Dr. Usman Ali Ashfaq

Professor
Department of Bioinformatics and Biotechnology, GC University Faisalabad, Faisalabad, Pakistan

Highest Degree
PostDoc. in Molecular Biology from University of the Punjab, Lahore, Pakistan

My URL
https://livedna.org/92.41424

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Area of Interest:

Biological Sciences
Biotechnology
Molecular Biology
Medicinal Plants
Pharmaceutical Sciences

Selected Publications

  1. Khan, G.B., M. Qasim, A. Rasul, U.A. Ashfaq and A.M. Alnuqaydan, 2023. Identification of lignan compounds as new 6-phosphogluconate dehydrogenase inhibitors for lung cancer. Metabolites, Vol. 13. 10.3390/metabo13010034.
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  2. Umar, A., S. Liaquat, I. Fatima, A. Rehman and D. Rasool et al., 2022. Vaccinomics to design a multiepitope vaccine against legionella pneumophila. BioMed Res. Int., Vol. 2022. 10.1155/2022/4975721.
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  3. Tabassum, S., H.R. Khalid, Waqar ul Haq, S. Aslam and A. Alshammari et al., 2022. Implementation of system pharmacology and molecular docking approaches to explore active compounds and mechanism of ocimum sanctum against tuberculosis. Processes, Vol. 10. 10.3390/pr10020298.
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  4. Saddique, F.A., M. Ahmad, U.A. Ashfaq, M. Muddassar, S. Sultan and M.E.A. Zaki, 2022. Identification of cyclic sulfonamides with an N-arylacetamide group as α-glucosidase and α-amylase inhibitors: Biological evaluation and molecular modeling. Pharmaceuticals, Vol. 15. 10.3390/ph15010106.
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  5. Rashid, F., M. Ahmad, U.A. Ashfaq, A.A. Al-Mutairi and S.A. Al-Hussain, 2022. Design, synthesis and pharmacological evaluation of 2-(3-benzoyi-4-hydroxy-1,1-dioxido-2H-benzo[e][1,2]thiazin-2-yI)-N-(2-Bromophenyl) acetamide as antidiabetic agent. Drug Des. Dev. Ther., 16: 4043-4060.
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  6. Rashid, F., A. Javaid, Mahmood-ur-Rahman, U.A. Ashfaq and M. Sufyan et al., 2022. Integrating pharmacological and computational approaches for the phytochemical analysis of Syzygium cumini and its anti-diabetic potential. Molecules, Vol. 27. 10.3390/molecules27175734.
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  7. Noor, F., M. Tahir ul Qamar, U.A. Ashfaq, A. Albutti, A.S.S. Alwashmi and M.A. Aljasir, 2022. Network pharmacology approach for medicinal plants: Review and assessment. Pharmaceuticals, Vol. 15. 10.3390/ph15050572.
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  8. Noor, F., A. Rehman, U.A. Ashfaq, M.H. Saleem and M.K. Okla et al., 2022. Integrating network pharmacology and molecular docking approaches to decipher the multi-target pharmacological mechanism of Abrus precatorius L. acting on diabetes. Pharmaceuticals, Vol. 15. 10.3390/ph15040414.
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  9. Munir, S., M. Khurshid, M. Ahmad, U.A. Ashfaq and M.E.A. Zaki, 2022. Exploring the antimicrobial and pharmacological potential of NF22 as a potent inhibitor of E. coli DNA gyrase: An in vitro and in silico study. Pharmaceutics, Vol. 14. 10.3390/pharmaceutics14122768.
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  10. Khan, I.A., F.A. Saddique, S. Aslam, U.A. Ashfaq, M. Ahmad, S.A. Al-Hussain and M.E.A. Zaki, 2022. Synthesis of novel N-methylmorpholine-substituted benzimidazolium salts as potential α-glucosidase inhibitors. Molecules, Vol. 27. 10.3390/molecules27186012.
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  11. Khalid, H.R., M. Aamir, S. Tabassum, Y.S. Alghamdi, A. Alzamami and U.A. Ashfaq, 2022. Integrated system pharmacology approaches to elucidate multi-target mechanism of Solanum surattense against hepatocellular carcinoma. Molecules, Vol. 27. 10.3390/molecules27196220.
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  12. Khalid, H., S. Khalid, M. Sufyan and U.A. Ashfaq, 2022. In-silico elucidation reveals potential phytochemicals against angiotensin-converting enzyme 2 (ACE-2) receptor to fight coronavirus disease 2019 (COVID-19). Z. Naturforsch. C, 77: 473-482.
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  13. Khalid, H. and U.A. Ashfaq, 2022. Molecular docking and pharmacoinformatics studies reveal potential phytochemicals against HCV NS5B polymerase. Comb. Chem. High Throughput Screening, 25: 335-346.
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  14. Kanwal, A., F. Azeem, H. Nadeem, U.A. Ashfaq and R.M. Aadil et al., 2022. Molecular mechanisms of Cassia fistula against epithelial ovarian cancer using network pharmacology and molecular docking approaches. Pharmaceutics, Vol. 14. 10.3390/pharmaceutics14091970.
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  15. Javaid, A., A. Ijaz, U.A. Ashfaq, M. Arshad, S. Irshad and S. Saif, 2022. An overview of chikungunya virus molecular biology, epidemiology, pathogenesis, treatment and prevention strategies. Future Virol., 17: 593-606.
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  16. Alshammari, A., M. Alharbi, A. Alghamdi, S.A. Alharbi and U.A. Ashfaq et al., 2022. Computer-aided multi-epitope vaccine design against Enterobacter xiangfangensis. Int. J. Environ. Res. Public Health, Vol. 19. 10.3390/ijerph19137723.
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  17. Alshammari, A., A.F. Alasmari, M. Alharbi, N. Ali and Z.T. Muhseen et al., 2022. Novel chimeric vaccine candidate development against Leptotrichia buccalis. Int. J. Environ. Res. Public Health, Vol. 19. 10.3390/ijerph191710742.
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  18. Alamri, M.A., M.U. Mirza, M.M. Adeel, U.A. Ashfaq and M. Tahir ul Qamar et al., 2022. Structural elucidation of rift valley fever virus l protein towards the discovery of its potential inhibitors. Pharmaceuticals, Vol. 15. 10.3390/ph15060659.
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  19. Umar, A., A. Haque, Y.S. Alghamdi, M.M. Mashraqi and A. Rehman et al., 2021. Development of a candidate multi-epitope subunit vaccine against Klebsiella aerogenes: Subtractive proteomics and immuno-informatics approach. Vaccines, Vol. 9. 10.3390/vaccines9111373.
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  20. Tariq, M.H., R. Bhatti, N.F. Ali, U.A. Ashfaq, F. Shahid, A. Almatroudi and M. Khurshid, 2021. Rational design of chimeric multiepitope based vaccine (MEBV) against human T-cell lymphotropic virus type 1: An integrated vaccine informatics and molecular docking based approach. PLoS ONE, Vol. 16. 10.1371/journal.pone.0258443.
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  21. Sufyan, M., F. Shahid, F. Irshad, A. Javaid, M. Qasim and U.A. Ashfaq, 2021. Implementation of vaccinomics and in-silico approaches to construct multimeric based vaccine against ovarian cancer. Int. J. Pept. Res. Ther., 27: 2845-2859.
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  22. Khalid, H., S. Shahid, S. Tariq, B. Ijaz, U.A. Ashfaq and M. Ahmad, 2021. Discovery of Novel HCV NS5B polymerase inhibitor, 2-(3,4-dimethyl-5,5-dioxidobenzo[e]pyrazolo[4,3-c][1,2]thiazin-2(4H)-yl)-N-(2-fluorobenzyl)acetamide via molecular docking and experimental approach. Clin. Exp. Pharmacol. Physiol., 48: 1653-1661.
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  23. Aslam, S., S. Ahmad, F. Noor, U.A. Ashfaq and F. Shahid et al., 2021. Designing a multi-epitope vaccine against Chlamydia trachomatis by employing integrated core proteomics, immuno-informatics and in silico approaches. Biology, Vol. 10. 10.3390/biology10100997.
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  24. Abdur Rehman, X. Wang, S. Ahmad, F. Shahid and S. Aslam et al., 2021. In silico core proteomics and molecular docking approaches for the identification of novel inhibitors against Streptococcus pyogenes. Int. J. Environ. Res. Public Health, Vol. 18. 10.3390/ijerph182111355.
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Member since April, 2023