Dr. Masoud Sadeghzadeh

Research Scientist
Nuclear Science and Technology Research Institute, Iran


Highest Degree
Ph.D. in Organic Chemistry from University of Tehran, Iran

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Biography

Dr. Masoud Sadeghzadeh obtained his PhD in Organic Chemistry in April 2013 at University of Tehran, Tehran, Iran. His field of interest related to Medicinal Chemistry, Organic Synthesis, Radiolabeling, Sigma Receptors, Green Chemistry, Radiopharmaceuticals Chemistry. Dr. Masoud Sadeghzadeh received honors include, First Ranking Student of Fundamental Science Department at University of Sistan and Baluchestan, Ranked 25th in the National Entrance Exam of Master of Science (among 8000 participants), and selected as an exceptional talent student by Sanjesh Organization of Iran. He is also invited as reviewer in scientific journals such as European Journal of Medicinal Chemistry, and Journal of Radioanalytical and Nuclear Chemistry. He has published 2 research papers in journals, 1 book chapter, and 8 abstracts in scientific meetings.

Area of Interest:

Chemistry
Medicinal Chemistry
Organic Synthesis
Green Chemistry
Pharmaceutical Chemistry

Selected Publications

  1. Sadeghzadeh, M., S. Shanehsazzadeh and A. Lahooti, 2015. Assessment of the effective absorbed dose of 4-benzyl-1-(3-[125I]-iodobenzylsulfonyl)piperidine in humans on the basis of biodistribution data of rats. Nucl. Med. Commun., 36: 90-94.
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  2. Sadeghzadeh, M., S. Sheibani, F.J. Daha and M. Erfani, 2014. Radioiodination of 4-benzyl-1-(3-iodobenzylsulfonyl)piperidine, 4-(3-iodobenzyl)-1-(benzylsulfonyl)piperazine and their derivatives via isotopic and non-isotopic exchange reactions. J. Radioanal. Nuc. Chem., 302: 1119-1125.
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  3. Sadeghzadeh, M., S. Sheibani, M. Ghandi, F.J. Daha, M. Amanlou, M. Arjmand and A.H. Bozcheloie, 2013. Synthesis and receptor binding studies of novel 4,4-disubstituted arylalkyl/arylalkylsulfonyl piperazine and piperidine-based derivatives as a new class of σ1 ligands. Eur. J. Med. Chem., 64: 488-497.
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  4. Sadeghzadeh, M., G.A. Charkhlooie and F.J. Daha, 2013. Synthesis, radiolabeling and biological evaluation of 99mTc-labeled deoxyglucose derivatives for molecular imaging. Iran. J. Pharm. Res., 12: 273-280.
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  5. Ghandi, M., S. Sheibani, M. Sadeghzadeh, F.J. Daha and M. Kubicki, 2013. Synthesis of novel tetra and pentacyclic benzosultam scaffolds via domino knoevenagel-hetero-diels-alder reactions in water. J. Iran. Chem. Soc., 10: 1057-1065.
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  6. Ghandi, M., M.A. Kia, M. Sadeghzadeh, A.H. Bozcheloei and M. Kubicki, 2013. Diastereoselective synthesis of novel pyrrolidine or pyrrolizine-fused Benzo-γ-Sultams via 1,3-Dipolar Cycloadditions. J. Heterocycl. Chem. 10.1002/jhet.2024.
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  7. Sadeghzadeh, M. and F. Johari Daha, 2011. Brain Tumors Diagnostic by Tumor Imaging Agents. In: In: Diagnostic Techniques and Surgical Management of Brain Tumors, Abujamra, A.L. (Ed.).Chapter 14, InTech Publisher, Rijeka, Croatia,ISBN: 978-953-307-589-1, pp: 275-286..

  8. Ghandi, M., S.H. Nazari, A.H. Bozcheloei and M. Sadeghzadeh, 2011. One-pot, three-component, synthesis of novel γ-sultam scaffolds via N-sulfonylation-intramolecular michael sequences. Tetrahedron Lett., 52: 6613-6615.

  9. Ghandi, M., E. Mohammadimehr, M. Sadeghzadeh and A.H. Bozcheloie, 2011. An efficient catalyst-free access to novel hexahydro-chromene and tetrahydro-pyrano[2,3-d]pyrimidine-annulated benzo-delta-sultones via new domino Knoevenagel-hetero-Diels-Alder reaction in water. Tetrahedron, 67: 8484-8491.

  10. Ghandi, M., A.H. Bozcheloei, S.H. Nazari and M. Sadeghzadeh, 2011. Solvent-dependent reactions for the synthesis of β-keto-benzo-γ-sultone scaffolds via DBU-catalyzed O-sulfonylation/intramolecular baylis-hillman/1,3-H shift or dehydration tandem sequences. J. Org. Chem., 76: 9975-9982.
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  11. Daha, F.J., K.H. Ebrahimabadi, M. Sadeghzadeh, G.A. Charkhlooie and M.R. Saidi, 2007. An improved synthesis and preliminary biodistribution study of a technetium-99m-labeled 2-amino-2-deoxy (thioacetyl)-D-glucose complex ([99mTc]-TA-DG) as a tumor imaging agent. Iran. J. Nucl. Med., 15: 43-48.
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