Dr. Legesse Adane Bahiru

Dr. Legesse Adane Bahiru

Associate Professor
Hawassa University, Ethiopia


Highest Degree
Ph.D. in Medicinal Chemistry from National Institute of Pharmaceutical Education and Research, Mohali, India

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Area of Interest:

Chemistry
100%
Organic Chemistry
62%
Medicinal Chemistry
90%
Antimalarial Agents
75%
Pharmaceutical Chemistry
55%

Selected Publications

  1. Adane, L., 2020. Preparation of laundry soap from used cooking oils: getting value out of waste. Sci. Res. Essays, 15: 1-10.
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  2. Bekeri, D., L., Adane and F. Mamo, 2018. Test for flavonoids: flavonoids were tested using test for saponins: froth test. https://www.semanticscholar.org/paper/Test-for-Flavonoids-%3A-Flavonoids-were-tested-using-Bekeri-Adane/e5e59201786dc10fccf4190807a80e2c0f70cbb0.
  3. Adane L., F. Tamiru and B. Bekele, 2018. Phytochemical screening of root extract of momordica boivinii and isolation of two steroids. Research Journal of Phytochemistry 12: 21-34.
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  4. Bhagat, S., M. Arfeen, L. Adane, S. Singh, P.P. Singh, A.K. Chakraborti and P.V. Bharatam, 2017. Guanylthiourea derivatives as potential antimalarial agents: Synthesis, in vivo and molecular modelling studies. Eur. J. Med. Chem., 135: 339-348.
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  5. Legesse, A., A. Muluken and A. Getasew, 2016. A survey on awareness of consumers about health problems of food additives in packaged foods and their attitude toward consumption of packaged foods: A case study at Jimma University. Int. Food Res. J., 23: 884-890.
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  6. Addisu, D., L. Adane and P. Vijayalakshmi, 2016. Phytochemical investigation and evaluation of minimum antibacterial inhibitory concentrations of methanolic extracts of the root and leaves of Aloe yavellana. Middle-East J. Scient. Res., 12: 190-195.
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  7. Kumar, D., P.S. Jadhavar, M. Nautiyal, H. Sharma and P.K. Meena et al., 2015. Convenient synthesis of 2,3-disubstituted quinazolin-4(3H)-ones and 2-styryl-3-substituted quinazolin-4(3H)-ones: Applications towards the synthesis of drugs. RSC Adv., 5: 30819-30825.
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  8. Edilu, A., L. Adane and D. Woyessa, 2015. In vitro antibacterial activities of compounds isolated from roots of Caylusea abyssinica. Ann. Clin. Microbiol. Antimicrob., Vol. 14. 10.1186/s12941-015-0072-6.
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  9. Edilu, A., L. Adane and D. Woyesa, 2014. Evaluation of antibacterial activities and phytochemical screening of the crude extracts of roots of Caylusea abyssinica (Fresen.). Middle-East J. Scient. Res., 22: 960-965.
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  10. Biftu, A., L. Adane and Y. Tariku, 2014. Evaluation of antibacterial activities of compounds isolated from fruits of Sida rhombifolia Linn. Middle-East J. Scient. Res., 22: 681-689.
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  11. Adane, L., S. Bhagat, M. Arfeen, S. Bhatia and R. Sirawaraporn et al., 2014. Design and synthesis of guanylthiourea derivatives as potential inhibitors of Plasmodium falciparum dihydrofolate reductase enzyme. Bioorg. Med. Chem. Lett., 24: 613-617.
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  12. Tesemma, M., L. Adane, Y. Tariku, D. Muleta and S. Demise, 2013. Isolation of compounds from acetone extract of root wood of Moringa stenopetala and evaluation of their antibacterial activities. Res. J. Med. Plants, 7: 32-47.
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  13. Bekele, B., L. Adane, Y. Tariku and A. Hailu, 2013. Evaluation of antileishmanial activities of triglycerides isolated from roots of Moringa stenopetala. Med. Chem. Res., 22: 4592-4599.
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  14. Woldeyes, S., L. Adane, Y. Tariku, D. Muleta and T. Begashaw, 2012. Evaluation of antibacterial activities of compounds isolated from Sida rhombifolia Linn. (Malvaceae). Nat. Prod. Chem. Res., Vol. 1. 10.4172/2329-6836.1000101.
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  15. Gelaw, H., L. Adane, Y. Tariku and A. Hailu, 2012. Isolation of crotepoxide from berries of Croton macrostachyus and evaluation of its anti-leishmanial activity. J. Pharmacogn. Phytochem., 1: 15-24.
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  16. Adane, L. and A. Abeje, 2012. Assessment of familiarity and understanding of chemical hazard warning signs among university students majoring chemistry and biology: A case study at Jimma University, Southwestern Ethiopia. World Applied Sci. J., 16: 290-299.
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  17. Adane, L. and P.V. Bharatam, 2011. Computer-aided molecular design of 1H-imidazole-2,4-diamine derivatives as potential inhibitors of Plasmodium falciparum DHFR enzyme. J. Mol. Model., 17: 657-667.
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  18. Adane, L. and D. Muleta, 2011. Survey on the usage of plastic bags, their disposal and adverse impacts on environment: A case study in Jimma City, Southwestern Ethiopia. J. Toxicol. Environ. Health Sci., 3: 234-248.
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  19. Adane, L. and A. Admas, 2011. Relevance and safety of chemistry laboratory experiments from students' perspective: A case study at Jimma University, Southwestern Ethiopia. Educ. Res., 2: 1749-1758.
  20. Mehdi, A., L. Adane, D.S. Patel and P.V. Bharatam, 2010. Electronic structure and reactivity of guanylthiourea: A quantum chemical study. J. Comput. Chem., 31: 1259-1267.
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  21. Alemayehu, G., L. Adane and B.M. Abegaz, 2010. A new bianthracene C-arabinopyranoside from Senna septemtrionalis. Nat. Prod. Commun. 5: 747-750.
    PubMed  |  
  22. Adane, L., P.V. Bharatam and V. Sharma, 2010. A common feature-based 3D-pharmacophore model generation and virtual screening: Identification of potential PfDHFR inhibitors. J. Enzyme Inhib. Med. Chem., 25: 635-645.
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  23. Adane, L., D. Patel and P.V. Bharatam, 2010. Shape- and chemical feature-based 3D-pharmacophore model generation and virtual screening: Identification of potential leads for P. falciparum DHFR enzyme inhibition. Chem. Biol. Drug Des., 75: 115-126.
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  24. Adane, L. and P.V. Bharatam, 2010. Binding interactions of PfDHFR enzyme inhibitors in the active site: Molecular docking studies. Indian J. Pharm. Sci., 72: 324-333.
  25. Adane, L. and P.V. Bharatam, 2009. 3D-QSAR analysis of cycloguanil derivatives as inhibitors of A16V + S108T mutant Plasmodium falciparum dihydrofolate reductase enzyme. J. Mol. Graph. Modell., 28: 357-367.
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  26. Adane, L. and P.V. Bharatam, 2008. Tautomeric preferences and electron delocalization in biurets, thiobiurets and dithiobiurets: An ab initio study. Int. J. Quantum Chem., 108: 1277-1286.
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  27. Adane, L. and P.V. Bharatam, 2008. Modelling and informatics in the analysis of P. falciparum DHFR enzyme inhibitors. Curr. Med. Chem., 15: 1552-1569.
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  28. Bharatam, P.V., D.S. Patel, L. Adane, A. Mittal and S. Sundriyal, 2007. Modeling and informatics in designing anti-diabetic agents. Curr. Pharmaceut. Des., 13: 3518-3530.
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