyuddin and A. Khanum, 2013. A study on the association of TNF-α-308, IL-6-174, IL-10-1082 and IL-1RaVNTR gene polymorphisms with rheumatic heart disease in Pakistani patients. Cytokine, 61: 527-531.
    CrossRef  |  Direct Link  |  

  7. Raza, A., S. Firasat, S. Khaliq, A. Abid, S.S. Shah, S.Q. Mehdi and A. Mohyuddin, 2013. HLA class I and II polymorphisms in the Gujjar population from Pakistan. Immunol. Investigat., 42: 691-700.
    CrossRef  |  Direct Link  |  

  8. Underhill, P.A., N.M. Myres, S. Rootsi, M. Metspalu and L.A. Zhivotovsky et al., 2010. Separating the post-glacial coancestry of European and Asian Y chromosomes within haplogroup R1a. Eur. J. Hum. Genet., 18: 479-484.
    CrossRef  |  Direct Link  |  

  9. Li, H., S. Borinskaya, K. Yoshimura, N. Kal'Ina and A. Marusin et al., 2009. Refined geographic distribution of the oriental ALDH2*504Lys (nee 487Lys) variant. Ann. Hum. Genet., 73: 335-345.
    CrossRef  |  Direct Link  |  

  10. Lee, M.Y., N. Mukherjee, A.J. Pakstis, S. Khaliq and A. Mohyuddin et al., 2008. Global patterns of variation in allele and haplotype frequencies and linkage disequilibrium across the CYP2E1 gene. Pharmacogenom. J., 8: 349-356.
    CrossRef  |  Direct Link  |  

  11. Rehman, S., N. Akhtar, W. Ahmad, Q. Ayub, S.Q. Mehdi and A. Mohyuddin, 2007. Human Leukocyte Antigen (HLA) class II association with rheumatic heart disease in Pakistan. J. Heart Valve Dis., 16: 300-304.
    PubMed  |  

  12. Li, H., N. Mukherjee, U. Soundararajan, Z. Tarnok and C. Barta et al., 2007. Geographically separate increases in the frequency of the derived ADH1B*47His allele in Eastern and Western Asia. Am. J. Hum. Genet., 81: 842-846.
    CrossRef  |  Direct Link  |  

  13. Firasat, S., S. Khaliq, A. Mohyuddin, M. Papaioannou, C. Tyler-Smith, P.A. Underhill and Q. Ayub, 2007. Y-chromosomal evidence for a limited Greek contribution to the Pathan population of Pakistan. Eur. J. Hum. Genet., 15: 121-126.
    CrossRef  |  Direct Link  |  

  14. Mohyuddin, A., Q. Ayub, P.A. Underhill, C. Tyler-Smith and S.Q. Mehdi, 2006. Detection of novel Y SNPs provides further insights into Y chromosomal variation in Pakistan. J. Hum. Genet., 51: 375-378.
    CrossRef  |  Direct Link  |  

  15. Barreiro, L.B., H. Quach, J. Krahenbuhl, S. Khaliq and A. Mohyuddin et al., 2006. DC-SIGN interacts with Mycobacterium leprae but sequence variation in this lectin is not associated with leprosy in the Pakistani population. Hum. Immunol., 67: 102-107.
    CrossRef  |  Direct Link  |  

  16. Mohyuddin, A. and S.Q. Mehdi, 2005. HLA analysis of the Parsi (Zoroastrian) population in Pakistan. Tissue Antigens, 66: 691-695.
    PubMed  |  

  17. Khaliq, S., A. Abid, M. Ismail, A. Hameed and A. Mohyuddin et al., 2005. Novel association of RP1 gene mutations with autosomal recessive retinitis pigmentosa. J. Med. Genet., 42: 436-438.
    CrossRef  |  Direct Link  |  

  18. Quintana-Murci, L., R. Chaix, R.S. Wells, D.M. Behar and H. Sayar et al., 2004. Where west meets east: The complex mtDNA landscape of the southwest and Central Asian corridor. Am. J. Hum. Genet., 74: 827-845.
    PubMed  |  

  19. Mohyuddin, A., S. Khaliq, Q. Ayub and S.Q. Mehdi, 2004. HLA-A, -B, -Cw, -DQB1 and -DRB1 allele frequencies in a population from Balochistan province of Pakistan. Hum. Immunol., 65: 1040-1042.
    CrossRef  |  Direct Link  |  

  20. Mohyuddin, A., S. Khaliq, Q. Ayub and S.Q. Mehdi, 2004. HLA-A, -B, -Cw, -DQB1 and -DRB1 allele frequencies in a Sindhi population from Pakistan. Hum. Immunol., 65: 1049-1051.
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  21. Mohyuddin, A., S. Khaliq, Q. Ayub and S.Q. Mehdi, 2004. HLA-A, -B, -Cw, -DQB1 and -DRB1 allele frequencies in a Pathan population from Pakistan. Hum. Immunol., 65: 1047-1049.
    CrossRef  |  Direct Link  |  

  22. Mohyuddin, A., S. Khaliq, Q. Ayub and S.Q. Mehdi, 2004. HLA-A, -B, -Cw, -DQB1 and -DRB1 allele frequencies in a Kalash population from Pakistan. Hum. Immunol., 65: 1045-1047.
    CrossRef  |  Direct Link  |  

  23. Mohyuddin, A., S. Khaliq, Q. Ayub and S.Q. Mehdi, 2004. HLA-A, -B, -Cw, -DQB1 and -DRB1 allele frequencies in a Burusho population from Pakistan. Hum. Immunol., 65: 1042-1044.
    CrossRef  |  Direct Link  |  

  24. Mohyuddin, A., S. Khaliq, Q. Ayub and S.Q. Mehdi, 2004. HLA-A, -B, -Cw, -DQB1 and -DRB1 allele frequencies in a Brahui population from Pakistan. Hum. Immunol., 65: 1038-1040.
    CrossRef  |  Direct Link  |  

  25. Mohyuddin, A., Q. Ayub, S. Siddiqi, D.R. Carvalho-Silva and K. Mazhar et al., 2004. Genetic instability in EBV-transformed lymphoblastoid cell lines. Biochim. Biophys. Acta, 1670: 81-83.
    PubMed  |  

  26. Kayser, M., R. Kittler, A. Erler, M. Hedman and A.C. Lee et al., 2004. A comprehensive survey of human Y-chromosomal microsatellites. Am. J. Hum. Genet., 74: 1183-1197.
    CrossRef  |  Direct Link  |  

  27. Zerjal, T., Y. Xue, G. Bertorelle, R.S. Wells and W. Bao et al., 2003. The genetic legacy of the Mongols. Am. J. Hum. Genet., 72: 717-721.
    CrossRef  |  Direct Link  |  

  28. Mohyuddin, A., F. Williams, A. Mansoor, S.Q. Mehdi and D. Middleton, 2003. Distribution of HLA-A alleles in eight ethnic groups from Pakistan. Tissue Antigens, 61: 286-291.
    CrossRef  |  Direct Link  |  

  29. Khaliq, S., A. Abid, A. Hameed, K. Anwar and A. Mohyuddin et al., 2003. Mutation screening of Pakistani families with congenital eye disorders. Exp. Eye Res., 76: 343-348.
    CrossRef  |  Direct Link  |  

  30. Ayub, Q., A. Mohyuddin, S. Khaliq, A. Hameed, C.T. Smith and S.Q. Mehdi, 2003. DHPLC applications: Finding DNA variation on the Y chromosome. Iran. J. Biotechnol., 1: 26-30.
    Direct Link  |  

  31. Ayub, Q., A. Mansoor, M. Ismail, S. Khaliq and A. Mohyuddin et al., 2003. Reconstruction of human evolutionary tree using polymorphic autosomal microsatellites. Am. J. Phys. Anthropol., 122: 259-268.
    CrossRef  |  Direct Link  |  

  32. Qamar, R., Q. Ayub, A. Mohyuddin, A. Helgason and K. Mazhar et al., 2002. Y-chromosomal DNA variation in Pakistan. Am. J. Hum. Genet., 70: 1107-1124.
    CrossRef  |  Direct Link  |  

  33. Mohyuddin, A., Q. Ayub, S. Khaliq, A. Mansoor, K. Mazhar, S. Rehman and S.Q. Mehdi, 2002. HLA polymorphism in six ethnic groups from Pakistan. Tissue Antigens, 59: 492-501.
    CrossRef  |  Direct Link  |  

  34. Mehdi, S.Q., Q. Ayub, R. Qamar, A. Mohyuddin and A. Mansoor et al., 2002. Perspectives on Human Genome Diversity within Pakistan using Y Chromosomal and Autosomal Microsatellite Markers. In: Biodiversity: Biomolecular Aspects of Biodiversity and Innovative Utilization, Sener, B. (Ed.). Springer, Boston, MA., USA., ISBN: 978-1-4613-4855-9, pp: 35-47.

  35. Khaliq, S., A. Hameed, Q. Ayub, K. Mazhar, A. Mohyuddin, A. Mansoor and S.Q. Mehdi, 2002. Frequency of CCR5 Gene 32-bp deletion in Pakistani ethnic groups. Genet. Test, 6: 123-127.
    PubMed  |  

  36. Quintana-Murci, L., C. Krausz, T. Zerjal, S.H. Sayar and M.F. Hammer et al., 2001. Y-chromosome lineages trace diffusion of people and languages in Southwestern Asia. Am. J. Hum. Genet., 68: 537-542.
    CrossRef  |  Direct Link  |  

  37. Mohyuddin, A., Q. Ayub, R. Qamar, T. Zerjal, A. Helgason, S.Q. Mehdi and C. Tyler-Smith, 2001. Y-chromosomal STR haplotypes in Pakistani populations. Forensic Sci. Int., 118: 141-146.
    CrossRef  |  Direct Link  |  

  38. Scott, H.S., S.E. Antonarakis, L. Mittaz, M.D. Lalioti and F. Younus et al., 2000. Refined genetic mapping of the autosomal recessive non-syndromic deafness locus DFNB8 on human chromosome 21q22.3. Genet. Otorhinolaryngol., 56: 158-163.
    CrossRef  |  Direct Link  |  

  39. Khaliq, S., A. Hameed, T. Khaliq, Q. Ayub and R. Qamar et al., 2000. p53 Mutations, polymorphisms and haplotypes in Pakistani ethnic groups and breast cancer patients. Genet. Testing, 4: 23-29.
    CrossRef  |  Direct Link  |  

  40. Ayub, Q., A. Mohyuddin, R. Qamar, K. Mazhar, T. Zerjal, S.Q. Mehdi and C. Tyler-Smith, 2000. Identification and characterisation of novel human Y-chromosomal microsatellites from sequence database information. Nucleic Acids Res., Vol. 28, No. 2. 10.1093/nar/28.2.e8.
    CrossRef  |  PubMed  |  Direct Link  |  

  41. Mohyuddin, A., Q. Ayub, R. Qamar, S. Khaliq, A. Mansoor and S.Q. Mehdi, 1999. HLA polymorphisms in ethnic groups from Pakistan. Transplant. Proc., 31: 3350-3351.
    CrossRef  |  Direct Link  |  

  42. Veske, A., R. Oehlmann, F. Younus, A. Mohyuddin, B. Muller-Myhsok, S.Q. Mehdi and A. Gal, 1996. Autosomal recessive non-syndromic deafness locus (DFNB8) maps on chromosome 21q22 in a large consanguineous kindred from Pakistan. Hum. Mol. Genet., 5: 165-168.
    CrossRef  |  Direct Link  |  
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