Dr. Ayman Moawad Mahmoud
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Dr. Ayman Moawad Mahmoud

Associate Professor in Molecular & Cell Physiology
Beni-Suef University, Egypt


Highest Degree
Ph.D. in Physiology from Beni-Suef University, Egypt

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Area of Interest:

Biomedical Sciences
100%
Oxidative Stress
62%
Obesity
90%
Cardiovascular Diseases
75%
Diabetes
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
153
Abstracts
0

Selected Publications

  1. Ranneh, Y., A.M. Akim, H.A. Hamid, H. Khazaai, A. Fadel and A.M. Mahmoud, 2019. Stingless bee honey protects against lipopolysaccharide induced-chronic subclinical systemic inflammation and oxidative stress by modulating Nrf2, NF-κB and p38 MAPK. Nutr. Metab., Vol. 16. 10.1186/s12986-019-0341-z.
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  2. Mohamed, H.M. and A.M. Mahmoud, 2019. Chronic exposure to the opioid tramadol induces oxidative damage, inflammation and apoptosis and alters cerebral monoamine neurotransmitters in rats. Biomed. Pharmacother., 110: 239-247.
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  3. Mahmoud, A.M., W.G. Hozayen, I.H. Hasan, E. Shaban and M. Bin-Jumah, 2019. Umbelliferone ameliorates CCl4-induced liver fibrosis in rats by upregulating PPARγ and attenuating oxidative stress, inflammation and TGF-β1/Smad3 signaling. Inflammation, (In Press). 10.1007/s10753-019-00973-8.
    CrossRef  |  Direct Link  |  
  4. Mahmoud, A.M., R.J.H. Bautista, M.A. Sandhu and O.E. Hussein, 2019. Beneficial effects of citrus flavonoids on cardiovascular and metabolic health. Oxid. Med. Cell. Longevity, Vol. 2019. 10.1155/2019/5484138.
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  5. Hozayen, W.G., A.M. Mahmoud, E.M. Desouky, E.S. El-Nahass, H.A. Soliman and A.A. Farghali, 2019. Cardiac and pulmonary toxicity of mesoporous silica nanoparticles is associated with excessive ROS production and redox imbalance in Wistar rats. Biomed. Pharmacother., 109: 2527-2538.
    CrossRef  |  PubMed  |  Direct Link  |  
  6. Bautista, R.J.H., A.M. Mahmoud, M. Konigsberg and N.E.L.D. Guerrero, 2019. Obesity: Pathophysiology, monosodium glutamate-induced model and anti-obesity medicinal plants. Biomed. Pharmacother., 111: 503-516.
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  7. Althunibat, O.Y., A.M. Al Hroob, M.H. Abukhalil, M.O. Germoush, M. Bin-Jumah and A.M. Mahmoud, 2019. Fisetin ameliorates oxidative stress, inflammation and apoptosis in diabetic cardiomyopathy. Life Sci., 221: 83-92.
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  8. Allam, A.A., S.I. Othman and A.M. Mahmoud, 2019. Deleterious effects of perinatal exposure to potassium bromate on the development of offspring of Swiss mice. Toxicol. Ind. Health, 35: 63-78.
    CrossRef  |  Direct Link  |  
  9. AlHaithloul, H.A., M.F. Alotaibi, M. Bin-Jumah, H. Elgebaly and A.M. Mahmoud, 2019. Olea europaea leaf extract up-regulates Nrf2/ARE/HO-1 signaling and attenuates cyclophosphamide-induced oxidative stress, inflammation and apoptosis in rat kidney. Biomed. Pharmacother., 111: 676-685.
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  10. Al Hroob, A.M., M.H. Abukhalil, O.E. Hussein and A.M. Mahmoud, 2019. Pathophysiological mechanisms of diabetic cardiomyopathy and the therapeutic potential of epigallocatechin-3-gallate. Biomed. Pharmacother., 109: 2155-2172.
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  11. Mahmoud, A.M., M.O. Germoush, K.M. Al-Anazi, A.H. Mahmoud, M.A. Farah and A.A. Allam, 2018. Commiphora molmol protects against methotrexate-induced nephrotoxicity by up-regulating Nrf2/ARE/HO-1 signaling. Biomed. Pharmacother., 106: 499-509.
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  12. Jimenez, R., M. Toral, M. Gomez-Guzman, M. Romero, M. Sanchez, A.M. Mahmoud and J. Duarte, 2018. The role of Nrf2 signaling in PPARβ/δ-mediated vascular protection against hyperglycemia-induced oxidative stress. Oxid. Med. Cell. Longevity, Vol. 2018. 10.1155/2018/5852706.
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  13. Germoush, M.O., S.I. Othman, M.A. Al-Qaraawi, H.M. Al-Harbi and O.E. Hussein et al., 2018. Umbelliferone prevents oxidative stress, inflammation and hematological alterations and modulates glutamate-nitric oxide-cGMP signaling in hyperammonemic rats. Biomed. Pharmacother., 102: 392-402.
    CrossRef  |  Direct Link  |  
  14. Fadel, A., J. Ashworth, A. Plunkett, A.M. Mahmoud, Y. Ranneh and W. Li, 2018. Improving the extractability of arabinoxylans and the molecular weight of wheat endosperm using extrusion processing. J. Cereal Sci., 84: 55-61.
    CrossRef  |  Direct Link  |  
  15. Fadel, A., A.M. Mahmoud, J.J. Ashworth, W. Li, Y.L. Ng and A. Plunkett, 2018. Health-related effects and improving extractability of cereal arabinoxylans. Int. J. Biol. Macromol., 109: 819-831.
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  16. Fadel, A., A. Plunkett, J. Ashworth, A.M. Mahmoud, Y. Ranneh, M. El Mohtadi and W. Li, 2018. The effect of extrusion screw-speed on the water extractability and molecular weight distribution of arabinoxylans from defatted rice bran. J. Food Sci. Technol., 55: 1201-1206.
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  17. Elgebaly, H.A., N.M. Mosa, M. Allach, K.F. El-Massry, A.H. El-Ghorab, A.M. Al Hroob and A.M. Mahmoud, 2018. Olive oil and leaf extract prevent fluoxetine-induced hepatotoxicity by attenuating oxidative stress, inflammation and apoptosis. Biomed. Pharmacother., 98: 446-453.
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  18. Al-Rasheed, N.M., N.M. Al-Rasheed, Y.A. Bassiouni, I.H. Hasan, M.A. Al-Amin, H.N. Al-Ajmi and A.M. Mahmoud, 2018. Simvastatin ameliorates diabetic nephropathy by attenuating oxidative stress and apoptosis in a rat model of streptozotocin-induced type 1 diabetes. Biomed. Pharmacother., 105: 290-298.
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  19. Al-Otaibi, F.S., J.S. Ajarem, M.A. Abdel-Maksoud, S. Maodaa, A.A. Allam, G.I. Al-Basher and A.M. Mahmoud, 2018. Stone quarrying induces organ dysfunction and oxidative stress in Meriones libycus. Toxicol. Ind. Health, 34: 679-692.
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  20. Al-Basher, G.I., H. Aljabal, R.S. Almeer, A.A. Allam and A.M. Mahmoud, 2018. Perinatal exposure to energy drink induces oxidative damage in the liver, kidney and brain and behavioral alterations in mice offspring. Biomed. Pharmacother., 102: 798-811.
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  21. Al Hroob, A.M., M.H. Abukhalil, R.D. Alghonmeen and A.M. Mahmoud, 2018. Ginger alleviates hyperglycemia-induced oxidative stress, inflammation and apoptosis and protects rats against diabetic nephropathy. Biomed. Pharmacother., 106: 381-389.
    CrossRef  |  Direct Link  |  
  22. Ahmed, O., H. Fahim, A. Mahmoud and E. Ahmed, 2018. Bee venom and hesperidin effectively mitigate complete Freund’s adjuvant-induced arthritis via immunomodulation and enhancement of antioxidant defense system. Arch. Rheumatol., 33: 198-212.
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  23. Satta, S., A.M. Mahmoud, F.L. Wilkinson, M.Y. Alexander and S.J. White, 2017. The role of Nrf2 in cardiovascular function and disease. Oxid. Med. Cell. Longevity, Vol. 2017. 10.1155/2017/9237263.
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  24. Sarem, Z., C. Bumke-Vogt, A.M. Mahmoud, B. Assefa and M.O. Weickert et al., 2017. Glucagon decreases IGF-1 bioactivity in humans, independently of insulin, by modulating its binding proteins. J. Clin. Endocrinol. Metab., 102: 3480-3490.
    CrossRef  |  Direct Link  |  
  25. Mahmoud, A.M., W.G. Hozayen and S.M. Ramadan, 2017. Berberine ameliorates methotrexate-induced liver injury by activating Nrf2/HO-1 pathway and PPARγ and suppressing oxidative stress and apoptosis in rats. Biomed. Pharmacother., 94: 280-291.
    CrossRef  |  Direct Link  |  
  26. Mahmoud, A.M., S.M. Abd El-Twab and E.S. Abdel-Reheim, 2017. Consumption of polyphenol-rich Morus alba leaves extract attenuates early diabetic retinopathy: The underlying mechanism. Eur. J. Nutr., 56: 1671-1684.
    CrossRef  |  Direct Link  |  
  27. Mahmoud, A.M., S. Alqahtani, S.I. Othman, M.O. Germoush and O.E. Hussein et al., 2017. Commiphora molmol modulates glutamate-nitric oxide-cGMP and Nrf2/ARE/HO-1 pathways and attenuates oxidative stress and hematological alterations in hyperammonemic rats. Oxid. Med. Cell. Longevity, Vol. 2017. 10.1155/2017/7369671.
    CrossRef  |  Direct Link  |  
  28. Mahmoud, A.M., O.E. Hussein, W.G. Hozayen and S.M. Abd El-Twab, 2017. Methotrexate hepatotoxicity is associated with oxidative stress, and down-regulation of PPARγ and Nrf2: Protective effect of 18β-glycyrrhetinic acid. Chemico-Biol. Interact., 270: 59-72.
    CrossRef  |  Direct Link  |  
  29. Mahmoud, A.M., M.Y. Alexander, Y. Tutar, F.L. Wilkinson and A. Venditti, 2017. Oxidative stress in metabolic disorders and drug-induced injury: The potential role of Nrf2 and PPARs activators. Oxid. Med. Cell. Longevity, Vol. 2017. 10.1155/2017/2508909.
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  30. Mahmoud, A.M., M.O. Germoush, M.F. Alotaibi and O.E. Hussein, 2017. Possible involvement of Nrf2 and PPARγ up-regulation in the protective effect of umbelliferone against cyclophosphamide-induced hepatotoxicity. Biomed. Pharmacother., 86: 297-306.
    CrossRef  |  Direct Link  |  
  31. Mahmoud, A.M., M.M. Abdel-Rahman, N.A. Bastawy and H.M. Eissa, 2017. Modulatory effect of berberine on adipose tissue PPARγ, adipocytokines and oxidative stress in high fat diet/streptozotocin-induced diabetic rats. J. Applied Pharmaceut. Sci., 7: 1-10.
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  32. Mahmoud, A.M., H.M. Mohammed, S.M. Khadrawy and S.R. Galaly, 2017. Hesperidin protects against chemically induced hepatocarcinogenesis via modulation of Nrf2/ARE/HO-1, PPARγ and TGF-β1/Smad3 signaling and amelioration of oxidative stress and inflammation. Chemico-Biol. Interact., 277: 146-158.
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  33. Mahmoud, A.M., F.L. Wilkinson, E.M. McCarthy, D. Moreno-Martinez and A. Langford-Smith et al., 2017. Endothelial microparticles prevent lipid-induced endothelial damage via Akt/eNOS signaling and reduced oxidative stress. FASEB J., 31: 4636-4648.
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  34. Mahmoud, A.M., F.L. Wilkinson, A.M. Jones, J.A. Wilkinson, M. Romero, J. Duarte and M.Y. Alexander, 2017. A novel role for small molecule glycomimetics in the protection against lipid-induced endothelial dysfunction: Involvement of Akt/eNOS and Nrf2/ARE signaling. Biochim. Biophys. Acta (BBA)-Gen. Subj., 1861: 3311-3322.
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  35. Mahmoud, A.M., A.R. Zaki, M.E. Hassan and G. Mostafa-Hedeab, 2017. Commiphora molmol resin attenuates diethylnitrosamine/phenobarbital-induced hepatocarcinogenesis by modulating oxidative stress, inflammation, angiogenesis and Nrf2/ARE/HO-1 signaling. Chemico-Biol. Interact., 270: 41-50.
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  36. Mahmoud, A.M., 2017. Exercise amaliorates metabolic disturbances and oxidative stress in diabetic cardiomyopathy: Possible underlying mechanisms. Adv. Exp. Med. Biol., 999: 207-230.
    CrossRef  |  PubMed  |  Direct Link  |  
  37. Mahmoud, A.M. and S.M. Abd El-Twab, 2017. Caffeic acid phenethyl ester protects the brain against hexavalent chromium toxicity by enhancing endogenous antioxidants and modulating the JAK/STAT signaling pathway. Biomed. Pharmacother., 91: 303-311.
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  38. Hozayen, W.G., S.M. Ramadan, A. Fadel and A.M. Mahmoud, 2017. Berberine mitigates methotrexate-induced oxidative stress and inflammation in the cerebrum of rats. J. Applied Pharmaceut. Sci., 7: 43-49.
    CrossRef  |  Direct Link  |  
  39. Hamed, A.I., R.B. Said, A.S. Al-Ayed, J. Moldoch and U.A. Mahalel et al., 2017. Fingerprinting of strong spermatogenesis steroidal saponins in male flowers of Phoenix dactylifera (date palm) by LC-ESI-MS. Nat. Prod. Res., 31: 2024-2031.
    CrossRef  |  Direct Link  |  
  40. Assefa, B., A.M. Mahmoud, A.F. Pfeiffer, A.L. Birkenfeld, J. Spranger and A.M. Arafat, 2017. Insulin-like Growth Factor (IGF) binding protein-2, independently of IGF-1, induces GLUT-4 translocation and glucose uptake in 3T3-L1 adipocytes. Oxid. Med. Cell. Longevity, Vol. 2017. 10.1155/2017/3035184.
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  41. Aly, M.S., S.R. Galaly, N. Moustafa, H.M. Mohammed, S.M. Khadrawy and A.M. Mahmoud, 2017. Hesperidin protects against diethylnitrosamine/carbon tetrachloride-induced renal repercussions via up-regulation of Nrf2/HO-1 signaling and attenuation of oxidative stress. J. Applied Pharmaceut. Sci., 7: 7-14.
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  42. Al-Rasheed, N.M., N.M. Al-Rasheed, I.H. Hasan, M.A. Al-Amin, H.N. Al-Ajmi, R.A. Mohamad and A.M. Mahmoud, 2017. Simvastatin ameliorates diabetic cardiomyopathy by attenuating oxidative stress and inflammation in rats. J. Oxid. Med. Cell. Longevity. .
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  43. Al-Basher, G., J.S. Ajarem, A.A. Allam and A.M. Mahmoud, 2017. Green tea protects against perinatal nicotine-induced histological, biochemical and hematological alterations in mice offspring. Int. J. Pharmacol., 13: 109-121.
    CrossRef  |  Direct Link  |  
  44. Ajarem, J.S., G. Al-Basher, A.A. Allam and A.M. Mahmoud, 2017. Camellia sinensis prevents perinatal nicotine-induced neurobehavioral alterations, tissue injury and oxidative stress in male and female mice newborns. Oxid. Med. Cell. Longevity. 10.1155/2017/5985219.
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  45. Abdel-Rahman, M.M., A.M. Mahmoud, N.A. Bastawy and H.M. Eisa, 2017. Anti-hyperlipidemic and myocardial enhancing effects of berberine in high fat diet/streptozotocin-induced diabetic rats; possible role of adiponectin. Nutr. Food Sci. Int. J., Vol. 2. 10.19080/NFSIJ.2017.02.555580.
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  46. Mahmoud, A.M., H.A. Soliman, A.M. Abd El-Hameed and E.S. Abd El-Rehim, 2016. Wheat germ oil attenuates cyclophosphamide-induced testicular injury in rats. World J. Pharm. Pharmaceut. Sci., 5: 40-52.
    Direct Link  |  
  47. Mahmoud, A.M., 2016. Protective effects of umbelliferone in experimental testicular ischaemia/reperfusion injury in rats. Anat. Physiol., Vol. 6. 10.4172/2161-0940.1000189.
    CrossRef  |  Direct Link  |  
  48. Mahmoud, A.M. and O.E. Hussein, 2016. Hesperidin as a promising anti-diabetic flavonoid: the underlying molecular mechanism. Int. J. Food Nutr. Sci., 3: 313-314.
    Direct Link  |  
  49. Mahmoud, A.M. and O.E. Hussein, 2016. Flavonoids as potential Wnt/β-catenin signaling modulators for colorectal cancer prevention. Int. J. Food Nutr. Sci., 3: 210-212.
    Direct Link  |  
  50. Mahmoud, A.M. and O.E. Hussein, 2016. Anti-diabetic effect of Naringin: Insights into the molecular mechanism. Diabetes Obes Int. J., Vol. 1. .
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  51. Kamel, E.M., A.M. Mahmoud, S.A. Ahmed and A.M. Lamsabhi, 2016. A phytochemical and computational study on flavonoids isolated from Trifolium resupinatum L. and their novel hepatoprotective activity. Food Funct., 7: 2094-2106.
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  52. Hussein, O.E., M.O. Germoush and A.M. Mahmoud, 2016. Ruta graveolens protects against isoniazid/rifampicin-induced nephrotoxicity through modulation of oxidative stress and inflammation. Global J. Biotechnol. Biomater. Sci., 2: 8-13.
    Direct Link  |  
  53. Hozayen, W.G., A.M. Mahmoud, H.A. Soliman and S.R. Mostafa, 2016. Spirulina versicolor improves insulin sensitivity and attenuates hyperglycemia-mediated oxidative stress in fructose-fed rats. J. Intercult. Ethnopharmacol., 5: 57-64.
    CrossRef  |  PubMed  |  Direct Link  |  
  54. Alqahtani, S. and A.M. Mahmoud, 2016. Gamma-glutamylcysteine ethyl ester protects against cyclophosphamide-induced liver injury and hematologic alterations via upregulation of pparγ and attenuation of oxidative stress, inflammation and apoptosis. Oxid. Med. Cell. Longevity, Vol. 2016. 10.1155/2016/4016209.
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  55. Al-Samhari, M.M., N.M. Al-Rasheed, S. Al-Rejaie, N.M. Al-Rasheed, I.H. Hasan, A.M. Mahmoud and N. Dzimiri, 2016. Possible involvement of the JAK/STAT signaling pathway in N-acetylcysteine-mediated antidepressant-like effects. Exp. Biol. Med., 241: 509-518.
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  56. Al-Rasheed, N.M., N.M. Al-Rasheed, I.H. Hasan, M.A. Al-Amin, H.N. Al-Ajmi and A.M. Mahmoud, 2016. Sitagliptin attenuates cardiomyopathy by modulating the JAK/STAT signaling pathway in experimental diabetic rats. Drug Des. Dev. Ther., 10: 2095-2107.
    CrossRef  |  Direct Link  |  
  57. Ahmed, O.M., A.M. Mahmoud, S.F.A. Zid and N.Y. Saber, 2016. Silymarin and hydroethanolic extracts of Silybum marianum leaves and fruits attenuate diethylnitrosamine/phenobarbital-induced nephrotoxicity via their antioxidant and anti-inflammatory actions. Am. J. Biochem., 6: 21-29.
    CrossRef  |  Direct Link  |  
  58. Abdella, E.M., A.M. Mahmoud and A.M. El-Derby, 2016. Brown seaweeds protect against azoxymethane-induced hepatic repercussions through up-regulation of peroxisome proliferator-activated receptor gamma and attenuation of oxidative stress. Pharmaceut. Biol., 54: 2496-2504.
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  59. Abdel-Rahman, M.M., A.M. Mahmoud, N.M. Mostafa, M.E. Saleh and H.M. Eissa, 2016. Sildenafil reduces ischemia/reperfusion testicular injury after torsion/detorsion in rats. J. Applied Pharmaceut. Sci., 6: 135-140.
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  60. Abd El-Twab, S.M., W.G. Hozayen, O.E. Hussein and A.M. Mahmoud, 2016. 18β-Glycyrrhetinic acid protects against methotrexate-induced kidney injury by up-regulating the Nrf2/ARE/HO-1 pathway and endogenous antioxidants. Renal Failure, 38: 1516-1527.
    CrossRef  |  Direct Link  |  
  61. Abd El-Twab, S.M., H.M. Mohamed and A.M. Mahmoud, 2016. Taurine and pioglitazone attenuate diabetes-induced testicular damage by abrogation of oxidative stress and up-regulation of the pituitary-gonadal axis. Can. J. Physiol. Pharmacol., 94: 651-661.
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  62. Abd El-Reheem, E.S., A.M. Mahmoud, A.M. Abd El-Hameed and H.A. Soliman, 2016. Effect of cinnamaldehyde on the toxicity of cyclophosphamide in the testes of rats: Influence of pre- and post-treatment schedule. Nat. Sci., 14: 44-51.
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  63. Toral, M., M. Romero, R. Jimenez, A.M. Mahmoud and E. Barroso et al., 2015. Carnitine palmitoyltransferase-1 up-regulation by PPAR-β/δ prevents lipid-induced endothelial dysfunction. Clin. Sci., 129: 823-837.
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  64. Soliman, H.A., W.G. Hozayen, A.M. Mahmoud, N.A. Fayed and M.A. Abo-Seif, 2015. Significance of the hepatitis C virus core antigen testing as an alternate marker for hepatitis diagnosis in Egyptian patients. Eur. Rev. Med. Pharmacol. Sci., 19: 2240-2245.
  65. Mahmoud, A.M., W.G. Hozayen, H.A. Soliman and S.R. Mostafa, 2015. Enteromorpha flexuosa improves insulin sensitivity and metabolic control in fructose-induced diabetic rats. J. Endocrinol. Diabetes Obes., Vol. 3, No. 2. .
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  66. Mahmoud, A.M., R.R. Ahmed, H.A. Soliman and M. Salah, 2015. Ruta graveolens and its active constituent rutin protect against diethylnitrosamine-induced nephrotoxicity through modulation of oxidative stress. J. Applied Pharmaceut. Sci., 5: 16-21.
    CrossRef  |  Direct Link  |  
  67. Mahmoud, A.M., O.M. Ahmed, M.B. Ashour and A. Abdel-Moneim, 2015. In vivo and in vitro antidiabetic effects of citrus flavonoids; a study on the mechanism of action. Int. J. Diabetes Dev. Countries, 35: 250-263.
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  68. Mahmoud, A.M., O.M. Ahmed, M.B. Ashour and A. Abdel-Moneim, 2015. In vivo and in vitro antidiabetic effects of citrus flavonoids; a study on the mechanism of action. Int. J. Diabetes Dev. Countries, (In Press). 10.1007/s13410-014-0268-x.
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  69. Mahmoud, A.M., E.M. Abdella, A.M. El-Derby and E.M. Abdella, 2015. Protective effects of Turbinaria ornata and Padina pavonia against azoxymethane-induced colon carcinogenesis through modulation of PPAR gamma, NF-κB and oxidative stress. Phytother. Res., 29: 737-748.
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  70. Mahmoud, A.M., E.M. Abdella, A.M. El‐Derby and E.M. Abdella, 2015. Protective effects of Turbinaria ornata and Padina pavonia against azoxymethane-induced colon carcinogenesis through modulation of PPAR gamma, NF-κB and oxidative stress. Phytother. Res., (In Press). 10.1002/ptr.5310.
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  71. Mahmoud, A.M., B.M. Morsy, D.S. Abdel-Hady and R.M. Samy, 2015. Prunus armeniaca leaves extract protects against isoniazid and rifampicin induced nephrotoxicity through modulation of oxidative stress and inflammation. Int. J. Food Nutr. Sci., 2: 100-105.
    CrossRef  |  Direct Link  |  
  72. Mahmoud, A.M., 2015. Flavonoids as ligands for peroxisome proliferator-activated receptor γ. Int. J. Food Nutr. Sci., 2: 98-99.
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  73. Mahmoud, A.M. and H.S. Al Dera, 2015. 18β-Glycyrrhetinic acid exerts protective effects against cyclophosphamide-induced hepatotoxicity: Potential role of PPARγ and Nrf2 upregulation. Genes Nutr., Vol. 10. 10.1007/s12263-015-0491-1.
    CrossRef  |  Direct Link  |  
  74. Germoush, M.O., H.A. Elgebaly, S. Hassan and A.M. Mahmoud, 2015. Anti-diabetic effects of Padina pavonia in fructose-induced diabetic rats. Aljouf Univ. Sci. Eng. J., 2: 10-16.
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  75. Al-Rasheed, N.M., M.M. Al-Oteibi, R.Z. Al-Manee, S.A. Al-Shareef and N.M. Al-Rasheed et al., 2015. Simvastatin prevents isoproterenol-induced cardiac hypertrophy through modulation of the JAK/STAT pathway. Drug Des. Dev. Ther., 9: 3217-3229.
    CrossRef  |  PubMed  |  Direct Link  |  
  76. Ahmed, R.R., A.M. Mahmoud, M.B. Ashour and A.M. Kamel, 2015. Hesperidin protects against diethylnitrosamine-induced nephrotoxicity through modulation of oxidative stress and inflammation. Natl. J. Physiol. Pharm. Pharmacol., 5: 391-397.
    CrossRef  |  Direct Link  |  
  77. Ahmed, R.R., A. Mahmoud, O.M. Ahmed, A. Metwalli and H. Ebaid, 2015. Up-regulation of Hsp72 and keratin16 mediates wound healing in streptozotocin diabetic rats. Biol. Res., Vol. 48. 10.1186/s40659-015-0044-5.
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  78. Soliman, A.S., A.M. Mahmoud, Z. Serry and F. Dawood, 2014. Therapeutic effects of low-level laser and reflexology on adhesive capsulitis in elderly type 2 diabetic patients. Asian J. Pharmaceut. Clin. Res., 7: 317-321.
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  79. Osman, A.A., A.M. Mahmoud and A.S. Soliman, 2014. Rapid detection of bovine-specific nucleic acid sequences in cow milk using polymerase chain reaction. Int. J. Nutr. Food Sci., 3: 141-144.
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  80. Morsy, B.M., A.M. Mahmoud, M.I. Zanaty, A. Abdel-Moneim and M.A. Abo-Seif, 2014. Beneficial effects of milk kefir in patients with chronic hepatitis C virus infection. Int. J. Bioassays, 3: 3086-3091.
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  81. Mahmoud, A.M., O.M. Ahmed and S.R. Galaly, 2014. Thymoquinone and curcumin attenuate gentamicin-induced renal oxidative stress, inflammation and apoptosis in rats. EXCLI J., 13: 98-110.
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  82. Mahmoud, A.M., M.O. Germoush, H.A. Elgebaly, K.N.M. Elsayed, S. Hassan, N.M. Mousa and O.E. Hussein, 2014. Anti-diabetic and insulin sensitizing effects of Padina pavonia and Turbenaria ornata in streptozotocin/nicotinamide diabetic rats. Asian J. Pharmaceut. Clin. Res., 7: 74-78.
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  83. Mahmoud, A.M., M.O. Germoush and A.S. Soliman, 2014. Berberine attenuates isoniazid-induced hepatotoxicity by modulating peroxisome proliferator-activated receptor γ, oxidative stress and inflammation. Int. J. Pharmacol., 10: 451-460.
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  84. Mahmoud, A.M., M.O. Germoush and A.S. Soliman, 2014. Ruta graveolens mitigates ammonium chloride-induced hyperammonemia by modulating antioxidant status and pro-inflammatory cytokines. Life Sci. J., 11: 269-275.
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  85. Mahmoud, A.M., M. Toral, M. Romero, M. Gomez-Guzman and M. Sanchez et al., 2014. Protective effects of Peroxisome Proliferator-Activated Receptor (PPAR)-β activation on lipid-induced endothelial dysfunction via carnitine palmitoyl transferase-1 upregulation. Heart, Vol. 100. 10.1136/heartjnl-2014-306916.26.
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  86. Mahmoud, A.M., A. El-Derby, K.N. Elsayed and E. Abdella, 2014. Brown seaweeds ameliorate renal alterations in mice treated with the carcinogen azoxymethane. Int. J. Pharm. Pharmaceut. Sci., 6: 365-369.
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  87. Mahmoud, A.M., 2014. Hesperidin protects against cyclophosphamide-induced hepatotoxicity by upregulation of PPARγ and abrogation of oxidative stress and inflammation. Can. J. Physiol. Pharmacol., 92: 717-724.
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  88. Germoush, M.O. and A.M. Mahmoud, 2014. Berberine mitigates cyclophosphamide-induced hepatotoxicity by modulating antioxidant status and inflammatory cytokines. J. Cancer Res. Clin. Oncol., 140: 1103-1109.
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  89. Galaly, S.R., O.M. Ahmed and A.M. Mahmoud, 2014. Thymoquinone and curcumin prevent gentamicin-induced liver injury by attenuating oxidative stress, inflammation and apoptosis. J. Physiol. Pharmacol., 65: 823-832.
    PubMed  |  Direct Link  |  
  90. Ahmed, O.M., B.M. Ashour, H.E. Fahim, A.M. Mahmoud and N.A. Ahmed, 2014. Preventive effect of Spirulina versicolor and Enteromorpha flexuosa ethanolic extracts against diethylnitrosamine/benzo(a)pyrene-induced hapatocarcinogencity in rats. J. Int. Acad. Res. Multidisciplin., 2: 633-650.
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  91. Abouzid, S.F., O.M. Ahmed, R.R. Ahmed, A.M. Mahmoud, E. Abdella and M.B. Ashour, 2014. Antihyperglycemic effect of crude extracts of some Egyptian plants and algae. J. Med. Food, 17: 400-406.
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  92. Mahmoud, A.M., O.M. Ahmed, A. Abdel-Moneim and M.B. Ashour, 2013. Upregulation of pparγ mediates the antidiabetic effects of citrus flavonoids in type 2 diabetic rats. Int. J. Bioassays, 2: 756-761.
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  93. Mahmoud, A.M., O.E. Hussein and S.A. Ramadan, 2013. Amelioration of cyclophosphamide-induced hepatotoxicity by the brown seaweed Turbenaria ornata. Studies, 1: 9-17.
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  94. Mahmoud, A.M., 2013. Hematological alterations in diabetic rats: Role of adipocytokines and effect of citrus flavonoids. EXCLI J., 12: 647-657.
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  95. Mahmoud, A.M. and A.S. Soliman, 2013. Rutin attenuates hyperlipidemia and cardiac oxidative stress in diabetic rats. Egypt. J. Med. Sci., 34: 287-302.
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  96. Ebaid, H., O.M. Ahmed, A.M. Mahmoud and R.R. Ahmed, 2013. Limiting prolonged inflammation during proliferation and remodeling phases of wound healing in streptozotocin-induced diabetic rats supplemented with camel undenatured whey protein. BMC Immunol., Vol. 14. 10.1186/1471-2172-14-31.
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  97. Abou Riag, N.B.S., A.M. Mahmoud and S.A. Ramadan, 2013. Sildenafil alleviates insulin sensitivity via attenuating oxidative stress and proinflammatory cytokines in diabetic rats. Int. J. Pharm. Bio. Sci., 4: 427-436.
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  98. Abdella, E.M., R.R. Ahmed, M.B. Ashour, O.M. Ahmed, S.F. Abu Zid and A.M. Mahmoud, 2013. Bioinformatics analysis of functional genes and proteins for the diagnosis of obesity-induced type 2 diabetes. Int. J. Fundamental Applied Sci., 2: 23-28.
  99. Abdel-Moneim, A., B.M. Morsy, A.M. Mahmoud, M.A. Abousief and M. Zanaty, 2013. Benificial therapeutic effects of Nigella sativa and Ginger officinalle in HCV patients in Egypt. EXCLI J., 12: 943-955.
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  100. Mahmoud, A.M., O.M. Ahmed, M.B. Ashour and A. Abdel-Moneim, 2012. Hesperidin and naringin attenuate hyperglycemia-mediated oxidative stress and proinflammatory cytokine production in high fat fed/strptozotocin-induced type 2 diabetic rats. Diabetes Complications, 26: 483-490.
  101. Mahmoud, A.M., 2012. Influence of rutin on biochemical alterations in hyperammonemia in rats. Exp. Toxicol. Pathol., 64: 783-789.
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  102. Ahmed, O.M., A.M. Mahmoud, A. Abdel-Moneim and M.B. Ashour, 2012. Antidiabetic effects of hesperidin and naringin in type 2 diabetic rats. Diabetologia Croatica, 41: 53-67.
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  103. Ahmed, O.M., A. Afifi, T.M. Ali, S.A. Ramadan and A.M. Mahmoud, 2012. Ameliorative effects of sildenafil in acetic acid-induced chronic colitis in rats. Life Sci. J., 9: 354-361.
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  104. Ahmed, O.M., A.M. Mahmoud, A. Abdel-Moneim and M.B. Ashour, 2011. Antihyperglycemic and antihyperlipidemic effects of hesperidin and naringin in high fat diet/streptozotocin type 2 diabetic rats. Life Sci., 8: 91-101.
  105. Abdel-Moneim, A., M.B. Ashour, A.M. Mahmoud and O.M. Ahmed, 2011. Insulin sensitizing effects of hesperidin and naringin in experimental model of induced type 2 diabetes in rats: Focus on tumor necrosis factor-alpha and Resistin. Nat. Sci., 9: 134-141.
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  106. Ahmed, O.M., A.A. Moneim, I.A. Yazid and A.M. Mahmoud, 2010. Antihyperglycemic, antihyperlipidemic and antioxidant effects and the probable mechanisms of action of Ruta graveolens and rutin in Nicotinamide/streptozotocin diabetic albino rats. Diabetol. Croatica, 39: 15-35.
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