Dr. Othman El Mahdy Sayed Othman

Dr. Othman El Mahdy Sayed Othman

Professor
National Research Center, Egypt


Highest Degree
Ph.D. in Animal Genetics from Cairo University, Egypt

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Biography

Dr. Othman El Mahdy Sayed Othman is currently working as Professor at of Molecular Genetics and Animal Biotechnology, National Research Center, Dokki, Egypt. He has completed his Ph.D. in Animal Genetics from Cairo University, Egypt. His area of specialization includes Molecular Genetics and Animal Biotechnology. He also worked on 13 national and international research projects as principal investigator and member of research team. He successfully supervised 6 MSc and 2 PhD students. He is associate editor for Journal of Genetic Engineering and Biotechnology, American Journal of Biochemistry and Molecular Biology, Biotechnology, International Journal of Dairy Science, Trends in Molecular Sciences, Journal of Biological Sciences, and Journal of Animal and Veterinary Advance Research, Advances in Genetic Engineering and Biotechnology, and Journal of Molecular Biology and Genetic Engineering. He is also serving as member of Syndicate of Scientific Professions, Egyptian Society of Genetics, Egyptian German Society of Zoology, and Egyptian Society of Genetic Engineering & Biotechnology, and Arab Biologist Association, and American Association for the Advancement of Science. His area of research interest focuses on Genetic Polymorphism of QTL Genes in Farm Animals using different techniques; PCR, RFLP, SSCP and SNPs, Genetic diversity between different Breeds of Farm Animals using different techniques; MtDNA, Microsatellites and RAPD, Gene Mapping in different Farm Animals. He has published 58 research articles in journals contributed as author/co-author.

Area of Interest:

Animal and Veterinary Sciences
100%
Animal Biotechnology
62%
Animal Genetics
90%
Molecular Genetics
75%
Genetic Diversity
55%

Selected Publications

  1. Othman, O.E., M.G. Khodary, A.H. El-Deeb and H.A. Hussein, 2018. Five BoLA-DRB3 genotypes detected in Egyptian buffalo infected with foot and mouth disease virus serotype O. J. Genet. Eng. Biotechnol., 16: 513-518.
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  2. Othman, O.E., H.A.A. El-Kader, A.H.A. El-Rahim, O.M.A. El-Moneim and S.S. Alam, 2018. Genetic characterization of three fertility genes in Egyptian sheep and goat breeds. Indian J. Anim. Sci., 88: 200-205.

  3. Othman, O.E., A. Germot, M.G. Khodary, D. Petit and A. Maftah, 2018. Cytochrome b diversity and phylogeny of six Egyptian sheep breeds. Annu. Res. Rev. Biol., 22: 1-11.
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  4. Othman, O.E., A. Abou-Eisha, A.E. El-Din and N.A.A. El-Maaty, 2018. Genetic structure and ucleotide sequences of three productivity trait genes, in Egyptian buffalo. Annu. Res. Rev. Biol., 22: 1-8.
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  5. Othman, O.E., A. Abou-Eisha and A.E El-Din, 2018. Study on genetic polymorphism of IGFBP-3 gene in Egyptian Buffalo. Annu. Res. Rev. Biol., 29: 1-7.
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  6. Nagdy, H., K.G.M. Mahmoud, M.M.M. Kandiel, N.A. Helmy, S.S. Ibrahim, M.F. Nawito and O.E. Othman, 2018. PCR-RFLP of bone morphogenetic protein 15 (BMP15/FecX) gene as a candidate for prolificacy in sheep. Int. J. Vet. Sci. Med., 6: S68-S72.
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  7. Othman, O.E., K.F. Mahrous and H.I. Shafey, 2017. Mitochondrial DNA genetic variations among four horse populations in Egypt. J. Genet. Eng. Biotechnol., 15: 469-474.
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  8. Othman, O.E., H.A.M.A. El-Kader, S.S. Alam and S.H.A. El-Aziem, 2017. Cytochrome b conservation between six camel breeds reared in Egypt. J. Genet. Eng. Biotechnol., 15: 1-6.
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  9. Mahrous, K.F., H.I. Shafey, E.A. Balabel and O.E. Othman, 2017. Genetic biodiversity analysis of two mitochondrial genes in Arabian and thoroughbred horses. Biosci. Biotechnol. Res. Asia, 14: 25-32.
    CrossRef  |  Direct Link  |  

  10. Othman, O.E.M., N. Payet-Duprat, S. Harkat, A. Laoun, A. Maftah, M. Lafri and A. Da Silva, 2016. Sheep diversity of five Egyptian breeds: Genetic proximity revealed between desert breeds: Local sheep breeds diversity in Egypt. Small Rumin. Res., 144: 346-352.
    CrossRef  |  Direct Link  |  

  11. Othman, O.E., M.F. Abdel-Samad and N.A.A. El-Maaty, 2016. Evaluation of insulin-like growth factor-I gene polymorphism in Egyptian small ruminant breeds. Afr. J. Biotechnol., 15: 2714-2719.
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  12. Othman, O.E., H.R. Darwish, A. Abou-Eisha and A.E. El-Din, 2016. Investigation of calpastatin genetic polymorphism in egyptian sheep and goat breeds. Biosci. Biotech. Res. Asia, 13: 1879-1883.
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  13. Othman, O.E., E.A. Balabel and E.R. Mahfouz, 2016. Genetic characterization of myostatin and callipyge genes in Egyptian small ruminant breeds. Biotechnology, 15: 44-51.
    CrossRef  |  Direct Link  |  

  14. Othman, O.E., A.M. Nowier and M.E. El-Denary, 2016. Genetic variations in two casein genes among Maghrabi camels reared in Egypt. Biosci. Biotechnol. Res. Asia, 13: 473-480.
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  15. Othman, O.E. and E.R. Mahfouz, 2016. Genetic biodiversity, affinities and phylogeny of four goat breeds in Egypt. J. Biol. Sci., 16: 86-92.
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  16. Farag, I.M., A.M. Darwish, H.R. Darwish, K.B. AbdelAziz, W.A. Ramadan, M.I. Mohamed and O.E. Othman, 2016. Polymorphism of growth hormone gene and its association with wool traits in Egyptian sheep breeds. Afr. J. Biotechnol., 15: 549-556.
    CrossRef  |  

  17. Othman, O.E., S.S. Alam, H.A.A. El-Kader and O.M. Abd El Moneim, 2015. Genotyping of growth hormone gene in Egyptian small ruminant breeds. Biotechnology, 14: 136-141.
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  18. Othman, O.E., M.F. Abdel-Samad, N.A.A. El Maaty and K.M. Sewify, 2015. Genotyping and nucleotide sequences of growth hormone releasing hormone and its receptor genes in Egyptian buffalo. Br. Biotechnol. J., 5: 62-71.
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  19. Othman, O.E., L. Pariset, E.A. Balabel and M. Marioti, 2015. Genetic characterization of Egyptian and Italian sheep breeds using mitochondrial DNA. J. Genet. Eng. Biotechnol., 13: 79-86.
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  20. Othman, O.E., H.R. Darwish, A. Abou-Eisha, A.E. El-Din and M.F. Abdel-Samad, 2015. DNA characterization and polymorphism of KISS1 gene in Egyptian small ruminant breeds. Afr. J. Biotechnol., 14: 2335-2340.
    Direct Link  |  

  21. Othman, O.E., A.M. Nowier, H.A.A. El Kader, S.H.A. El Aziem and Y.M.K. Youssef, 2015. Genetic characterization of fibroblast growth factor-5 gene in rabbits. Global Veterinaria, 14: 453-458.

  22. Alam, S.S., H.A.A. El Kader, S.H.A. El Aziem and O.E. Othman, 2015. Genetic variation and SNP of tyrosinase gene among some camel breeds reared in Egypt. Biosci. Biotech. Res. Asia, 12: 23-28.

  23. Abdel-Aziem, S.H., H.A.M. Abdel Kader, S.S. Alam and O.E. Othman, 2015. Detection of MspI polymorphism and the single nucleotide polymorphism (SNP) of GH gene in camel breeds reared in Egypt. Afr. J. Biotechnol., 14: 752-757.
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  24. Othman, O.E., W.M. Ahmed, E.A. Balabel, M.M. Zaabal, H.H. El Khadrawy and E.M. Hanafi, 2014. Genetic polymorphism of CYP19 gene and its association with ovarian activity in Egyptian buffaloes. Global Veterinaria, 12: 768-773.

  25. Othman, O.E., S.S. Alam and S.H. Abd E-Azem, 2014. Single nucleotide polymorphism in Egyptian cattle insulin-like growthfactor binding protein-3 gene. J. Genet. Eng. Biotechnol., 12: 143-147.
    CrossRef  |  Direct Link  |  

  26. Othman, O.E., E.A. Balabel and M.F. Abdel-Samad, 2014. Mitochondrial DNA diversity in five Egyptian sheep breeds. Global Veterinaria, 12: 369-375.

  27. Othman, O.E., S.A. El-Fiky, N.A. Hassan, E.R. Mahfouz and E.A. Balabel, 2013. Genetic polymorphism detection of two α-Casein genes in three Egyptian sheep breeds. J. Genet. Eng. Biotechnol., 11: 129-134.
    CrossRef  |  Direct Link  |  

  28. Othman, O.E., M.F. Abdel-Samad, N.A.A.E. Maaty and K.M. Sewify, 2013. Genetic characterization of insulin growth factor-1 and its receptor genes in Egyptian buffalo (Bubalus bubalis L.). Br. Biotechnol. J., 3: 592-604.
    Direct Link  |  

  29. Othman, O.E. and M.F.Abdel-Samad, 2013. RFL polymorphism of three fertility genes in Egyptian buffalo. J. Appl. Biol. Sci., 7: 94-101.
    Direct Link  |  

  30. Othman, E.O., S.A. El-Fiky, N.A. Hassan, E.R. Mahfouz and E.A. Balabel, 2013. Genetic variations of β- and K-casein genes in Egyptian sheep breeds. J. Applied Biosci., 64: 4858-4866.
    Direct Link  |  

  31. Gabbianelli, F., L. Pariset, E.O. Othman, M. Mariotti, S. Ahmed, E.M. Balabel, and M. Gargani, 2013. Genetic characterization of sheep breeds of Egypt and Italy. Ital. J. Anim. Sci., .

  32. Othman, O.E., E.R. Mahfouz and S.M. El Nahas, 2012. Genetic variation among Northern and Southern Egyptian buffaloes using Polymerase Chain Reaction-Random Amplified Polymorphic DNA (PCR-RAPD). Afr. J. Biotechnol., 11: 12808-12813.
    Direct Link  |  

  33. Othman, E.O., F.A. Mohamed, A.A. Nadia and M.S. Karima, 2012. Evaluation of DNA polymorphism in Egyptian buffalo growth hormone and its receptor genes. J. Appl. Biol. Sci., 6: 37-42.
    Direct Link  |  

  34. Othman, E.O., A.E., Samia, A.H. Nagwa, R.M. Eman and A.B. Esraa, 2012. Genetic polymorphism of whey protein genes β-LG and α-LA in three Egyptian sheep breeds. J. Appl. Biol. Sci., 6: 25-30.
    Direct Link  |  

  35. Othman, E.O., 2012. Mitochondrial DNA as a marker for genetic diversity and evolution. Adv. Genet. Eng. Bioechnol., Vol. 1. .
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  36. Othman, O.E., F.A. Zayed, A.E. El-Gawead and M.R.A. El-Rahman, 2011. Genetic polymorphism of two genes associated with carcass trait in Egyptian buffaloes. J. Genet. Eng. Biotechnol., 9: 15-20.
    CrossRef  |  

  37. Othman, E.O., A.Z. Fawzia, A.E. Ali and R.A. Medhat, 2011. Genetic polymorphism of two carcass trait genes in egyptian buffaloes using PCR-RFLP. J. Genet. Eng. Biotechnol., 9: 15-20.

  38. Othman, E.O., A.Z. Fawzia, A.A.E. Gaweadand and T.R.A. El-Rahmana, 2011. Genetic Polymorphism of three genes associated with milk trait in Egyptian buffalo. J. Genet. Eng. Biotechnol., 9: 97-102.
    CrossRef  |  

  39. Othman, O.E. and S.S. Ahmed, 2010. Genetic polymorphism of BoLA-DRB3 exon 2 in Egyptian buffalo. Genes Genomes Genomics, 4: 70-73.
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  40. Ahmed, S.S. and O.E. Othman, 2009. Genotyping analysis of milk protein genes in different goat breeds reared in Egypt. J. Genet. Eng. Biotechnol., 7: 33-39.
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  41. Mahfouz, E.R., O.E. Othman, S.M. El-Nahas and M.A. El-Barody, 2008. Genetic variation between some Egyptian sheep breeds using RAPD-PCR. Res. J. Cell Mol. Biol., 2: 46-52.
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  42. El-Fiky, S.A., O.E. Othman, E.A. Balabel and S.A. Abd-Elbaset, 2008. The protective role of royal jelly against mutagenic effect of adriamycin and gamma radiation separately and in combination. Trends Applied Sci. Res., 3: 303-318.
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  43. Othman, O.E. and S.S. Ahmed, 2007. Genotyping of the caprine kappa-casein variants in Egyptian breeds. Int. J. Dairy Sci., 2: 90-94.
    CrossRef  |  Direct Link  |  

  44. Othman, O.E., 2006. Restriction fragment length polymorphism and gene mapping of two genes associated with composition in Egyption river buffalo. Int. J. Dairy Sci., 1: 84-92.
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  45. Othman, O.E. and S. Ahmed, 2006. Analysis of genetic polymorphisms in the Egyptian goats CSN1S2 using polymerase chain reaction. J. Boil. Sci., 6: 238-241.
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  46. Ahmed, S.S. and O.E. Othman, 2006. The characterization of HaeIII patterns in the second exon of the buffalo MHC class II DRB gene. Biotechnology, 5: 514-516.
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  47. Ahmed, S.S. and O.E. Othman, 2006. A PCR-RFLP method for the analysis of Egyptian goat MHC Class II DRB gene. Biotechnology, 5: 58-61.
    CrossRef  |  Direct Link  |  

  48. Othman, O.E., H.A.I. Ramadan, M.F.A. Samad, A.A. Abou-Mossalem, H.A. de Hondt and S.M. El-Nahas, 2005. Genetic diversity between different breeds of goat reared in Egypt using microsatellite analysis. J. Genet. Eng. Biotechnol., 3: 43-57.

  49. Othman, O.E., G.A. El-Rafey and T.A. Hassan, 2005. Cytogenetic and hematological effects of the antibiotic chloramphenicol on calves. Cytologia, 70: 87-92.
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  50. Othman, O.E., 2005. The identification of kappa-casein genotyping in Egyptian river buffalo using PDR-RFLP. Arab J. Biotech., 8: 265-274.
    Direct Link  |  

  51. Ahmed, S. and O.E. Othman, 2005. Detection of goat β-lactoglobulin genotypes using restriction fragment length polymorphism. J. Genet. Eng. Biotechnol., 3: 31-41.

  52. Abou-Mossalem, A.A., E.R., Mahfouz, O.E. Othman and S.M. El-Nahas, 2005. Analysis of genetic variations between goat breeds. J. Genet. Eng. Biotechnol., 3: 209-227.

  53. Othman, O.E., 2004. Chromosome and gene mapping homology between river buffalo, cattle and sheep using molecular markers. Biotechnology, 3: 119-125.
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  54. Othman, O.E. and S. Ahmed, 2004. Cytogenetic effects of the trypanocidal drug berenil in blood cultures of river buffalo. J. Biol. Sci., 4: 180-184.
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  55. Othman, E.O. and M.A. Bibars, 2004. Mapping of twelve bovine microsatellites on river buffalo chromosomes and homology with cattle chromosomes. Buffalo J., 2: 139-152.
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  56. Ahmed, S. and O.E. Othman, 2004. Cytogenetic studies on two drugs for natural relief of prostatic disorders. Cytologia, 69: 275-284.
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  57. Samad, A.M.F., O.E. Othman and H.A. Ramadan, 2003. Spontaneous frequency of sister chromatid exchanges in different breeds of goat reared in Egypt. Cytologia, 68: 153-157.
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  58. Othman, O.E., M. Aly, S. El-Nahas and H.M. Mohamed, 2003. Mutagenic potential of radio-frequency electromagnetic fields. Cytologia, 68: 35-43.
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  59. Othman, E.O., M.F. Abdel Samad and S.M. El Nahas, 2003. Synteny assignment of nine molecular markers to river buffalo chromosomes. Buffalo J., 3: 299-310.
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  60. Ahmed, S. and O.E. Othman, 2003. Clastogenic effects of the fasciolicide drug fasinex on river buffalo lymphocyte cultures in vitro. Mutat. Res., 541: 115-121.
    CrossRef  |  

  61. Othman, O.E., M.S. Aly and S.M. El-Nahas, 2001. Aneuploidy in workers occupationally exposed to electromagnetic field detected by FISH. Cytologia, 66: 117-125.
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  62. Ramadan, H.A.I., O.E. Othman, M.F.A. Samad, A.A. Abou-Mossallem and S.M. El Nahas, 2000. Somatic cell hybrids characterization by monoclonal antibodies and assignment of CD71 to the q arm of buffalo and cattle chromosome one. J. Egypt German. Soc. Zool., 31C: 133-143.
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  63. Othman, O.E.M.S., 2000. Cytogenetic effect of the anticancer drug epirubicin on Chinese hamster cell line in vitro. Mutat. Res., 468: 109-115.
    CrossRef  |  

  64. Othman, O.E., 2000. Mutagenic effect of two antineoplastic agents separately and in combination. Egypt. J. Genet. Cytol., 29: 25-38.

  65. Othman, O.E. and M.F. Abdel Samad, 2000. Genotoxic effect of diazinon in culture of Chinese hamster cell line wg3h. Egypt. J. Genet. Cytol., 29: 25-38.

  66. Hondt, H.A., O.E. de, M.F. Othman, A.A. Abdel Samad, H.A. Hassan, S.M. Oraby and S.M. El Nahas, 2000. Omatic cell hybrids characterization by monoclonal antibodies and assignment of CD71 to the Q arm of buffalo and cattle chromosome one. J. Egypt German Soc. Zool., 31C: 133-143.

  67. De Hondt, H.A., O.E. de, M.F. Othman, A.A. Abdel Samad, H.A. Hassan, S.M. Oraby and S.M. El Nahas, 2000. Mapping of eight molecular markers to river buffalo chromosomes and the confirmation of the nature of chromosomes 2 and 3. J. Egypt German Soc. Zool., 31: 39-48.

  68. Othman, O.E. and S.M. El Nahas, 1999. Synteny Assignment of four genes and two microsatellite markers in river buffalo (Bubalus bubalis L.). J. Anim. Breed. Genet., 116: 161-168.
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  69. Aly, M.S., O.E. Othman and S.M. El-Nahas, 1999. Specific numerical chromosomal aberrations induced by adriamycin. Environ. Mol. Mutag., 33: 161-166.
    PubMed  |  Direct Link  |  

  70. El-Nahas, S.M., H.O. Oraby, O.E. Othman, H.A. Hondt, A.A. de Bosma and J.E. Womack, 1997. Use of molecular markers for the identification of river buffalo chromosomes: Chromosome one. J. Anim. Breed. Genet., 114: 451-455.
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  71. De Hondt, H.A., D. Gallagher, H. Oraby, O.E. Othman and A.A. Bosma et al., 1997. Gene mapping in river buffalo (Bubalus bubalis L.): Five syntenic groups. J. Anim. Breed. Genet., 114: 79-85.
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  72. Nahas, S.M., H.A. Hondt, O.S. Othman, A.A. Bosma and N.A. Haan, 1993. Assignment of genes to chromosome 4 of the river buffalo with a panel of buffalo-hamster cells. J. Anim. Breed. Genet., 110: 182-185.
    CrossRef  |  PubMed  |  

  73. El-Nahas, S.M., H.A. Hondt, O.S. de Othman, A.A. Bosma and N.A. de Haan, 1993. Assignment of genes to chromosome 4 of the rive buffalo with a panel of buffalo-hamster hybrid cells. J. Anim. Breed. Genet., 110: 182-185.
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