Dr. Legesse Adane Bahiru
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Dr. Legesse Adane Bahiru

Professor
Hawassa University, Ethiopia

Highest Degree
Ph.D. in Medicinal Chemistry from National Institute of Pharmaceutical Education and Research, Mohali, India

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Area of Interest:

Chemistry
100%
Organic Chemistry
62%
Medicinal Chemistry
90%
Antimalarial Agents
75%
Pharmaceutical Chemistry
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
33
Abstracts
0

Selected Publications

  1. Legesse, A., T. Motuma, T. Fillipo, W. Adrian and S. Matthew, 2023. Extraction and characterization of oil from Trichilia dregeana (Luya) seed beans and seed shells. J. Appl. Sci. Environ. Manage., 27: 607-614.
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  2. Legesse, A., T. Abera and T. Tegene, 2023. Determination of caffeine content of Nensebo coffee beans Southern Ethiopia, using ultra violet-visible (UV/V) is and high performance liquid chromatography (HPLC) methods in Ethiopia. Afr. J. Pure Appl. Chem., 17: 21-31.
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  3. Ameja, L.B., M.T. Ayana, Z.B. Derese, Y. Tariku, F.A. Yihun, M.T. Kassa and L.A. Bahiru, 2022. Qualitative phytochemical exploration guided in vitro antibacterial activity studies on crude stem bark extract of stereospermum kunthainum (Bignoniaceae). 31 January 2022, Preprint (Version 1) available at Research Square https://doi.org/10.21203/rs.3.rs-1294105/v1.
  4. Tole, T.T., E. Diriba and L.A. Bahiru, 2021. Bioactive compounds from Croton macrostachyus and Commiphora habessinica occurring in Ethiopia. Adv. Trad. Med., 10.1007/s13596-021-00570-x.
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  5. Teshome, M., L. Adane and Y. Tariku, 2021. Phytochemical screening and evaluation of antibacterial activities of root bark extracts of Moringa stenopetala. Res. J. Medic. Plants, 15: 1-6.
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  6. Legesse, A., A. Habtamu and T. Tegene, 2021. Use of jatropha seed oil and alkali solution obtained from its ash for soap making. J. Appl. Sci. Environ. Manage., 24: 2005-2015.
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  7. Adane, L., T. Gelaye and T. Tesfaye, 2021. Exploring of the potential of parthenium weed ash as substitute for commercial alkali for preparation of laundry soap: as a means to control invasion of parthenium. Front. Sustainability, Vol. 2. 10.3389/frsus.2021.607125.
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  8. Keneni, Y.G., L.A. Bahiru and J.M. Marchetti, 2020. Effects of different extraction solvents on oil extracted from jatropha seeds and the potential of seed residues as a heat provider. Bioenergy Res., 10.1007/s12155-020-10217-5.
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  9. Adane, L., 2020. Preparation of laundry soap from used cooking oils: getting value out of waste. Sci. Res. Essays, 15: 1-10.
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  10. Bekeri, D., L., Adane and F. Mamo, 2018. Test for flavonoids: flavonoids were tested using test for saponins: froth test. https://www.semanticscholar.org/paper/Test-for-Flavonoids-%3A-Flavonoids-were-tested-using-Bekeri-Adane/e5e59201786dc10fccf4190807a80e2c0f70cbb0.
  11. Adane L., F. Tamiru and B. Bekele, 2018. Phytochemical screening of root extract of momordica boivinii and isolation of two steroids. Research Journal of Phytochemistry 12: 21-34.
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  12. Bhagat, S., M. Arfeen, L. Adane, S. Singh, P.P. Singh, A.K. Chakraborti and P.V. Bharatam, 2017. Guanylthiourea derivatives as potential antimalarial agents: Synthesis, in vivo and molecular modelling studies. Eur. J. Med. Chem., 135: 339-348.
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  13. Legesse, A., A. Muluken and A. Getasew, 2016. A survey on awareness of consumers about health problems of food additives in packaged foods and their attitude toward consumption of packaged foods: A case study at Jimma University. Int. Food Res. J., 23: 884-890.
    Direct Link  |  
  14. Addisu, D., L. Adane and P. Vijayalakshmi, 2016. Phytochemical investigation and evaluation of minimum antibacterial inhibitory concentrations of methanolic extracts of the root and leaves of Aloe yavellana. Middle-East J. Scient. Res., 12: 190-195.
    Direct Link  |  
  15. Kumar, D., P.S. Jadhavar, M. Nautiyal, H. Sharma and P.K. Meena et al., 2015. Convenient synthesis of 2,3-disubstituted quinazolin-4(3H)-ones and 2-styryl-3-substituted quinazolin-4(3H)-ones: Applications towards the synthesis of drugs. RSC Adv., 5: 30819-30825.
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  16. Edilu, A., L. Adane and D. Woyessa, 2015. In vitro antibacterial activities of compounds isolated from roots of Caylusea abyssinica. Ann. Clin. Microbiol. Antimicrob., Vol. 14. 10.1186/s12941-015-0072-6.
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  17. Edilu, A., L. Adane and D. Woyesa, 2014. Evaluation of antibacterial activities and phytochemical screening of the crude extracts of roots of Caylusea abyssinica (Fresen.). Middle-East J. Scient. Res., 22: 960-965.
    Direct Link  |  
  18. Biftu, A., L. Adane and Y. Tariku, 2014. Evaluation of antibacterial activities of compounds isolated from fruits of Sida rhombifolia Linn. Middle-East J. Scient. Res., 22: 681-689.
    Direct Link  |  
  19. Adane, L., S. Bhagat, M. Arfeen, S. Bhatia and R. Sirawaraporn et al., 2014. Design and synthesis of guanylthiourea derivatives as potential inhibitors of Plasmodium falciparum dihydrofolate reductase enzyme. Bioorg. Med. Chem. Lett., 24: 613-617.
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  20. Tesemma, M., L. Adane, Y. Tariku, D. Muleta and S. Demise, 2013. Isolation of compounds from acetone extract of root wood of Moringa stenopetala and evaluation of their antibacterial activities. Res. J. Med. Plants, 7: 32-47.
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  21. Bekele, B., L. Adane, Y. Tariku and A. Hailu, 2013. Evaluation of antileishmanial activities of triglycerides isolated from roots of Moringa stenopetala. Med. Chem. Res., 22: 4592-4599.
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  22. Woldeyes, S., L. Adane, Y. Tariku, D. Muleta and T. Begashaw, 2012. Evaluation of antibacterial activities of compounds isolated from Sida rhombifolia Linn. (Malvaceae). Nat. Prod. Chem. Res., Vol. 1. 10.4172/2329-6836.1000101.
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  23. Gelaw, H., L. Adane, Y. Tariku and A. Hailu, 2012. Isolation of crotepoxide from berries of Croton macrostachyus and evaluation of its anti-leishmanial activity. J. Pharmacogn. Phytochem., 1: 15-24.
    Direct Link  |  
  24. Adane, L. and A. Abeje, 2012. Assessment of familiarity and understanding of chemical hazard warning signs among university students majoring chemistry and biology: A case study at Jimma University, Southwestern Ethiopia. World Applied Sci. J., 16: 290-299.
    Direct Link  |  
  25. Adane, L. and P.V. Bharatam, 2011. Computer-aided molecular design of 1H-imidazole-2,4-diamine derivatives as potential inhibitors of Plasmodium falciparum DHFR enzyme. J. Mol. Model., 17: 657-667.
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  26. Adane, L. and D. Muleta, 2011. Survey on the usage of plastic bags, their disposal and adverse impacts on environment: A case study in Jimma City, Southwestern Ethiopia. J. Toxicol. Environ. Health Sci., 3: 234-248.
    Direct Link  |  
  27. Adane, L. and A. Admas, 2011. Relevance and safety of chemistry laboratory experiments from students' perspective: A case study at Jimma University, Southwestern Ethiopia. Educ. Res., 2: 1749-1758.
  28. Mehdi, A., L. Adane, D.S. Patel and P.V. Bharatam, 2010. Electronic structure and reactivity of guanylthiourea: A quantum chemical study. J. Comput. Chem., 31: 1259-1267.
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  29. Alemayehu, G., L. Adane and B.M. Abegaz, 2010. A new bianthracene C-arabinopyranoside from Senna septemtrionalis. Nat. Prod. Commun. 5: 747-750.
    PubMed  |  
  30. Adane, L., P.V. Bharatam and V. Sharma, 2010. A common feature-based 3D-pharmacophore model generation and virtual screening: Identification of potential PfDHFR inhibitors. J. Enzyme Inhib. Med. Chem., 25: 635-645.
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  31. Adane, L., D. Patel and P.V. Bharatam, 2010. Shape- and chemical feature-based 3D-pharmacophore model generation and virtual screening: Identification of potential leads for P. falciparum DHFR enzyme inhibition. Chem. Biol. Drug Des., 75: 115-126.
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  32. Adane, L. and P.V. Bharatam, 2010. Binding interactions of PfDHFR enzyme inhibitors in the active site: Molecular docking studies. Indian J. Pharm. Sci., 72: 324-333.
  33. Adane, L. and P.V. Bharatam, 2009. 3D-QSAR analysis of cycloguanil derivatives as inhibitors of A16V + S108T mutant Plasmodium falciparum dihydrofolate reductase enzyme. J. Mol. Graph. Modell., 28: 357-367.
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  34. Adane, L. and P.V. Bharatam, 2008. Tautomeric preferences and electron delocalization in biurets, thiobiurets and dithiobiurets: An ab initio study. Int. J. Quantum Chem., 108: 1277-1286.
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  35. Adane, L. and P.V. Bharatam, 2008. Modelling and informatics in the analysis of P. falciparum DHFR enzyme inhibitors. Curr. Med. Chem., 15: 1552-1569.
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  36. Bharatam, P.V., D.S. Patel, L. Adane, A. Mittal and S. Sundriyal, 2007. Modeling and informatics in designing anti-diabetic agents. Curr. Pharmaceut. Des., 13: 3518-3530.
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