Dr. Mohammad Saleh Al-Haggar

Dr. Mohammad Saleh Al-Haggar

Professor
Mansoura University, Egypt


Highest Degree
M.D. in Pediatrics and Genetics from Mansoura University, Egypt

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Biography

Dr. Mohammad Saleh Al-Haggar is currently working as Professor of Pediatrics and Neurogenetics, Mansoura University, Egypt. He obtained his M.D. in Pediatrics and Genetics from same University in 1995. His area of expertise includes Versatile in Human Genetics, Pediatric Hematology, Medical Biostatistics and wide range of Computer Skills; Data Presentation and Management. He is having expended experience in the field of Family Genetics, seven years experience of the medical work in Saudi culture on private basis led almost 15 years in the field of Pediatric Hematology especially those with Genetic basis; implemented many research projects and finalized many talented publications in peer-reviewed journals. He worked as General Practitioner in the Armed Forces Hospitals, Clinical Research Fellow at Central National Research of Italy, Resident of Paediatrics, Clinical Demonstrator, Assistant Lecturer, Lecturer, and Assistant Professor of Pediatrics at Mansoura University, Egypt. He has published 40 articles in journals contributed as author/co-author. He is also serving as reviewer in number of national and international journals, and member of editor board in many journals. Dr. Mohammad Saleh received honors includes Winner of Doctors 14th Anniversary Medal, Egyptian Doctors Syndicate, Winner of Mansoura Medical Prize, Winner of Professor Dr Mohammad Fakhry Meckawy prize in Pedicatrics for 2011. He is also working as member of European Society for Pediatric Research, Egyptian Pediatric Society, Egyptian Association of Genetics, and Egyptian Society for Genetics, Egyptian Journal of Hematology, and Egyptian Journal of Pediatric Neurology, and member of organizing Committee for the Annual Meeting of Pediatrics Department, Faculty of Medicine, Mansoura University.

Area of Interest:

Biomedical Sciences
100%
Human Genetics
62%
Pediatric Hematology
90%
Medical Biostatistics
75%
Data Presentation and Management
55%

Selected Publications

  1. Zedan, M., A. Bakr, B. Shouman, H. Zaghloul and M. Al-Haggar, 2014. Single nucleotide polymorphism of IL4C-590T and IL4RA 175V and immunological parameters in Egyptian asthmatics with different clinical phenotypes. J. Allergy Ther., Vol. 5. 10.4172/2155-6121.1000189.
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  2. El-Sayyad, H.I., M.M. Al-Haggar, H.A. El-Ghawet and I.H. Bakr, 2014. Effect of maternal diabetes and hypercholesterolemia on fetal liver of albino Wistar rats. Nutrition, 30: 326-336.
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  3. Bakr, A., M. Al-Haggar, R. Eid, Y. Wahba and P. Coucke et al., 2014. Focal segmental glomerulosclerosis in a child with marfan syndrome and novel fibrillin gene mutation. Pediatr. Nephrol., 29: 1825-1825.
  4. Al-Haggar, M.S., S. Yahia, D. Abdel-Hady, A. Al-Saied, R. Al-Kenawy and R. Abo-El-Kasem, 2014. Phenotype-genotype updates from familial Mediterranean fever database registry of Mansoura University Children' Hospital, Mansoura, Egypt. Indian J. Hum. Genet., 20: 43-50.
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  5. Al-Haggar, M., C.R. Largiader, D. Abdel-Hady, T. Barakat, J.M. Nuoffer and A.A. Al-Refaei, 2014. Partial expression of ornithine transcarbamylase deficiency in an Egyptian female carrier. Int. J. Gynaecol. Obstetr., 124: 174-175.
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  6. Al-Haggar, M., 2014. SNPs as co-morbid factors for drug abuse and ischemic heart disease. Gene Technol., Vol. 3. 10.4172/2329-6682.1000107.
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  7. Al‐Haggar, M., N. Salem, Y. Wahba, N. Ahmad and L. Jonard et al., 2014. Novel homozygous SLC29A3 mutations among two unrelated Egyptian families with spectral features of H‐syndrome. Pediatr. Diabetes, (In Press). 10.1111/pedi.12160.
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  8. Al-Haggar, M.M.S., B.A. Khair-Allaha, M.M. Islam and S.A. Mohamed, 2013. Bioinformatics in high throughput sequencing: Application in evolving genetic diseases. J. Data Mining Genomics Proteomics, Vol. 4. 0.4172/2153-0602.1000131.
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  9. Al-Haggar, M., N. Ahmad, S. Yahia, A. Shams and B. Hasaneen et al., 2013. Sporadic fibrodysplasia ossificans progressiva in an Egyptian infant with c.617G > A mutation in ACVR1 gene: A case report and review of literature. Case Rep. Genet., 10.1155/2013/834605.
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  10. Al-Haggar, M., A. Taranta, P. Bencivenga, N. Ahmad, H.A. Hadid and Y. Wahba, 2013. Recent experience in an Egyptian medical center: Strategies for the clinical and genetic diagnoses of nephropathic cystinosis. Br. J. Med. Med. Res., 3: 1918-1928.
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  11. Al-Haggar, M., A. Shams, A. Madej-Pilarczyk, T. Barakat and M. Puzianowska-Kuznicka, 2013. Ultrastrutural skin changes in Egyptian mandibuloacral dysplasia patients with p.Arg527Leu LMNA mutation and in their asymptomatic heterozygotic mothers. J. Clin. Pathol., 66: 1000-1004.
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  12. Al-Haggar, M., 2013. Evolving molecular methods for detection of mutations. Gene Technol., Vol. 2. 10.4172/2329-6682.1000e104.
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  13. Al-Haggar, M., 2013. Cystinosis as a lysosomal storage disease with multiple mutant alleles: Phenotypic-genotypic correlations. World J. Nephrol., 2: 94-102.
    PubMed  |  
  14. El-Sayyad, H.I., M.S. Al-Haggar, H.A. El-Ghawet and I.H. Bakr, 2012. Cardiomyopathy and angiogenesis defects of Wistar rat fetuses of diabetic and hypercholesterolemic mothers. Nutrition, 28: e33-e43.
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  15. Al-Tonbary, Y., M. Al-Haggar, O. Salama, M. Abul-Kheir, A. El-Alfy and M. Hafez, 2012. Platelet count and serum thrombopoietin level as predictors for morbidity and/or mortality in thrombocytopenic neonates. Hematology, 17: 341-345.
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  16. Al-Haggar, M., O. Sakamoto, A. Shaltout, A. Al-Hawari, Y. Wahba and D. Abdel-Hadi, 2012. Mutation analysis of the GLUT2 gene in three unrelated Egyptian families with Fanconi-Bickel syndrome: Revisited gene atlas for renumbering. Clin. Exp. Nephrol., 16: 604-610.
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  17. Al-Haggar, M., A. Taranta, A. El-Hawary, A. Al-Said, A.A. Shaban and Y. Wahba, 2012. Novel truncating mutation in the CTNS gene in an Egyptian family with cases of infantile nephropathic cystinosis and congenital heart malformations. Middle East J. Med. Genet., 1: 71-75.
  18. Al-Haggar, M., A. Madej-Pilarczyk, L. Kozlowski, J.M. Bujnicki and S. Yahia et al., 2012. A novel homozygous p.Arg527Leu LMNA mutation in two unrelated Egyptian families causes overlapping mandibuloacral dysplasia and progeria syndrome. Eur. J. Hum. Genet., 20: 1134-1140.
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  19. Al-Haggar, M., 2012. Fanconi-Bickel syndrome as an example of marked allelic heterogeneity. World J. Nephrol., 1: 63-68.
    PubMed  |  
  20. Al-Haggar, M., S. Yahia, K. Damjanovich, N. Ahmad, I. Hamada and P. Bayrak-Toydemir, 2011. p. R672C mutation of MYH3 gene in an Egyptian infant presented with Freeman-Sheldon syndrome. Indian J. Pediatr., 78: 103-105.
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  21. Al-Haggar, M., O. Sakamoto, A. Shaltout, A. El-Hawary, Y. Wahba and D. Abdel-Hadi, 2011. Fanconi Bickel syndrome: Novel mutations in GLUT 2 gene causing a distinguished form of renal tubular acidosis in two unrelated Egyptian families. Case Rep. Nephrol. 10.1155/2011/754369.
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  22. Al-Haggar, M., S. Yahia, D. Abdel-Hadi, F. Grill and A. Al Kaissi, 2010. Sirenomelia (symelia apus) with Potteri's syndrome in connection with gestational diabetes mellitus: A case report and literature review. Afr. Health Sci., 10: 395-399.
  23. Nezar, M., A. Abd El-Baky, O. Soliman, A. Hammad and M. Al-Haggar, 2009. Endothelin-1 and leptin as markers of intrauterine growth restriction. Indian J. Pediatr., 76: 485-488.
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  24. Al-Tonbary, Y., M. Al-Haggar, R. EL-Ashry, S. EL-Dakroory, H. Azzam and A. Fouda, 2009. Vitamin E and N-acetylcysteine as antioxidant adjuvant therapy in children with acute lymphoblastic leukemia. Adv. Hematol., 10.1155/2009/689639.
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  25. Al-Haggar, M., A. Bakr, T. Tajima, K. Fujieda and A. Hammad et al., 2009. Familial hypomagnesemia with hypercalciuria and nephrocalcinosis: unusual clinical associations and novel claudin16 mutation in an Egyptian family. Clin. Exp. Nephrol., 13: 288-294.
    CrossRef  |  
  26. Al-Haggar, M., Z. Al-Morsy, S. Yahia, N. Chalaby, A. Ragab and A. Mesbah, 2008. Correlation of thyroid and growth hormones to chromosomal instability in egyptian fanconi anemia patients. Ind. J. Pediatr., 75: 679-684.
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  27. Settin, A., M. Al-Haggar, T. El-Dosokey, R. Al-Baz and N. Abdelrazik et al., 2007. Prognostic cytogenetic markers in childhood acute lymphoblastic leukemias, Cases from Mansoura, Egypt. Hematology, 12: 103-111.
    CrossRef  |  
  28. Settin, A., M. Al-Haggar, T. Al-Dosoky, R. Al-Baz, N. Abdelrazik, M. Fouda, S. Aref and Y. Al-Tonbary, 2007. Prognostic cytogenetic markers in childhood acute lymphoblastic leukemia. Indian J. Pediatr., 74: 255-263.
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  29. Abdel-Razik, N., M. Al-Haggar, H. Al-Marsafawy, H. Abdel-Hadi and R. Al-Baz, 2007. Impact of long-term iron supplementation in breast-fed infants. Ind. J. Pediatr., 74: 739-745.
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  30. Settin, A.A., M.S. Al-Haggar, H. El Marsafawy, A.A. Alkader and R.A. El Baz et al., 2006. Genetic analysis of rheumatic fever among Egyptian families: Consanguinity pattern, segregation analysis and blood group association. J. Medical Sci., 6: 359-366.
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  31. Settin, A., T. Al-Dosokey, M. Al-Haggar, M. El-Bendary and M. Ezz et al., 2006. C282Y and H63D haemochromatosis alleles in Egyptian patients with cirrhosis. Arab J. Gastroenterol., 7: 59-63.
  32. Settin, A., T. Al-Dosokey, M. Al-Haggar, M. Al-Bendary and M. Ezz et al., 2006. Increased risk of liver cirrhosis among Egyptian carriers of S and/or Z mutant alleles of Alpha1 anti-trypsin gene. Arab J. Gastroenterol., 7: 14-18.
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  33. Settin, A., M. Al-Haggar, T. El-Dosokey, R. Al-Baz and N. Abdelrazik et al., 2006. Prognostic cytogenetic markers in childhood acute lymphoblastic leukemias, Cases from Mansoura, Egypt. Haematology, 11: 341-349.
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  34. Settin, A., M. Al-Haggar, R. Al-Baz, H. Yousof and N. Osman, 2006. Screening for G6PD mediterranean mutation among Egyptian neonates with high or prolonged jaundice. Haema, 9: 83-90.
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  35. Settin, A., M. Al-Haggar, M. Neamatallah, A. Al- Said and M. Hafez, 2006. Detection of beta-thalassemia mutations using primer-specific amplification compared to reversed dot blot hybridization technique in egyptian cases. Haema, 9: 401-409.
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  36. Settin, A., M. Al-Haggar, M. Gouida, R. Al-Baz and R. Abu Alkasem et al., 2006. Diagnostic significance of flow cytometric analysis of dna ploidy and apoptosis in children with lymphadenopathy. Haema, 9: 240-246.
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  37. Al-Haggar, M.S., A.A. Settin, M. Ragab, M. Al-Shahat and H. Abdel-Hadi et al., 2006. Segregation analysis of p53, c-myc and DNA ploidy using flow cytometry among Egyptian families with childhood leukemia. J. Medical Sci., 6: 906-914.
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  38. Al-Haggar, M., Z. Al-Naggar and M. Abdel-Salam, 2006. Biofeedback and cognitive behavioral therapy for Egyptian adolescents suffering from chronic fatigue syndrome. J. Pediatr. Neurol., 4: 161-169.
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  39. Al-Haggar, M., R. El-Baz, H. Youseff, N. Othman and R. Ali, 2006. Overview on attention deficit hyperactivity disorder among children from Delta regions of Egypt (A 10 years-study). J. Pediatric Neurol., 4: 15-18.
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  40. Al-Haggar, M., N. Yahia and H. Ghanem, 2006. High dairy calcium intake in pubertal girls: Relation to weight gain and bone mineral status. J. Medical Sci., 6: 631-635.
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  41. Al-Haggar, M., M. Ragab, M. Awad and R. Al-Baz, 2006. Soluble adhesion molecules in juvenile idiopathic arthritis: Relation to activity and clinical subtype. J. Med. Sci., 6: 474-479.
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  42. Al-Haggar, M., M. Al-Aiouty, M. Ragab and S. Yehia, 2006. Neurophysiologic evaluation of peripheral nerve function in uremic egyptian children. J. Pediat. Neurol., 4: 89-95.
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  43. Al-Haggar, M., H. Al-Marsafawy, N. Abdel-Razek, R. Al-Baz and A.H. Mostafa, 2006. Acute painful crises of sickle cell disease in Egyptian children: Predictors of severity for a preventive strategy. Int. J. Hematol., 83: 224-228.
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  44. Settin, A., M. Al-Haggar, R. Al-Baz, M. Al-Aiouty and M. Hafez, 2005. Screening of mentally handicapped Egyptian children for fragile X Syndrome using clinical, cytogenetic and molecular approaches. J. Pediatr. Neurol., 3: 217-225.
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  45. Al-Haggar, M., A. Settin, M. Gouida, R. Al-Baz and R. Abu Alkasem et al., 2005. Case report: Early diagnosis of Hodgkin`s disease based on Flow Cytometry parameters. Br. Med. J. Middle East, 12: 14-15.
  46. Abdalla, A., H. Al-Marsafawy, M.M. Abou El-Khair, M.E. El-Regal and M.M. Al-Haggar, 2004. Hepatopulmonary syndrome in children with cirrhosis: Echocardiographic findings. Benha Med. J., 21: 515-516.
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  47. Abdallah, A.F., A.M. Bakr, M. El-Haggar and T. Amer, 1999. Renal hemodynamic changes in children with liver cirrhosis. Pediatr. Nephrol., 13: 854-858.
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