Dr. Pedro Miguel Ribeiro Viana Baptista
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Dr. Pedro Miguel Ribeiro Viana Baptista

Associate Professor
Universidade Nova de Lisboa, Portugal


Highest Degree
Ph.D. in Human Molecular Genetics from University of London, UK

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Area of Interest:

Molecular Sciences
100%
Molecular Genetics
62%
Biotechnology
90%
Nanodiagnostics
75%
Gene Therapy
55%

Research Publications in Numbers

Books
0
Chapters
16
Articles
203
Abstracts
17

Selected Publications

  1. Veigas, B., R. Branquinho, J.V. Pinto, P.J. Wojcik, R. Martins, E. Fortunato and P.V. Baptista, 2014. Ion sensing (EIS) real-time quantitative monitorization of isothermal DNA amplification. Biosens. Bioelectron., 52: 50-55.
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  2. Quaresma, P., I. Osorio, G. Doria, P.A. Carvalho and A. Pereira et al., 2014. Star-shaped magnetite@gold nanoparticles for protein magnetic separation and SERS detection. RSC Adv., 4: 3659-3667.
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  3. Conde, J., M. Larguinho, A. Cordeiro, L.R. Raposo and P.M. Costa et al., 2014. Gold-Nanobeacons for gene therapy: evaluation of genotoxicity, cell toxicity and proteome profiling analysis. Nanotoxicology, 8: 521-532.
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  4. Veigas, B., P. Pedrosa, I. Couto, M. Viveiros and P.V. Baptista, 2013. Isothermal DNA amplification coupled to Au-nanoprobes for detection of mutations associated to Rifampicin resistance in Mycobacterium tuberculosis. J. Nanobiotechnol., Vol. 11. 10.1186/1477-3155-11-38.
    CrossRef  |  Direct Link  |  
  5. Larguinho, M., P.M. Costa, G. Sousa, M.H. Costa, M.S. Diniz and P.V. Baptista, 2013. Histopathological findings on Carassius auratus hepatopancreas upon exposure to acrylamide: Correlation with genotoxicity and metabolic alterations. J. Applied Toxicol. (In Press). 10.1002/jat.2936.
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  6. Larguinho, M., J.L. Capelo and P.V. Baptista, 2013. Fast nucleotide identification through fingerprinting using gold nanoparticle-based surface-assisted laser desorption/ionization. Talanta, 105: 417-421.
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  7. Cordeiro, M., L. Giestas, J.C. Lima and P. Baptista, 2013. Coupling an universal primer to SBE combined spectral codification strategy for single nucleotide polymorphism analysis. J. Biotechnol., 168: 90-94.
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  8. Conde, J., J.M. de la Fuente and P.V. Baptista, 2013. Nanomaterials for reversion of multidrug resistance in cancer: A new hope for an old idea? Front. Pharmacol., Vol. 4. 10.3389/fphar.2013.00134.
    CrossRef  |  Direct Link  |  
  9. Conde, J., J. Rosa, J.M. de la Fuente and P.V. Baptista, 2013. Gold-nanobeacons for simultaneous gene specific silencing and intracellular tracking of the silencing events. Biomaterials, 34: 2516-2523.
    CrossRef  |  
  10. Conde, J., F. Tian, Y. Hernandez, C. Bao and D. Cui et al., 2013. In vivo tumor targeting via nanoparticle-mediated therapeutic siRNA coupled to inflammatory response in lung cancer mouse models. Biomaterials, 34: 7744-7753.
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  11. Carlos, F.F., J. Silva-Nunes, O. Flores, M. Brito, G. Doria, L. Veiga and P.V. Baptista, 2013. Association of FTO and PPARG polymorphisms with obesity in Portuguese women. Diabetes Metab. Syndrome Obesity, 6: 241-245.
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  12. Cabral, R.M. and P.V. Baptista, 2013. The chemistry and biology of gold nanoparticle-mediated photothermal therapy: Promises and challenges. Nano Life, Vol. 3, No. 3. 10.1142/S179398441330001X.
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  13. Branquinho, R., J.V. Pinto, T. Busani, P. Barquinha and L. Pereira et al., 2013. Plastic compatible sputtered Ta2O5 sensitive layer for oxide semiconductor TFT sensors. J. Display Technol., 9: 723-728.
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  14. Bernacka-Wojcik, I., P. Lopes, A.C. Vaz, B. Veigas and P.J. Wojcik et al., 2013. Bio-microfluidic platform for gold nanoprobe based DNA detection: Application to Mycobacterium tuberculosis. Biosens. Bioelectron., 48: 87-93.
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  15. Veigas, B., J.M. Jacob, M.N. Costa, D.S. Santos and M. Viveiros et al., 2012. Gold on paper-paper platform for Au-nanoprobe TB detection. Lab Chip, 12: 4802-4808.
    CrossRef  |  PubMed  |  
  16. Sanz, V., J. Conde, Y. Hernandez, P.V. Baptista, M.R. Ibarra and J.M. de la Fuente, 2012. Effect of PEG biofunctional spacers and TAT peptide on dsRNA loading on gold nanoparticles. J. Nanoparticle Res., Vol. 14. 10.1007/s11051-012-0917-2.
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  17. Rosa, J., J. Conde, J.M. de la Fuente, J.C. Lima and P.V. Baptista, 2012. Gold-nanobeacons for real-time monitoring of RNA synthesis. Biosens. Bioelectron., 36: 161-167.
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  18. Machado, D., I. Couto, J. Perdigao, L. Rodrigues and I. Portugal et al., 2012. Contribution of efflux to the emergence of isoniazid and multidrug resistance in Mycobacterium tuberculosis. PLoS ONE, Vol. 7. 10.1371/journal.pone.0034538.
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  19. Larguinho, M. and P.V. Baptista, 2012. Gold and silver nanoparticles for clinical diagnostics: From genomics to proteomics. J. Proteomics, 75: 2811-2823.
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  20. Guirgis, B.S.S., C. Sa e Cunha, I. Gomes, M. Cavadas and I. Silva et al., 2012. Gold nanoparticle-based fluorescence immunoassay for Malaria antigen detection. Anal. Bioanal. Chem., 402: 1019-1027.
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  21. Dos Santos, M.M., M.J. Queiroz and P.V. Baptista, 2012. Enhancement of antibiotic effect via gold: Silver-alloy nanoparticles. J. Nanoparticle Res., Vol. 14. 10.1007/s11051-012-0859-8.
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  22. Doria, G., J. Conde, B. Veigas, L. Giestas and C. Almeida et al., 2012. Noble metal nanoparticles for biosensing applications. Sensors, 12: 1657-1687.
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  23. Conde, J., P.V. Baptista, Y. Hernandez, V. Sanz and J.M. de la Fuente, 2012. Modification of plasmid DNA topology by histone-mimetic gold nanoparticles. Nanomedicine, 7: 1657-1666.
    CrossRef  |  PubMed  |  Direct Link  |  
  24. Conde, J., J. Rosa, J.C. Lima and P.V. Baptista, 2012. Nanophotonics for molecular diagnostics and therapy applications. Int. J. Photoenergy. 10.1155/2012/619530.
    CrossRef  |  Direct Link  |  
  25. Conde, J., G. Doria, J.M. de la Fuente, P.V. Baptista, 2012. RNA Quantification using Noble Metal Nanoprobes-Application to Cancer Diagnostics. In: Nanoparticles in Biology and Medicine: Methods and Protocols (Methods in Molecular Biology, Volume 906), Soloviev, M. (Ed.). Chapter 6, Humana Press, USA., ISBN-13: 9781617799525, pp: 71-87.
  26. Conde, J., G. Doria and P. Baptista, 2012. Noble metal nanoparticles applications in cancer. J. Drug Delivery. 10.1155/2012/751075.
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  27. Conde, J., A. Ambrosone, V. Sanz, Y. Hernandez and V. Marchesano et al., 2012. Design of multifunctional gold nanoparticles for in vitro and in vivo gene silencing. ACS Nano, 6: 8316-8324.
    CrossRef  |  Direct Link  |  
  28. Baptista, P.V., 2012. RNA quantification with gold nanoprobes for cancer diagnostics. Clin. Lab. Med., 32: 1-13.
    CrossRef  |  Direct Link  |  
  29. Baptista, P.V., 2012. Could gold nanoprobes be an important tool in cancer diagnostics? Expert Rev. Mol. Diagn., 12: 541-543.
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  30. Veigas, B., G. Doria and P.V. Baptista, 2011. Nanodiagnostics for Tuberculosis. In: Understanding Tuberculosis: Global Experiences and Innovative Approaches to the Diagnosis, Cardona, P.J. (Ed.). Chapter 12, InTech Publishers, Rijeka, Croatia, ISBN: 978-953-307-938-7, pp: 257-276.
    Direct Link  |  
  31. Rosa, J.P., J.C. Lima and P.V. Baptista, 2011. Experimental photophysical characterization of fluorophores in the vicinity of gold nanoparticles. Nanotechnology, Vol. 22. 10.1088/0957-4484/22/41/415202.
    CrossRef  |  Direct Link  |  
  32. Giestas, L., J.C. Lima and P.V. Baptista, 2011. Coupling single base extension to a spectral codification tool for increased throughput screening. J. Biotechnol., 154: 199-204.
    CrossRef  |  Direct Link  |  
  33. Branquinho, R., B. Veigas, J.V. Pinto, R. Martins, E. Fortunato and P.V. Baptista, 2011. Real-time monitoring of PCR amplification of proto-oncogene c-MYC using a Ta2O5 electrolyte-insulator-semiconductor sensor. Biosens. Bioelectron., 28: 44-49.
    CrossRef  |  Direct Link  |  
  34. Baptista, P.V., G. Doria, P. Quaresma, M. Cavadas and C.S. Neves et al., 2011. Nanoparticles in molecular diagnostics. Prog. Mol. Biol. Transl. Sci., 104: 427-488.
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  35. Baptista, P.V., G. Doria, P. Quaresma, M. Cavadas and C.S. Neves et al., 2011. Nanoparticles in Molecular Diagnostics. In: Progress in Molecular Biology and Translational Science, Volume 104: Nanoparticles in Translational Science and Medicine, Villaverde, A. (Ed.). Chapter 11, Academic Press, USA., ISBN-13: 9780124160200, pp: 427-488.
  36. Veigas, B., D. Machado, J. Perdigao, I. Portugal, I. Couto, M. Viveiros and P.V. Baptista, 2010. Au-nanoprobes for detection of SNPs associated with antibiotic resistance in Mycobacterium tuberculosis. Nanotechnology, Vol. 21. 10.1088/0957-4484/21/41/415101.
    CrossRef  |  Direct Link  |  
  37. Silva, L.B., B. Veigas, G. Doria, P. Costa and J. Inacio et al., 2010. Portable optoelectronic biosensing platform for identification of mycobacteria from the Mycobacterium tuberculosis complex. Biosens. Bioelectron., 26: 2012-2017.
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  38. Pinheiro, A.V., J. Conde, A.J. Parola, J.C. Lima and P.V. Baptista, 2010. Use of cyclodextrins as scavengers of inhibitory photo-products in light controlled in vitro synthesis of RNA. J. Photochem. Photobiol. A: Chem., 213: 147-151.
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  39. Pinheiro, A.V., A.J. Parola, P.V. Baptista and J.C. Lima, 2010. pH effect on the photochemistry of 4-methylcoumarin phosphate esters: Caged-phosphate case study. J. Phys. Chem. A, 114: 12795-12803.
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  40. Neves, C.S., P. Quaresma, P.V. Baptista, P.A. Carvalho, J.P. Araujo, E. Pereira and P. Eaton, 2010. New insights into the use of magnetic force microscopy to discriminate between magnetic and nonmagnetic nanoparticles. Nanotechnology, Vol. 21. 10.1088/0957-4484/21/30/305706.
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  41. Larguinho, M., H.M. Santos, G. Doria, H. Scholz, P.V. Baptista and J.L. Capelo, 2010. Development of a fast and efficient ultrasonic-based strategy for DNA fragmentation. Talanta, 81: 881-886.
    CrossRef  |  
  42. Doria, G., M. Larguinho, J.T. Dias, E. Pereira, R. Franco and P.V. Baptista, 2010. Gold-silver-alloy nanoprobes for one-pot multiplex DNA detection. Nanotechnology, Vol. 21. 10.1088/0957-4484/21/25/255101.
    CrossRef  |  Direct Link  |  
  43. Doria, G., B.G. Baumgartner, R. Franco and P.V. Baptista, 2010. Optimizing Au-nanoprobes for specific sequence discrimination. Colloids Surf. B: Biointerfaces, 77: 122-124.
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  44. Costa, P., A. Amaro, A. Botelho, J. Inacio and P.V. Baptista, 2010. Gold nanoprobe assay for the identification of mycobacteria of the Mycobacterium tuberculosis complex. Clin. Microbiol. Infect., 16: 1464-1469.
    CrossRef  |  Direct Link  |  
  45. Conde, J., J.M. de la Fuente and P.V. Baptista, 2010. RNA quantification using gold nanoprobes-application to cancer diagnostics. J. Nanobiotechnol., Vol. 8. 10.1186/1477-3155-8-5.
    CrossRef  |  Direct Link  |  
  46. Conde, J., J.M. de la Fuente and P.V. Baptista, 2010. In vitro transcription and translation inhibition via DNA functionalized gold nanoparticles. Nanotechnology, Vol. 21. 10.1088/0957-4484/21/50/505101.
    CrossRef  |  Direct Link  |  
  47. Bernacka-Wojcik, I., R. Senadeera, P.J. Wojcik, L.B. Silva and G. Doria et al., 2010. Inkjet printed and doctor blade TiO2 photodetectors for DNA biosensors. Biosens. Bioelectron., 25: 1229-1234.
    CrossRef  |  Direct Link  |  
  48. Giestas, L., V. Petrov, P.V. Baptista and J.C. Lima, 2009. General FRET-based coding for application in multiplexing methods. Photochem. Photobiol. Sci., 8: 1130-1138.
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  49. Baptista, P.V., 2009. Cancer nanotechnology-prospects for cancer diagnostics and therapy. Curr. Cancer Therapy Rev., 5: 80-88.
    CrossRef  |  
  50. Silva, L.B., P.V. Baptista, L. Raniero, G. Doria, R. Martins and E. Fortunato, 2008. Characterization of optoelectronic platform using an amorphous/nanocrystalline silicon biosensor for the specific identification of nucleic acid sequences based on gold nanoparticle probes. Sens. Actuator B: Chem., 132: 508-511.
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  51. Pinheiro, A.V., P.V. Baptista and J.C. Lima, 2008. Light activation of transcription: photocaging of nucleotides for control over RNA polymerization. Nucleic Acids Res., Vol. 36. 10.1093/nar/gkn415.
    CrossRef  |  Direct Link  |  
  52. Martins, R., P. Baptista, L. Silva, L.V. Raniero, G. Doria, R. Franco and E. Fortunato, 2008. Identification of unamplified genomic DNA sequences using gold nanoparticle probes and a novel thin film photodetector. J. Non-Cryst. Solids, 354: 2580-2584.
    CrossRef  |  Direct Link  |  
  53. Giestas, L., G.N.M. Ferreira, P.V. Baptista and J.C. Lima, 2008. Multiplexed spectral coding for simultaneous detection of DNA hybridization reactions based on FRET. Sens. Actuator B: Chem., 134: 146-157.
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  54. Baptista, P.V., E. Pereira, P. Eaton, G. Doria and A. Miranda et al., 2008. Gold nanoparticles for the development of clinical diagnosis methods. Anal. Bioanal. Chem., 391: 943-950.
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  55. Martins, R., P.V. Baptista, L. Raniero, G. Doria, L. Silva, R. Franco and E. Fortunato, 2007. Amorphous/nanocrystalline silicon biosensor for the specific identification of unamplified nucleic acid sequences using gold nanoparticle probes. Applied Phys. Lett., Vol. 90. 10.1063/1.2431449.
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  56. Gaspar, J.F., P.V. Baptista and J. Rueff, 2007. Gold nanoparticle based systems in genetics. Curr. Pharmacogenomics, 5: 39-47.
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  57. Eaton, P., G. Doria, E. Pereira, P.V. Baptista and R. Franco, 2007. Imaging gold nanoparticles for DNA sequence recognition in biomedical applications. IEEE Trans. NanoBiosci., 6: 282-288.
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  58. Doria, G., R. Franco and P. Baptista, 2007. Nanodiagnostics: Fast colorimetric method for single nucleotide polymorphism/mutation detection. IET Nanobiotechnol., 1: 53-57.
    CrossRef  |  Direct Link  |  
  59. Baptista, P.V., M. Koziol-Montewka, J. Paluch-Oles, G. Doria and R. Franco, 2006. Gold-nanoparticle-probe-based assay for rapid and direct detection of Mycobacterium tuberculosis DNA in clinical samples. Clin. Chem., 52: 1433-1434.
    CrossRef  |  Direct Link  |  
  60. Baptista, P.V., G. Doria, D. Henriques, E. Pereira and R. Franco, 2005. Colorimetric detection of eukaryotic gene expression with DNA-derivatized gold nanoparticles. J. Biotechnol., 119: 111-117.
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  61. Baptista, P.V., 2005. Principles in genetic risk assessment. Ther. Clin. Risk Manage., 1: 15-20.
    PubMed  |  
  62. Groet, J., J.H. Ives, A.P. South, P.R. Baptista and T.A. Jones et al., 1998. Bacterial contig map of the 21q11 region associated with Alzheimer's disease and abnormal myelopoiesis in down syndrome. Genome Res., 8: 385-389.
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  63. Flomen, R.H., R. Vatcheva, P.A. Gorman, P.R. Baptista and J. Groet et al., 1998. Construction and analysis of a sequence-ready map in 4q25: Rieger syndrome can be caused by haploinsufficiency of RIEG, but also by chromosome breaks ≈90 kb upstream of this gene. Genomics, 47: 409-413.
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