Dr. Lawal Akeem Olalekan

Dr. Lawal Akeem Olalekan

Head of Academic Department/Faculty
Lagos State University College of Medicine, Nigeria


Highest Degree
Ph.D. in Molecular Sciences from University of Strathclyde, UK

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Area of Interest:

Molecular Sciences
100%
Cell Culture Technique
62%
Agarose Gel Electrophoresis
90%
Western Blotting
75%
Enzyme Assay
55%

Selected Publications

  1. Lawal, A.O., L.M. Davids and J.L. Marnewick, 2016. Diesel exhaust particles and endothelial cells dysfunction: An update. Toxicol. In Vitro, 32: 92-104.
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  2. Lawal, A.O., J.L. Marnewick and E.M. Ellis, 2015. Heme oxygenase-1 attenuates cadmium-induced mitochondrial-caspase 3-dependent apoptosis in human hepatoma cell line. BMC Pharmacol. Toxicol., 16: 1-15.
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  3. Lawal, A., M. Zhang, M. Dittmar, A. Lulla and J.A. Araujo, 2015. Heme oxygenase-1 protects endothelial cells from the toxicity of air pollutant chemicals. Toxicol. Applied Pharmacol. 10.1016/j.taap.2015.01.010.
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  4. Lawal, O. and E.M. Ellis, 2014. 2D-Gel electrophoresis analysis of proteomic changes in three human cell lines; HEK 293, HepG2 and 1321N1 cells in response to cadmium. Curr. Proteomics, 11: 27-36.
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  5. Yin, F., A. Lawal, J. Ricks, J.R. Fox and T. Larson et al., 2013. Diesel exhaust induces systemic lipid peroxidation and development of dysfunctional pro-oxidant and pro-inflammatory high-density lipoprotein. Arteriosclerosis, Thrombosis Vascular Biol., 33: 1153-1161.
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  6. Miller, M.R., S.G. McLean, R. Duffin, A.O. Lawal and J.A. Araujo et al., 2013. Diesel exhaust particulate increases the size and complexity of lesions in atherosclerotic mice. Particle Fibre Toxicol., Vol. 10. 10.1186/1743-8977-10-61.
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  7. Lawal, O. and J.A. Araujo, 2012. Particulate Matter and Cardiovascular Health Effects. In: Air Pollution-Monitoring, Modelling and Health, Khare, M. (Ed.). Intech, Croatia, pp: 369-386.
  8. Lawal, A.O. and E.M. Ellis, 2012. Phospholipase C mediates cadmium‐dependent apoptosis in HEK 293 cells. Basic Clin. Pharmacol. Toxicol., 110: 510-517.
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  9. Lawal, A.O., E.O. Farombi and A.F. Lawal, 2011. Aqueous extract of potato (Solanum tuberosum) modulates cadmium-induced liver damage in female wistar rats. Int. J. Pharmacol., 7: 599-607.
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  10. Lawal, A.O., A.F. Lawal, A. Ologundudu, O.Y. Adeniran, A. Omonkhua and F. Obi, 2011. Antioxidant effects of heated garlic juice on cadmium-induced liver damage in rats as compared to ascorbic acid. J. Toxicol. Sci., 36: 549-557.
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  11. Lawal, A.O. and E.M. Ellis, 2011. The chemopreventive effects of aged garlic extract against cadmium-induced toxicity. Environ. Toxicol. Pharmacol., 32: 266-274.
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  12. Lawal, A.O. and E.M. Ellis, 2011. Nrf2-mediated adaptive response to cadmium-induced toxicity involves protein kinase C delta in human 1321N1 astrocytoma cells. Environ. Toxicol. Pharmacol., 32: 54-62.
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  13. Lawal, A.O. and E. Ellis, 2010. Differential sensitivity and responsiveness of three human cell lines HepG2, 1321N1 and HEK 293 to cadmium. J. Toxicol. Sci., 35: 465-478.
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  14. Ologundudu, A., A.O. Lawal, I.A. Ololade, A.A. Omonkhua and F.O. Obi, 2008. The antiulcerogenic activity of aqueous extract of Carica papaya fruits on aspirin induced ulcer in rats. Int. J. Toxicol., 5: 1-8.
  15. Ogungbe, I.V. and A.O. Lawal, 2008. The protective effect of ethanolic extracts of garlic and ascorbic acid on cadmium-induced oxidative stress. J. Biol. Sci., 8: 181-185.
  16. Omonkhua, A.A., B.O. Agoreyo, O.Y. Adeniran, A.O. Lawal, O. Adeyemi and A. Ologundudu, 2006. Changes in the activities of some carbohydrate degrading enzymes during ripening of Musa paradisiaca and Musa sapientum. Asian J. Plant Sci., 5: 147-149.
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  17. Ologundudu, A., A.O. Lawal, O.G. Adesina and F.O. Obi, 2006. Effect of ethanolic extract of Hibiscus sabdariffa L. on 2, 4-dinitrophenylhydrazine-induced changes in blood parameters in rabbits. Global J. Pure Applied Sci., 12: 335-338.
  18. Lawal, A.O., A. Ologundudu, F.O. Obi, I.V. Ogungbe and A.O. Olakanye et al., 2006. Antioxidant effects of aqueous extract of sweet potato and ascorbic acid on paracetamol induced damage. J. Med. Sci., 6: 87-92.
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  19. Adeniran, O.Y., M.A. Fafunso, O. Adeyemi, A.O. Lawal, A. Ologundudu and A.A. Omonkhua, 2006. Biochemical effects of pesticides on serum and urinological system of rats. J. Applied Sci., 6: 668-672.
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