Biography

Sechene Stanley Gololo, holds a Ph.D degree in Biochemistry and is currently attached to the department of Biochemistry at Sefako Makgatho Health Sciences University. Dr Gololo is an emerging Scientific Researcher with several publications in scientific journals. Dr Gololo has a research interest in the phytochemical composition and biological activites of medicinal plants used by local traditional healers in South Africa. He has experience in the isolation and identification of bioactive compounds from plant extracts.Currently, Dr Gololo is investigating the effect that environmental factors have on the phytochemical composition of medicinal plants in South Africa.

Area of Interest:

Plant and Soil Sciences

100%

Medicinal Plant

62%

Bioassays

90%

Phytochemical Analysis

75%

Natural Products

55%

Research Publications in Numbers

Books
3

Chapters
0

Articles
13

Abstracts
21

Selected Publications

Gololo, S.S., C.J. Semenya, M.T. Olivier, L.J. Sethoga, E.H. Mathe and R.B. Maseko, 2021. Metabolite profiling of different tissues of Barleria dinteri through the GC-MS analysis. Asian J. Chem., 33: 1336-1340.
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Olivier, M.T., F.M. Muganza, L.J. Shai and S.S. Gololo, 2020. Rutin inhibits F, G, N and O gonorrhea strains, 2008 who N-gonorrhea reference strains, in vitro. Interdiscip. Res. J. Arch., 1: 41-49.
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Ndwandwe, S.L., M.T. Olivier and S.S. Gololo, 2020. Antioxidant and antidiabetic activities of flavonoid derivative compounds isolated from Sclerocarya birrea leaves. Asian J. Chem., 33: 57-61.
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Mncube, S.C., S.S. Gololo and M.A. Mogale, 2020. Seasonal variations of phytochemical content and antioxidant activity of Senna italica leaves. Asian J. Chem., 32: 2371-2374.
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Mogale, M., C. Mhlanga, S. Gololo and A. Adu, 2019. Ellisras longitudinal study 2017: elevated serum levels of carboxymethyl-lysine, an advanced glycation end-product, are associated with higher odds of developing endothelial dysfunction in black south African patients with type 2 diabetes mellitus (ELS 29). CardioVasc. J. Africa, 30: 193-197.
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Gololo,S.S., S.D. Makhubela, T. Tshidino and M.A. Mogale, 2019. Purification and characterization of proteases from cow dung: validation of an ancient african home treatment for burn wounds. Ann. Burns Fire Disasters, 32: 103-114.
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Gololo, S.S., D. Nthai and M.A. Mogale, 2019. Phytochemical contents and antioxidant capacity of the leaves of aloe greatheadii var. davyana from four south African provinces. Asian J. Chem., 31: 1830-1834.
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Molefe, N.I., M.A. Mogale and S.S. Gololo, 2018. Qualitative and quantitative phytochemical analysis of leaves and roots of barleria dinteri with varying exposure to road-dust pollution. Asian J. Chem., 30: 2521-2526.
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Gololo, S.S., N.S. Mapfumari and M.A. Mogale, 2018. Comparative quantitative phytochemical analysis of the leaves of senna italica collected from different areas in limpopo province, south Africa. Int. J. Pharm. Pharm. Sci., 10: 67-71.
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Olivier, M.T., F.M. Muganza, L.J. Shai, S.S. Gololo and L.D. Nemutavhanani, 2017. Phytochemical screening, antioxidant and antibacterial activities of ethanol extracts of Asparagus suaveolens aerial parts. S. Afr. J. Bot., 108: 41-46.
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Gololo, S.S., M.A. Mogale, L.J. Shai, N.M. Agyei and P. Masoko, 2017. Effect of concoction extraction of the leaves of Barleria dinteri (Oberm), Grewia flava (DC) and Jatropha lagarinthoides (Sond) on inherent antioxidant and antibacterial activities. Res. J. Med. Plants, 11: 14-18.
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Olivier, M.T., F.M. Muganza, L.J. Shai and S.S. Gololo, 2016. In vitro antigonorrhea activity of the aerial part of asparagus suaveolens n-hexane fraction and palmitone as a bioactive compound. Nat. Prod. Commun., 11: 1319-1321.
Gololo, S.S., N.S. Mapfumari, L.S. Sethoga, M.T. Olivier, L.J. Shai and M.A. Mogale, 2016. Identification of phytochemical constituents within the n-hexane leaf extract of Senna italica (Mill) using Gas Chromatography-Mass Spectrometry (GC-MS) analysis. J. Pharm. Sci. Res., 8: 1141-1143.
Gololo, S.S., L.J. Shai, N.M. Agyei and M.A. Mogale, 2016. Effect of seasonal changes on the quantity of phytochemicals in the leaves of three medicinal plants from Limpopo Province, South Africa. J. Pharmacogn. Phytother., 8: 168-172.
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Gololo, S.S., L.J. Shai, L. Sethoga, N. Agyei, K.E. Bassey and M.A. Mogale, 2016. Isolation of a mixture of phytosterol compounds from the n-hexane extract of Jatropha lagarinthoides (Sond) collected from Zebediela sub-region in Limpopo province, South Africa. J. Chem. Pharm. Sci., 9: 3084-3087.
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Gololo, S.S., N.S. Mapfumari, L.J. Shai and M.A. Mogale, 2016. Comparison of the TLC R_f values and UV-Visible spectral profiles of the leaf extracts of Senna italica collected from four districts in Limpopo province, South Africa. J. Chem. Pharmaceut. Res., 8: 144-148.
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Mokgotho, M.P., S.S. Gololo, P. Masoko, L.K. Mdee and V. Mbazima et al., 2013. Isolation and chemical structural characterization of a compound with antioxidant with antioxidant activity from the roots of Senna italica. Evidence-Based Complementary Altern. Med., 10.1155/2013/519174.
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Masoko, P., S.S. Gololo, M.P. Mokgotho, J.N. Eloff, R.L. Howard and L.J. Mampuru, 2010. Evaluation of the antioxidant, antibacterial and antiproliferative activities of the acetone extract of roots of Senna italic (Fabaceae). Afr. J. Trad. Comp. Alt. Med., 7: 138-148.
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