Mr. Prakash Parajuli

Research Scholar
Institute of Biomolecule Reconstruction, South Korea


Highest Degree
Ph.D. Student in Biochemistry from Sun Moon Univeristy, South Korea

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Area of Interest:

Molecular Sciences
Secondary Metabolites
Medicinal Chemistry
Biotechnology
Enzymology

Selected Publications

  1. Parajuli, P., R.P. Pandey, S. Darsandhari, Y.I. Park and J.K. Sohng, 2016. Donor substrate flexibility study of AtUGT89C1, a glycosyltransferase from Arabidopsis thaliana. J. Carbohydr. Chem., 35: 367-377.
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  2. Parajuli, P., R.P. Pandey, R.B. Gurung, J.Y. Shin, H.J. Jung, D.H. Kim and J.K. Sohng, 2016. Enzymatic synthesis of lactosylated and sialylated derivatives of epothilone A. Glycoconjugate J., 33: 137-146.
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  3. Pandey, R.P., P. Parajuli, R.B. Gurung and J.K. Sohng, 2016. Donor specificity of YjiC glycosyltransferase determines the conjugation of cytosolic NDP-sugar in in vivo glycosylation reactions. Enzyme Microb. Technol., 91: 26-33.
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  4. Pandey, R.P., P. Parajuli, M.A.G. Koffas and J.K. Sohng, 2016. Microbial production of natural and non-natural flavonoids: Pathway engineering, directed evolution and systems/synthetic biology. Biotechnol. Adv., 34: 634-662.
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  5. Pandey, R.P., P. Parajuli, L.L. Chu, S.Y. Kim and J.K. Sohng, 2016. Biosynthesis of a novel fisetin glycoside from engineered Escherichia coli. J. Ind. Eng. Chem., 43: 13-19.
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  6. Dhakal, D., A.K. Chaudhary, J.S. Yi, A.R. Pokhrel and B. Shrestha et al., 2016. Enhanced production of nargenicin A1 and creation of a novel derivative using a synthetic biology platform. Applied Microbiol. Biotechnol., 100: 9917-9931.
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  7. Parajuli, P., R.P. Pandey, N.T.H. Trang, T.J. Oh and J.K. Sohng, 2015. Expanded acceptor substrates flexibility study of flavonol 7-O-rhamnosyltransferase, AtUGT89C1 from Arabidopsis thaliana. Carbohydr. Res., 418: 13-19.
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  8. Parajuli, P., R.P. Pandey, N.T.H. Trang, A.K. Chaudhary and J.K. Sohng, 2015. Synthetic sugar cassettes for the efficient production of flavonol glycosides in Escherichia coli. Microb. Cell Factories, Vol. 14. 10.1186/s12934-015-0261-1.
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  9. Pandey, R.P., P. Parajuli, L.L. Chu, S. Darsandhari and J.K. Sohng, 2015. Biosynthesis of amino deoxy-sugar-conjugated flavonol glycosides by engineered Escherichia coli. Biochem. Eng. J., 101: 191-199.
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  10. Dhakal, D., T.T. Le, R.P. Pandey, A.K. Jha and R.B. Gurung et al., 2015. Enhanced production of nargenicin A1 and generation of novel glycosylated derivatives. Applied Biochem. Biotechnol., 175: 2934-2949.
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  11. Trang, N.T.H., P. Parajuli, R.P. Pandey, J.H. Lee and J.K. Sohng, 2014. Cloning and expression of N-dimethyl forosamine biosynthesis genes in Escherichia coli. J. Biomol. Reconstr., 11: 164-169.

  12. Trang, N.T.H., P. Parajuli, R.P. Pandey and J.K. Sohng, 2014. Production of Kaempferitrin in Escherichia coli. J. Biomol. Reconstr., 11: 48-54.

  13. Parajuli, P., R.P. Pandey, N.T.H. Trang and J.K. Sohng, 2014. The relative stability and solubility of mupirocin glucoside. J. Biomol. Reconstr., 11: 147-151.

  14. Parajuli, P., R.P. Pandey, N. Koirala, Y.J. Yoon, B.G. Kim and J.K. Sohng, 2014. Enzymatic synthesis of epothilone A glycosides. AMB Express, Vol. 4. 10.1186/s13568-014-0031-1.
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  15. Parajuli, P., R.P. Pandey, A.R. Pokhrel, G.P. Ghimire and J.K. Sohng, 2014. Enzymatic glycosylation of the topical antibiotic mupirocin. Glycoconjugate J., 31: 563-572.
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  16. Pandey, R.P., R.B. Gurung, P. Parajuli, N. Koirala and J.K. Sohng, 2014. Assessing acceptor substrate promiscuity of YjiC-mediated glycosylation toward flavonoids. Carbohydr. Res., 393: 26-31.
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  17. Pandey, R.P., P. Parajuli, N. Koirala, J.H. Lee, Y.I. Park and J.K. Sohng, 2014. Glucosylation of isoflavonoids in engineered Escherichia coli. Mol. Cells, 37: 172-177.
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  18. Koirala, N., R.P. Pandey, P. Parajuli, H.J. Jung and J.K. Sohng, 2014. Methylation and subsequent glycosylation of 7,8-dihydroxyflavone. J. Biotechnol., 184: 128-137.
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  19. Pokhrel, A.R., R.P. Pandey, P. Parajuli, A.K. Chaudhary, D. Dhakal and J.K. Sohng, 2013. An attempt to enhance the solubility of Violacein by generating glucoside analaogues. J. Biomol. Reconstr., 10: 100-106.

  20. Parajuli, P., R.P. Pandey, N.T.H. Trang and J.K. Sohng, 2013. Enzymatic synthesis of 8-hydroxyquinoline glucoside. J. Biomol. Reconstr., 10: 126-131.

  21. Parajuli, P., R.P. Pandey, K. Liou and J.K. Sohng, 2013. Modification of 1,4-dihydroxybenzene by glycosylation. J. Biomol. Reconstr., 10: 58-64.

  22. Pandey, R.P., P. Parajuli, N. Koirala, J.W. Park and J.K. Sohng, 2013. Probing 3-hydroxyflavone for in vitro glycorandomization of flavonols by YjiC. Applied Environ. Microbiol., 79: 6833-6838.
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  23. Pandey, R.P., P. Parajuli, J.H. Lee and J.K. Sohng, 2013. In vitro glucosylation of rhodomycinone. J. Biomol. Reconstr., 10: 52-57.

  24. Parajuli, P., R.P. Pandey and J.K. Sohng, 2012. In vitro glycosylation of mupirocin. J. Biomol. Reconstr., 9: 139-145.

  25. Pandey, R.P., N. Koirala, P. Parajuli, J.H. Lee and J.K. Sohng, 2012. Scale-up in vivo glycosylation by fermentation. J. Biomol. Reconstr., 9: 43-49.