Dr. Mohammad Taher Boroushaki

Professor
Mashhad University of Medical Sciences, Iran


Highest Degree
Ph.D. in Toxicology from University of Surrey, UK

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Area of Interest:

Biomedical Sciences
Nephrotoxicity
Neurotoxicity
Medicinal Plants
Antioxidants

Selected Publications

  1. Hatamluyi, B., M. Rezayi, H.R. Beheshti and M.T. Boroushaki, 2020. Ultra-sensitive molecularly imprinted electrochemical sensor for patulin detection based on a novel assembling strategy using Au@Cu-MOF/N-GQDs. Sensors Actuators B: Chem., 10.1016/j.snb.2020.128219.
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  2. Arshadi, D., Y. Shakiba, A. Rajabian, B. Nikbin, S.H. Mousavi and M.T. Boroushaki, 2020. Cholinergic agonists inhibit proliferation of human fibroblast-like synoviocytes and monocytic cell lines and reduce VEGF and MMPs expression by these cells. Immunopharmacol. Immunotoxicol., 42: 246-254.
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  3. Rajabian, A., H.R. Sadeghnia, A. Hosseini, S.H. Mousavi and M.T. Boroushaki, 2019. 3‐Acetyl‐11‐keto‐β‐boswellic acid attenuated oxidative glutamate toxicity in neuron‐like cell lines by apoptosis inhibition. J. Cell Biochem., 121: 1778-1789.
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  4. Almeida, J.B., 2019. Bladder endometriosis an improbable cause of hematuri. JOJ Urol. Nephro., 10.19080/JOJUN.2017.04.555640.
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  5. Boroushaki, M.T., A. Hosseini, S. Fanoudi, H. Mollazadeh and A. Aghaei, 2018. Protective effect of Rheum turkestanicum against cisplatin by reducing oxidative stress in kidney tissue. J. Pharm. Bioall. Sci., 10: 66-71.
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  6. Moradi, A., F. Ghasemi, K. Anvari, S.M. Hassanian and S.A. Simab et al., 2017. The cross-regulation between SOX15 and wnt signaling pathway. J. Cell Physiol., 232: 3221-3225.
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  7. Mollazadeh, H., M.T. Boroushaki, M. Soukhtanloo, A.R. Afshari and M. Vahedi, 2017. Effects of pomegranate seed oil on oxidant/antioxidant balance in heart and kidney homogenates and mitochondria of diabetic rats and high glucose-treated H9c2 cell line. Avecina J. Phytomed., 7: 317-333.

  8. Bihamta, M., A. Hosseini, A. Ghorbani and M.T. Boroushaki, 2017. Protective effect of pomegranate seed oil against H2O2-induced oxidative stress in cardiomyocytes. Avicenna J. Phytomed., 7: 46-53.
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  9. Bazmandegan, G., M.T. Boroushaki, A. Shamsizadeh, F. Ayoobi, E. Hakimizadeh and M. Allahtavakoli, 2017. Brown propolis attenuates cerebral ischemia-induced oxidative damage via affecting antioxidant enzyme system in mice. Biomed. Pharmacother., 85: 503-510.
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  10. Rajabian, A., M.T. Boroushaki, P. Hayatdavoudi and H.R. Sadeghnia, 2016. Boswellia serrata protects against glutamate-induced oxidative stress and apoptosis in PC12 and N2a cells. DNA Cell Biol., 35: 666-679.
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  11. Mollazadeh, H., H.R. Sadeghnia, A. Hoseini, M. Farzadnia and M.T. Boroushaki, 2016. Effects of pomegranate seed oil on oxidative stress markers, serum biochemical parameters and pathological findings in kidney and heart of streptozotocin-induced diabetic rats. Renal Fail., 38: 1256-1266.
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  12. Mashmoul, M., A. Azlan, N. Mohtarrudin, B.N.M. Yusof and H. Khaza’ai et al., 2016. Protective effects of saffron extract and crocin supplementation on fatty liver tissue of high-fat diet-induced obese rats. BMC Complementary Altern. Med., Vol. 16. 10.1186/s12906-016-1381-9.
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  13. Jamshidi, S., M. Lahouti, M.T. Boroushaki, A. Ganjeali, A. Ghorbani and M.B. Toosi, 2016. Protective effect of diosgenin against H2O2-induced oxidative stress on H9C2 cells. J. Cell Mol. Res., 8: 58-64.
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  14. Boroushaki, M.T., H. Mollazadeh and A.R. Afshari, 2016. Pomegranate seed oil: A comprehensive review on its therapeutic effects. Int. J. Pharmaceut. Sci. Res., 7: 1000-1013.

  15. Boroushaki, M.T., A. Hosseini, K. Dolati, H. Mollazadeh and A. Rajabian, 2016. Protective effect of pomegranate seed oil against mercuric chloride-induced hepatotoxicity in rat. Acta Poloniae Pharm. Drug Res., 73: 991-997.
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  16. Bakhtiari, E., A. Hosseini, M.T. Boroushaki and S.H. Mousavi, 2016. Angiotensin II receptor antagonist olmesartan and NF-kappaB inhibitor as cytotoxic and apoptotic agents in MCF-7 human cell line. J. Chemother., 28: 314-320.
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  17. Asadpour, E., H.R. Sadeghnia, A. Ghorbani, M. Sedaghat and M.T. Boroushaki, 2016. Oxidative stress-mediated cytotoxicity of zirconia nanoparticles on PC12 and N2a cells. J. Nanoparticle Res., Vol. 18. 10.1007/s11051-015-3316-7.
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  18. Boroushaki, M.T., A. Rajabian, M. Farzadnia, A. Hoseini and M. Poorlashkari et al., 2015. Protective effect of pomegranate seed oil against cisplatin-induced nephrotoxicity in rat. Renal Failure, 37: 1338-1343.
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  19. Bakhtiari, E., A. Hosseini, M.T. Boroushaki and S.H. Mousavi, 2015. Synergistic, cytotoxic and apoptotic activities of olmesartan with NF-κB inhibitor against HeLa human cell line. Toxicol. Mech. Methods, 25: 614-621.
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  20. Oliaee, D., M.T. Boroushaki, N. Oliaee and A. Ghorbani, 2014. Evaluation of cytotoxicity and antifertility effect of Artemisia kopetdaghensis. Adv. Pharmacol. Sci. 10.1155/2014/745760.
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  21. Mashmoul, M., A. Azlan, B.N.M. Yusof, H. Khaza'ai, N. Mohtarrudin and M.T. Boroushaki, 2014. Effects of saffron extract and crocin on anthropometrical, nutritional and lipid profile parameters of rats fed a high fat diet. J. Functional Foods, 8: 180-187.
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  22. Boroushaki, M.T., H. Mollazadeh, A. Rajabian, K. Dolati, A. Hoseini, M. Paseban and M. Farzadnia, 2014. Protective effect of pomegranate seed oil against mercuric chloride-induced nephrotoxicity in rat. Renal Failure, 36: 1581-1586.
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  23. Asadpour, E., H.R. Sadeghnia, A. Ghorbani and M.T. Boroushaki, 2014. Effect of zirconium dioxide nanoparticles on glutathione peroxidase enzyme in PC12 and N2a cell lines. Iran. J. Pharmaceut. Res., 13: 1141-1148.
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  24. Salari, R., M.B.H. Najafi, M.T. Boroushaki, S.A. Mortazavi and M.F. Najafi, 2013. Aflatoxins and ochratoxin a contamination in Iranian red pepper after harvesting. J. Food Sci. Technol., 41: 47-57.

  25. Sadeghnia, H.R., M. Kamkar, E. Assadpour, M.T. Boroushaki and A. Ghorbani, 2013. Protective effect of safranal, a constituent of Crocus sativus, on quinolinic acid-induced oxidative damage in rat hippocampus. Iran. J. Basic Med. Sci., 16: 73-82.
    PubMed  |  

  26. Sadeghnia, H.R., B.S. Yousefsani, M. Rashidfar, M.T. Boroushaki, E. Asadpour and A. Ghorbani, 2013. Protective effect of rutin on hexachlorobutadiene-induced nephrotoxicity. Renal Failure, 35: 1151-1155.
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  27. Bouroshaki, M.T., D. Arshadi, H. Jalili-Rastib, E. Asadpour and A. Hosseini, 2013. Protective effect of pomegranate seed oil against acute toxicity of diazinon in rat kidney. Iran J. Pharm. Res., 12: 821-827.
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  28. Arshadi, D., B. Nikbin, Y. Shakiba, A. Kiani, A.R. Jamshidi and M.T. Boroushaki, 2013. Plasma level of neopterin as a marker of disease activity in treated rheumatoid arthritis patients: Association with gender, disease activity and anti-CCP antibody. Int. Immunopharmacol., 17: 763-767.
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  29. Salari, R., M.B.H. Najafi, M.T. Boroushaki, S.A. Mortazavi and M.F. Najafi, 2012. Assessment of the microbiological quality and mycotoxin contamination of Iranian red pepper spice. J. Agric. Sci. Technol., 14: 1511-1521.
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  30. Salari, R., M.B.H. Najafi, M.T. Boroushaki, S.A. Mortazavi and M.F. Najafi, 2012. A comparison between ELISA and HPLC for aflatoxin B1 and ochratoxin a detection in Iranian red pepper. J. Food Ind. Res., 21: 482-490.

  31. Boroushaki, M.T., E. Asadpour, H.R. Sadeghnia and K. Dolati, 2012. Effect of pomegranate seed oil against gentamicin-induced nephrotoxicity in rat. J. Food Sci. Technol., 51: 3510-3514.
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  32. Rad, A.K., L. Ghazi, M.T. Boroushaki, A. Khooei and Z. Keshavarzi et al., 2011. Effect of commercial (vimang) and hydroalcoholic extract of Mangifera indica (Mango) on gentamicin-induced nephrotoxicity in rat. Avicenna J. Phytomed., 1: 98-105.

  33. Mahmoudian, A., M.T. Boroushaki, A. Moghimi and M. Jafarpur, 2010. Study of emotional and exploratory behaviors in the first generation of morphine addicted mice using open field and relative plus maze. Pharmacology, 3: 208-216.

  34. Bouroshaki, M.T., H.R. Sadeghnia, M. Banihasan and S. Yavari, 2010. Protective effect of pomegranate seed oil on hexachlorobutadiene-induced nephrotoxicity in rat kidneys. Renal Failure, 32: 612-617.
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  35. Boroushaki, M.T., E. Nikkhah, A. Kazemi, M. Oskooei and M. Raters, 2010. Determination of acrylamide level in popular Iranian brands of potato and corn products. Food Chem. Toxicol., 48: 2581-2584.
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  36. Boroushaki, M.T. and H.R. Sadeghnia, 2009. Protective effect of safranal against gentamicin-induced nephrotoxicity in rat. Iran. J. Med. Sci., 34: 285-288.
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  37. Naghizadeh, B., M.T. Boroushaki, N. Vahdati Mashhadian and M.T. Mansouri, 2008. Protective effects of crocin against cisplatin-induced acute renal failure and oxidative stress in rats. Iran. Biomed. J., 12: 93-100.
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  38. Boroushaki, M.T., H. Mofidpour and H.R. Sadeghnia, 2007. Protective effect of safranal against hexachorobutadiene-induced nephrotoxicity in rat. Iran J. Med. Sci., 32: 173-176.

  39. Mahmoodian, A.R., M.T. Boroushaki, F. Molkizadeh, 2006. Assessment of some complications in male mice-addicted to morphine on first generation of offspring. Iran. J. Basic Med. Sci., 9: 50-56.

  40. Sadeghnia, H.R., M.T. Boroushaki and H. Mofidpour, 2005. Effect of safranal on lipid peroxidation level during renal ischemia-reperfusion injury in rat. Iran J. Basic Med. Sci., 8: 179-185.

  41. Boroushaki, M.T., H.R. Sadeghnia and H. Mofidpour, 2005. Protective effect of calcium channel blockers against hexachorobutadiene nephrotoxicity in rat. Iran J. Basic Med. Sci., 7: 208-214.
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  42. Rakhshandeh, H., M.T. Boroushaki, H. Parsaee and A. Sadeghian, 2004. Antimicrobial effect of different extracts of Nerium oleander L on standard and clinically isolated microorganism. Koomesh J. Semnan Univ., 6: 37-42.

  43. Malek, F., M.H. Boskabady, M.T. Borushaki and M. Tohidi, 2004. Bronchodilatory effect of Portulaca oleracea in airways of asthmatic patients. J. Ethnopharmacol., 93: 57-62.
    PubMed  |  

  44. Boroushaki, M.T., M.H. Boskabady and F. Malek, 2004. Antitussive effect of Portulaca oleracea L. in guinea pigs. Iran. J. Pharmaceut. Res., 3: 187-190.
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  45. Boroushaki, M.T., H. Mofidpour and K. Doulati, 2004. Protective effects of verapamil against hexachlorobutadiene nephrotoxicity in rat. Iran. J. Med. Sci., 29: 101-104.

  46. Boroushaki, M.T., F. Malek and A. Baharloo, 2004. Anticonvulsant effects of Melissa officinalis in mice. J. Gilan Univ., 48: 14-20.

  47. BoBoskabady, M.H., M.T. Boroushaki and M.R. Aslani, 2004. Relaxant effect of Portulaca oleraceae on guinea pig tracheal chains and its possible mechanism (s) of action. Med. Hypotheses Res., 1: 139-147.
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  48. Boroushaki, M.T., P. Grasso and P.S. Goldfarb, 2003. Neurotoxic effects of hexachlorobutadiene on the young male rat. Iran. J. Basic Med. Sci., 6: 126-131.

  49. Boroushaki, M.T., 2003. Development of resistance against hexachlorobutadiene in the proximal tubules of young male rat. Comp. Biochem. Physiol. C: Toxicol. Pharmacol., 136: 367-375.
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  50. Boroushaki, M.T., F. Malek and A. Baharloo, 2000. Anticonvulsant effects of Rosmarinus officinalis in mice. Koomesh J. Semnan Univ., 3: 53-58.