Dr. Ayman Hussein

Researcher
An-Najah National University, Palestine

Highest Degree
Ph.D. in Biochemistry from University of Hamburg, Germany

My URL
https://livedna.org/970.26404

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Area of Interest:

Biomedical Sciences
Biochemistry Research
Molecular Biology
Parasitology
Immunology

Selected Publications

  1. Burmeister, C., K. Luersen, A. Heinick, A. Hussein, M. Domagalski, R.D. Walter and E. Liebau, 2008. Oxidative stress in Caenorhabditis elegans: Protective effects of the Omega class glutathione transferase (GSTO-1). FASEB J., 22: 343-354.
    CrossRef  |  PubMed  |  Direct Link  |  

  2. Selkirk, M.E., O. Lazari, A.S. Hussein and J.B. Matthews, 2005. Nematode acetylcholinesterases are encoded by multiple genes and perform non-overlapping functions. Chem.-Biol. Interact., 157: 263-268.
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  3. Hussein, A.S., 2005. Inhibition of glutathione biosynthesis by buthionine sulfoximine. An-Najah Univ. J. Res. (N. Sci.), 19: 83-90.

  4. Selkirk, M.E., A.S. Hussein, A.E. Chambers, D. Goulding and M.P. Gares et al., 2004. Trichinella spiralis secretes a homologue of prosaposin. Mol. Biochem. Parasitol., 135: 49-56.
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  5. Lazari, O., A.S. Hussein, M.E. Selkirk, A.J. Davidson, F.J. Thompson and J.B. Matthews, 2003. Cloning and expression of two secretory acetylcholinesterases from the bovine lungworm, Dictyocaulus viviparous. Mol. Biochem. Parasitol., 132: 83-92.
    CrossRef  |  Direct Link  |  

  6. Hussein, A.S., M. Harel and M.E. Selkirk, 2002. A distinct family of acetylcholinesterases is secreted by Nippostrongylus brasiliensis. Mol. Biochem. Parasitol., 123: 125-134.
    CrossRef  |  PubMed  |  Direct Link  |  

  7. Hussein, A.S., K. Kichenin and M.E. Selkirk, 2002. Suppression of secreted acetylcholinesterase expression in Nippostrongylus brasiliensis by RNA interference. Mol. Biochem. Parasitol., 122: 91-94.
    CrossRef  |  PubMed  |  Direct Link  |  

  8. Villatte, F., T.T. Bachman, A.S. Hussein and R.D. Schmid, 2001. Acetylcholinesterase assay for rapid expression screening in liquid and solid media. Biotechniques, 30: 81-86.
    CrossRef  |  Direct Link  |  

  9. Villatte, F., A. Hussein, T. Bachmann and R. Schmid, 2001. Expression level of heterologous proteins in Pichia pastoris is influenced by flask design. Applied Microbiol. Biotechnol., 55: 463-465.
    CrossRef  |  Direct Link  |  

  10. Selkirk, M.E., S.M. Henson, W.S. Russell and A.S. Hussein, 2001. Acetylcholinesterase Secretion by Parasitic Nematodes. In: Parasitic Nematodes-Molecular Biology, Biochemistry and Immunology, Kennedy, M.W. and W. Harnett (Eds.)., CAB International, Wallingford, Oxon, pp: 211-228.

  11. Vella, M., E. Slater, L. Abu-Safieh, A.S. Hussein and P. Greenwell, 2000. The application of databases and PCR in the cloning of glycosidase genes from the protozoan Tritrichomonas foetus. Mol. Biotechnol., 15: 1-10.
    CrossRef  |  Direct Link  |  

  12. Selkirk, M.E. and A.S. Hussein, 2000. Acetylcholinesterases of Gastrointestinal Nematodes. In: Biology of Parasitism: Modern Approaches, Tschudi, C. and E.J. Pearce (Eds.)., Kluwer Academic Publishers, Norwell, MA., pp: 121-142.

  13. Russell, W.S., S.M. Henson, A.S. Hussein, J.R. Tippins and M.E. Selkirk, 2000. Nippostrongylus brasiliensis: Infection induces upregulation of acetylcholinesterase activity on rat intestinal epithelial cells. Exp. Parasitol., 96: 222-230.
    CrossRef  |  Direct Link  |  

  14. Luersen, K., S. Muller, A. Hussein, E. Liebau and R.D. Walter, 2000. The γ-glutamylcysteine synthetase of Onchocerca volvulus. Mol. Biochem. Parasitol., 111: 243-251.
    CrossRef  |  Direct Link  |  

  15. Hussein, A.S., A.M. Smith, M.R. Chacon and M.E. Selkirk, 2000. Determinants of substrate specificity of a second non‐neuronal secreted acetylcholinesterase from the parasitic nematode Nippostrongylus brasiliensis. Eur. J. Biochem., 267: 2276-2282.
    CrossRef  |  Direct Link  |  

  16. Hussein, A.S., M.R. Chacon, A.M. Smith, R. Tosado-Acevedo and M.E. Selkirk, 1999. Cloning, expression and properties of a nonneuronal secreted acetylcholinesterase from the parasitic nematode Nippostrongylus brasiliensis. J. Biol. Chem., 274: 9312-9319.
    CrossRef  |  Direct Link  |  

  17. Hussein, A.S., M.E. Grigg and M.E. Selkirk, 1999. Nippostrongylus brasiliensis: Characterisation of a somatic amphiphilic acetylcholinesterase with properties distinct from the secreted enzymes. Exp. Parasitol., 91: 144-150.
    CrossRef  |  Direct Link  |  

  18. Selkirk, M.E., A.S. Hussein, W.S. Russell, M.E. Grigg and M.R. Chacon et al., 1998. Secreted Acetylcholinesterases from the Nematode Parasite Nippostrongylus brasiliensis: Properties and Implications for Mucosal Immunity. In: Structure and Function of Cholinesterases and Related Proteins, Doctor, B.P., P. Taylor, D.M. Quinn, R.L. Rotundo and M.K. Gentry (Eds.)., Plenum Press, New York, pp: 515-522.

  19. Grigg, M.E., L. Tang, A.S. Hussein and M.E. Selkirk, 1997. Characterisation of monomeric (G1) forms of acetylcholinesterase secreted by Nippostrongylus brasiliensis. Mol. Biochem. Parasitol., 90: 513-524.

  20. Hussein, A.S. and R.D. Walter, 1996. Purification and characterization of γ-glutamyl transpeptidase from Ascaris suum. Mol. Biochem. Parasitol., 77: 41-47.
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  21. Hussein, A.S. and R.D. Walter, 1996. Inhibition of glutathione synthesis of Ascaris suum by buthionine sulfoximine. Parasitol. Res., 82: 372-374.
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  22. Hussein, A.S. and R.D. Walter, 1995. Purification and characterization of γ-glutamylcysteine synthetase from Ascaris suum. Mol. Biochem. Parasitol., 72: 57-64.
    CrossRef  |  Direct Link  |  

  23. Hussein, A.S., S.K. Abdel-Hafez and A.M. Khalil, 1994. Isolation and characterization of excretory/secretory products from in vitro developmental stages of Echinococcus granulosus. Jap. J. Parasitol., 43: 82-89.
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Member since January, 2019