Dr. Federica  Pellati

Dr. Federica Pellati

Assistant Professor
University of Modena and Reggio Emilia, Italy


Highest Degree
Ph.D. in Pharmaceutical Sciences from University of Modena and Reggio Emilia, Italy

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Area of Interest:

Pharmacology and Toxicology
100%
Immunopharmacology
62%
Ethnopharmacology
90%
Phytochemistry
75%
Chromatography
55%

Selected Publications

  1. Pellati, F. and G. Rastelli, 2016. Novel and less explored chemotypes of natural origin for the inhibition of Hsp90. MedChemComm, 7: 2063-2075.
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  2. Cannas, S., D. Usai, R. Tardugno, S. Benvenuti, F. Pellati, S. Zanetti and P. Molicotti, 2016. Chemical composition, cytotoxicity, antimicrobial and antifungal activity of several essential oils. Nat. Prod. Res., 30: 332-339.
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  3. Borsari, C., R. Luciani, C. Pozzi, I. Poehner and S. Henrich et al., 2016. Profiling of flavonol derivatives for the development of antitrypanosomatidic drugs. J. Med. Chem., 59: 7598-7616.
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  4. Sait, S., S. Hamri-Zeghichi, L. Boulekbache-Makhlouf, K. Madani and P. Rigou et al., 2015. HPLC-UV/DAD and ESI-MSn analysis of flavonoids and antioxidant activity of an Algerian medicinal plant: Paronychia argentea Lam. J. Pharmaceut. Biomed. Anal., 111: 231-240.
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  5. Mapelli, J., D. Gandolfi, E. Giuliani, F.P. Prencipe and F. Pellati et al., 2015. The effect of desflurane on neuronal communication at a central synapse. PloS One, Vol. 10. 10.1371/journal.pone.0123534.
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  6. Lorenzo, M.P., D. Dudzik, E. Varas, M. Gibellini and M. Skotnicki et al., 2015. Optimization and validation of a chiral GC-MS method for the determination of free d-amino acids ratio in human urine: Application to a gestational diabetes mellitus study. J. Pharmaceut. Biomed. Anal., 107: 480-487.
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  7. Franchini, S., A. Baraldi, C. Sorbi, F. Pellati and E. Cichero et al., 2015. Enantiomeric resolution of [(2, 2-diphenyl-1, 3-dioxolan-4-yl) methyl](2-phenoxyethyl) amine, a potent α1 and 5-HT1A receptor ligand: An in vitro and computational study. MedChemComm, 6: 677-690.
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  8. Prencipe, F.P., V. Brighenti, M. Rodolfi, A. Mongelli and C. Dall'Asta et al., 2014. Development of a new high-performance liquid chromatography method with diode array and electrospray ionization-mass spectrometry detection for the metabolite fingerprinting of bioactive compounds in Humulus lupulus L. J. Chromatogr. A, 1349: 50-59.
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  9. Prencipe, F.P., R. Bruni, A. Guerrini, D. Rossi, S. Benvenuti and F. Pellati, 2014. Metabolite profiling of polyphenols in Vaccinium berries and determination of their chemopreventive properties. J. Pharmaceut. Biomed. Anal., 89: 257-267.
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  10. Prencipe, F.P., F. Pellati, V. Brighenti, S. Benvenuti and R. Bruni, 2014. An innovative approach for the phytochemical analysis of bioactive compounds in Humulus lupulus L. La Chimica L'Industria, 5/6: 48-49.
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  11. Pellati, F., 2014. Innovative Methods for the Extraction and Chromatographic Analysis of Honey Bee Products. In: Instrumental Methods for the Analysis and Identification of Bioactive Molecules, Jayprakasha, G.K. and F. Pellati (Eds.)., Chapter 2, ACS Symposium Series, Volume 1185, Oxford University Press, UK., ISBN-13: 9780841229761, pp: 33-49.
  12. Mahfoudhi, A., F.P. Prencipe, Z. Mighri and F. Pellati, 2014. Metabolite profiling of polyphenols in the Tunisian plant Tamarix aphylla (L.) Karst. J. Pharmaceut. Biomed. Anal., 99: 97-105.
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  13. Pellati, F., S. Benvenuti, F. Prati and P. Nieri, 2013. Isolation, Structure Elucidation, Synthesis and Cytotoxic Activity of Polyacetylenes and Polyenes from Echinacea pallida. In: Emerging Trends in Dietary Components for Preventing and Combating Disease, Patil, B.S., G.K. Jayaprakasha, K.N.C. Murthy and N.P. Seeram (Eds.)., Chapter 8, ACS Symposium Series, Volume 1093, Oxford University Press, ISBN: 9780841226647, UK., pp: 131-149.
  14. Pellati, F., R. Bruni, D. Righi, A. Grandini and M. Tognolini et al., 2013. Metabolite profiling of polyphenols in a Terminalia chebula Retzius ayurvedic decoction and evaluation of its chemopreventive activity. J. Ethnopharmacol., 147: 277-285.
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  15. Pellati, F., G. Orlandini, K.A. Leeuwen, G. Anesin and D. Bertelli et al., 2013. Gas chromatography combined with mass spectrometry, flame ionization detection and elemental analyzer/isotope ratio mass spectrometry for characterizing and detecting the authenticity of commercial essential oils of Rosa damascene mill. Rapid Commun. Mass Spectrometry, 27: 591-602.
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  16. Pellati, F., F.P. Prencipe, D. Bertelli and S. Benvenuti, 2013. An efficient chemical analysis of phenolic acids and flavonoids in raw propolis by microwave-assisted extraction combined with high-performance liquid chromatography using the fused-core technology. J. Pharmaceut. Biomed. Anal., 81: 126-132.
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  17. Pellati, F., F.P. Prencipe and S. Benvenuti, 2013. Headspace solid-phase microextraction-gas chromatography-mass spectrometry characterization of propolis volatile compounds. J. Pharmaceut. Biomed. Anal., 84: 103-111.
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  18. Ferrari, S., F. Pellati and M.P. Costi, 2013. Protein-Protein Interaction Inhibitors: Case Studies on Small Molecules and Natural Compounds. In: Disruption of Protein-Protein Interfaces: In Search of New Inhibitors, Mangani, S. (Ed.)., Chapter 2, Springer-Verlag, Berlin, Heidelberg, ISBN: 978-3-642-37998-7, pp: 31-60.
  19. Pellati, F., G. Orlandini and S. Benvenuti, 2012. Simultaneous metabolite fingerprinting of hydrophilic and lipophilic compounds in Echinacea pallid by high-performance liquid chromatography with diode array and electrospray ionization-mass spectrometry detection. J. Chromatogr. A, 1242: 43-58.
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  20. Garcia, A., F.J. Ruperez, F. Ceppa, F. Pellati and C. Barbas, 2012. Development of chromatographic methods for the determination of genotoxic impurities in cloperastine fendizoate. J. Pharmaceut. Biomed. Anal., 61: 230-236.
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  21. Pellati, F., G. Orlandini, D. Pinetti and S. Benvenuti, 2011. HPLC-DAD and HPLC-ESI-MS/MS methods for metabolite profiling of propolis extracts. J. Pharm. Biomed. Anal., 55: 934-948.
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  22. Pellati, F., F. Epifano, N. Contaldo, G. Orlandini and L. Cavicchi et al., 2011. Chromatographic methods for metabolite profiling of virus-and phytoplasma-infected plants of Echinacea purpurea. J. Agric. Food Chem., 59: 10425-10434.
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  23. Iannuccelli, V., M. Montanari, D. Bertelli, F. Pellati and G. Coppi, 2011. Microparticulate polyelectrolyte complexes for gentamicin transport across intestinal epithelia. Drug Delivery, 18: 26-37.
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  24. Fiocco, D., D. Fiorentino, L. Frabboni, S. Benvenuti, G. Orlandini, F. Pellati and A. Gallone, 2011. Lavender and peppermint essential oils as effective mushroom tyrosinase inhibitors: A basic study. Flavour Fragrance J., 26: 441-446.
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  25. Pellati, F., G. Cannazza and S. Benvenuti, 2010. Study on the racemization of synephrine by off-column chiral high-performance liquid chromatography. J. Chromatography A, 1217: 3503-3510.
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  26. Iffiu-Soltesz, Z., E. Wanecq, A. Lomba, M.P. Portillo and F. Pellati et al., 2010. Chronic benzylamine administration in the drinking water improves glucose tolerance, reduces body weight gain and circulating cholesterol in high-fat diet-fed mice. Pharmacol. Res., 61: 355-363.
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  27. Ferrarini, A., A.L. Huidobro, F. Pellati and C. Barbas, 2010. Development and validation of a HPLC method for the determination of sertraline and three non-chiral related impurities. J. Pharm. Biomed. Anal., 53: 122-129.
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  28. Chicca, A., B. Adinolfi, F. Pellati, G. Orlandini, S. Benvenuti and P. Nieri, 2010. Cytotoxic activity and G1 cell cycle arrest of a dienynone from Echinacea pallida. Planta Med., 76: 444-446.
  29. Bondioli, L., L. Costantino, A. Ballestrazzi, D. Lucchesi and D. Boraschi et al., 2010. PLGA nanoparticles surface decorated with the sialic acid, N-acetylneuraminic acid. Biomaterials, 31: 3395-3403.
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  30. Pellati, F., R. Bruni, M.G. Bellardi, A. Bertaccini and S. Benvenuti, 2009. Optimization and validation of a high-performance liquid chromatography method for the analysis of cardiac glycosides in Digitalis lanata. J. Chromatogr. A, 1216: 3260-3269.
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  31. Chicca, A., S. Raduner, F. Pellati, T. Strompen, K.H. Altmann, R. Schoop and J. Gertsch, 2009. Synergistic immunomopharmacological effects of N-alkylamides in Echinacea purpurea herbal extracts. Int. Immunopharmacol., 9: 850-858.
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  32. Romiti, N., F. Pellati, P. Nieri, S. Benvenuti, B. Adinolfi and E. Chieli, 2008. P-glycoprotein inhibitory activity of lipophilic constituents of Echinacea pallida roots in a human proximal tubular cell line. Planta Med., 74: 264-266.
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  33. Pellati, F. and S. Benvenuti, 2008. Determination of ephedrine alkaloids in Ephedra natural products using HPLC on a pentafluorophenylpropyl stationary phase. J. Pharm. Biomed. Anal., 48: 254-263.
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  34. Morandi, S., F. Pellati, S. Benvenuti and F. Prati, 2008. Total synthesis of a dienynone from Echinacea pallida. Tetrahedron, 64: 6324-6328.
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  35. Morandi, S., F. Pellati, C. Ori, B. Adinolfi, P. Nieri, S. Benvenuti and F. Prati, 2008. Isolation, structure elucidation and total synthesis of a cytotoxic dienone from Echinacea pallida. Organic Biomolecular Chem., 6: 4333-4339.
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  36. Chicca, A., F. Pellati, B. Adinolfi, A. Matthias and I. Massarelli et al., 2008. Cytotoxic activity of polyacetylenes and polyenes isolated from roots of Echinacea pallida. Br. J. Pharmacol., 153: 879-885.
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  37. Pellati, F., S. Calo and S. Benvenuti, 2007. High-performance liquid chromatography analysis of polyacetylenes and polyenes in Echinacea pallid by using a monolithic reversed-phase silica column. J. Chromatogr. A, 1149: 56-65.
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  38. Pellati, F. and S. Benvenuti, 2007. Fast high-performance liquid chromatography analysis of phenethylamine alkaloids in Citrus natural products on a pentafluorophenylpropyl stationary phase. J. Chromatogr. A, 1165: 58-66.
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  39. Pellati, F. and S. Benvenuti, 2007. Chromatographic and electrophoretic methods for the analysis of phenetylamine alkaloids in Citrus aurantium. J. Chromatogr. A, 1161: 71-88.
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  40. Chicca, A., B. Adinolfi, E. Martinotti, S. Fogli and M.C. Breschi et al., 2007. Cytotoxic effects of Echinacea root hexanic extracts on human cancer cell lines. J. Ethnopharmacol., 110: 148-153.
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  41. Pellati, F., S. Calo, S. Benvenuti, B. Adinolfi, P. Nieri and M. Melegari, 2006. Isolation and structure elucidation of cytotoxic polyacetylenes and polyenes from Echinacea pallid. Phytochemistry, 67: 1359-1364.
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  42. Pellati, F., S. Benvenuti, F. Yoshizaki and M. Melegari, 2006. Development and validation of HPLC methods for the analysis of phenethylamine and indoloquinazoline alkaloids in Evodia species. J. Sep. Sci., 29: 641-649.
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  43. Pellati, F., S. Benvenuti, F. Yoshizaki, D. Bertelli and M.C. Rossi, 2005. Headspace solid-phase microextraction-gas chromatography-mass spectrometry analysis of the volatile compounds of Evodia species fruits. J. Chromatogr. A, 1087: 265-273.
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  44. Pellati, F., S. Benvenuti and M. Melegari, 2005. Enantioselective LC analysis of synephrine in natural products on a protein-based chiral stationary phase. J. Pharm. Biomed. Anal., 37: 839-849.
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  45. Pellati F., S. Benvenuti, M. Melegari and T. Lasseigne, 2005. Variability in the composition of anti‐oxidant compounds in Echinacea species by HPLC. Phytochem. Anal., 16: 77-85.
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  46. Pellati F., S. Benvenuti and M. Melegari, 2005. Chromatographic performance of a new polar poly(ethylene glycol) bonded phase for the phytochemical analysis of Hypericum perforatum L. J. Chromatogr. A, 1088: 205-217.
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  47. Carpene, C., S. Bour, V. Visentin, F. Pellati and S. Benvenuti et al., 2005. Amine oxidase substrates for impaired glucose tolerance correction. J. Physiol. Biochem., 61: 405-419.
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  48. Bruni, R., F. Pellati, M.G. Bellardi, S. Benvenuti, S. Paltrinieri, A. Bertaccini and A. Bianchi, 2005. Herbal drug quality and phytochemical composition of Hypericum perforatum L. affected by ash yellows phytoplasma infection. J. Agric. Food Chem., 53: 964-968.
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  49. Pellati, F., S. Benvenuti, L. Magro, M. Melegari and F. Soragni, 2004. Analysis of phenolic compounds and radical scavenging activity of Echinacea spp. J. Pharmaceut. Biomed. Anal., 35: 289-301.
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  50. Pellati F., S. Benvenuti and M. Melegari, 2004. High‐performance liquid chromatography methods for the analysis of adrenergic amines and flavanones in Citrus aurantium L. var. amara. Phytochem. Anal., 15: 220-225.
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  51. Benvenuti, S., F. Pellati, M. Melegari and D. Bertelli, 2004. Polyphenols, anthocyanins, ascorbic acid and radical scavenging activity of Rubus, Ribes and Aronia. J. Food Sci., 69: FCT164-FCT169.
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  52. Pellati, F., S. Benvenuti, M. Melegari and F. Firenzuoli, 2002. Determination of adrenergic agonists from extracts and herbal products of Citrus aurantium L. var. amara by LC. J. Pharm. Biomed. Anal., 29: 1113-1119.
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