Dr. Domenico  Capone
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Dr. Domenico Capone

Assistant Professor
University of Naples Federico II, Italy


Highest Degree
Ph.D. in Nephrology from University of Naples Federico II, Italy

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Area of Interest:

Pharmacology and Toxicology
100%
Toxicology
62%
Neurology
90%
Cardiology
75%
Dermatology
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
83
Abstracts
13

Selected Publications

  1. Tarantino, G., D. Capone and C. Finelli, 2013. Exposure to ambient air particulate matter and non-alcoholic fatty liver disease. World J. Gastroenterol., 19: 3951-3956.
    CrossRef  |  PubMed  |  Direct Link  |  
  2. Tarantino, G. and D. Capone, 2013. Inhibition of the mTOR pathway: A possible protective role in coronary artery disease. Ann. Med., 45: 348-356.
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  3. Polichetti, G., D. Capone, K. Grigoropoulos, G. Tarantino, A. Nunziata and A. Gentile, 2013. Effects of ambient air pollution on birth outcomes: An overview. Crit. Rev. Environ. Sci. Technol., 43: 752-774.
    CrossRef  |  Direct Link  |  
  4. Tarantino, G., C. Finelli, A. Colao, D. Capone and M. Tarantino et al., 2012. Are hepatic steatosis and carotid intima media thickness associated in obese patients with normal or slightly elevated gamma-glutamyl-transferase? J. Transl. Med., Vol. 10. 10.1186/1479-5876-10-50.
    CrossRef  |  PubMed  |  Direct Link  |  
  5. Tarantino, G., S. Savastano, D. Capone and A. Colao, 2011. Spleen: A new role for an old player? World J. Gastroenterol., 17: 3776-3784.
    CrossRef  |  PubMed  |  Direct Link  |  
  6. Tarantino, G., S. Savastano, A. Colao, G. Polichetti and D. Capone, 2011. Urinary excretion of 5-hydroxy-3-indoleacetic acid in dystimic/depressed, adult obese women: What correlations to hepatic steatosis? Int. J. Immunopathol. Pharmacol., 29: 769-779.
    PubMed  |  Direct Link  |  
  7. Tarantino, G., F. Scopacasa, A. Colao, D. Capone, M. Tarantino, E. Grimaldi and S. Savastano, 2011. Serum Bcl-2 concentrations in overweight-obese subjects with nonalcoholic fatty liver disease. World J. Gastroenterol., 17: 5280-5288.
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  8. Tarantino, G., A. Colao, D. Capone, P. Conca and M. Tarantino et al., 2011. Circulating levels of cytochrome C, gamma-glutamyl transferase, triglycerides and unconjugated bilirubin in overweight/obese patients with non-alcoholic fatty liver disease. J. Biol. Regul. Homeost. Agents, 25: 47-56.
    PubMed  |  Direct Link  |  
  9. Pignataro, G., D. Capone, G. Polichetti, A. Vinciguerra, A. Gentile, G. Di Renzo and L. Annunziato, 2011. Neuroprotective, immunosuppressant and antineoplastic properties of mTOR inhibitors: Current and emerging therapeutic options. Curr. Opinion Pharmacol., 11: 378-394.
    CrossRef  |  PubMed  |  Direct Link  |  
  10. Pieri, M., N. Miraglia, G. Polichetti, G. Tarantino, A. Acampora and D. Capone, 2011. Analytical and pharmacological aspects of therapeutic drug monitoring of mTOR inhibitors. Curr. Drug Metab., 3: 253-267.
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  11. Capone, D., G. Tarantino, I. Kadilli, G. Polichetti, V. Basile, S. Federico and M. Sabbatini, 2011. Evalutation of mycophenolic acid systemic exposure by limited sampling strategy in kidney transplant recipients receiving enteric-coated mycophenolate sodium (EC-MPS) and cyclosporine. Nephrol. Dial. Transplant., 26: 3019-3025.
    PubMed  |  Direct Link  |  
  12. Tarantino, G., G. Palmiero, G. Polichetti, A. Perfetti and M. Sabbatini et al., 2010. Long-term assessment of plasma lipids in transplant recipients treated with tacrolimus in relation to fatty liver. Int. J. Immunopathol. Pharmacol., 23: 1303-1308.
    PubMed  |  Direct Link  |  
  13. Capone, D., G. Tarantino, G. Polichetti, I. Kadilli and M. Sabbatini et al., 2010. Absence of pharmacokinetic interference of moxifloxacin on cyclosporine and tacrolimus in kidney transplant recipients. J. Clin. Pharmacol., 50: 576-580.
    CrossRef  |  PubMed  |  Direct Link  |  
  14. Capone, D., G. Tarantino, A. Gentile, M. Sabbatini and G. Polichetti et al., 2010. Effects of voriconazole on tacrolimus metabolism in a kidney transplant recipient. J. Clin. Pharm. Ther., 35: 121-124.
    CrossRef  |  PubMed  |  Direct Link  |  
  15. Tarantino, G., V. Citro, P. Conca, A. Riccio and M. Tarantino et al., 2009. What are the implications of the spontaneous spleno-renal shunts in liver cirrhosis? BMC Gastroenterol., Vol. 9. 10.1186/1471-230X-9-89.
    CrossRef  |  PubMed  |  Direct Link  |  
  16. Tarantino, G., P. Conca, M. Tarantino, M.N.D. Di Minno and E. Grimaldi et al., 2009. Does spleen volume play a role in patients with HCV-related chronic hepatitis. Int. J. Immunopathol. Pharmacol., 22: 1009-1017.
    PubMed  |  
  17. Tarantino, G., P. Colicchio, P. Conca, C. Finelli and D.M.N. Di Minno et al., 2009. Young adult obese subjects with and without insulin resistance: What is the role of chronic inflammation and how to weigh it non-invasively. J. Inflammation, 6: 1-6.
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  18. Tarantino, G., M.N.D. Di Minno and D. Capone, 2009. Drug-induced liver injury: Is it somehow foreseeable. World J. Gastroenterol., 15: 2817-2833.
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  19. Tarantino, G., G. Pezzullo, M.N.D. di Minno, F. Milone, L.S. Pezzullo, M. Milone and D. Capone, 2009. Drug-induced liver injury due to herbal extract of Lycopodium serratum and Chelidonium maius mimicking acute cholangitis-cholecistitis: A case report. World J. Gastroenterol., 15: 2414-2417.
  20. Sabbatini, M., D. Capone, R. Gallo, A. Pisani and G. Polichetti et al., 2009. EC-MPS permits lower gastrointestinal symptom burden despite higher MPA exposure in patients with severe MMF-related gastrointestinal side-effects. Fundam. Clin. Pharmacol., 23: 617-624.
    CrossRef  |  PubMed  |  Direct Link  |  
  21. Tarantino, G., V. Basile, P. Conca, M. Ariello and M.N.D. Di Minno et al., 2008. Could the depression of obese patients suffering from chronic hepatitis C be temporarily improved? J. Viral Hepatitis, 15: 646-650.
    CrossRef  |  PubMed  |  Direct Link  |  
  22. Tarantino, G., P. Conca, A. Riccio, M. Tarantino and M.N. Di Minno et al., 2008. Enhanced serum concentrations of transforming growth factor-beta1 in simple fatty liver: Is it really benign? J. Trans. Med., 6: 72-72.
    CrossRef  |  PubMed  |  Direct Link  |  
  23. Striano, S., P. Striano, D. Capone and F. Pisani, 2008. Limited place for plasma monitoring of new antiepileptic drugs in clinical practice. Med. Sci. Monit., 14: RA173-RA178.
    PubMed  |  Direct Link  |  
  24. Pieri, M., N. Miraglia, A. Gentile, G. Polichetti and L. Castiglia et al., 2008. Quantification of sirolimus and everolimus by immunoassay techniques: test specificity and cross-reactivity evaluation. Int. J. Immunopathol. Pharmacol., 21: 585-594.
    PubMed  |  
  25. Capone, D., A. Gentile, G. Polichetti, S. Federico and M. Sabbatini et al., 2008. Stability of sirolimus and everolimus measured by immunoassay techniques in whole blood samples from kidney transplant patients. Int. J. Immunopathol. Pharmacol., 21: 297-307.
    PubMed  |  
  26. Tarantino, G., P. Conca, V. Basile, A. Gentile, D. Capone, G. Polichetti and E. Leo, 2007. A prospective study of acute drug-induced liver injury in patients suffering from non-alcoholic fatty liver disease. Hepatol. Res., 37: 410-415.
    CrossRef  |  PubMed  |  Direct Link  |  
  27. Tarantino, G., A. Gentile, D. Capone, V. Basile and M. Tarantino et al., 2007. Does protracted antiviral therapy impact on HCV-related liver cirrhosis progression. World J. Gastroenterol., 13: 4903-4908.
    PubMed  |  
  28. Pieri, M., D. Capone, A. Gentile, N. Miraglia and E. Leo et al., 2007. Immunoassay determination of rapamycin: Reliability of the method with respect to liquid chromatography mass spectrometric quantification. Clin. Transplant., 21: 633-637.
    CrossRef  |  PubMed  |  Direct Link  |  
  29. Capone, D., G. Palmiero, A. Gentile, V. Basile and S. Federico et al., 2007. A pharmacokinetic interaction between clarithromycin and sirolimus in kidney transplant recipient. Curr. Drug Metab., 8: 379-381.
    PubMed  |  Direct Link  |  
  30. Tarantino, G., P. Conca, D. Capone, A. Gentile, G. Polichetti and V. Basile, 2006. Reliability of Total Overnight Salivary Caffeine Assessment (TOSCA) for liver function evaluation in compensated cirrhotic patients. Eur. J. Clin. Pharmacol., 62: 605-612.
    CrossRef  |  PubMed  |  Direct Link  |  
  31. Federico, S., R. Carrano, D. Capone, A. Gentile, G. Palmiero and V. Basile, 2006. Pharmacokinetic interaction between levofloxacin and ciclosporin or tacrolimus in kidney transplant recipients. Clin. Pharmacokinet., 45: 169-175.
    CrossRef  |  PubMed  |  Direct Link  |  
  32. Costagliola, C., L. Mastropasqua, D. Capone, M. Verolino, M. Ciancaglini and N. Pisanti, 2000. Effect of fluoxetine on intraocular pressure in the rabbit. Exp. Eye Res., 70: 169-175.
    CrossRef  |  PubMed  |  Direct Link  |  
  33. Capone, D., A. Spano, A. Gentile, G. Ferrara and E. Itto et al., 2000. Are there differences in methotrexate kinetics between responding and nonresponding patients with rheumatoid arthritis? BioDrugs, 13: 373-379.
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  34. Capone, D., P. Stanziale, A. Gentile, P. Imperatore, T. Pellegrino and V. Basile, 1999. Effects of simvastatin and pravastatin on hyperlipidemia and cyclosporin blood levels in renal transplant recipients. Am. J. Nephrol., 19: 411-415.
    CrossRef  |  PubMed  |  Direct Link  |  
  35. Capone, D., A. Gentile, P. Imperatore, G. Palmiero and V. Basile, 1999. Effects of itraconazole on tacrolimus blood concentrations in a renal transplant recipient. Ann. Pharmacother., 33: 1124-1125.
    CrossRef  |  PubMed  |  Direct Link  |  
  36. Capone, D., A. Gentile, F. Morra and V. Basile, 1999. Comparison of three immunoassays for digoxin therapeutic monitoring: TDxII, OPUS and IMx. J. Applied Therapeutic Res., 2: 291-297.
  37. Capone, D., A. Gentile and V. Basile, 1999. Possibile interference of digoxin-like immunoreactive substances using the digoxin fluorescence polarization immunoassay. J. Applied Therapeutic Res., 2: 305-308.
  38. Capone, D., V. De Marino, N. Caso, P. Stanziale and R. Fontana et al., 1998. Polyclonal/monoclonal ratio in kidney and bone marrow transplanted patients treated with cyclosporine. Clin. Transplantation, 12: 430-433.
    PubMed  |  Direct Link  |  
  39. Capone, D., A. Gentile, P. Vajro, P. Stanziale and P. Imperatore et al., 1998. Therapeutic monitoring of tacrolimus in pediatric and adult transplanted patients. J. Chemother., 10: 176-178.
    PubMed  |  Direct Link  |  
  40. Capone, D., V. De Marino, R. Fontana, R. Notaro, V. De Marino and N. Pisanti, 1997. Effects of different routes of cyclosporin A administration on blood levels in patients undergoing bone marrow transplantation. Bone Marrow Transplantation, 19: 369-372.
    PubMed  |  Direct Link  |  
  41. Capone, D., C. Aiello, G.A. Santoro, A. Gentile and P. Stanziale et al., 1996. Drug interaction between cyclosporine and two antimicrobial agents, josamycin and rifampicin, in organ-transplanted patients. Int. J. Clin. Pharmacol. Res., 16: 73-76.
    PubMed  |  Direct Link  |  
  42. Capone, D., V. De Marino, N. Pisanti and V. De Marino, 1994. A new dry chemistry immunoassay: Comparison with a fluorescence polarization system. Eur. Rev. Med. Pharmacol. Sci., 16: 91-94.
    PubMed  |  Direct Link  |  
  43. Capone, D., P. Stanziale, M.M. Balletta, P. Imperatore, V. De Marino and N. Pisanti, 1992. Evaluation of monoclonal/polyclonal ratio in kidney transplanted patients treated with cyclosporine. Int. J. Clin. Pharmacol. Res., 12: 123-128.
    PubMed  |  Direct Link  |  
  44. Memoli, B., C. Libetta, M. Sabbatini, G. Conte and D. Russo et al., 1991. Renal functional reserve: Its significance in normal and salt depletion conditions. Kidney Int., 40: 1134-1140.
    PubMed  |  Direct Link  |  
  45. De Marino, V., N. Pisanti and D. Capone, 1991. Effects of nimodipine on psychological-stress situation in aged rats. Acta Neurol., 13: 410-417.
    PubMed  |  Direct Link  |  
  46. Ferrara, L.A., M. Mancini, G. De Simone, N. Pisanti, D. Capone, M.L. Fasano and M. Mancini, 1989. Adrenergic nervous system and left ventricular mass in primary hypertension. Eur. Heart J., 10: 1036-1040.
    PubMed  |  Direct Link  |  
  47. Pisanti, N., V. De Marino, D. Capone, A. Gentile and U. Giani, 1988. Effects of theophylline on netilmicin and gentamicin disposition in rats. Med. Sci. Res., 16: 1305-1306.
  48. Pisanti, N., P. Stanziale, P. Imperatore, R. D'Alessandro, V. De Marino, D. Capone and V. De Marino, 1988. Lack of effect of gemfibrozil on cyclosporine blood concentrations in kidney-transplanted patients. Am. J. Nephrol., 18: 199-203.
    CrossRef  |  PubMed  |  Direct Link  |  
  49. Ferrara, L.A., T.S. Moscato, N. Pisanti, T. Marotta, V. Krogh, D. Capone and M. Mancini, 1988. Is the sympathetic nervous system altered in children with familial history of arterial hypertension? Cardiology, 75: 200-205.
    PubMed  |  
  50. Capone, D., A. Del Rio, G. Campanella, V. De Marino and N. Pisanti, 1988. Pharmacokinetics of some antiepileptics. Boll. Soc. Ital. Biol. Sperimentale, 64: 17-23.
  51. Delfino, M., R. Acri, S. Mangone, N. Pisanti and D. Capone, 1987. The role of biogenic amines in the pathogenesis of alopecia areata. Ital. General Rev. Dermatol., 24: 239-242.
  52. De Marino, V., N. Pisanti, D. Capone, A. Annicelli, M. Del Donno and S.A. Marsico, 1986. Effects of betamethasone on theophylline disposition in man. Are saliva values predictive of serum theophylline levels? Pharm. Res. Communi., 18: 909-921.
    PubMed  |  
  53. De Marino, V., N. Pisanti and D. Capone, 1986. Effects of trazodone and bicuculline on conditioning-avoidance in the rat. Boll. Soc. Ital. Biol. Sper., 62: 871-875.
    PubMed  |  
  54. De Natale, G., A. Lucisano, S. Damiano, D. Capone and G. Basile, 1985. Lack of substantial neuroendocrine changes in short-term high dose cadmium treated rats. Arch. Toxicol., 8: 327-328.
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  55. De Michele, G., V. Brescia-Morra, N. Pisanti, U. Giani and L. Filla et al., 1985. Carbamazepine serum levels in epileptics. Influence of age, sex, body weight and interaction with phenobarbital. Acta Neurol., 7: 228-234.
    PubMed  |  
  56. Pisanti, N., V. De Marino, D. Capone and A. Gentile, 1983. Lack of effects of amiodarone on serum levels of theophylline in rats. Rassegna Med. Sperimentale, 30: 84-88.
  57. De Marino, V., N. Pisanti, A. Gentile and D. Capone, 1983. Pharmacokinetic interaction between betamethasone and theophylline in the rat. Rassegna Med. Sperimentale, 30: 1-5.