Dr. Mohammad Sadegh Soltani-Zangbar

Laboratory Assistant
Department of Immunology, Tabriz University of Medical Sciences, Tabriz, Iran


Highest Degree
Ph.D. in Medical Immunology from Tabriz University of Medical Sciences, Tabriz, Iran

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Area of Interest:

Biomedical Sciences
Molecular Cell Biology
Immunology
Immunotoxicity
Gastroenterology

Selected Publications

  1. Maleki, M.A., A.M. Mahdavi, M.S. Soltani-Zangbar, M. Yousefi and A. Khabbazi, 2023. Randomized double-blinded controlled trial on the effect of synbiotic supplementation on IL-17/IL-23 pathway and disease activity in patients with axial spondyloarthritis. Immunopharmacol. Immunotoxicol., 45: 43-51.
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  2. Yousefzadeh, Y., M.S. Soltani-Zangbar, M. Hemmatzadeh, N. Shomali, A. Mahmoodpoor, J.A. Heris and M. Yousefi, 2022. Fetomaternal immune tolerance: Crucial mechanisms of tolerance for successful pregnancy in humans. Immunol. Invest., 51: 1108-1125.
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  3. Yousefzadeh, Y., M.S. Soltani-Zangbar, L. Kalafi, A. Tarbiat and S.S. Farid et al., 2022. Evaluation of CD39, CD73, HIF-1α, and their related miRNAs expression in decidua of preeclampsia cases compared to healthy pregnant women. Mol. Biol. Rep., 49: 10183-10193.
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  4. Soltani-Zangbar, M.S., F. Parhizkar, M. Abdollahi, N. Shomali, L. Aghebati-Maleki et al., 2022. Immune system-related soluble mediators and COVID-19: Basic mechanisms and clinical perspectives. Cell Commun. Signal, Vol. 20. 10.1186/s12964-022-00948-7.
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  5. Soltani-Zangbar, M.S., F. Parhizkar, E. Ghaedi, A. Tarbiat, R. Motavalli et al., 2022. A comprehensive evaluation of the immune system response and type-I Interferon signaling pathway in hospitalized COVID-19 patients. Cell Commun. Signal, Vol. 20. 10.1186/s12964-022-00903-6.
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  6. Soltani-Zangbar, M.S., A. Mahmoodpoor, S. Dolati, A. Shamekh, S. Valizadeh, M. Yousefi and S. Sanaie, 2022. Serum levels of vitamin D and immune system function in patients with COVID-19 admitted to intensive care unit. Gene Rep., Vol. 26. 10.1016/j.genrep.2022.101509.
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  7. Shafiei, S.L., A. Movassaghpour, S.F. Hosseini, M. Talebi and M. Edalati et al., 2022. The altered expression of homing factors in CD34+ hematopoietic stem cells following G-CSF injection and its effects on transplantation quality in ALL patients. Cell Biol. Int., 46: 1876-1885.
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  8. Pourakbari, R., F. Parhizkar, M.S. Soltani-Zangbar, P. Samadi and M. Zamani et al., 2022. Preeclampsia-derived exosomes imbalance the activity of Th17 and Treg in PBMCs from Healthy pregnant women. Reprod. Sci., 10.1007/s43032-022-01059-x.
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  9. Omidvar, M.H., M.S. Soltani-Zangbar, M. Zamani, R. Motavalli and M. Jafarpoor et al., 2022. The effect of osteoporotic and non-osteoporotic individuals' T cell-derived exosomes on osteoblast cells' bone remodeling related genes expression and alkaline phosphatase activity. BMC Res. Notes, Vol. 15. 10.1186/s13104-022-06139-4.
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  10. Nouri, N., O. Shareghi-Oskoue, L. Aghebati-Maleki, S. Danaii and J.A. Heris, 2022. Role of miRNAs interference on ovarian functions and premature ovarian failure. Cell. Commun. Signal, Vol. 20. 10.1186/s12964-022-00992-3.
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  11. Markazi, R., M.S. Soltani-Zangbar, M. Zamani, S. Eghbal-Fard and R. Motavalli et al., 2022. Platelet lysate and tendon healing: Comparative analysis of autologous frozen-thawed PRP and ketorolac tromethamine in the treatment of patients with rotator cuff tendinopathy. Growth Factors, 40: 163-174.
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  12. Kamrani, A., M.S. Soltani-Zangbar, S. Shiri, Y. Yousefzadeh and R. Pourakbari et al., 2022. TIGIT and CD155 as immune-modulator receptor and ligand on CD4+ T cells in preeclampsia patients. Immunol. Invest., 51: 1023-1038.
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  13. Jafarpour, M., M.H. Omidvar, M.S. Soltani-Zangbar, S. Dolati and M. Ahmadi et al., 2022. The effects of PBMCs-derived exosomes of ankylosing spondylitis patients on T cell profiles. Gene Rep., Vol. 26. 10.1016/j.genrep.2021.101446.
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  14. Gholipour, E., H. Kahroba, N. Soltani, P. Samadi and P. Sarvarian et al., 2022. Paediatric pre-B acute lymphoblastic leukaemia-derived exosomes regulate immune function in human T cells. J. Cell. Mol. Med., 26: 4566-4576.
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  15. Ghasempour, M., M. Hosseini, M.S. Soltani-Zangbar, R. Motavalli and L. Aghebati-Maleki et al., 2022. The impact of hyssop (Hyssopus officinalis) extract on activation of endosomal toll like receptors and their downstream signaling pathways. BMC Res. Notes, Vol. 15. 10.1186/s13104-022-06253-3.
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  16. GBD 2019 LRI Collaborators, 2022. Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: Results from the global burden of disease study 2019. Lancet Infect. Dis., 22: 1626-1647.
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  17. GBD 2019 Cancer Risk Factors Collaborators, 2022. The global burden of cancer attributable to risk factors, 2010–19: A systematic analysis for the global burden of disease study 2019. Lancet, 400: 563-591.
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  18. Farzaneh, R., A. Khabbazi, M.S. Soltani-Zangbar, S. Abbasian, A.M. Mahdavi, R. Motavalli and M. Yousefi, 2022. Effects of nanocurcumin supplementation on T-helper 17 cells inflammatory response in patients with Behcet’s disease: A randomized controlled trial. Immunopharmacol. Immunotoxicol., 44: 206-215.
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  19. Etemadi, J., S. Bordbar, M.S. Soltani-Zangbar, M. Hajivalili and L. Aghebati-Maleki et al., 2022. Prevalence of SARS-CoV-2 Specific antibodies in asymptomatic hemodialysis patients. Immunol. Invest., 51: 993-1004.
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  20. Alizadegan, A., M. Akbarzadeh, M.S. Soltani-Zangbar and R. Sambrani et al., 2022. Isolation of cfDNA from spent culture media and its association with implantation rate and maternal immunomodulation. BMC Res. Notes, Vol. 15. 10.1186/s13104-022-06151-8.
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  21. Zolfaghari, M.A., R. Motavalli, M.S. Soltani-Zangbar, F. Parhizkar and S. Danaii et al., 2021. A new approach to the preeclampsia puzzle; MicroRNA-326 in CD4+ lymphocytes might be as a potential suspect. J. Reprod. Immunol., Vol. 145. 10.1016/j.jri.2021.103317.
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  22. Vahidnezhad, H., L. Youssefian, A.H. Saeidian, V. Ziaee and H. Mahmoudi et al., 2021. Homozygous MEFV gene variant and pyrin-associated autoinflammation with neutrophilic dermatosis: A family with a novel autosomal recessive mode of inheritance. JAMA Dermatol., 157: 1466-1471.
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  23. Soltani-Zangbar, M.S., L. Aghebati-Maleki, M. Hajivalili, M. Haji-Fatahaliha and R. Motavalli et al., 2021. Application of newly developed SARS-CoV2 serology test along with real-time PCR for early detection in health care workers and on-time plasma donation. Gene Rep., Vol. 23. 10.1016/j.genrep.2021.101140.
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  24. Motavalli, R., J. Etemadi, M.S. Soltani-Zangbar, M.R. Ardalan and H. Kahroba et al., 2021. Altered Th17/Treg ratio as a possible mechanism in pathogenesis of idiopathic membranous nephropathy. Cytokine, Vol. 141. 10.1016/j.cyto.2021.155452.
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  25. Mahmoodpoor, A., M. Hosseini, S. Soltani-Zangbar, S. Sanaie and L. Aghebati-Maleki et al., 2021. Reduction and exhausted features of T lymphocytes under serological changes, and prognostic factors in COVID-19 progression. Mol. Immunol., 138: 121-127.
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  26. Alvarez, E.M., L.M. Force, R. Xu, K. Compton and D. Lu et al., 2021. The global burden of adolescent and young adult cancer in 2019: A systematic analysis for the Global Burden of Disease Study 2019. Lancet Oncol., 23: 27-52.
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  27. Abbasian, S., M.S. Soltani-Zangbar, A. Khabbazi, R. Farzaneh and A.M. Mahdavi et al., 2021. Nanocurcumin supplementation ameliorates Behcet’s disease by modulating regulatory T cells: A randomized, double‐blind, placebo-controlled trial. Int. Immunopharmacol., Vol. 101. 10.1016/j.intimp.2021.108237.
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  28. Shomali, N., M. Hemmatzadeh, Y. Yousefzadeh, M.S. Soltani-Zangbar, K. Hamdi, A. Mehdizadeh and M. yousefi, 2020. Exosomes: Emerging biomarkers and targets in folliculogenesis and endometriosis. J. Reprod. Immunol., Vol. 142. 10.1016/j.jri.2020.103181.
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  29. Pourmoghadam, Z., M.S. Soltani-Zangbar, G. Sheikhansari, R. Azizi and S. Eghbal-Fard et al., 2020. Intrauterine administration of autologous hCG- activated peripheral blood mononuclear cells improves pregnancy outcomes in patients with recurrent implantation failure; A double-blind, randomized control trial study. J. Reprod. Immunol., Vol. 142. 10.1016/j.jri.2020.103182.
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  30. Pishgahi, A., R. Abolhasan, S.K. Shakouri, M.S. Soltani-Zangbar and S. Dareshiri et al., 2020. Effect of dextrose prolotherapy, platelet rich plasma and autologous conditioned serum on knee osteoarthritis: A randomized clinical trial. Iran. J. Allergy AsthmaImmunol., 19: 243-252.
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  31. Pishgahi, A., R. Abolhasan, S. Danaii, B. Amanifar and M.S. Soltani-Zangbar et al., 2020. Immunological and oxidative stress biomarkers in Ankylosing Spondylitis patients with or without metabolic syndrome. Cytokine, Vol. 128. 10.1016/j.cyto.2020.155002.
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  32. Javadian, M., N. Shekari, M.S. Soltani-Zangbar, A. Mohammadi and B. Mansoori et al., 2020. Docosahexaenoic acid suppresses migration of triple-negative breast cancer cell through targeting metastasis-related genes and microRNA under normoxic and hypoxic conditions. J. Cell. Biochem., 121: 2416-2427.
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  33. Danaii, S., R. Abolhasani, M.S. Soltani-Zangbar, M. Zamani and A. Mehdizadeh et al., 2020. Oxidative stress and immunological biomarkers in Ankylosing spondylitis patients. Gene Rep., Vol. 18. 10.1016/j.genrep.2019.100574.
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  34. Danaii, S., F. Ghorbani, M. Ahmadi, H. Abbaszadeh and L. Koushaeian et al., 2020. IL-10-producing B cells play important role in the pathogenesis of recurrent pregnancy loss. Int. Immunopharmacol., Vol. 87. 10.1016/j.intimp.2020.106806.
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  35. Aslan, C., S. Maralbashi, H. Kahroba, M. Asadi and M.S. Soltani-Zangbar et al., 2020. Docosahexaenoic acid (DHA) inhibits pro-angiogenic effects of breast cancer cells via down-regulating cellular and exosomal expression of angiogenic genes and microRNAs. Life Sci., Vol. 258. 10.1016/j.lfs.2020.118094.
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  36. Zolbanin, N.M., R. Jafari, J. Majidi, F. Atyabi and M. Yousefi et al., 2019. Apoptotic effects of Mucin1 aptamer-conjugated nanoparticles containing docetaxel and c-Met siRNA on SKBR3 human metastatic breast cancer cells. Jundishapur J. Nat. Pharm. Prod., Vol. 14. 10.5812/jjnpp.67023.
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  37. Sheikhansari, G., M.S. Soltani-Zangbar, Z. Pourmoghadam, A. Kamrani and R. Azizi et al., 2019. Oxidative stress, inflammatory settings, and microRNA regulation in the recurrent implantation failure patients with metabolic syndrome. Am. J. Reprod. Immunol., Vol. 82. 10.1111/aji.13170.
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  38. Mortazavi, H., M.S. Soltani-Zangbar, S. Eghbal-Fard, A. Mehdizadeh and A. Kamrani et al., 2019. Cytokine profile, Treg/Th17 cell frequency changes during different posttransplantational time points in patients undergoing renal transplantation. J. Cell. Physiol., 234: 20935-20943.
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  39. Azizi, R., M.S. Soltani-Zangbar, G. sheikhansari, Z. Pourmoghadam and A. Mehdizadeh et al. 2019. Metabolic syndrome mediates inflammatory and oxidative stress responses in patients with recurrent pregnancy loss. J. Reprod. Immunol., 133: 18-26.
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  40. Zolbanin, N.M., R. Jafari, J. Majidi, F. Atyabi and M. Yousefi et al., 2018. Targeted co-delivery of docetaxel and cMET siRNA for treatment of mucin1 overexpressing breast cancer cells. Adv. Pharm. Bull., 8: 383-393.
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  41. Zangbar, M.S.S., S. Keshtgar, J. Zolghadri and B. Gharesi-Fard, 2016. Antisperm protein targets in azoospermia men. J. Hum. Reprod. Sci., 9: 47-52.
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