Mr. Erhirhie  Earnest Oghenesuvwe

Mr. Erhirhie Earnest Oghenesuvwe

Chukwuemeka Odumegwu Ojukwu University, Igbariam, Nigeria

Highest Degree
Ph.D. in Pharmacology and Toxicology from Nnamdi Azikiwe University Awka, Nigeria

Share this Profile

Area of Interest:

Pharmacology and Toxicology
Pharmaceutical Sciences
Medicinal Plants

Selected Publications

  1. Ihekwereme, C., P. Agafuchukwu and E. Erhirhie, 2020. Artesunate antagonizes antiplasmodial activity of Vernonia amygdalina methanol leaf extract in murine model of malaria. Am J. Physiol. Biochem. Pharmacol., 10.5455/ajpbp.20190822021151.
    CrossRef  |  Direct Link  |  
  2. Erhirhie, E.O., and E.E. Ilodigwe, 2019. Sub-chronic toxicity evaluation of Dryopteris filix-mas (L.) schott, leaf extract in albino rats. Braz. J. Pharm. Sci., 10.1590/s2175-97902019000118107.
    CrossRef  |  Direct Link  |  
  3. Ngwoke, K.G., A.G. Akwagbulam, E.O. Erhirhie, D.L. Ajaghaku, F.B.C. Okoye and C.O. Esimone, 2018. Antioxidant, anti-inflammatory, analgesic properties, and phytochemical characterization of stem bark extract and fractions of Anthocleista nobilis. Pharmacogn. Res., 10: 81-87.
    Direct Link  |  
  4. Erhirhie, E.O., J.O.T. Emudainohwo, S.O. Igboeme, D.L. Ajaghaku, N.T. Ujam, M.U. Okezie and E.E. Ilodigwe, 2018. Preclinical screening techniques for antidiarrheal drugs: A review. Am. J. Physiol. Biochem. Pharmacol., 7: 61-74.
    CrossRef  |  
  5. Erhirhie, E.O., E.E. Ilodigwe and C.P. Ihekwereme, 2018. Ficus sycomorus L (Moraceae): A review on its phytopharmacology and toxicity profile. Discov. Phytomed., 5: 64-71.
    Direct Link  |  
  6. Erhirhie, E.O., C.P. Ihekwereme and E.E. Ilodigwe, 2018. Advances in acute toxicity testing: strengths, weaknesses and regulatory acceptance. Interdiscip. Toxicol., 11: 5-12.
    Direct Link  |  
  7. Erhirhie, E.O. and E.E. Ilodigwe, 2018. Toxicological evaluation of Dryopteris filix-mas (L.) Schott, leaf extract in albino rats. Braz. J. Pharm. Sci. (In Press). .
  8. Erhirhie E.O., O.N. Ezemokwe and E.E. Ilodigwe, 2018. Teratogenic effects of ethanol leaf extract of Dryopteris filix-mas (L.) Schott. Alger. J. Natural Prod., 6: 573-583.
    Direct Link  |  
  9. Ojezele, M.O., E.O. Erhirhie and O.E. Adedapo, 2017. Comparative in-vivo antimicrobial activities of aqueous and methanol leaf extracts of Viscum album from Kola nitida and Theobromae cacao and their effects on intestinal flora on healthy experimental rats. Nig. J. Pharm. Sci., 16: 31-40.
  10. Ogenevwaire, F.O., E.E. Ilodigwe, J.M. Okonta, E.O. Erhirhie and D.L. Ajaghaku, 2017. Inhibition of the acetylcholine and histamine receptors may be the possible mechanisms of antiulcer effect of Solenostemon monostachyus P. Beauv. (Lamiaceae). Int. J. Res. Pharm. Biosci., 4: 17-22.
    Direct Link  |  
  11. Tedwins, E.J.O., O.U.U. Benjamin, E.D. Ayobola, M.E. Goodies and E.E. Oghenesuvwe, 2016. A comparative study on the effect of Massularia acuminate and mouthwash against isolates from the oral cavity. J. Restorative Dent., 4: 64-68.
    CrossRef  |  Direct Link  |  
  12. Ojezele, M.O., E.O. Erhirhie and O.A. Arojojoye, 2016. Effects of Viscum album (mistletoe) from three host plants (cocoa, kola and coffee) on semen quality of Wistar albino rats. Chem. Int., 2: 14-18.
    Direct Link  |  
  13. Ihekwereme, P.C., E.O. Erhirhie, I.S. Mbagwu, E.E. Ilodigwe, D.L. Ajaghaku and F.B. Okoye, 2016. Antidiarrheal property of Napoleona imperialis may be due to Procyanidins and Ellagic acid derivatives. J. Applied Pharm. Sci., 6: 101-106.
    Direct Link  |  
  14. Ihekwereme, C.P., C.M. Aniezue, E.O. Erhirhie and U.G. Okafor, 2016. Preliminary evaluation of the anti-emetic activity of crude methanol extract and fractions of Ocimum gratissimum. J. Dev. Drugs, Vol. 5. 10.4172/2329-6631.1000149.
    CrossRef  |  Direct Link  |  
  15. Erhirhie, E.O., 2016. Antimalarial therapies and infertility: A comprehensive review. Toxicol. Int., 23: 107-111.
    CrossRef  |  Direct Link  |  
  16. Adaeze, D.C., I.E. Emeka, O.J. Mathew, E.E. Oghenesuvwe and A. Amara, 2016. Safety profile and antioxidant activity of the ethanol leaf extract and fractions of Spondias mombin Linn, Family Anarcadiacae. J. Int. Res. Med. Pharm. Sci., 8: 145-157.
  17. Oghenesuvwe, E.E., I.E. Emeka, A.D. Lotanna, M.I. Sonne and M.E. Goodies, 2015. Toxicity evaluation of a commercial herbal preparation commonly used in Nigeria. Eur. J. Med. Plants, 5: 176-190.
    Direct Link  |  
  18. Oghenesuvwe, E.E., B.A. Benneth, M.G. Emuesiri, C. Paul and A.O. Innocent, 2015. Ethno-pharmacological review of Buchhoizia coriacea (Wonderful Kola). Int. J. Adv. Pharm. Biol. Chem., 4: 149-155.
    Direct Link  |  
  19. Moke, E.G., E.O. Erhirhie and E. Ahante, 2015. The effect of anaesthetic agents (chloroform and diethylether) on fasting blood glucose and heamatological parameters. Sky J. Biochem., 4: 10-12.
  20. Moke, E.G., E.E. Ilodigwe, J.M. Okonta, J.O.T. Emudainohwo and D.L. Ajaghaku et al., 2015. Antidiabetic activity and toxicity evaluation of aqueous extracts of Spondias mombin and Costus afer on wistar rats. Br. J. Pharm. Res., 6: 333-342.
  21. Goodies, M.E., I.E. Emmanuel and E.O. Earnest, 2015. Evaluation of the ulcerogenic potential of the aqueous extract of Spondias mombin and Custus afer. Int. J. Adv. Pharm. Biol. Chem., 4: 282-286.
  22. Erhirhie, E.O., M.E. Goodies and C. Paul, 2015. Cissampelos owariensis: Experimental review. Pharm. Innov. J., 3: 75-77.
  23. Emudainohwo, J.O.T., G.E. Moke, D.E. Ejebe and E.O. Erhirhie, 2015. An investigation of the anti-diarrhoel effect of aqueous and ethanol stem bark extract of Alchornea cordifolia in Wistar rats. J. Pharmacogn. Phytochem., 4: 183-187.
  24. Emudainohwo, J.O.T., E.O. Erhirhie, E.G. Moke and E.K. Emmanuel, 2015. A comprehensive review on ethno-medicine, phytochemistry and ethnopharmacology of Chrysophyllum albidum. J. Adv. Med. Pharm. Sci., 3: 147-154.
  25. Emudainohwo, J.O.T., E.O. Erhirhie, E.G. Moke and D.E. Ejebe, 2015. Hypoglycemic effect of ethanol leaf extract of Thuamatococus daneilli (Eletd). in alloxan induced diabetic wistar rats. IOSR J. Pharm. Biol. Sci., 10: 59-64.
  26. Emudainohwo, J.O.T., E.O. Erhirhie and E.G. Moke, 2015. Anti-diarrheal activity of the aqueous leaf extract of Ageratum conyzoides in wistar rats. J. Applied Sci. Environ. Manage., 19: 169-175.
    Direct Link  |  
  27. Emudainohwo, J.O.T., E.G. Moke and O.E. Erhirhie, 2015. Effect of aqueous extract of unripe seeds of Carica papaya on four hematological parameters of Salmonella-induce enteric fever in wistar rats. J. Adv. Med. Pharm. Sci., 4: 1-9.
  28. Emudainohwo, J.O.T., D.E. Ejebe, E.O. Erhirhie and E.G. Moke, 2015. Investigation into the aphrodisiac properties of aqueous and ethanol root extracts of Manniophyton fulvum in male Wistar rats. IOSR J. Pharm. Biol. Sci., 10: 1-6.
    Direct Link  |  
  29. Umeh, V.N., E.E. Ilodigwe, D.L. Ajaghaku, E.O. Erhirhie, G.E. Moke and P.A. Akah, 2014. Wound-healing activity of the aqueous leaf extract and fractions of Ficus exasperate (Moraceae) and its safety evaluation on albino rats. J. Tradit. Complement. Med., 4: 246-252.
    CrossRef  |  Direct Link  |  
  30. Erhirhie, E.O., N.E. Ekene and D.L. Ajaghaku, 2014. Guidelines on dosage calculation and stock solution preparation in experimental animals' studies. J. Nat. Sci. Res., 4: 100-106.
  31. Erhirhie, E.O. and G.E. Moke, 2014. Xylopia aethiopica: A review of its ethnomedicinal, chemical and pharmacological properties. Am. J. PharmTech Res., 4: 22-37.
  32. Erhirhie, E.O. and E.N. Ekene, 2014. Hepatoprotective effects of Capsicum frutescence supplemented diet against Acetaminophene induced liver damage in Wistar rats. Nig. J. Sci. Environ., 13: 108-114.
  33. Ekene, E.N. and E.O. Erhirhie, 2014. Garcinia kola: A review of its ethnomedicinal, chemical and pharmacological properties. Int. J. Curr. Res. Rev., 6: 1-7.
  34. Erhirhie, E.O., L.O. Ewhre, F.R. Ilevbare and D.E. Okparume, 2013. The roles of Capsicum in diabetes mellitus. Continental J. Pharmacol. Toxicol. Res., 6: 22-27.
  35. Erhirhie, E.O., J.O.T. Emudainohwo and E.U. Edafe, 2013. Effect of Vernonia amygdalina and Ocimum gratissimum combined leaves extract on blood glucose and biochemical parameters in alloxan induced diabetic rats. Continental J. Pharmacol. Toxicol. Res., 6: 13-21.
  36. Erhirhie, E.O. and N.E. Ekene, 2013. Medicinal values on Citrullus lanatus (Watermelon): Pharmacological review. Int. J. Res. Pharm. Biomed. Sci., 4: 1305-1312.
    Direct Link  |  
  37. Ekene, E.N. and E.O. Erhirhie, 2013. Effects of Capsicum frutescence supplemented diet on lipid profile of Wistar rats. Nig. J. Sci. Environ., 12: 57-61.