Dr. El Refaey Hesham

Professor
Batterjee Medical College, Jeddah, Saudi Arabia

Highest Degree
Ph.D. in Pharmacology from University of Nebraska-Lincoln, USA

My URL
https://livedna.org/966.29763

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Area of Interest:

Pharmacology and Toxicology
Drug Toxicology
Tumor Pharmacology
Drug Detection
Toxicity

Selected Publications

  1. Elshinawy, M.I., H.A. Eid, A.A. Khalil, A.M. Soliman and H. El-Refaey, 2018. TNF-α-mediated inflammation and cytotoxicity of different root canal sealers and root-end fillings in cell line culture. Tanta Dental J., 15: 27-32.
    Direct Link  |  

  2. Hafez, E.E., N. El-Deeb, H. El Refaey and W. Botros, 2015. Balanites aegyptiaca extract as anti-hcv and the evidence of the non toxicity on human PBMC cells. AARJMD., 2: 28-41.

  3. Elshinawy, M.I., H.A. Eid, A.A. Khalil, A.M. Soliman and H. El-Refaey, 2015. Matrix metalloproteinase-9-induced inflammatory response to some root end filling and sealant materials in HeLa Epithelial cell line culture. J. Dental Orofacial Res., 11: 18-25.
    Direct Link  |  

  4. Shakor, A.B.A., M. Atia, I.A. Ismail, A. Alshehri, H. El-Refaey, K. Kwiatkowska and A. Sobota, 2014. Curcumin induces apoptosis of multidrug-resistant human leukemia HL60 cells by complex pathways leading to ceramide accumulation. Biochim. Biophys. Acta (BBA)-Mol. Cell Biol. Lipids, 1841: 1672-1682.
    CrossRef  |  Direct Link  |  

  5. Eleawa, S.M., M.A. Alkhateeb, F.H. Alhashem, I. Bin-Jaliah and H.F. Sakr et al., 2014. Resveratrol reverses cadmium chloride-induced testicular damage and subfertility by downregulating p53 and Bax and upregulating gonadotropins and Bcl-2 gene expression. J. Reprod. Dev., 60: 115-127.
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  6. Bashir, S.O., M.D. Morsy, H.F. Sakr, H.M. El Refaey, R.A. Eid, M.A. Alkhateeb and M.A. Defallah, 2014. Quercetin ameliorates diabetic nephropathy in rats via modulation of renal NA+, K+-ATPase expression and oxidative stress. Am. J. Pharmacol. Toxicol., 9: 84-95.
    Direct Link  |  

  7. Aly, A.M., K.M. Al-Akhali, H. Alrefaey and M.A. Shaker, 2014. Formulation and evaluation of fast dissolving gliclazide tablets by complexation with Hydroxypropyl-β-Cyclodextrin. Int. J. Pharm. Sci. Nanotechnol., 7: 2399-2405.

  8. Alhashem, F., M. Alkhateeb, M. Alshahrani, H. Elrefaey and M. Alsunaidi et al., 2014. Exercise protects against obesity induced semen abnormalities via downregulating stem cell factor, upregulating Ghrelin and normalizing oxidative stress. EXCLI J., 13: 551-572.
    PubMed  |  Direct Link  |  

  9. Al-Hashem, F.H., A.S. Assiri, A.S. Shatoor, H.M. Elrefaey, R.M. Alessa and M.A. Alkhateeb, 2014. Increased systemic low-grade inflammation in high altitude native rats mediated by adrenergic receptors. Saudi Med. J., 35: 538-546.
    Direct Link  |  

  10. Sakr, H.F., F.H. Al-Hashem, W.M.H. El-Naby, M.A. Alkhateeb, M.S.A. Zaki, H.M.E. Refaey and M.D. Morsy, 2013. Preventive roles of swimming exercise and pioglitazone treatment on hepatic dysfunction in a rat model of metabolic syndrome. Can. J. Physiol. Pharmacol., 92: 162-170.
    CrossRef  |  Direct Link  |  

  11. Helal, E.G.E., S.M. Abd El-Wahab and H. El Refaey, 2013. Antidiabetic and antihyperlipidemic effect of Balanites aegyptiaca seeds (Aqueous extract) on diabetic rats. Egypt. J. Hospital Med., 52: 725-739.
    CrossRef  |  Direct Link  |  

  12. El Refaey, H. and H.S. Amri, 2011. Effects of antidepressants on behavioral assessment in adolescent rats. Bahrain Med. Bull., 33: 83-89.
    Direct Link  |  

  13. Reed, A.L., J.C. Anderson, D.B. Bylund, F. Petty, H. El Refaey and H.K. Happe, 2009. Treatment with escitalopram but not desipramine decreases escape latency times in a learned helplessness model using juvenile rats. Psychopharmacology, 205: 249-259.
    CrossRef  |  Direct Link  |  

  14. Arafa, H.M.M., H.A.A. Aly, M.F. Abd-Ellah and H.M. El-Refaey, 2009. Hesperidin attenuates benzo [α] pyrene-induced testicular toxicity in rats via regulation of oxidant/antioxidant balance. Toxicol. Ind. Health, 25: 417-427.

  15. El-Refaey, H., H.A. El-Beshbishy, G.M. Morsy and M. El-Shafey, 2008. Role of free radicals and neutrophils in the pathogenesis of gastric mucosal injury induced by meloxicam in rats. Az. J. Pharm. Sci., 38: 124-140.

  16. Sharma, S.K., H. El ReFaey and M. Ebadi, 2006. Complex-1 activity and 18F-DOPA uptake in genetically engineered mouse model of Parkinson's disease and the neuroprotective role of coenzyme Q10. Brain Res. Bull., 70: 22-32.
    CrossRef  |  Direct Link  |  

  17. Ebadi, M., H. Brown-Borg, J. Ren, S. Sharma, S. Shavali, H. El ReFaey and E.C. Carlson, 2006. Therapeutic efficacy of selegiline in neurodegenerative disorders and neurological diseases. Curr. Drug Targets, 7: 1513-1529.
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  18. Ebadi, M., S.K. Sharma, P. Ghafourifar, H. Brown‐Borg and H. El Refaey, 2005. Peroxynitrite in the pathogenesis of Parkinson's disease and the neuroprotective role of metallothioneins. Methods Enzymol., 396: 276-298.
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  19. Ebadi, M., S. Wanpen, S. Shavali, S.K. Sharma and H. El-Refaey, 2005. Coenzyme Q10 Stabilizes Mitochondria in Parkinson’s Disease. In: Molecular Intervention in Life Style-Related Diseases, Hiramatsu, M., T. Yoshikawa and L. Packer (Eds.). Chapter 12, CRC Press, USA., ISBN: 9781420027174, pp: 127-153.

  20. Ebadi, M., H. Brown-Borg, H. El Refaey, B.B. Singh, S. Garrett, S. Shavali and S.K. Sharma, 2005. Metallothionein-mediated neuroprotection in genetically engineered mouse models of Parkinson's disease. Mol. Brain Res., 134: 67-75.
    CrossRef  |  PubMed  |  Direct Link  |  

  21. Basma, H., H. El-Refaey, M.K. Sgagias, K.H. Cowan, X. Luo and P.W. Cheng, 2005. BCL-2 antisense and cisplatin combination treatment of MCF-7 breast cancer cells with or without functional p53. J. Biomed. Sci., 12: 999-1011.
    CrossRef  |  Direct Link  |  

  22. Sharma, S., M. Kheradpezhou, S. Shavali, H. El Refaey, J. Eken, C. Hagen and M. Ebadi, 2004. Neuroprotective actions of coenzyme Q10 in Parkinson's disease. Methods Enzymol., 382: 488-509.
    CrossRef  |  Direct Link  |  

  23. Ebadi, M., S. Sharma, S. Shavali and H. El-Refaey, 2002. Neuroprotective actions of selegiline. J. Neurosci. Res., 67: 285-289.
    CrossRef  |  Direct Link  |  

  24. Ebadi, M., D. Muralikrishnan, P. Govitrapong, J.F. Rodriguiez-Sierra, M.L. Heidrick, I. Ahmed and H. El-Refaey, 2000. Mitochondrial Oxidative Disorders of Aging. In: Anti-oxidants and Free Radicals in Health and Diseases, Marwah, J. and A. Kanthasamy (Eds.). Chapter 15, Prominent Press, Arizona, USA., pp: 301-324.

  25. El Refaey, H., M. Ebadi, C.A. Kuszynski, J. Sweeney, F.M. Hamada and A. Hamed, 1997. Identification of metallothionein receptors in human astrocytes. Neurosci. Lett., 231: 131-134.
    CrossRef  |  Direct Link  |  

  26. Ebadi, M., R.M. Bashir, M.L. Heidrick, F.M. Hamada and E. El Refaey et al., 1997. Neurotrophins and their receptors in nerve injury and repair. Neurochem. Int., 30: 347-374.
    CrossRef  |  Direct Link  |  

  27. Ebadi, M., M.P. Leuschen, H. El Refaey, F.M. Hamada and P. Rojas, 1996. The antioxidant properties of zinc and metallothionein. Neurochem. Int., 29: 159-166.
    CrossRef  |  Direct Link  |  

  28. Hamada, F.M., M.A. Shalaby, A.H. Abdel-Aziz, A. Moustafa, A. EI-Hadi and H. El-Refaey, 1993. Joint O-consumption in experimental gouty arthritis; in vitro and in vivo interaction of commonly used anti-inflammatory drugs with zinc sulfate. Egypt. J. Med. Sci., 14: 443-464.
Member since July, 2019