Dr. Lawal Akeem Olalekan
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Dr. Lawal Akeem Olalekan

Head of Academic Department/Faculty
Lagos State University College of Medicine, Nigeria

Highest Degree
Ph.D. in Molecular Sciences from University of Strathclyde, UK

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Area of Interest:

Molecular Sciences
Cell Culture Technique
Agarose Gel Electrophoresis
Western Blotting
Enzyme Assay

Research Publications in Numbers


Selected Publications

  1. Lawal, A.O., L.M. Davids and J.L. Marnewick, 2016. Diesel exhaust particles and endothelial cells dysfunction: An update. Toxicol. in Vitro, 32: 92-104.
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  2. Lawal, A.O., J.L. Marnewick and E.M. Ellis, 2015. Heme oxygenase-1 attenuates cadmium-induced mitochondrial-caspase 3-dependent apoptosis in human hepatoma cell line. BMC Pharmacol. Toxicol., 16: 1-15.
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  3. Lawal, A., M. Zhang, M. Dittmar, A. Lulla and J.A. Araujo, 2015. Heme oxygenase-1 protects endothelial cells from the toxicity of air pollutant chemicals. Toxicol. Applied Pharmacol. 10.1016/j.taap.2015.01.010.
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  4. Lawal, O. and E.M. Ellis, 2014. 2D-Gel electrophoresis analysis of proteomic changes in three human cell lines; HEK 293, HepG2 and 1321N1 cells in response to cadmium. Curr. Proteomics, 11: 27-36.
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  5. Yin, F., A. Lawal, J. Ricks, J.R. Fox and T. Larson et al., 2013. Diesel exhaust induces systemic lipid peroxidation and development of dysfunctional pro-oxidant and pro-inflammatory high-density lipoprotein. Arteriosclerosis, Thrombosis Vascular Biol., 33: 1153-1161.
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  6. Miller, M.R., S.G. McLean, R. Duffin, A.O. Lawal and J.A. Araujo et al., 2013. Diesel exhaust particulate increases the size and complexity of lesions in atherosclerotic mice. Part. Fibre Toxicol., Vol. 10. 10.1186/1743-8977-10-61.
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  7. Lawal, O. and J.A. Araujo, 2012. Particulate Matter and Cardiovascular Health Effects. In: Air Pollution-Monitoring, Modelling and Health, Khare, M. (Ed.). Intech, Croatia, pp: 369-386.
  8. Lawal, A.O. and E.M. Ellis, 2012. Phospholipase C mediates cadmium‐dependent apoptosis in HEK 293 cells. Basic Clin. Pharmacol. Toxicol., 110: 510-517.
    CrossRef  |  
  9. Lawal, A.O., E.O. Farombi and A.F. Lawal, 2011. Aqueous extract of potato (Solanum tuberosum) modulates cadmium-induced liver damage in female wistar rats. Int. J. Pharmacol., 7: 599-607.
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  10. Lawal, A.O., A.F. Lawal, A. Ologundudu, O.Y. Adeniran, A. Omonkhua and F. Obi, 2011. Antioxidant effects of heated garlic juice on cadmium-induced liver damage in rats as compared to ascorbic acid. J. Toxicol. Sci., 36: 549-557.
    CrossRef  |  
  11. Lawal, A.O. and E.M. Ellis, 2011. The chemopreventive effects of aged garlic extract against cadmium-induced toxicity. Environ. Toxicol. Pharmacol., 32: 266-274.
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  12. Lawal, A.O. and E.M. Ellis, 2011. Nrf2-mediated adaptive response to cadmium-induced toxicity involves protein kinase C delta in human 1321N1 astrocytoma cells. Environ. Toxicol. Pharmacol., 32: 54-62.
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  13. Lawal, A.O. and E. Ellis, 2010. Differential sensitivity and responsiveness of three human cell lines HepG2, 1321N1 and HEK 293 to cadmium. J. Toxicol. Sci., 35: 465-478.
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  14. Ologundudu, A., A.O. Lawal, I.A. Ololade, A.A. Omonkhua and F.O. Obi, 2008. The antiulcerogenic activity of aqueous extract of Carica papaya fruits on aspirin induced ulcer in rats. Int. J. Toxicol., 5: 1-8.
  15. Ogungbe, I.V. and A.O. Lawal, 2008. The protective effect of ethanolic extracts of garlic and ascorbic acid on cadmium-induced oxidative stress. J. Biol. Sci., 8: 181-185.
  16. Omonkhua, A.A., B.O. Agoreyo, O.Y. Adeniran, A.O. Lawal, O. Adeyemi and A. Ologundudu, 2006. Changes in the activities of some carbohydrate degrading enzymes during ripening of Musa paradisiaca and Musa sapientum. Asian J. Plant Sci., 5: 147-149.
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  17. Ologundudu, A., A.O. Lawal, O.G. Adesina and F.O. Obi, 2006. Effect of ethanolic extract of Hibiscus sabdariffa L. on 2, 4-dinitrophenylhydrazine-induced changes in blood parameters in rabbits. Global J. Pure Applied Sci., 12: 335-338.
  18. Lawal, A.O., A. Ologundudu, F.O. Obi, I.V. Ogungbe and A.O. Olakanye et al., 2006. Antioxidant effects of aqueous extract of sweet potato and ascorbic acid on paracetamol induced damage. J. Med. Sci., 6: 87-92.
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  19. Adeniran, O.Y., M.A. Fafunso, O. Adeyemi, A.O. Lawal, A. Ologundudu and A.A. Omonkhua, 2006. Biochemical effects of pesticides on serum and urinological system of rats. J. Applied Sci., 6: 668-672.
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