Dr. Mohammed Ibrahim El Said Ali El-Gamal

Associate Professor
Department of Medicinal Chemistry, University of Sharjah, UAE

Highest Degree
Ph.D. in Medicinal Chemistry from Korea Institute of Science and Technology, Korea

My URL
https://livedna.org/971.36364

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Area of Interest:

Biomedical Sciences
Medicinal Chemistry
Biological Sciences
Organic Synthesis
Biomolecular Research

Selected Publications

  1. Zaib, S., I.Khan, H.S. Anbar, Z. Seyed-Omar and R.M. Sbenati et al ., 2022. Evaluation of indole-picolinamide hybrid molecules as carbonic anhydrase-II inhibitors: Biological and computational studies. J. Mol. Struct., Vol. 1262. 10.1016/j.molstruc.2022.133048.
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  2. El-Gamal, M.I., Z. Seyed-Omar, M.M. Madkour and H.S. Anbar, 2022. Evaluation of Substituted Pyrazole-Based Kinase Inhibitors in One Decade (2011–2020): Current Status and Future Prospects. Molecules, Vol. 27. 10.3390/molecules27010330.
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  3. Akbar, N., M.I. El-Gamal, B.Q. Saeed, O.Chang-Hyun and M.S. Abdel-Maksoud et al ., 2022. Antiamoebic Activity of Imidazothiazole Derivatives against Opportunistic Pathogen Acanthamoeba castellanii. Antibiotics, Vol. 11. 10.3390/antibiotics11091183.
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  4. Zaher, D.M., M.I. El‐Gamal, H.A. Omar, S.N. Aljareh and S.A. Al‐Shamma et al ., 2020. Recent advances with alkaline phosphatase isoenzymes and their inhibitors. Arch. Pharm. Vol. 353. 10.1002/ardp.202000011.
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  5. Semreen, M.H., M.I. El-Gamal, S. Abdin, H. Alkhazraji and L. Kamal et al., 2018. Recent updates of marine antimicrobial peptides. Saudi Pharmaceut. J., 26: 396-409.
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  6. Iqbal, J., M.I. El-Gamal, S.A. Ejaz, J. Lecka, J. Sevigny and C.H. Oh, 2018. Tricyclic coumarin sulphonate derivatives with alkaline phosphatase inhibitory effects: In vitro and docking studies. J. Enzyme Inhibit. Med. Chem., 33: 479-484.
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  7. El-Gamal, M.I., S.K. Al-Ameen, D.M. Al-Koumi, M.G. Hamad, N.A. Jalal and C.H. Oh, 2018. Recent advances of Colony-Stimulating Factor-1 Receptor (CSF-1R) kinase and its inhibitors. J. Med. Chem., (In Press). 10.1021/acs.jmedchem.7b00873.
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  8. El-Gamal, M.I., P. Byung-Jun and O. Chang-Hyun, 2018. Synthesis, in vitro antiproliferative activity, and kinase inhibitory effects of pyrazole-containing diarylureas and diarylamides. Eur. J. Med. Chem., 156: 230-239.
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  9. El-Gamal, M.I. and O. Chang-Hyun, 2018. Pyrrolo[3,2-c]pyridine derivatives with potential inhibitory effect against FMS kinase: in vitro biological studies. J. Enzyme Inhib. Med. Chem., 33: 1160-1166.
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  10. Park, B.J., M.I. El-Gamal, W.S. Lee, J.S. Shin, K.H. Yoo, K.T. Lee and C.H. Oh, 2017. Synthesis and inhibitory effects of triarylpyrazoles on LPS-induced NO and PGE2 productions in RAW 264.7 macrophages. Med. Chem. Res., 26: 2161-2171.
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  11. Khan, M.A., M.I. El-Gamal and C.H. Oh, 2017. A progressive review of V600E-B-RAF-dependent melanoma and drugs inhibiting it. Mini-Rev. Med. Chem., 17: 351-365.
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  12. El-Gamal, M.I., M.S. Abdel-Maksoud, M.M. Gamal El-Din, J.S. Shin, K.T. Lee, K.H. Yoo and C.H. Oh, 2017. Synthesis, in vitro antiproliferative and antiinflammatory activities and kinase inhibitory effects of new 1,3,4-triarylpyrazole derivatives. Anti-Cancer Agents Med. Chem., 17: 75-84.
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  13. El-Gamal, M.I., M.A. Khan, H. Tarazi, M.S. Abdel-Maksoud, M.M.G. El-Din, K.H. Yoo and C.H. Oh, 2017. Design and synthesis of new RAF kinase-inhibiting antiproliferative quinoline derivatives. Part 2: Diarylurea derivatives. Eur. J. Med. Chem., 127: 413-423.
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  14. El-Gamal, M.I., I. Brahim, N. Hisham, R. Aladdin, H. Mohammed and A. Bahaaeldin, 2017. Recent updates of carbapenem antibiotics. Eur. J. Med. Chem., 131: 185-195.
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  15. El-Gamal, M.I. and H.S. Anbar, 2017. Recent advances of pyrrolopyridines derivatives: A patent and literature review. Expert Opin. Therapeut. Patents, 27: 591-606.
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Member since July, 2021