Dr. Damian Chukwu Odimegwu

Dr. Damian Chukwu Odimegwu

Senior Lecturer
University of Nigeria, Nsukka, Nigeria


Highest Degree
Ph.D. in Natural Sciences from Ruhr University Bochum, Germany

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Area of Interest:

Biomedical Sciences
100%
Biotechnology
62%
Molecular Virology
90%
Pharmacy
75%
Viral Infections
55%

Selected Publications

  1. Onah, I.A., E.B. Onuigbo and D.C. Odimegwu, 2019. Adjuvant effect of Vernonia amygdalina leaf extract on host immune response to hepatitis b virus subunit vaccine. Pharmazie, 74: 179-185.
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  2. Ibe, M.I., D.C. Odimegwu and E.B. Onuigbo, 2019. Alginate-coated chitosan microparticles encapsulating an oral plasmid-cured live Salmonella enteric serovar Gallinarum vaccine cause a higher expression of interferon-gamma in chickens compared to the parenteral live vaccine. Avian Pathol. 10.1080/03079457.2019.1616673.
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  3. Onah, I.A., E.B. Onuigbo, M.I. Ngwu and D.C. Odimegwu, 2018. Suppressive effect of Garcinia kola on the humoral immune response of mice to hepatitis B virus subunit vaccine. Int. J. Trop. Dis. Health, 30: 1-13.
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  4. Onah, I.A., C. Ofojebe and D.C. Odimegwu, 2018. Evaluation of Vigna subterranean seed extract as possible adjuvant for Typhoid fever vaccine. J. Adv. Med. Pharm. Sci., 16: 1-8.
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  5. Odimegwu, D.C., I.A. Onah, C. Ife, C.E. Odoh and G.I. Onukwube, 2018. Antibody response to respiratory syncytial virus antigen is modulated by artesunate. Clin. Biotechnol. Microbiol., 2: 364-370.

  6. Odimegwu, D.C., F.B.C. Okoye, S.C. Nworu and C.C. Esimone, 2018. Anti-respiratory syncytial virus activities of leaf extracts of Alchornea cordifolia and Alchornea floribunda. Afr. J. Pharm. Pharmacol., 12: 97-105.

  7. Odimegwu, D.C., 2018. Low-dose Sekikaic acid modulates host immunity and protects cells from respiratory syncytial virus infection. Biotechnol. J. Int., 21: 1-10.
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  8. Odimegwu, D.C. and C.O. Esimone, 2018. In vitro antiviral activity of Nauclea latifolia root bark extract against the respiratory syncytial virus. Eur. J. Med. Plants, 22: 1-7.
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  9. Ibezim, E.C., M.A. Momoh, V.I. Onyishi, I. Nwabunike, D.C. Odimegwu, N.E. Ibezim and N.J. Nzekwe, 2018. Evaluating the ethyl-acetate fraction of crude methanol leaf extract of Ocimum gratissimum formulated as ointments for wound healing properties using the excision wound model. J. Pharm. Allied Sci., Vol. 15. .
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  10. Ezeilo, M.C., G.A. Engwa, R.I. Iroha and D.C. Odimegwu, 2018. Seroprevalence and associated risk factors of hepatitis B virus infection among children in Enugu metropolis. Virol.: Res. Treat., Vol. 9. 10.1177/1178122X18792859.
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  11. Ezeilo, M.C., G.A. Engwa, R.I. Iroha and D.C. Odimegwu, 2018. High anti-HCV seroprevalence and low performance of ICT strip in diagnosing hepatitis C virus infection in children in Enugu metropolis a preliminary study. Open Virol. J., 12: 149-156.

  12. Onah, I.A., G.I. Onukwube, C.E. Odoh and D.C. Odimegwu, 2017. Moring oleifera, an adjuvant for respiratory syncytial virus vaccine. Aust. J. Basic Applied Sci., 11: 95-101.

  13. Agbo, M.O., D.C. Odimegwu, F.B.C. Okoye and P.O. Osadebe, 2017. Antiviral activity of Salidroside from the leaves of Nigerian mistletoe (Loranthus micranthus Linn) parasitic on Hevea brasiliensis against respiratory syncytial virus. Pak. J. Pharm. Sci., 30: 1251-1256.

  14. Uzor, P.F., D.C. Odimegwu, W. Ebrahim, P.O. Osadebe and N.J. Nwodo et al., 2016. Anti-respiratory syncytial virus compounds from two endophytic fungi isolated from Nigerian medicinal plants. Drug Res., 66: 527-531.
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  15. Okoye, F.B., D.C. Odimegwu, C.S. Nworu, M.O. Agbo, C.O. Esimone, P.O. Osadebe and P. Proksch, 2016. Modulation of intracellular expression of ifn╬│ and IL-2 in culture of splenic T lymphocytes by some flavonoid glycosides of Alchornea floribunda. Pharm. Biol., 54: 1873-1880.
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  16. Odimegwu, D.C., V.C. Okore and C.O. Esimone, 2016. Analyses of Ramalina farinaceae extract anti-proliferative activities in the culture of Mammalian cells and splenocytes. Res. J. Med. Plants, 10: 303-308.

  17. Obitte, N.C., J.C. Ndefo, K. Okoye, L. Ezichi, O.L. Ugorji, D.C. Odimegwu and D.C. Ibe, 2016. Preliminary microbiological and flow behaviour of some vaginal microbicide gels. Transylvanian Rev., 24: 677-683.

  18. Okoye, F.B.C., D.C. Odimegwu, C.N. Anyasor, D.L. Ajaghaku, T.H. Gugu, P.O. Osadebe and P. Proksch, 2015. A new antioxidant and antimicrobial compound isolated from Alchornea cordifolia leaves. Afr. J. Pharm. Res. Dev., 7: 87-94.

  19. Odimegwu, D.C., C. Ejikeugwu and C.O. Esimone, 2015. Lichen Secondary Metabolites as Possible Antiviral Agents. In: Lichen Secondary Metabolites, Rankovic, B. (Ed.). Springer International Publishing, Germany, ISBN: 978-3-319-13374-4, pp: 165-177.

  20. Afunwa, R.A., D.C. Odimegwu, R.I. Iroha and C.O. Esimone, 2014. Antibiotic combinatorial approach utilized against extended spectrum beta-lactamase (ESBL) bacteria isolates from Enugu, South Eastern Nigeria. J. Health Sci., 4: 19-25.

  21. Lai, D., D.C. Odimegwu, C. Esimone, T. Grunwald and P. Proksch, 2013. Phenolic compounds with in vitro activity against respiratory syncytial virus from the Nigerian lichen Ramalina farinacea. Planta Medica, 79: 1440-1446.
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  22. Dibua, U.M.E., J.A.C. Ugonabo, D. Oladepo, I.R. Iroha and D.C. Odimegwu, 2013. Genital Chlamydia and HIV co-infection: Adverse pregnancy outcomes. Am. J. Res. Commun., 1: 470-500.

  23. Oleghe, P.O., D.C. Odimegwu, E. Udofia and C.O. Esimone, 2011. Multi-drug-resistant bacteria isolates recovered from herbal medicinal preparations in a southern Nigerian setting. J. Rural Trop. Public Health, 10: 70-75.
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  24. Ogbonna, J.D.N., P.O. Nnamani, V.C. Okore and D.C. Odimegwu, 2011. Adsorption. In: Laboratory Techniques in Pharmaceutical Microbiology, Okore, V.C. and K.C. Ofokansi (Eds.). Praise House Publishers, Enugu, pp: 14-17.

  25. Odimegwu, D.C., T. Grunwald and C.O. Esimone, 2011. Anti-Respiratory Syncytial Virus Agents from Phytomedicine. In: Human Respiratory Syncytial Virus Infection, Resch, B. (Ed.). InTech Publisher, Bosnia, ISBN: 9789533077185, pp: 179-196.

  26. Odimegwu, D.C., F.I. Uche, C.L. Ozioko, C.E. Ogbuanya, H.T. Gugu and C.O. Esimone, 2011. In vitro antimicrobial evaluation of methanol extract of Triumfetta rhomboidea leaves against some clinical bacterial isolates. Int. J. Biol. Chem. Sci., 5: 1970-1977.
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  27. Odimegwu, D.C., E.C. Ibezim, M.U. Adikwu, J.A.E. Boniface, H.I. Ogbu and C.O. Esimone, 2011. Bioassay-tracked temperature-stress-induced chemical degradation of bio-active wound healing antibacterial extract of Dissotis theifolia stem dispersed in a pharmaceutical cream and ointment. Int. J. Applied Res. Nat. Prod., 4: 20-28.

  28. Nnamani, P.O., D.C. Odimegwu and K.C. Ofokansi, 2011. Evaluation of Antiseptics. In: Laboratory Techniques in Pharmaceutical Microbiology, Okore, V.C. and K.C. Ofokansi (Eds.). Praise House Publishers, Enugu, pp: 24-26.

  29. Ngwoke, K.G., D.C. Odimegwu and C.O. Esimone, 2011. Antimicrobial Natural Products. In: Science Against Microbial Pathogens: Communicating Current Research and Technological Advances, Mendz-Vilas, A. (Ed.). Formatex Research Center, Badajoz, Spain, pp: 1011-1026.

  30. Kenechukwu, F.C., D.C. Odimegwu, P.O. Nnamani and V.C. Okore, 2011. Diffusion. In: Laboratory Techniques in Physical Pharmaceutics, Attama, A.A. and E.C. Ibezim (Eds.). Praise House Publishers, Enugu, pp: 18-19.

  31. Ibezim, E.C., F.C. Kenechukwu, D.C. Odimegwu, P.F. Builders and B. Kabele-Toge et al., 2011. Antimicrobial efficacy of a syrup formulation from methanol extract of Garcinia kola seed. Afr. J. Pharm. Res. Dev., 3: 22-27.

  32. Ibezim, E.C., C.T. Andrade, C. Marcia, B. Barretto, D.C. Odimegwu and F.F. de Lima, 2011. Ionically cross-linked chitosan/tripolyphosphate microparticles for the controlled delivery of pyrimethamine. Ibnosina J. Med. Biomed. Sci., 3: 77-88.
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  33. Anejionu, M.G., E.I. Nweze, E.U. Dibua, D.C. Odimegwu, E.I. Okoye and C.O. Esimone, 2011. The in vitro antifungal activity of the combinations of Mitracarpus scaber and Occimum gratissimum herbal extracts and some Non-steroidal Anti-inflammatory drugs. Microbiol. J., 1: 181-190.
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  34. Afunwa, R.A., D.C. Odimegwu, R.I. Iroha and C.O. Esimone, 2011. Antimicrobial resistance status and prevalence rates of extended spectrum beta-lactamase producers isolated from a mixed human population. Bosnian J. Basic Med. Sci., 11: 91-96.
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  35. Njoku, O.U., J.A.E. Boniface, N.C. Obitte D.C. Odimegwu and H.I. Ogbu, 2010. Some nutriceutical potential of beniseed oil. Int. J. Applied Res. Nat. Prod., 2: 11-19.
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  36. Esimone, C.O., F.B.C. Okoye, D.C. Odimegwu, C.S. Nworu, P.O. Oleghe and P.W. Ejogha, 2010. In vitro antimicrobial evaluation of lozenges containing extract of garlic and ginger. Int. J. Health Res., 3: 105-110.
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  37. Ugwu, M.C., D.C. Odimegwu, E.C. Ibezim and C.O. Esimone, 2009. resistance patterns of Staphylococcus aureus isolated from nostrils of healthy human subjects in a southeastern Nigeria locality. Macedonian J. Med. Sci., 2: 294-300.
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  38. Ofokansi, K.C., E.C. Ibezim, P.A. Akpa, D.C. Odimegwu and M.U. Adikwu, 2009. Sterilization Methods. In: Laboratory Techniques in Pharmaceutical Microbiology, Okore, V.C. and K.C. Ofokansi (Eds.). Praise House Publishers, Enugu, pp: 1-43.

  39. Odimegwu, D.C., E.B. Onuigbo, D.B. Uzuegbu and P.O. Nnamani, 2009. Polymers in Physical Sciences. In: Polymers and Polymer Applications, Attama, A.A. and C.O. Esimone (Eds.). Jolyn Pub., Nsukka, pp: 83-100.

  40. Obitte, N.C., A. Chukwu, D.C. Odimegwu and V.C. Nwoke, 2009. Survey of drug storage practice in homes, hospitals and patent medicine stores in Nsukka Nigeria. Sci. Res. Essay, 4: 1354-1359.

  41. Ngwu, M.I., M.U. Adikwu, E.C. Ibezim, D.C. Odimegwu, G.I. Ngwu and C.O. Esimone, 2009. In vitro evaluation of the susceptibility pattern of some resistant and non-resistant bacteria strains to a combine activity of herbal preparation of Azadirachta indica and some antibiotics. Int. J. Health Res., 2: 279-286.

  42. Esimone, C.O., D.B. Uzuegbu and D.C. Odimegwu, 2009. Dispensing of Sterile Formulations. In: Basic Laboratory Dispensing Techniques, Ibezim, E.C. and K.C. Ofokansi (Eds.). Jolyn Pub., Nsukka, pp: 43-45.

  43. Attama, A.A., P.O. Nnamani and D.C. Odimegwu, 2009. General Dispensing Considerations. In: Basic Laboratory Dispensing Techniques, Ibezim, E.C. and K.C. Ofokansi (Eds.). Jolyn Pub., Nsukka, pp: 5-11.

  44. Odimegwu, D.C., E.C. Ibezim, C.O. Esimone, C.S. Nworu and F.B.C., Okoye, 2008. Wound healing and antibacterial activities of the extract of Dissotis theifolia (Melastomataceae) stem formulated in a simple ointment base. J. Med. Plants Res., 2: 11-16.
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  45. Ibezim, E.C., D.C. Odimegwu and M.U. Adikwu, 2008. Sources of Microbial Contamination. In: Laboratory Techniques in Basic Pharmaceutical Microbiology, Okore, V.C. and A.A. Attama (Eds.). Jolyn Pub., Nsukka, pp: 16-18.

  46. Odimegwu, D.C., E.C. Ibezim, C.O. Esimone and K.F. Chah, 2007. Antimicrobial and wound healing effect of methanolic extract of Dissotis theifolia formulated as cream. J. Med. Pharm. Sci., 3: 33-36.

  47. Esimone, C.O., M.U. Adikwu, C.S. Nworu, F.B.C. Okoye and D.C. Odimegwu, 2007. Adaptogenic potentials of Camellia sinensis leaves, Garcinia kola and Kola nitida seeds. Sci. Res. Essay, 2: 232-237.
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  48. Esimone, C.O., C.S. Nworu, M.U. Adikwu, D.C. Odimegwu and C.O. Ezugwu, 2007. The effect of a new adaptogen, Garcinia kola seed, on the bioavailability of ofloxacin in humans. Scient. Res. Essays, 2: 482-485.